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See detailModélisation des impacts des changements climatiques sur les ressources en eaux souterraines
Dassargues, Alain ULg

Scientific conference (2004, March 17)

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See detailModélisation des impacts des changements climatiques sur les ressources en eaux souterraines
Dassargues, Alain ULg

Scientific conference (2004, March 15)

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See detailSilica reinforced triblock copolymer gels
Theunissen, E.; Overbergh, N.; Reynaers, H. et al

in Polymer (2004), 45(6), 1857-1865

The effect of silica and polymer coated silica particles as reinforcing agents on the structural and mechanical properties of polystyrene-poly(ethylene/butylene)-polystyrene (PS-PEB-PS) triblock gel has ... [more ▼]

The effect of silica and polymer coated silica particles as reinforcing agents on the structural and mechanical properties of polystyrene-poly(ethylene/butylene)-polystyrene (PS-PEB-PS) triblock gel has been investigated. Different types of chemically modified silica have been compared in order to evaluate the influence of the compatibility between gel and filler. Time-resolved SANS and small-angle X-ray scattering (SAXS) shows that the presence of silica particles affects the ordering of the polystyrene domains during gelsetting. The scattering pattern of silica-reinforced gels reveals strong scattering at very low q, but no structure and formfactor information. However, on heating above the viscoelastic to plastic transition, the 'typical' scattering pattern of the copolymer gel builds-up. All reinforced gels are strengthened by the addition of the reinforcing agent. The transitions from a viscoclastic rubber to a plastic fluid and from a plastic fluid to a viscoelastic liquid are shifted to more elevated temperatures when silica is added to the triblock copolymer gel. [less ▲]

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See detailLes mammites en élevage laitier. Outils et stratégies de diagnostic.
Hanzen, Christian ULg

Conference (2004, March 12)

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See detailETUDE PAR IMAGERIE NUMERIQUE ET GRANULOMETRIE LASER DE L'INFLUENCE DE HUIT ADJUVANTS SUR LA FORMATION DU JET DE PULVERISATION POUR TROIS TYPES DE BUSES.
Stainier, Charles; Lebeau, Frédéric ULg; Straet, S. et al

Conference (2004, March 11)

The liquid sheet characteristics as a function of the adjuvant were measured using digital images. The droplet size distribution was measured using a Malvern particle size analyser. It appears that the ... [more ▼]

The liquid sheet characteristics as a function of the adjuvant were measured using digital images. The droplet size distribution was measured using a Malvern particle size analyser. It appears that the dynamical surface tension plays a critical role in the spray formation. Spray formulation containing Li-700, Silwet L-77, Flofix and Actirob are characterised by a lower dynamical surface tension than those containing Tensiofix D03, Trend 90, Frigate and Break-thru S240. For the three agricultural spray nozzles tested and in comparaison with pure water, the first group shortened the length of the liquid sheet before a perforation break-up mode when the second group lengthened it slightly before a wave disintegration break-up mode. The lengthening of the liquid sheet, is followed by a diminution of the VMD. [less ▲]

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See detailOn the coupling of primary production and calcification at the continental margin
Harlay, Jérôme ULg; Chou, Lei; Roevros, Nathalie et al

Poster (2004, March 05)

Until now, little attention has been paid to the processes controlling the production, dissolution and fate of biogenic calcium carbonate in the oceans. It is however well known that net deposition rates ... [more ▼]

Until now, little attention has been paid to the processes controlling the production, dissolution and fate of biogenic calcium carbonate in the oceans. It is however well known that net deposition rates of inorganic carbon to the sediments are comparable to those of organic matter. There remains still large uncertainties concerning the production and redissolution of biogenic carbonate in the marine system and thus about the role of the carbonate pump in response to anthropogenic CO2 perturbations. The understanding of these processes is also a prerequisite to predict the response of marine organisms to global environmental changes. In the framework of the Belgian global change programme, we have developed a project devoted to the study of the inorganic carbon cycle in the Bay of Biscay where coccolithophorid blooms occur frequently. The study focuses on processes associated with the oceanic production and dissolution of calcium carbonate, by combining field investigations, laboratory experiments and modelling efforts. Remote sensing demonstrates a close relationship between vertical mixing along the continental margin and the development of the phytoplankton bloom. We will present here, results of 14C incorporation experiments used to evaluate the rate of production of organic and inorganic particulate carbon, obtained during a coccolithophorid spring bloom in the investigated area. A tentative mass balance of the carbon fluxes for this area will be presented, confirming the importance that the calcium carbonate pump may play in the oceanic system. [less ▲]

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See detailA process for the synthesis of alkoxyamines and their use in controlled radical polymerization
Detrembleur, Christophe ULg; Gross, Thomas; Meyer, Rolf-Volker

Patent (2004)

PROBLEM TO BE SOLVED: To provide a method for synthesizing an alkoxyamine, and to provide a method for using the same in controlled radical polymerization. ; SOLUTION: This method for synthesizing the ... [more ▼]

PROBLEM TO BE SOLVED: To provide a method for synthesizing an alkoxyamine, and to provide a method for using the same in controlled radical polymerization. ; SOLUTION: This method for synthesizing the alkoxyamine expressed by general formula (I) or (II) [preferably, general formula (I)] comprises a one-pot process, wherein the process includes (1) reacting an oxidizing agent (A) with a sterically hindered secondary amine of general formula (III) in a water-containing medium to form a reaction product and an aqueous phase, (2) removing the aqueous phase, and (3) adding a free radical initiator (B) to the reaction product under such a condition that decomposition of the initiator is promoted to generate free radicals. Further, a method for polymerizing a monomer, namely the method for using the alkoxyamine synthesized by the method with originality, is provided [less ▲]

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See detailnote sous arrêt du 4 mars 2003 "FENIN c/ Commission"
Petit, Nicolas ULg

in Revue du Droit de l'Union Européenne (2004)

Résumé et analyse de l'affaire FENIN contre Commission (affaire T-399/99)

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See detailLong-term multicolour photometry and high-resolution spectroscopy of the two gamma Doradus stars HD 12901 and HD 48501
Aerts, C.; Cuypers, J.; De Cat, P. et al

in Astronomy and Astrophysics (2004), 415

We gathered long-term multicolour Geneva UB[SUB]1[/SUB]BB[SUB]2[/SUB]V[SUB]1[/SUB]VG photometric and high-resolution (R=40 000) spectroscopic data of the two gamma Doradus stars HD 12901 and HD 48501. The ... [more ▼]

We gathered long-term multicolour Geneva UB[SUB]1[/SUB]BB[SUB]2[/SUB]V[SUB]1[/SUB]VG photometric and high-resolution (R=40 000) spectroscopic data of the two gamma Doradus stars HD 12901 and HD 48501. The photometry reveals three frequencies for each of the two stars: f[SUB]1[/SUB]=1.21563 c d[SUP]-1[/SUP], f[SUB]2[/SUB]=1.39594 c d[SUP]-1[/SUP] and f[SUB]3[/SUB]=2.18636 c d[SUP]-1[/SUP] for HD 12901 and f[SUB]1[/SUB]=1.09408 c d[SUP]-1[/SUP], f[SUB]2[/SUB]=1.29054 c d[SUP]-1[/SUP] and f[SUB]3[/SUB]=1.19924 c d[SUP]-1[/SUP] for HD 48501. The photometric amplitude is each time largest in the Geneva B[SUB]1[/SUB] filter and the variations in all the different filters are perfectly in phase within the measurement errors. Mode identification points out that the six modes are all l=1 modes and that the non-adiabatic temperature variations are extremely small, in contradiction to current theoretical predictions. Our spectra show that all the observed frequencies are intrinsic to the stars and cannot be due to binarity. We detect clear line-profile variations at low amplitude (<1 km s[SUP]-1[/SUP]) due to the oscillations of both targets. The estimated v sin i from the spectra are Ë 53 km s[SUP]-1[/SUP] for HD 12901 and Ë 29 km s[SUP]-1[/SUP] for HD 48501. It is at present unclear if the triplet-like structure for HD 48501 is the consequence of rotational splitting or of the large separation expected for high-order gravity modes in the asymptotic regime. Based on observations gathered with the Swiss 0.7 m telescope equipped with the photometer P 7 and with the Swiss 1.2 m Euler telescope equipped with the spectrograph CORALIE, both situated at La Silla, Chile. Reduced data available upon request from the first author. [less ▲]

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See detailIncreased IL-6 and TGF-beta(1) concentrations in bronchoalveolar lavage fluid associated with thoracic radiotherapy
Barthelemy-Brichant, Nicole ULg; Bosquee, Lionel; Cataldo, Didier ULg et al

in International Journal of Radiation, Oncology, Biology, Physics (2004), 58(3), 758-767

PURPOSE: To assess, in lung cancer patients, the effects of thoracic radiotherapy (RT) on the concentrations of transforming growth factor-beta(1) (TGF-beta(1)) and interleukin-6 (IL-6) in the ... [more ▼]

PURPOSE: To assess, in lung cancer patients, the effects of thoracic radiotherapy (RT) on the concentrations of transforming growth factor-beta(1) (TGF-beta(1)) and interleukin-6 (IL-6) in the bronchoalveolar lavage (BAL) fluid. METHODS AND MATERIALS: Eleven patients with lung cancer requiring RT as part of their treatment were studied. BAL was performed bilaterally before, during, and 1, 3, and 6 months after RT. Before each BAL session, the patient's status was assessed clinically using pulmonary function tests and an adapted late effects on normal tissue-subjective, objective, management, analytic (LENT-SOMA) scale, including subjective and objective alterations. The National Cancer Institute Common Toxicity Criteria were used to grade pneumonitis. The TGF-beta(1) and IL-6 levels in the BAL fluid were determined using the Easia kit. RESULTS: The TGF-beta(1) and IL-6 concentrations in the BAL fluid recovered from the irradiated areas were significantly increased by thoracic RT. The increase in TGF-beta(1) levels tended to be greater in the group of patients who developed severe pneumonitis. In the BAL fluid from the nonirradiated areas, the TGF-beta(1) and IL-6 concentrations remained unchanged. CONCLUSION: The observed increase in TGF-beta(1) and IL-6 concentrations in the BAL fluid recovered from the irradiated lung areas demonstrated that these cytokines may contribute to the process leading to a radiation response in human lung tissue. [less ▲]

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See detailInfluence of substrate hydrophobicity on the adsorption of an amphiphilic diblock copolymer
De Cupere, V. M.; Gohy, Jean-François; Jérôme, Robert ULg et al

in Journal of Colloid and Interface Science (2004), 271(1), 60-68

The adsorption of poly(tert-butylmethacrylate)-block-poly(2-(dimethylamino-ethyl) methacrylate) (PtBUMA-b-PDMAEMA) was studied by X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM ... [more ▼]

The adsorption of poly(tert-butylmethacrylate)-block-poly(2-(dimethylamino-ethyl) methacrylate) (PtBUMA-b-PDMAEMA) was studied by X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM) analysis performed on dried samples. The copolymer was dissolved in toluene at concentrations below (0.01 wt%) and above (0.05 and 1 wt%) the CMC; silicon (SiOH) and CH3-grafted silicon (SiCH3) were used as substrates. Whatever the concentration and the substrate, a layer of individual copolymer molecules, 1.5-3 nm thick, formed rapidly. The adsorbed amount was slightly higher and the resistance to AFM tip scraping was stronger on SiOH than oil SiCH3. This is attributed to hydrogen bonding between the PDMAEMA block and the OH groups of the silicon surface, leading to polarization of the adsorbed layer. Above the CMC, on SiOH, randomly scattered dot-like features (about 5 nm high) observed by AFM were attributed to individual micelles, which were not displaced by drying. On SiCH3, the particles found on the top of the adsorbed layer were micelle aggregates, about 50 nm thick, the lateral size of which was strongly influenced by the rate of drying. This further difference between SiCH3 and SiOH is tentatively attributed to the exposure of PDMAEMA by the adsorbed layer formed on SiCH3, while only PtBUMA would be exposed by the layer adsorbed on SiOH. The red blood cell shape and the size of the micelles observed in single layers indicate that the PtBUMA corona was not made compact as a result of drying, (C) 2003 Elsevier Inc. All rights reserved. [less ▲]

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See detailAssociation between polymorphism in IgG Fc receptor IIIa coding gene and biological response to infliximab in Crohn's disease
Louis, Edouard ULg; El Ghoul, Z.; Vermeire, S. et al

in Alimentary Pharmacology & Therapeutics (2004), 19(5), 511-519

AIM: To test the hypothesis of an association between polymorphism in FCGR3A (the gene coding for FcgammaRIIIa, which is expressed on macrophages and natural killer cells, is involved in antibody ... [more ▼]

AIM: To test the hypothesis of an association between polymorphism in FCGR3A (the gene coding for FcgammaRIIIa, which is expressed on macrophages and natural killer cells, is involved in antibody-dependent cell-mediated cytotoxicity and has recently been associated with a positive response to rituximab, a recombinant immunoglobulin G1 antibody used in non-Hodgkin's lymphomas) and response to infliximab in Crohn's disease. METHODS: FCGR3A-158 polymorphism was determined using an allele-specific polymerase chain reaction assay in 200 Crohn's disease patients who had received infliximab for either refractory luminal (n = 142) or fistulizing (n = 58) Crohn's disease. Clinical and biological responses (according to C-reactive protein levels) were assessed in 200 and 145 patients, respectively. RESULTS: There were 82.9% clinical responders in V/V patients vs. 72.7% in V/F and F/F patients (N.S.). Globally, the decrease in C-reactive protein was significantly higher in V/V patients than in F carriers (P = 0.0078). A biological response was observed in 100% of V/V patients, compared with 69.8% of F carriers (P = 0.0002; relative risk, 1.43; 95% confidence interval, 1.27-1.61). In the sub-group of patients with elevated C-reactive protein before treatment, the multivariate analysis selected the use of immunosuppressive drugs and FCGR3A genotype as independent factors influencing the clinical response to infliximab (P = 0.003). CONCLUSION: Crohn's disease patients with FCGR3A-158 V/V genotype have a better biological and, possibly, clinical response to infliximab. [less ▲]

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See detailLe cas clinique du mois. Syndrome de Down et myxoedeme: description d'un cas et revue de la litterature
Serpe, Philippe ULg; Gaillard, J. F.; Serpe, J. N. et al

in Revue Médicale de Liège (2004), 59(3), 131-135

A case of myxedema secondary to undetected hypothyroidism developed in a 48 year old 21-trisomic male. This paper presents a short discussion about different possible diagnoses and a review of the ... [more ▼]

A case of myxedema secondary to undetected hypothyroidism developed in a 48 year old 21-trisomic male. This paper presents a short discussion about different possible diagnoses and a review of the literature concerning the relationship between Down Syndrome and hypothyroidism or other diseases. [less ▲]

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See detailUn bilan des vaccinations en 2002-2003
Miermans, Marie-Christine ULg

in Promouvoir la santé à l'école (2004), (5), 2-3

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See detailNeurohypophysial Receptor Gene Expression by Thymic T Cell Subsets and Thymic T Cell Lymphoma Cell Lines
Hansenne, Isabelle ULg; Rasier, G.; Charlet-Renard, C. et al

in Clinical & Developmental Immunology (2004), 11(1), 45-51

Neurohypophysial oxytocin (OT) and vasopressin (VP) genes are transcribed in thymic epithelium, while immature T lymphocytes express functional neurohypophysial receptors. Neurohypophysial receptors ... [more ▼]

Neurohypophysial oxytocin (OT) and vasopressin (VP) genes are transcribed in thymic epithelium, while immature T lymphocytes express functional neurohypophysial receptors. Neurohypophysial receptors belong to the G protein-linked seven-transmembrane receptor superfamily and are encoded by four distinct genes, OTR, V1R, V2R and V3R. The objective of this study was to identify the nature of neurohypophysial receptor in thymic T cell subsets purified by immunomagnetic selection, as well as in murine thymic lymphoma cell lines RL12-NP and BW5147. OTR is transcribed in all thymic T cell subsets and T cell lines, while V3R transcription is restricted to CD4+CD8+ and CD8+ thymic cells. Neither V1R nor V2R transcripts are detected in any kind of T cells. The OTR protein was identified by immunocytochemistry on thymocytes freshly isolated from C57BL/6 mice. In murine fetal thymic organ cultures, a specific OTR antagonist does not modify the percentage of T cell subsets, but increases late T cell apoptosis further evidencing the involvement of OT/OTR signaling in the control of T cell proliferation and survival. According to these data, OTR and V3R are differentially expressed during T cell ontogeny. Moreover, the restriction of OTR transcription to T cell lines derived from thymic lymphomas may be important in the context of T cell leukemia pathogenesis and treatment. [less ▲]

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