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See detailLa publication électronique en sciences humaines et sociales : des prophéties à la description des usages et des pratiques
Dozo, Björn-Olav ULg; Vachon, Karine

in Mémoires du Livre = Studies in Book Culture (2009), 1(1),

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See detailMaintenance/repair and production-oriented life cycle cost/earning model for ship structural optimization during conceptual design stage
Turan, Osman; Olcer, A. I.; Lazakis, Iraklis et al

in Ships & Offshore Structures (2009), 4(2), 107-125

The aim of this paper is to investigate the effect of the change in structural weight due to optimisation experiments on life cycle cost and earning elements using the life cycle cost/earning model, which ... [more ▼]

The aim of this paper is to investigate the effect of the change in structural weight due to optimisation experiments on life cycle cost and earning elements using the life cycle cost/earning model, which was developed for structure optimisation. The relation between structural variables and relevant cost/earning elements are explored and discussed in detail. The developed model is restricted to the relevant life cycle cost and earning elements, namely production cost, periodic maintenance cost, fuel oil cost, operational earning and dismantling earning. Therefore it is important to emphasise here that the cost/earning figure calculated through the developed methodology will not be a full life cycle cost/earning value for a subject vessel, but will be the relevant life cycle cost/earning value. As one of the main focuses of this paper is the maintenance/repair issue, the data was collected from a number of ship operators and was solely used for the purpose of regression analysis. An illustrative example for a chemical tanker is provided to show the applicability of the proposed approach. [less ▲]

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See detailLivres et architecture : les bibliothèques de l'Université de Liège
Micha, Edith ULg; Oger, Cécile ULg

in Art&Fact (2009), 28

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See detailIn vitro evaluation of the fermentation characteristics in the pig intestines of hulless barleys differing in β-glucan content
Jha, Rajesh; Bindelle, Jérôme ULg; Rossnagel, Brian et al

in Journal of Animal Science (2009), 87(E-Suppl. 3), 103

Non-starch polysaccharides (NSP) in isolated form, especially β-glucans, are reported to have prebiotic effects in pigs. However, little information is available on the possible functional properties of ... [more ▼]

Non-starch polysaccharides (NSP) in isolated form, especially β-glucans, are reported to have prebiotic effects in pigs. However, little information is available on the possible functional properties of these NSP when the latter are still present in the fibrous matrix of whole cereals. Hulless barleys (HB) are good sources of β-glucans and the content is quite variable among varieties. In order to evaluate the potential of HB as functional feeds, an in vitro experiment was carried out to study the fermentation characteristics of 6 HB varieties varying in their β-glucan contents (36-99 g/kg DM) in comparison to 3 hulled barleys and 5 oats. After a pepsin-pancreatin hydrolysis, the ingredients were incubated in a buffer solution containing minerals and pig feces as inoculum. The accumulated gas production, proportional to the amount of fiber fermented, was measured for 48 h and modeled. Short-chain fatty acid (SCFA) and ammonia concentration were measured in the fermented solutions. A cereal type effect (P < 0.05) was observed on the fermentation kinetics parameters. Rates of degradation and total gas productions were higher in HB than in oats (P < 0.05) but no difference was observed between HB varieties. On the contrary, differences were found between HB for lag time and rate of degradation. The production of SCFA was also higher with HB (6.1 mMol/g DM incubated; P < 0.05) than with hulled barleys and oats (4.9 and 2.9 mMol/g DM incubated respectively). In contrast, oats generated higher ammonia (P <0.05) production (1.4 mMol/g DM incubated, on average) than barley (1.0 mMol/g). In conclusion, HB are better fermented in vitro, produce more beneficial (SCFA) and less harmful (ammonia) metabolites and have a better potential than other cereal species to modulate gut microbiota and improve gut health. [less ▲]

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See detailVarietal effects of barley carbohydrate composition on digestibility, fermentability and microbial ecophysiology in an in vitro model of the pig gastrointestinal tract.
Bindelle, Jérôme ULg; Pieper, Robert; Rossnagel, Brian et al

in Journal of Animal Science (2009), 87(E-Suppl. 3), 93

Carbohydrate (CHO) composition can vary markedly between barley varieties. Their influence on digestibility, intestinal fermentation and microbiota in pigs was studied in vitro. Ten hulless (HLB) and 6 ... [more ▼]

Carbohydrate (CHO) composition can vary markedly between barley varieties. Their influence on digestibility, intestinal fermentation and microbiota in pigs was studied in vitro. Ten hulless (HLB) and 6 hulled barleys (HB) differing in B-glucan, non-starch polysaccharides (NSP), starch content, and amylose/amylopectin ratio, were hydrolyzed enzymatically and subsequently fermented for 72h. CHO fermentation kinetics were modeled; microbial composition and short-chain fatty acid (SCFA) production were analyzed. In HLB, in vitro DM digestibility was positively correlated to starch and amylopectin content and CP digestibility to amylopectin (P<0.05), whereas both were negatively correlated to insoluble NSP (P<0.05). Rate of fermentation was different (P<0.01) between barley types but not correlated to the CHO composition. However, high B-glucan contents induced faster fermentation (P<0.05, HLB; P<0.10, HB). SCFA molar ratios after fermentation of HLB were higher in propionate and branchedchain fatty acids and lower in acetate compared to HB (P<0.01). With HLB, amylose content was positively correlated to butyrate production and negatively to propionate, which was positively correlated to soluble NSP content (P<0.01). In HB, no correlation between SCFA production and the carbohydrate composition was found. TRFLP analysis revealed that Bacteroides and members of Clostridium cluster XIVa were differentially affected in HLB compared to HB as well as by the type and source of CHO. Microbial profiles were also correlated (P<0.05) to SCFA and fermentation parameters but response differed significantly between HB and HLB. The strongest correlation between CHO structure, microbial abundance and fermentation parameters was evident in HLB. Hulless barleys may offer the greatest opportunity to improve gut health in pigs. [less ▲]

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See detailComputational Hemodynamics Coupled with Mechanical Behaviour of the Surrounded Materials, in the Specific Case of the Brachial Artery
Paulus, Raphaël ULg; Erpicum, Sébastien ULg; Dewals, Benjamin ULg et al

in Proceedings of Biomed 2009 - Eighth International Conference on Modelling in Medicine and Biology (2009)

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See detailDetection and Correction of Outliers for Fatty Acids Contents Measured by Mid-Infrared Spectrometry Using Random Regression Test-Day Models
Soyeurt, Hélène ULg; Dardenne, Pierre; Gengler, Nicolas ULg

in Book of Abstracts of the 60th Annual Meeting of the European Association for Animal Production (2009)

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See detailA prospective randomized multicenter trial of darbepoetin-alfa and I.V. iron administration after autologous hematopoietic stem cell transplantation.
Beguin, Yves ULg; Maertens, J.; DE PRIJCK, Bernard ULg et al

Poster (2009)

We conducted a multicenter prospective randomized study analyzing the impact of darbepoetin alfa (DA) with or mithout i.v. iron on erythroid recovery after autologous HCT.

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See detail« Les imaginaires des migrants lesbiennes et gays latino-américains à propos de l’Europe. Analyse de récits de vie de chilien(ne)s, péruvien(ne)s et colombiens »
Berlage, Pauline ULg

in Sophia (Ed.) Colloque 20 ans de Sophia « Savoir de genre : quels genres de savoir ? Etats des lieux des études de genre (2009)

Cette communication traite d’une population peu souvent prise en compte dans les études migratoires en Europe jusqu'au jour d’aujourd’hui, il s’agit des migrants lesbiennes et gays latino-américains en ... [more ▼]

Cette communication traite d’une population peu souvent prise en compte dans les études migratoires en Europe jusqu'au jour d’aujourd’hui, il s’agit des migrants lesbiennes et gays latino-américains en Europe et nous traiterons ici plus particulièrement des imaginaires de ces migrants. Cette présentation sera divisée en trois parties : nous préciserons d’abord quelle a été la question de départ de cette recherche et les hypothèses posées. Ensuite nous exposerons quels ont été les imaginaires à propos de l’Europe les plus prégnants, c'est-à-dire, ceux qui se sont répétés dans les différents récits de vie. Nous conclurons enfin en analysant plus globalement la dialectique, l’évolution et les associations des imaginaires discutés. [less ▲]

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See detailActivation and coagulation biomarkers are independent predictors of the development of opportunistic disease in patients with HIV infection.
Rodger, Alison J; Fox, Zoe; Lundgren, Jens D et al

in Journal of Infectious Diseases (2009), 200(6), 973-83

BACKGROUND: Activation and coagulation biomarkers were measured within the Strategies for Management of Antiretroviral Therapy (SMART) trial. Their associations with opportunistic disease (OD) in human ... [more ▼]

BACKGROUND: Activation and coagulation biomarkers were measured within the Strategies for Management of Antiretroviral Therapy (SMART) trial. Their associations with opportunistic disease (OD) in human immunodeficiency virus (HIV)-positive patients were examined. METHODS: Inflammatory (high-sensitivity C-reactive protein [hsCRP], interleukin-6 [IL-6], amyloid-A, and amyloid-P) and coagulation (D-dimer and prothrombin-fragment 1+2) markers were determined. Conditional logistic regression analyses were used to assess associations between these biomarkers and risk of OD. RESULTS: The 91 patients who developed an OD were matched to 182 control subjects. Patients with an hsCRP level > or =5 microg/mL at baseline had a 3.5 higher odds of OD (95% confidence interval [CI], 1.5-8.1) than did those with an hsCRP level <1 microg/mL (P=.003, by test for trend) and patients with an IL-6 level > or =3 pg/mL at baseline had a 2.4 higher odds of OD (95% CI, 1.0-5.4) than did those with an IL-6 level <1.5 pg/mL (P=.02, by test for trend). No other baseline biomarkers predicted development of an OD. Latest follow-up hsCRP level for those with an hsCRP level > or =5 microg/mL (compared with a level <1 microg/mL; odds ratio [OR], 7.6; 95% CI, 2.0-28.5; [P=.002, by test for trend), latest amyloid-A level for those with an amyloid-A level > or =6 mg/L (compared with a level <2 mg/L; OR, 3.8; 95% CI, 1.1-13.4; P=.03, by test for trend), and latest IL-6 level for those with an IL-6 level > or =3 pg/mL (compared with a level <1.5 pg/mL; OR 2.4; 95% CI, 0.7-8.8; P=.04, by test for trend) were also associated with development of an OD. CONCLUSIONS: Higher IL-6 and hsCRP levels independently predicted development of OD. These biomarkers could provide additional prognostic information for predicting the risk of OD. [less ▲]

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See detailInhibition of the Jagged-1/Notch pathway increases the hematopoiesis-supportive activity of mesenchymal stem cells
Briquet, Alexandra ULg; Dolhet, Marie; Beguin, Yves ULg et al

in Experimental Hematology (2009), 37(9), 77

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See detailNeología semántica y polisemia: el caso del truncamiento
Steffens, Marie ULg; Baiwir, Esther ULg

in Revista de Investigación Lingüística (2009), 12

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See detailL’impact de l’exposition à des modèles d’entrepreneurs sur les antécédents de l’intention entrepreneuriale
Aouni, Zineb ULg; Pirnay, Fabrice ULg

in Actes du 6ème Congrès de l’Académie de L’Entrepreneuriat (2009)

Devant la multiplication des programmes de formation et de sensibilisation à l’entrepreneuriat, la question reste posée quant à l’efficacité des actions et des méthodes pédagogiques utilisées. La présente ... [more ▼]

Devant la multiplication des programmes de formation et de sensibilisation à l’entrepreneuriat, la question reste posée quant à l’efficacité des actions et des méthodes pédagogiques utilisées. La présente étude propose de à cette question en s’intéressant à l’impact d’un événement de sensibilisation de courte durée (une soirée) qui utilise prioritairement une seule méthode pédagogique consistant en l’exposition à des modèles d’entrepreneurs. L’évaluation d’impact se base sur des indicateurs liés aux changements d’attitudes à l’égard de l’entrepreneuriat et par conséquent à des changements au niveau de l’intention d’entreprendre. Se basant sur la théorie de l’apprentissage entrepreneurial qui suppose que les individus apprennent différemment d’une même expérience en fonction de leur niveau de connaissance initial (Minniti et Bygrave, 2001 ; Cope, 2005), cette étude distingue l’analyse d’impact selon deux groupes de participants en fonction de leur niveau de perceptions (attitudes et sentiment de capacité) et d’intention entrepreneuriale initial. Les résultats de cette étude permettent ainsi d’identifier les variables de perception pouvant influencer l’impact de l’exposition à des modèles d’entrepreneurs et de conclure par rapport à l’influence du stock de connaissances préalable sur le processus d’apprentissage entrepreneurial. La méthode préconisée propose une analyse comparative entre un échantillon de 288 participants à l’événement de sensibilisation et un groupe de contrôle composé de 46 répondants non participants. La présente étude repose ainsi sur le protocole pré-post test avec groupe de contrôle. En terme d’implications pratiques, cette étude permet aux responsables de formations à l’entrepreneuriat d’appliquer des méthodes pédagogiques appropriées au public auquel ils s’adressent (en terme de niveau de perceptions et d’intention entrepreneuriale) ou de mieux cibler le public approprié aux actions pédagogiques utilisées. [less ▲]

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See detail“Les imaginaires des migrants lesbiennes et gays latino-américains à propos de l’Europe: perspectives ethnographiques à partir du travail de terrain à Santiago (Chili)”
Berlage, Pauline ULg

in Yépez del Castillo, Isabel; Charlier, Sophie; Grenade, Sophie (Eds.) Les recherches en « genre et développement » pour des politiques de développement appropriées (2009)

Cette contribution a comme objectif de visibiliser une question peu souvent prise en compte en Europe jusqu’au jour d’aujourd’hui, il s’agit des migrations des lesbiennes et gays latino-américains en ... [more ▼]

Cette contribution a comme objectif de visibiliser une question peu souvent prise en compte en Europe jusqu’au jour d’aujourd’hui, il s’agit des migrations des lesbiennes et gays latino-américains en Europe. Ce travail se concentre plus particulièrement sur des migrants d’origine chilienne, péruvienne et colombienne et veut comprendre les imaginaires 86 à propos de l’Europe de ces migrants lesbiennes et gays. Cette recherche, toujours en cours, implique des travaux de terrain (entretiens et observations) réalisés en Belgique, en Espagne (Madrid et Salamanca) et au Chili (Santiago). La présentation de cette recherche se centrera sur le travail de terrain réalisé à Santiago. [less ▲]

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See detailStructure of PBP-A from Thermosynechococcus elongatus, a Penicillin-Binding Protein Closely Related to Class A β-Lactamases
Urbach, Carole; Evrard, Christine ULg; Pudzaitis, Vaidas et al

in Journal of Molecular Biology (2009), 386

Molecular evolution has always been a subject of discussions, and researchers are interested in understanding how proteins with similar scaffolds can catalyze different reactions. In the superfamily of ... [more ▼]

Molecular evolution has always been a subject of discussions, and researchers are interested in understanding how proteins with similar scaffolds can catalyze different reactions. In the superfamily of serine penicillin-recognizing enzymes, D-alanyl-D-alanine peptidases and β-lactamases are phylogenetically linked but feature large differences of reactivity towards their respective substrates. In particular, while β-lactamases hydrolyze penicillins very fast, leading to their inactivation, these molecules inhibit D-alanyl-D-alanine peptidases by forming stable covalent penicilloyl enzymes. In cyanobacteria, we have discovered a new family of penicillin-binding proteins (PBPs) presenting all the sequence features of class A β-lactamases but having a six-amino-acid deletion in the conserved Ω-loop and lacking the essential Glu166 known to be involved in the penicillin hydrolysis mechanism. With the aim of evolving a member of this family into a β-lactamase, PBP-A from Thermosynechococcus elongatus has been chosen because of its thermostability. Based on sequence alignments, introduction of a glutamate in position 158 of the shorter Ω-loop afforded an enzyme with a 50-fold increase in the rate of penicillin hydrolysis. The crystal structures of PBP-A in the free and penicilloylated forms at 1.9 Å resolution and of L158E mutant at 1.5 Å resolution were also solved, giving insights in the catalytic mechanism of the proteins. Since all the active-site elements of PBP-A-L158E, including an essential water molecule, are almost perfectly superimposed with those of a class A β-lactamase such as TEM-1, the question why our mutant is still 5 orders of magnitude less active as a penicillinase remains and our results emphasize how far we are from understanding the secrets of enzymes. Based on the few minor differences between the active sites of PBP-A and TEM-1,mutations were introduced in the L158E enzyme, but while activities on D-Ala-D-Ala mimicking substrates were severely impaired, further improvement in penicillinase activity was unsuccessful. [less ▲]

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See detailLes indicateurs d'inclusion sociale. Où est la Wallonie aujourd'hui?
Atta, Cécile; Maréchal, Claire; Perelman, Sergio ULg

in Thys, F.; Dejardin, M. (Eds.) Wallonie et Bruxelles: analyses et enjeux (2009)

We use the primary indicators of social inclusion proposed within the scope of the Open Method of Coordination (OMC) to situate Wallonia in the European Union (EU15) context. The results show that ... [more ▼]

We use the primary indicators of social inclusion proposed within the scope of the Open Method of Coordination (OMC) to situate Wallonia in the European Union (EU15) context. The results show that Wallonia stood in 2005 at the same level as Greece and was behind the EU15 level mainly regarding poverty and long-term unemployment rates. Groups at risk are single-parent families as well as unemployed and other inactive categories. Having at disposal these indicators for the years to come will be a must not only for the design but also for the evaluation of policies towards a better social cohesion. [less ▲]

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See detailLe commerce sensible des biens à double usage : analyses des législations européennes et des États-Unis
Rasson, Frédéric ULg

Master's dissertation (2009)

L’Union européenne a réglementé le commerce sensible des biens et technologies à double usage. Quelles différences existent entre le système harmonisé européen de contrôle sur les exportations d’articles ... [more ▼]

L’Union européenne a réglementé le commerce sensible des biens et technologies à double usage. Quelles différences existent entre le système harmonisé européen de contrôle sur les exportations d’articles à double usage et le contrôle organisé par les États-Unis ? [less ▲]

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