Publications ORBi OA
Bookmark and Share    
Full Text
See detailPotential antimalarial activity of indole alkaloids
Angenot, Luc ULg

in 42nd International meeting on medicinal chemistry- Program and abstracts (2006, July)

Detailed reference viewed: 23 (0 ULg)
Full Text
Peer Reviewed
See detailA nation-wide pilot project for early rehabilitation of low back pain workers
Mairiaux, Philippe ULg; DELARUELLE D.; STRAUSS, Patrick

in IEA 2006 Proccedings (2006, July)

As a result of both a political and a scientific thinking, the Belgian Fund for Occupational Diseases (FOD) has launched, starting March 1st 2005, a pilot project for the nursing staff in the health care ... [more ▼]

As a result of both a political and a scientific thinking, the Belgian Fund for Occupational Diseases (FOD) has launched, starting March 1st 2005, a pilot project for the nursing staff in the health care sector in order to prevent the transition of low back pain (LBP) to chronicity through a program promoting an early return to work. Target workers are those being off work due to LBP for at least 4 weeks and maximum 3 months. The program involves a standardised multidisciplinary back rehabilitation program on the one hand, and on the other hand an ergonomics intervention in the health care institution. Depending on the context, the workplace intervention may involve an ergonomic analysis with the participation of the sicklisted worker, a larger group-based ergonomics redesign, or temporary change in the worker duty or work time in order to facilitate his/her return to work. The employer gets a financial incentive from the FOD when he agrees to such an intervention. Due to a lack of communication among the target population, this pilot project has had a slow start; the presentation gives a qualitative overview of the first 100 cases having entered the program. [less ▲]

Detailed reference viewed: 12 (3 ULg)
Full Text
Peer Reviewed
See detailPharmacological evaluation of TP receptor antagonists characterized by differential activity on alpha and beta isoforms
Hanson, Julien ULg; Ghiotto, J.; Neven, P. et al

in Acta Pharmacologica Sinica (2006, July), 27

Detailed reference viewed: 13 (1 ULg)
Full Text
Peer Reviewed
See detailDevA, a GntR-like transcriptional regulator required for development in Streptomyces coelicolor
Hoskisson, P. A.; Rigali, Sébastien ULg; Fowler, K. et al

in Journal of Bacteriology (2006), 188(14), 5014-5023

The gram-positive filamentous bacterium Streptomyces coelicolor has a complex developmental cycle with three distinct phases: growth of the substrate mycelium, development of reproductive structures ... [more ▼]

The gram-positive filamentous bacterium Streptomyces coelicolor has a complex developmental cycle with three distinct phases: growth of the substrate mycelium, development of reproductive structures called aerial hyphae, and differentiation of these aerial filaments into long chains of exospores. During a transposon mutagenesis screen, we identified a novel gene (devA) required for proper development. The devA mutant produced only rare aerial hyphae, and those that were produced developed aberrant spore chains that were much shorter than wild-type chains and had misplaced septa. devA encodes a member of the GntR superfamily, a class of transcriptional regulators that typically respond to metabolite effector molecules. devA forms an operon with the downstream gene devB, which encodes a putative hydrolase that is also required for aerial mycelium formation on R5 medium. S1 nuclease protection analysis showed that transcription from the single devA promoter was temporally associated with vegetative growth, and enhanced green fluorescent protein transcriptional fusions showed that transcription was spatially confined to the substrate hyphae in the wild type. In contrast, devAB transcript levels were dramatically upregulated in a devA mutant and the devA promoter was also active in aerial hyphae and spores in this background, suggesting that DevA might negatively regulate its own production. This suggestion was confirmed by gel mobility shift assays that showed that DevA binds its own promoter region in vitro. [less ▲]

Detailed reference viewed: 34 (0 ULg)
Full Text
Peer Reviewed
See detailUnderstanding and supporting collaborative design using an horizontal tabletop display
Safin, Stéphane ULg; Leclercq, Pierre ULg; Decortis, Françoise ULg

in Proceedings of the IEA2006. 16th World Congress on Ergonomics (2006, July)

Based on our research on evaluating a Virtual desk environment for architects and designers is it possible to derive requirements for supporting collaborative design activities ? We first examine ... [more ▼]

Based on our research on evaluating a Virtual desk environment for architects and designers is it possible to derive requirements for supporting collaborative design activities ? We first examine questions related to internal and external interactions in architectural design, to the role of external representations and their extension as shared objects of design in collaborative horizontal tabletop. Then we describe the Virtual Desktop and the EsQUIsE software. We will synthesize the results of our former investigations on this setting, in order to derive new orientations for the design and research. [less ▲]

Detailed reference viewed: 45 (6 ULg)
Full Text
See detailLa maison Bacot restaurée. La reconnaissance de Clément Pirnay (Verviers, 1881 - Chimay, 1955)
Charlier, Sébastien ULg

in Nouvelles du Patrimoine (Les) (2006), 112

Detailed reference viewed: 96 (9 ULg)
Full Text
Peer Reviewed
See detailAssessment of Ultimate Bending Moment of Ships from a Reliability Point of View, Using Independent Perturbations Method
Toderan, Catalin; Richir, Thomas; Caprace, Jean-David ULg et al

in Network for Integrating Structural Safety, Risk and Reliability (ASRANet) (2006, July)

This paper presents a method to asses hull girder ultimate bending moment distribution, taking into account parameters uncertainty. This method is a part of a research activity carried out at University ... [more ▼]

This paper presents a method to asses hull girder ultimate bending moment distribution, taking into account parameters uncertainty. This method is a part of a research activity carried out at University of Liege. The method is able to compute four statistical moments of ultimate strength distribution: average, standard deviation, skewness and kurtosis. Geometry parameters, material parameters and initial imperfections (initial deflections and residual stresses) are considered as random variables and a distribution is associated to each of them. Ultimate bending moment algorithm is a progressive collapse analysis based on Smith method and associated with the load-end shortening model proposed by Bureau Veritas and Joint Bulker Project Rules (JBP). In order to perform a reliability analysis, this algorithm is coupled with independent perturbations method. The advantage is a lower number of simulations compared to the standard Monte-Carlo procedure and a good use of the initial information that is available. The paper contains also a comparative analysis between the presented method and a linear sensitivity analysis performed by the ISSC 2000 “Ultimate Strength” committee for a VLCC structure. [less ▲]

Detailed reference viewed: 135 (7 ULg)
Full Text
Peer Reviewed
See detailPhenomenal characteristics of autobiographical memories for social and non-social events in social phobia
D'Argembeau, Arnaud ULg; Van der Linden, Martial ULg; d'Acremont, Mathieu et al

in Memory (2006), 14(5), 637-647

Previous studies failed to show clear differences between people with social phobia and non-anxious individuals regarding the specificity and affective intensity of their autobiographical memories for ... [more ▼]

Previous studies failed to show clear differences between people with social phobia and non-anxious individuals regarding the specificity and affective intensity of their autobiographical memories for social events. However, these studies did not assess the subjective experience associated with remembering. In this study, people with social phobia and non-anxious control participants recalled social and non-social events, and rated the phenomenal characteristics of their memories. The memories of people with social phobia for social events contained fewer sensorial details but more self-referential information than controls memories. In addition, people with social phobia remembered social situations from an observer perspective, viewing themselves as if from outside, to a greater extent than controls. By contrast, the two groups did not differ concerning their memories for non-social events. These findings are discussed in relation to cognitive models of social phobia. [less ▲]

Detailed reference viewed: 54 (5 ULg)
Full Text
Peer Reviewed
See detailPoly(D,L-lactide) (PDLLA) foams with TiO2 nanoparticles and PDLLA/TiO2-Bioglass (R) foam composites for tissue engineering scaffolds
Boccaccini, Aldo R.; Blaker, Jonny J.; Maquet, Véronique et al

in Journal of Materials Science (2006), 41(13), 3999-4008

Porous poly(D,L-lactide) PDLLA foams containing 0, 5 and 20 wt% of TiO2 nanoparticles were fabricated and characterised. The addition of Bioglassg particles was also studied in a composite containing 5 wt ... [more ▼]

Porous poly(D,L-lactide) PDLLA foams containing 0, 5 and 20 wt% of TiO2 nanoparticles were fabricated and characterised. The addition of Bioglassg particles was also studied in a composite containing 5 wt% of Bioglass(R) particles and 20 wt% of TiO2 nanoparticles. The microstructure of the four different foam types was characterised using scanning electron microscopy (SEM) and their mechanical properties assessed by quasi-static compression testing. The in vitro behaviour of the foams was studied in simulated body fluid (SBF) at three different time points: 3, 21 and 28 days. The degradation of the samples was characterised quantitatively by measuring the water absorption and weight loss as a function of immersion time in SBE The bioactivity of the foams was characterised by observing hydroxyapatite (HA) formation after 21 days of immersion in SBF using SEM and confirmed with X-ray diffraction (XRD) analysis. It was found that the amount of HA was dependent on the distribution of TiO2 nanoparticles and on the presence of Bioglassg in the foam samples. (c) 2006 Springer Science + Business Media, Inc. [less ▲]

Detailed reference viewed: 95 (6 ULg)
Full Text
Peer Reviewed
See detailReport of two cases of gastric cancer after bariatric surgery: Lymphoma of the bypassed stomach after Roux-en-Y gastric bypass and gastrointestinal stromal tumor (GIST) after vertical banded gastroplasty
De Roover, Arnaud ULg; Detry, Olivier ULg; de Leval, Laurence ULg et al

in Obesity Surgery (2006), 16(7), 928-931

We report two new cases of gastric cancer diagnosed after a bariatric operation. The first case is a 66-year-old male who 3 years after gastric bypass suffered from a perforation of the fundus that was ... [more ▼]

We report two new cases of gastric cancer diagnosed after a bariatric operation. The first case is a 66-year-old male who 3 years after gastric bypass suffered from a perforation of the fundus that was found to be secondary to a diffuse large B-cell lymphoma of the distal stomach. The second case is a 47-year-old woman who presented 12 years after a vertical banded gastroplasty with a gastric pouch outlet obstruction caused by a gastrointestinal stromal tumor (GIST). Based on the few reports of cancer in the literature, analysis of these cases suggests that the main risk of gastric cancer after bariatric surgery comes from the delayed diagnosis of malignancy. [less ▲]

Detailed reference viewed: 78 (3 ULg)
Full Text
See detailSustainability of certified production systems : the case of labels in the food sector
Van Huylenbroeck, Guido; Steurbaut, Willy; Mormont, Marc ULg et al

Report (2006)

In a label initiative, the stakeholders are manifold but most important are the producers and producers’associations, the retail sector, the public authorities, the control organisations, environmental ... [more ▼]

In a label initiative, the stakeholders are manifold but most important are the producers and producers’associations, the retail sector, the public authorities, the control organisations, environmental NGO’s, consumer representatives and so on. The basic hypothesis investigated is that the prevailing rules of a label are constructed in such a way that the common objectives of all these stakeholders are maximised while minimising the negative impacts of the label on each of them (e.g. maximising the market share while minimising the cost for producers, retail sector, control cost for both public authorities andcertifying organisations and so on). This can explain differences among labels depending who has been initiating the label or certificate or because of differences in power structure among the stakeholders, but also provide reasons why labels are evolving in a certain way or are not going further although improvements could be possible. The research was based on analysing different labels in the fruit and vegetable sector who have as one of their main objectives to reduce the effects of pesticides on the public health and the environment. Following research questions were analysed: 1. what is the impact of the label or certification rules on farm practices and may these differences ineffects on farm management explain differences in success of labels among farmers; 2. can the environmental impacts of the rules within a label be assessed and can this be an objective basis for analysing differences in emphasis among labels and for evaluating possible improvements in existing labels; 3. are there differences in the social construction of labels, ad who does impact the way labels change farmers’ practices; 4. how do consumers formulate the question of pesticides and do labels provide adequate responses to these questions 5. how do farmers and other stakeholders formulate the question of pesticides and does this influences their view on labelling strategies 6. how do farmers react on possible trajectories to change the rules in a label ? [less ▲]

Detailed reference viewed: 101 (5 ULg)
Full Text
Peer Reviewed
See detailOlfactory ensheathing cells, olfactory nerve fibroblasts and biomatrices to promote long-distance axon regrowth and functional recovery in the dorsally hemisected adult rat spinal cord
Deumens, R.; Koopmans, G. C.; Honig, W. M. M. et al

in Experimental Neurology (2006), 200(1), 89-103

Cellular transplantation, including olfactory ensheathing cells (OEC) and olfactory nerve fibroblasts (ONF), after experimental spinal cord injury in the rat has previously resulted in regrowth of severed ... [more ▼]

Cellular transplantation, including olfactory ensheathing cells (OEC) and olfactory nerve fibroblasts (ONF), after experimental spinal cord injury in the rat has previously resulted in regrowth of severed corticospinal (CS) axons across small lesion gaps and partial functional recovery. In order to stimulate CS axon regrowth across large lesion gaps, we used a multifactorial transplantation strategy to create an OEC/ONF continuum in spinal cords with a 2-mm-long dorsal hemisection lesion gap. This strategy involved the use of aligned OEG/ONF-poly(D,L)-lactide biomatrix bridges within the lesion gap and OEC/ONF injections at I mm rostral and caudal to the lesion gap. In order to test the effects of this complete strategy, control animals only received injections with culture medium rostral and caudal to the lesion gap. Anatomically, our multifactorial intervention resulted in an enhanced presence of injured CS axons directly rostral to the lesion gap (65.0 +/- 12.8% in transplanted animals versus 13.1 +/- 3.9% in control animals). No regrowth of these axons was observed through the lesion site, which may be related to a lack of OEC/ONF survival on the biomatrices. Furthermore, a 10-fold increase of neurofilament-positive axon ingrowth into the lesion site as compared to untreated control animals was observed. With the use of quantitative gait analysis, a modest recovery in stride length and swing speed of the hind limbs was observed. Although multifactorial strategies may be needed to stimulate repair of large spinal lesion gaps, we conclude that the combined use of OEC/ONF and poly(D,L)-lactide biomatrices is rather limited. [less ▲]

Detailed reference viewed: 56 (4 ULg)
Full Text
Peer Reviewed
See detailFrancophonie et études francophones : considérations historiques et métacritiques sur quelques concepts majeurs
Provenzano, François ULg

in Portal : Journal of multidisciplinary international studies (2006), 3(2),

Detailed reference viewed: 23 (4 ULg)
Full Text
See detailPrediction of the reverberation time in rooms with non uniform absorptions using a diffusion model
Billon, Alexis ULg; Sakout, Anas

Conference (2006, July)

The acoustical comfort is now a comfort’s criterion which is taken into from the conception. The designers need therefore accurate tools to predict the acoustic quality of enclosures. Most of the ... [more ▼]

The acoustical comfort is now a comfort’s criterion which is taken into from the conception. The designers need therefore accurate tools to predict the acoustic quality of enclosures. Most of the acoustical comfort criteria are based on the reverberation time. When the room has proportionate dimensions and an uniform absorption, the statistical theory through Sabine or Eyring formulas allows good predictions of the reverberation time. Moreover, extensions of these relations by Millington or Cremer and Müller among others give quite satisfactory when the room is composed of materials with different sound absorption. In this study, the reverberation time in an enclosure is calculated via the numerical resolution of unstationary diffusion equation, model validated in coupled and industrial rooms. Firstly, an improvement of the boundary condition is proposed for highly absorbent surfaces. The diffusion model is then compared to several formulations of the statistical theory and a ray-tracing software for a cubic room with homogeneous walls’ absorption and with non homogeneous walls’ absorptions. Finally, an experimental validation is conducted for an enclosure with non uniformly distributed absorption. [less ▲]

Detailed reference viewed: 55 (4 ULg)
Full Text
See detailFrequency halving due to vortex pairing for the jet-slot oscillator
Billon, Alexis ULg; Glesser, Martin; Valeau, Vincent et al

Conference (2006, July)

At the outlet of the HVCA systems, whistling can occur, due to self-sustained oscillations. In this study, the ventilation outlet is modelled by a free plane subsonic jet impinging on a slotted plate ... [more ▼]

At the outlet of the HVCA systems, whistling can occur, due to self-sustained oscillations. In this study, the ventilation outlet is modelled by a free plane subsonic jet impinging on a slotted plate, leading to self-sustained tones production; this configuration is known as the jet-slot oscillator. The tone's frequency can be predicted through the vortex dynamics within the flow. For jet velocities higher than 16m/s, the tones couple with the flow-supply-duct’s resonances. These resonances control the vortex dynamics and reinforce the sound production, of about 20dB. Moreover, when the distance from the jet exit to the plate is increased and reaches 4.5 times the jet height, the fundamental frequency of the tones is suddenly halved due to some vortex pairing occurring at the end of the potential core of the jet. In this paper, the vortex pairing is observed with three different experimental techniques. Firstly, comparison between the radiated and the in-duct acoustic fields is conducted. Then the energy transfer from the fundamental to the sub-harmonics of the shear layer's velocity fluctuations is observed with anemometric measurements. Finally high speed flow visualizations are performed and allow to link the vortex impingement on the plate to the sound production. [less ▲]

Detailed reference viewed: 29 (0 ULg)
Full Text
See detailTravailler en ville : tout le monde y gagne
Dawance, Sophie ULg

in Imagine Demain le Monde (2006), 56

L’activité économique constitue un élément essentiel à la vie harmonieuse de la cité. Depuis plusieurs décennies pourtant, l’urbanisation de terres agricoles en périphérie des villes et des villages est ... [more ▼]

L’activité économique constitue un élément essentiel à la vie harmonieuse de la cité. Depuis plusieurs décennies pourtant, l’urbanisation de terres agricoles en périphérie des villes et des villages est la réponse généralement apportée à la demande d’espace pour l’activité économique. Conçues à l’origine pour accueillir les activités susceptibles de générer des nuisances pour le voisinage, les zones économiques séduisent aujourd’hui aussi des entreprises tout à fait adaptées au milieu urbain. Les zonings commerciaux ou industriels prolifèrent, tandis que les quartiers urbains se vident peu à peu de leur substrat économique et portent les stigmates de ces abandons successifs. Pourquoi cet exode et quels sont les moyens de ramener l’activité économique au coeur de la cité ? De nombreux exemples de retours ou d’installations heureuses d’entreprises en ville existent à Bruxelles, Liège, Charleroi, mais aussi à Anvers, Gand, ou Roubaix. [less ▲]

Detailed reference viewed: 27 (2 ULg)
Full Text
See detailConservation du caractère reconnaissable par opérations arithmétiques dans un système de numération abstrait
Charlier, Emilie ULg

Master of advanced studies dissertation (2006)

In this thesis, I study the stability of recognizability under arithmetic operations like addition, multiplication by a constant or multiplication, in an abstract numeration system. The main result ... [more ▼]

In this thesis, I study the stability of recognizability under arithmetic operations like addition, multiplication by a constant or multiplication, in an abstract numeration system. The main result presented in this work concerns the abstract numeration system built on the bounded language a^*b^*. It shows that, in this case, multiplication by a constant preserves recognizability if and only if this constant is an odd square. I end this text by providing some partial results of a generalization to abstract numeration system built on any bounded language. [less ▲]

Detailed reference viewed: 44 (4 ULg)
Full Text
See detailIonosphere Crossing of GALILEO Signals
Bidaine, Benoît ULg

Master's dissertation (2006)

The ionosphere plays a crucial role in Global Navigation Satellite Systems (GNSS) accuracy. This electrically charged part of the atmosphere can lead to errors in positioning up to several tens of meters ... [more ▼]

The ionosphere plays a crucial role in Global Navigation Satellite Systems (GNSS) accuracy. This electrically charged part of the atmosphere can lead to errors in positioning up to several tens of meters for single frequency receivers. Therefore its modelling constitutes an important field of study. An empirical model called NeQuick has been chosen to evaluate the ionospheric contribution in GALILEO single frequency users correction. It generates electron densities for given space, time and solar activity conditions from a minimum set of anchor points characteristics. Its use with integration methods allows to calculate total electron contents (TEC) which are directly related to the ionospheric delay. The current GALILEO baseline version of NeQuick is the one published by the Radiocommunication Sector of the International Telecommunication Union (ITU-R) in 2000. From that time, several improvements have been proposed and some problems have been discovered leading to the need of a better understanding and comparison of these different versions and an analysis of the weaknesses. For example research about new topside formulations is currently performed - a new simple proposal has been tested - and the consequences of the daily effective use of NeQuick, which is designed to work with monthly median situations, have to be better known. A software tool with a Graphical User Interface (GUI) has then been developed for the analysis and a comparison between different versions and also between modelled and measured data has been performed. Structuring and analysis of the above-mentioned issues and results of the comparison are detailed in the present document. Solutions or possible paths to investigate solutions are also proposed. [less ▲]

Detailed reference viewed: 253 (41 ULg)