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See detailAtteinte du nerf sus-scapulaire : corrélations entre l’évaluation isocinétique et l’ENMG
Goffinet, Estelle ULg; Mazza, Laetitia; Forthomme, Bénédicte ULg et al

in Neurophysiologie Clinique = Clinical Neurophysiology (2004, May), 34

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See detailElements of muscle's pathology in pediatrics
Battisti, Oreste ULg

Learning material (2004)

This presentations explains how to explore clinically and by investigations muscles movements and pathology, and how to treat muscles' spasticity in children

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See detailEvaluation of the group B differential agar for the detection of group B streptococci from vaginal specimens
MELIN, Pierrette ULg; Rodriguez Cuns, Grisel; Lorquet, Sophie et al

in American Society of Microbiology (Ed.) Program and Abstracts of the 104th General Meeting of the American Society for Microbiology (2004, May)

Background Group B streptococci (GBS) are the leading cause of severe perinatal infections. Most current guidelines for the prevention of GBS perinatal disease are based on prenatal screening culture for ... [more ▼]

Background Group B streptococci (GBS) are the leading cause of severe perinatal infections. Most current guidelines for the prevention of GBS perinatal disease are based on prenatal screening culture for vaginal GBS colonisation. Use of selective and differential media could improve the sensitivity of these cultures. Objective To evaluate the GBS-Differential Agar (GBSDA) recently formulated by Becton Dickinson for the selective growth and production of orange colonies of b- hemolytic (b-H) GBS. Methods 283 vaginal swabs (VAG) collected from pregnant women were inoculated in selective Lim broth. After overnight incubation, Lim broth were subcultured on GBSDA, on Granada agar (Biomedics, Spain) and on Columbia blood agar (BA). To evaluate the stability, 99 isolates of GBS (REF) from adult or neonatal infections (Belgian GBS reference laboratory collection) were cultured on GBSDA and Granada at their limit of expiration, and on BA. GBSDA and Granada were incubated anaerobically and BA aerobically + 7% CO2, at 35°C, 24 to 48 h. Positive and negative control strains (GBS ; E. faecalis) were cultured with each run. Specific identification of colonies suggestive of GBS (pale to dark orange on GBSDA and Granada, b-H on BA) was performed. Results b-H GBS were recovered from 63 VAG (22.3 %): 62 were easily identified after overnight incubation on GBSDA and 63 on Granada without requiring any subculture. All GBS were also recovered from BA however it was after many subcultures. All orange colonies were confirmed as GBS. Among REF, 3 strains were non hemolytic ; they grew but were not differentiated as orange colonies on GBSDA or Granada. 96 REF were b-H, 94 (97.9%) produced orange to very dark orange colonies on GBSDA, 2 produced white colonies, and on Granada, 74 (77.1 %) produced pale to dark orange colonies and 22 white to white-orange colonies. Conclusion 1) GBSDA and Granada: a) very high sensitivity and specificity for the detection of b-H GBS, in a single step b) Results available within 48 h after inoculation in Lim broth, low workload 2) Excellent stability up to expiration date for GBSDA 3) Non hemolytic GBS: grown but not differentiated on GBSDA or Granada. [less ▲]

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See detailL'attaque de panique
Scantamburlo, Gabrielle ULg; Ansseau, Marc ULg

in Revue Médicale de Liège (2004), 59(5), 293-6

Panic attacks can occur unexpectedly and in almost any situation. The present article discusses the main features of anxiety states, the approach, the management and the practice guidelines for the ... [more ▼]

Panic attacks can occur unexpectedly and in almost any situation. The present article discusses the main features of anxiety states, the approach, the management and the practice guidelines for the treatment of panic disorder. [less ▲]

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See detailInfluence of methyl-b-cyclodextrin on the relase kinetics of inulin encapsulated in bioadhesive liposomes
Piel, Géraldine ULg; Boulmedarat, Laila; Bochot, Amélie et al

Poster (2004, May)

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See detailQuel avenir pour nos quartiers ?
Frankignoulle, Pierre ULg; Stevens, Barbara; Herold, Stefan

in Les Echos du logement (2004)

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See detailSecondary-structure characterization by far-UV CD of highly purified uncoupling protein 1 expressed in yeast
Douette, Pierre ULg; Navet, Rachel ULg; Bouillenne, Fabrice ULg et al

in Biochemical Journal (2004), 380(Pt 1), 139-145

The rat UCP1 (uncoupling protein 1) is a mitochondrial inner-membrane carrier involved in energy dissipation and heat production. We expressed UCP1 carrying a His(6) epitope at its C-terminus in ... [more ▼]

The rat UCP1 (uncoupling protein 1) is a mitochondrial inner-membrane carrier involved in energy dissipation and heat production. We expressed UCP1 carrying a His(6) epitope at its C-terminus in Saccharomyces cerevisiae mitochondria. The recombinant-tagged UCP1 was purified by immobilized metal-ion affinity chromatography to homogeneity (>95 %). This made it suitable for subsequent biophysical characterization. Fluorescence resonance energy transfer experiments showed that n-dodecyl-beta-D-maltoside-solubilized UCPI-His(6) retained its PN (purine nucleotide)-binding capacity. The far-UV CD spectrum of the functional protein clearly indicated the predominance of a-helices in the UCP1 secondary structure. The UCP1 secondary structure exhibited an alpha-helical degree of approx. 68 %, which is at least 25 % higher than the previously reported estimations based on computational predictions. Moreover, the helical content remained unchanged in free and PN-loaded UCP1. A homology model of the first repeat of UCP1, built on the basis of X-ray-solved close parent, the ADP/ATP carrier, strengthened the CD experimental results. Our experimental and computational results indicate that (i) alpha-helices are the major component of UCP1 secondary structure; (ii) PN-binding mechanism does not involve significant secondary-structure rearrangement; and (iii) UCP1 shares similar secondary-structure characteristics with the ADP/ATP carrier, at least for the first repeat. [less ▲]

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See detailHealth-related quality of life in total hip and total knee arthroplasty - A qualitative and systematic review of the literature
Ethgen, Olivier ULg; Bruyère, Olivier ULg; Richy, Florent et al

in Journal of Bone & Joint Surgery. American Volume (2004), 86(5), 963-974

BACKGROUND: Total hip and total knee arthroplasties are well accepted as reliable and suitable surgical procedures to return patients to function. Health-related quality-of-life instruments have been used ... [more ▼]

BACKGROUND: Total hip and total knee arthroplasties are well accepted as reliable and suitable surgical procedures to return patients to function. Health-related quality-of-life instruments have been used to document outcomes in order to optimize the allocation of resources. The objective of this study was to review the literature regarding the outcomes of total hip and knee arthroplasties as evaluated by health-related quality-of-life instruments. METHODS: The Medline and EMBASE medical literature databases were searched, from January 1980 to June 2003, to identify relevant studies. Studies were eligible for review if they met the following criteria: (1). the language was English or French, (2). at least one well-validated and self-reported health-related quality of life instrument was used, and (3). a prospective cohort study design was used. RESULTS: Of the seventy-four studies selected for the review, thirty-two investigated both total hip and total knee arthroplasties, twenty-six focused on total hip arthroplasty, and sixteen focused on total knee arthroplasty exclusively. The most common diagnosis was osteoarthritis. The duration of follow-up ranged from seven days to seven years, with the majority of studies describing results at six to twelve months. The Short Form-36 and the Western Ontario and McMaster University Osteoarthritis Index, the most frequently used instruments, were employed in forty and twenty-eight studies, respectively. Seventeen studies used a utility index. Overall, total hip and total knee arthroplasties were found to be quite effective in terms of improvement in health-related quality-of-life dimensions, with the occasional exception of the social dimension. Age was not found to be an obstacle to effective surgery, and men seemed to benefit more from the intervention than did women. When improvement was found to be modest, the role of comorbidities was highlighted. Total hip arthroplasty appears to return patients to function to a greater extent than do knee procedures, and primary surgery offers greater improvement than does revision. Patients who had poorer preoperative health-related quality of life were more likely to experience greater improvement. CONCLUSIONS: Health-related quality-of-life data are valuable, can provide relevant health-status information to health professionals, and should be used as a rationale for the implementation of the most adequate standard of care. Additional knowledge and scientific dissemination of surgery outcomes should help to ensure better management of patients undergoing total hip or total knee arthroplasty and to optimize the use of these procedures. [less ▲]

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See detailPlasmatic cystatin C for the estimation of glomerular filtration rate in intensive care units
Delanaye, Pierre ULg; Lambermont, Bernard ULg; Chapelle, Jean-Paul ULg et al

in Intensive Care Medicine (2004), 30(5), 980-983

OBJECTIVE: To compare the sensitivity of cystatin C and creatinine in detecting decreased glomerular filtration rate. DESIGN: Prospective observational study. SETTING: Medical intensive care unit at a ... [more ▼]

OBJECTIVE: To compare the sensitivity of cystatin C and creatinine in detecting decreased glomerular filtration rate. DESIGN: Prospective observational study. SETTING: Medical intensive care unit at a university hospital. PATIENTS AND PARTICIPANTS: Fourteen patients hospitalised in a medical intensive care unit. INTERVENTIONS: Cystatin C and creatinine plasmatic levels were measured in 40 blood samples taken with an interval of at least 24 h. MEASUREMENTS AND RESULTS: Glomerular filtration rate was estimated by creatinine clearance using 24-h urine collection and the classical Cockcroft-Gault equation. The ability of cystatin C to detect a glomerular filtration rate under 80 ml/min per 1.73 m(2) was significantly better than that of creatinine ( p<0.05). CONCLUSIONS: Cystatin C, a new plasmatic marker of renal function, could be used to detect renal failure in intensive care in the future. [less ▲]

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See detailXMM-Newton observations of the giant H II region N 11 in the LMC
Nazé, Yaël ULg; Antokhin, I. I.; Rauw, Grégor ULg et al

in Astronomy and Astrophysics (2004), 418(3), 841-855

Using the sensitive XMM-Newton observatory, we have observed the giant H II region N11 in the LMC for similar to30 ks. We have detected several large areas of soft diffuse X-ray emission along with 37 ... [more ▼]

Using the sensitive XMM-Newton observatory, we have observed the giant H II region N11 in the LMC for similar to30 ks. We have detected several large areas of soft diffuse X-ray emission along with 37 point sources. One of the most interesting results is the possible association of a faint X-ray source with BSDL 188, a small extended object of uncertain nature, The OB associations in the field-of-view (LH9, LH10 and LH13) are all detected with XMM-Newton, but they appear very different from one another. The diffuse soft X-ray emission associated with LH9 peaks near HD 32228, a dense cluster of massive stars. The combined emission of all individual massive stars of LH9 and of the superbubble they have created is not sufficient to explain the high level of emission observed: hidden SNRs, colliding-wind binaries and the numerous pre-main sequence stars of the cluster are most likely the cause of this discrepancy. The superbubble may also be leaking some hot gas in the ISM since faint, soft emission can be observed to the south of the cluster. The X-ray emission from LH10 consists of three pointlike sources and a soft extended emission of low intensity. The two brightest point sources are clearly associated with the fastest expanding bubbles blown by hot stars in the SW part of the cluster. The total X-ray emission from LH10 is rather soft, although it presents a higher temperature than the other soft emissions of the field. The discrepancy between the combined emission of the stars and the observed luminosity is here less severe than for LH9 and could be explained in terms of hot gas filling the wind-blown bubbles. On the other hand, the case of LH13 is different: it does not harbour any extended emission and its X-ray emission could most probably be explained by the Sk -66degrees41 cluster alone. Finally, our XMM-Newton observation included simultaneous observations with the OM camera that provide us with unique UV photometry of more than 6000 sources and enable the discovery of the UV emission from the SNR N11L. [less ▲]

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See detailDefinition and Classification of Power System Stability
Kundur, Prabha; Paserba, John; Ajjarapu, Venkat et al

in IEEE Transactions on Power Systems (2004), 19(2), 1387-1401

The problem of defining and classifying power system stability has been addressed by several previous CIGRE and IEEE Task Force reports. These earlier efforts, however, do not completely reflect current ... [more ▼]

The problem of defining and classifying power system stability has been addressed by several previous CIGRE and IEEE Task Force reports. These earlier efforts, however, do not completely reflect current industry needs, experiences and understanding. In particular, the definitions are not precise and the classifications do not encompass all practical instability scenarios. This report developed by a Task Force, set up jointly by the CIGRE Study Committee 38 and the IEEE Power System Dynamic Performance Committee, addresses the issue of stability definition and classification in power systems from a fundamental viewpoint and closely examines the practical ramifications. The report aims to define power system stability more precisely, provide a systematic basis for its classification, and discuss linkages to related issues such as power system reliability and security. [less ▲]

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See detailChatter maps for process design of powertrain components
Masset, Luc ULg; Debongnie, Jean-François ULg; Belluco, Walter

in Moisan, Alphonse; Poulachon, Gérard (Eds.) Proceedings of the 7th CIRP International Workshop on Modeling of Machining Operations (2004, May)

During rough machining operations of powertrain components, chatter vibrations may occur on the edges of flexible structures. This paper presents a numerical method, based on the finite element method and ... [more ▼]

During rough machining operations of powertrain components, chatter vibrations may occur on the edges of flexible structures. This paper presents a numerical method, based on the finite element method and Tlusty's theory, which gives a chatter map of the machined surface. Each map point represents the greatest depth of cut leading to unconditionally stable cut. Each value depends on the structural damping, the cutting stiffness and the local static stiffness, which is computed using conventional linear elastic FEA. Chatter maps offer a convenient and effective decision support system for robust process design. As a case study, the rough milling operation of a crankcase deck face with a two-stage cutter is presented. [less ▲]

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See detailPrise en compte des pressions réparties dans les plaques équilibre
Debongnie, Jean-François ULg

Report (2004)

Equilibrium plate elements are not, in their simplest version, able to take account of a distributed pressure. A particular solution has then to be added. One such solution was develpped by Sander, but is ... [more ▼]

Equilibrium plate elements are not, in their simplest version, able to take account of a distributed pressure. A particular solution has then to be added. One such solution was develpped by Sander, but is only suitable for elements with first degree moments, as it makes use of the side Kirchhoff loads. This paper is devoted to the construction of a particular solution which is equilibrated by corner loads only and, therefore, compatible with the simplest plate element, that is Morley's one [less ▲]

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See detailSur le rang de la matrice de raideur de l'élément de tétraèdre statiqument admissible
Debongnie, Jean-François ULg

Report (2004)

This research concerns the rank of the stiffness matrix of the tetrahedral equilibrium element.

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See detailNew radioiodinated carboxylic and hydroxamic matrix metalloproteinase inhibitor tracers as potential tumor imaging agents
Oltenfreiter, R.; Staelens, L.; Lejeune, Annabelle ULg et al

in Nuclear Medicine & Biology (2004), 31(4), 459-468

Several studies have demonstrated a positive correlation between tumor progression and expression of extracellular proteinases such as matrix metalloproteinases (MMPs). MMP-2 and MMP-9 have become ... [more ▼]

Several studies have demonstrated a positive correlation between tumor progression and expression of extracellular proteinases such as matrix metalloproteinases (MMPs). MMP-2 and MMP-9 have become attractive targets for cancer research because of their increased expression in human malignant tumor tissues of various organs, providing a target for medical imaging techniques. Radioiodinated carboxylic and hydroxamic MMP inhibitors 2-(4'-[123]iodo-biphenyl-4-sulfonylainino)-3-(1H-indol-3-yl)-propionic acid (9) and 2-(4'-[I-123] iodo-biphenyl-4-sulfonylamino)-3-(1H-indol-3-yl)-propionamide (11) were synthesized by electrophilic aromatic substitution of the tributylstannyl derivatives and resulted in radiochemical yields of 60% +/- 5% (n - 3) and 70% +/- 5% (n = 6), respectively. In vitro zymography and enzyme assays showed high inhibition capacities of the inhibitors on gelatinases. In vivo biodistribution showed no long-terin accumulation in organs and the possibility to accumulate in the tumor. These results warrant further studies of radioiodinated carboxylic and hydroxamic MNIP inhibitor tracers as potential SPECT tumor imaging agents. (C) 2004 Elsevier Inc. All rights reserved. [less ▲]

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See detailMontage et gestion budgétaire
Van Caillie, Didier ULg; Marthoz, Cédric

Learning material (2004)

This seminar overviews key elements that are necessary to plan and to budget new projects. An application is realized in the context of an international cooperation project.

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See detailLes émulsifiants dans les produits de boulangerie industrielle : modes d'action, rôles et utilisations.
Delacharlerie, Sophie ULg; Blecker, Christophe ULg; Kegelaers, Yves et al

in Industries Alimentaires et Agricoles (2004), (Mai), 8-14

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See detailRolling and slipping motion of Euler's disk
Caps, Hervé ULg; Dorbolo, Stéphane ULg; Ponte, S. et al

in Physical Review E (2004), 69(5, Pt 2), 56610

We present an experimental study of the motion of a circular disk spun onto a table. With the help of a high speed video system, the temporal evolution of (i) the inclination angle alpha, (ii) the angular ... [more ▼]

We present an experimental study of the motion of a circular disk spun onto a table. With the help of a high speed video system, the temporal evolution of (i) the inclination angle alpha, (ii) the angular velocity omega, and (iii) the precession rate Omega are studied. The influence of the mass of the disk as well as the friction between the disk and the supporting surface are considered. Both inclination angle and angular velocity are observed to decrease according to a power law. We also show that the precession rate diverges as the motion stops. Measurements are performed very near the collapse as well as on long range times. Times to collapse have been also measured. Results are compared with previous theoretical and experimental works. The major source of energy dissipation is found to be the slipping of the disk on the plane. [less ▲]

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