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See detailRole of A Disintegrin and Metalloprotease-12 in Neutrophil Recruitment Induced by Airway Epithelium.
Rocks, Natacha ULg; Estrella, C; Paulissen, Geneviève ULg et al

in American Journal of Respiratory Cell and Molecular Biology (2009), 41(4), 449-58

Among proteases, metalloproteases are implicated in tissue remodeling, as shown in numerous diseases including allergy. ADAMs (A Disintegrin And Metalloprotease) metalloproteases are implicated in ... [more ▼]

Among proteases, metalloproteases are implicated in tissue remodeling, as shown in numerous diseases including allergy. ADAMs (A Disintegrin And Metalloprotease) metalloproteases are implicated in physiologic processes such as cytokine and growth factor shedding, cell migration, adhesion, or repulsion. Our aim was to measure ADAM-12 expression in airway epithelium and to define its role during the allergic response. To raise this question, we analyzed the ADAM-12 expression ex vivo after allergen exposure in patients with allergic rhinitis and in vitro in cultured primary human airway epithelial cells (AEC). Clones of BEAS-2B cells transfected with the full-length form of ADAM-12 were generated to study the consequences of ADAM-12 up-regulation on AEC function. After allergen challenge, a strong increase of ADAM-12 expression was observed in airway epithelium from patients with allergic rhinitis but not from control subjects. In contrast with the other HB-epidermal growth factor sheddases, ADAM-10 and -17, TNF-alpha in vitro increased the expression of ADAM-12 by AEC, an effect amplified by IL-4 and IL-13. Up-regulation of ADAM-12 in AEC increased the expression of alpha3 and alpha4 integrins and to the modulation of cell migration on fibronectin but not on collagen. Moreover, overexpression of ADAM-12 in BEAS-2B enhanced the secretion of CXCL1 and CXCL8 and their capacity to recruit neutrophils. CD47 was strongly decreased by ADAM-12 overexpression, a process associated with a reduced adhesion of neutrophils. These effects were mainly dependent on epidermal growth factor receptor activation. In summary, ADAM-12 is produced during allergic reaction by AEC and might increase neutrophil recruitment within airway mucosa. [less ▲]

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See detailSearching and oviposition behavior of aphidophagous hoverflies (Diptera: Syrphidae): a review
Almohamad, Raki; Verheggen, François ULg; Haubruge, Eric ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2009), 13(3), 467-481

Aphidophagous hoverflies forage according two different host-finding mechanisms: they forage for suitable food sources (for their energy-expensive hovering flight, and for protein to mature their ... [more ▼]

Aphidophagous hoverflies forage according two different host-finding mechanisms: they forage for suitable food sources (for their energy-expensive hovering flight, and for protein to mature their reproductive system), and for suitable oviposition sites. Syrphids are highly mobile, enabling them to lay eggs over large areas, and to locate aphid colonies earlier in the season than other aphidophaga. The result is that most syrphid eggs tend to be laid close to aphid colonies. The choice of oviposition sites may be crucial for offspring performance because the neonate larvae have limited dispersal ability. Selection of aphid patches should therefore reflect nutritional value, risk of predation and competition pressure. Several factors are known to affect the choice of oviposition site: habitat, host plant, aphid species, aphid availability, semiochemicals, the presence of intra-or interspecific competitors and female age. We review here the available information on these factors in order to understand the mechanisms of decision-making by syrphid females during their egg-laying behavior, a crucial aspect of their effective use in strategies of the biological control of aphids. [less ▲]

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See detailA continuous time approach to Robbins' problem of minimizing the expected rank
Bruss, F. Thomas; Swan, Yvik ULg

in Journal of Applied Probability (2009), 46

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See detailEvolution du marché mondial des céréales de 2006/07 à 2008/09
Burny, Philippe ULg

in Centre wallon de Recherches agronomiques; Faculté universitaire des Sciences agronomiques de Gembloux (Eds.) Livre blanc Céréales-Gembloux février 2009 (2009)

Cet article décrit l’évolution récente de la production et des échanges mondiaux des principales céréales et abordent la question des prix.

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See detailTransmission des prix dans le secteur laitier en France
Burny, Philippe ULg

Poster (2009)

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See detailA revised carbon budget for the North Sea
Paetsch, J.; Kuehn, W.; Borges, Alberto ULg et al

Conference (2009)

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See detailPreliminary characterization of jejunocyte and colonocyte cell lines isolated by enzymatic digestion from adult and young cattle.
Loret, Suzanne; Rusu, Dorina; Moualij, Benaissa El et al

in Research in Veterinary Science (2009), 87(1), 123-32

In the present study we developed an enzymatic approach (through the use of collagenase and dispase) to isolate bovine intestinal epithelial cells. Using this method, freshly isolated jejunocytes could be ... [more ▼]

In the present study we developed an enzymatic approach (through the use of collagenase and dispase) to isolate bovine intestinal epithelial cells. Using this method, freshly isolated jejunocytes could be distinguished from simultaneously isolated colonocytes, as the jejunocytes specifically exhibited the small intestinal peptidase gene transcript, as well as an active alkaline phosphatase. The transformation of both types of cell suspension was performed by retroviral infection, using reproduction-defective viruses bearing the gene coding for the large T antigen of the leukaemia simian virus (SV40). The success of the transfection was demonstrated by (1) a significant increase in cell passage numbers (52-53 vs. 7 passages for non-transfected cells), (2) the detection of both the large T transcript and the large T antigen in transformed cells. Possible contamination and progressive substitution of bovine primocultures by non-bovine lineages available in the laboratory was excluded, as the transformed cells presented a bovine typical karyotype. Most transfected cells kept an epithelial morphology after transformation. They also maintained the expression of FABP and enterocyte specific enzymes (brush-border associated maltase and IAP). However, levels of specific activity of these enzymes were low, suggesting that cell differentiation is not completely achieved under the applied culture conditions. [less ▲]

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See detailEfficacité de la technique d’induction florale d’Ananas comosus (L.) Merr. au moyen de charbon actif enrichi à l’éthylène (TIFBio)
Lebeau, Frédéric ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2009), 3

Pineapple is an important export crop for tropical countries. The flower induction treatments are essential to the pineapple production for economical and social reasons. For conventional agriculture ... [more ▼]

Pineapple is an important export crop for tropical countries. The flower induction treatments are essential to the pineapple production for economical and social reasons. For conventional agriculture, many chemicals are available but for organic farming ethylene is the only allowed product. A new flower induction method suited to small organic growers has been developed by the Pesticides Initiative Programme of the Coleacp funded by the European Development Fund. The trials conducted proved that the method reaches more than 80% efficiency at 10 weeks for the different application methods evaluated. The wet application trials show a doses response effect as well as effect of the application replication at 2 days interval. The flowering rate culminates at 100% after 8 weeks for the best results, obtained with the wet treatment at 250 mg per plant applied two times at 2 days interval. The different dry treatments tested gave all 85 – 90% flowering rates at 10 weeks, suggesting the presence of an undetermined limitation factor in the conditions prevailing for the trial. The time of application during the day shows no significant effect. It is concluded that the growers can use the TIFBio technique for production control. It is recommended to evaluate the most suited application technique according to their particular case as environmental effect can affect the efficiency. [less ▲]

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See detailGedragsregels in het financieel recht
Van Cleynenbreugel, Pieter ULg

in Jura Falconis (2009)

This article offers a general introduction into the effects of conduct of business rules imposed by an EU Directive on national financial law. It is the published version of a 'travail écrit' written as a ... [more ▼]

This article offers a general introduction into the effects of conduct of business rules imposed by an EU Directive on national financial law. It is the published version of a 'travail écrit' written as a master student, under the supervision of prof. dr. Herman Cousy (KU Leuven). [less ▲]

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See detailEuropean law in times of European governance. A legal theory inquiry into the doctrinal perceptions of European law and governance
Van Cleynenbreugel, Pieter ULg

in Jura Falconis (2009)

This paper reflects, on a more abstract-theoretical level, on the interplay between law and governance in the European Union. It was written as a course paper for the 'Principles of Law' course at the KU ... [more ▼]

This paper reflects, on a more abstract-theoretical level, on the interplay between law and governance in the European Union. It was written as a course paper for the 'Principles of Law' course at the KU Leuven, Faculty of Law and was subsequently published in the faculty's law review. [less ▲]

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See detailDecentralized reactive power dispatch for a time-varying multi-TSO system
Phulpin, Yannick; Begovic, Miroslav; Petit, Marc et al

in Proceedings of the 42nd Hawaii International Conference on System Sciences (HICSS-42) (2009)

This paper addresses the problem of reactive power dispatch in a power system partitioned into several areas controlled by different transmission system operators. Previous research has shown that nearly ... [more ▼]

This paper addresses the problem of reactive power dispatch in a power system partitioned into several areas controlled by different transmission system operators. Previous research has shown that nearly optimal performance could be achieved in a time-invariant system by using a specific iterative decentralized control scheme with no information exchange. At each iteration of this scheme, every transmission system operator concurrently schedules its own control settings for the next iteration while representing the neighboring areas with external network equivalents. This paper focuses on some parameter tracking techniques to extend the range of application of the decentralized control scheme to time-varying systems, where the time-varying nature of the system is modeled as a succession of steady-state operating conditions with variation of the load demand. Those new techniques are evaluated in the context of IEEE 118 bus system partitioned into three control areas. [less ▲]

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See detailCorrelation between the roughness of the substrate surface and the debonding risk
Perez, Fabien; Morency, Maxim; Bissonnette, Benoît et al

in Alexander, M. G.; Beushausen, H.-D.; Dehn, F. (Eds.) et al Concrete Repair, Rehabilitation and Retrofitting II (2009)

This paper presents the influence of substrate surface preparation on the adhesion strength of repaired beams system. Bond between new and old concrete has been the subject of a number of investigations ... [more ▼]

This paper presents the influence of substrate surface preparation on the adhesion strength of repaired beams system. Bond between new and old concrete has been the subject of a number of investigations, but in most cases, only adhesion strength was addressed. This parameter was used to estimate the durability and/or the debonding risk for repaired structure and it’s a generally accepted auditing standards. Usually, surface preparation of the substrate concrete is considered essential to achieve a durable repair because of its influence on the bond strength. To better understand debonding mechanism, in particular these related to surface preparation, roughness parameters were calculated to quantify the influence of surface preparation on the structural behaviour. Using this approach, repair beams prepared by way of four (4) concrete surface preparations were characterized. Results obtained show that repaired beams presenting a substrate with a rough surface permit to achieve a monolithic behaviour of the repaired system. Opposite structural behaviour, with large debonding, was recorded for those having smooth surface. However, all surface preparations used have promoted the same bond strength regardless the roughness of the substrate. The resulting analysis highlights the relation between roughness parameter αrough and the debonding mechanism of repaired beams. Such results will be useful to better predict the performance of concrete repairs. [less ▲]

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See detailHVDC control strategies to improve transient stability in interconnected power systems
Hazra, Jagabondhu; Phulpin, Yannick; Ernst, Damien ULg

in Proceedings of the 2009 IEEE Bucharest PowerTech (2009)

This paper presents three HVDC modulation strategies to improve transient stability in an interconnected power system. AC variables such as rotor speeds, voltage phasors, and tieline power flows are used ... [more ▼]

This paper presents three HVDC modulation strategies to improve transient stability in an interconnected power system. AC variables such as rotor speeds, voltage phasors, and tieline power flows are used as input to the controller that modifies the power flow settings through the HVDC-links. The proposed techniques are tested on the IEEE 24-Bus reliability test system and critical clearing times obtained for several contingencies are analyzed. The paper shows that HVDC modulation can lead to substantial improvement in transient stability. [less ▲]

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See detailTraitement automatique des langues et langues anciennes
Denooz, Joseph ULg; Rosmorduc, Serge

in Traitement automatique des langues (2009), 50

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See detailMonofluoride Bridged, Binuclear Metallacycles of First Row Transition Metals Supported by Third Generation Bis(1-pyrazolyl)methane Ligands: Unusual Magnetic Properties
Reger, Daniel; Watson, R. P.; Foley, E. A. et al

in Inorganic Chemistry (2009), 48

The reaction of M(BF4)2•xH2O, where M is Fe, Co, Cu, and Zn, and the bitopic, bis(pyrazolyl)methane ligand m-[CH(pz)2]2C6H4, Lm, where pz is a pyrazolyl ring, yields the monofluoride bridged, binuclear ... [more ▼]

The reaction of M(BF4)2•xH2O, where M is Fe, Co, Cu, and Zn, and the bitopic, bis(pyrazolyl)methane ligand m-[CH(pz)2]2C6H4, Lm, where pz is a pyrazolyl ring, yields the monofluoride bridged, binuclear [M2(μ-F)(μ-Lm)2](BF4)3 complexes. In contrast, a similar reaction of Lm with Ni(BF4)2•6H2O yields dibridged [Ni2(μ-F)2(μ-Lm)2](BF4)2. The solid state structures of seven [M2(μ-F)(μ-Lm)2](BF4)3 complexes, with M = Fe, Co, Cu, and Zn, indicate that the divalent metal ion is in a five-coordinate, trigonal bipyramidal, coordination environment with either a linear M–F–M bridging arrangement in five of the complexes, or with a slightly bent Cu–F–Cu bridge in two of the complexes. NMR results indicate that [Zn2(μ-F)(μ-Lm)2](BF4)3 retains its dimeric structure in solution. The [Ni2(μ-F)2(μ-Lm)2](BF4)2 complex has a dibridging fluoride structure that has a six-coordination environment about each nickel(II) ion. In the solid state, the [Fe2(μ-F)(μ-Lm)2](BF4)3 and [Co2(μ-F)(μ-Lm)2](BF4)3 complexes show weak intramolecular antiferromagnetic exchange coupling between the two metal(II) ions with J values of –10.4 and –0.67 cm–1, respectively; there is no observed long-range magnetic order. Three different solvates of [Cu2(μ-F)(μ-Lm)2](BF4)3 are diamagnetic between 5 and 400 K, thus showing strong antiferromagnetic exchange interactions of –600 cm–1 or more negative. Mössbauer spectra indicate that [Fe2(μ-F)(μ-Lm)2](BF4)3 exhibits no long-range magnetic order between 4.2 and 295 K and isomer shifts that are consistent with the presence of five-coordinate, high-spin iron(II). [less ▲]

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See detailModernidades múltiples y crítica social de las tecnologías
Delvenne, Pierre ULg; Erpicum, Martin ULg; Hupet, Pierre et al

in Cuadernos sobre Relaciones Internacionales, Regionalismo y Desarrollo (2009), 4(7), 65-90

Although, the links between the ideologies of progress and technological developments are often strong, we are currently observing amore and more virulent social criticism of these evolutions’ ... [more ▼]

Although, the links between the ideologies of progress and technological developments are often strong, we are currently observing amore and more virulent social criticism of these evolutions’ consequences. This paper,written by four European and Latin American researchers, addresses the way as sciences and technology issues are criticised and dealt with in Europe in the framework of “TechnologyAssessment” (TA) offices. Then, important for the authors is to consider that although TA practices proved to be efficient in a European context, such a tool may not be transferable as such in another context. Relying on the concept of “multiplemodernities”, they focus on Latin America to stress the usefulness of building an adapted local TA capacity, through an interactive process of co-construction by the practitionners and various stakeholders, including the public. [less ▲]

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See detailRésumé C.E. n°185.114, du 2 juillet 2008, ASBL Le Poumon Vert de La Hulpe
Delnoy, Michel ULg

in Aménagement - Environnement (2009), 1

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See detailRésumé C.E. n°185.951, du 29 août 2008, de Clercq
Delnoy, Michel ULg

in Aménagement - Environnement (2009), 2

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See detailLe décret du 31 mai 2007 relatif à la participation du public en matière d'environnement : avancées et questions
Delnoy, Michel ULg; Jadot, Benoît

in Delnoy, Michel (Ed.) Actualités du droit de l'aménagement du territoire et de l'environnement - plans et permis (2009)

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