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See detailGeneva photometry of HD 129929 (Aerts+, 2004)
Aerts, C.; Waelkens, C.; Daszynska-Daszkiewicz, J. et al

in SIMBAD (2003), 341

We have gathered and analysed a timeseries of 1493 high-quality multicolour Geneva photometric data of the B3V {beta} Cep star Hd 129929. The dataset has a time base of 21.2 years. The occurrence of a ... [more ▼]

We have gathered and analysed a timeseries of 1493 high-quality multicolour Geneva photometric data of the B3V {beta} Cep star Hd 129929. The dataset has a time base of 21.2 years. The occurrence of a beating phenomenon is evident from the data. We find evidence for the presence of at least six frequencies, among which we see components of two frequency multiplets with an average spacing of ~0.0121c/d which points towards very slow rotation. This result is in agreement with new spectroscopic data of the star and also with previously taken UV spectra. We provide the amplitudes of the six frequencies in all seven photometric filters. The metal content of the star is Z=0.018+/-0.004. All these observational results will be used to perform detailed seismic modelling of this massive star in a subsequent paper. (1 data file). [less ▲]

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See detailOptical and mechanical design of a straylight rejection baffle for CoRoT
Plesseria, Jean-Yves ULg; Mazy, Emmanuel ULg; Defise, Jean-Marc ULg et al

in Society of Photo-Optical Instrumentation Engineers (SPIE) Conference Series (2003, November 01)

The COROT mission is part of the program "Petites Missions" of CNES (French space agency). It implies international cooperation between France, Belgium, Germany, Austria, Spain and the European Space ... [more ▼]

The COROT mission is part of the program "Petites Missions" of CNES (French space agency). It implies international cooperation between France, Belgium, Germany, Austria, Spain and the European Space Agency (ESA). COROT aims to perform astroseismology measurements and to detect exoplanets. Long duration observations of stars will be used to detect periodic variations with an afocal telescope followed by a dioptric objective and 4 CCDs. Due to the orbit of the spacecraft (low altitude polar orbit) and even if the observation are performed in a direction perpendicular to orbit plane, the measurements can be disturbed by the straylight reflected on the earth (albedo) that can generate periodic perturbation. CSL is in charge of the design and procurement, with the help of Belgian industries, of a baffle and its protective cover that will be mounted on top of the afocal entrance telescope. The requirements are very stringent from the optical point of view as well as from the mechanical point of view. The rejection of the baffle must be of the order of 10[SUP]13[/SUP] for field angles above 20 degrees while the allocated mass is 19 kilograms. [less ▲]

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See detailSimulated annealing for complex portfolio selection problems
Crama, Yves ULg; Schyns, Michael ULg

in European Journal of Operational Research (2003), 150(3), 546-571

This paper describes the application of a simulated annealing approach to the solution of a complex portfolio selection model. The model is a mixed integer quadratic programming problem which arises when ... [more ▼]

This paper describes the application of a simulated annealing approach to the solution of a complex portfolio selection model. The model is a mixed integer quadratic programming problem which arises when Markowitz' classical mean-variance model is enriched with additional realistic constraints. Exact optimization algorithms run into difficulties in this framework and this motivates the investigation of heuristic techniques. Computational experiments indicate that the approach is promising for this class of problems. (C) 2003 Elsevier B.V. All rights reserved. [less ▲]

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See detailPharmacodynamics of follicle stimulating hormone (FSH) in postmenopausal women during pulsed estrogen therapy: Evidence that FSH release and synthesis are controlled by distinct pathways
Christin-Maitre, S.; Laveille, C.; Collette, Julien ULg et al

in Journal of Clinical Endocrinology and Metabolism (2003), 88(11), 5405-5413

17beta-Estradiol (E2) exerts negative feedback effects at the hypothalamo-pituitary level on serum FSH. This study investigated the effects of repeated daily administration of intranasal E2 (S21400) on ... [more ▼]

17beta-Estradiol (E2) exerts negative feedback effects at the hypothalamo-pituitary level on serum FSH. This study investigated the effects of repeated daily administration of intranasal E2 (S21400) on the pharmacokinetics (PK) of E2 and estrone (E1) and the pharmacodynamics (PD) of FSH and assessed the PK/PD relationship between E2 and FSH using population model-dependent analysis. Postmenopausal volunteers (n = 24) received according to a balanced cross-over design, two 28-d treatments separated by a 2-month wash-out period: 300 mug E2, either alone or combined with oral dydrogesterone (20 mg/d) during the last 14 d of one of the treatments. Absorption of E2 was rapid, with maximal plasma concentrations at 10-30 min, returning to postmenopausal levels within 12 h. Over the 24-h period, FSH levels showed a U curve, with a minimum around 8 h after E2 administration. Moreover, over the treatment period, FSH basal values decreased by 17% between d 1 and 14 and an additional 5% between d 14 and 28. A PK/PD model described these short- and mid-term effects, possibly reflecting separate regulation mechanisms by E2 on FSH release and biosynthesis, respectively. The administration of progestin had no influence on E1, E2, and FSH model parameters. This study suggests that daily transient tissue exposure to E2 after pulsed estrogen therapy elicits short- and mid-term effects on the gonadotropin axis. [less ▲]

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See detailOverexpression of the soluble vascular endothelial growth factor receptor in preeclamptic patients: Pathophysiological consequences
Tsatsaris, V.; Goffin, Frédéric ULg; Munaut, Carine ULg et al

in Journal of Clinical Endocrinology and Metabolism (2003), 88(11), 5555-5563

Several growth factors such as vascular endothelial growth factor (VEGF)-A and placental growth factor (PlGF) are involved in the placental vascular development. We investigated whether dysregulation in ... [more ▼]

Several growth factors such as vascular endothelial growth factor (VEGF)-A and placental growth factor (PlGF) are involved in the placental vascular development. We investigated whether dysregulation in the VEGF family may explain the defective uteroplacental vascularization characterizing preeclampsia. We compared pregnancies complicated by early onset severe preeclampsia or intrauterine growth retardation to normal pregnancies. Maternal plasma, placentas, and placental bed biopsies were collected. The mRNA levels of VEGF-A, PlGF, and their receptors were quantified in placentas and placental beds. Levels of VEGF-A, PlGF, and soluble VEGF receptor (VEGFR) were assessed in maternal plasma. In compromised pregnancies, elevated levels of VEGF-A and VEGFR-1 mRNAs may reflect the hypoxic status of the placenta. On contrast, the membrane-bound VEGFR-1 was decreased in the placental bed of preeclamptic patients. Preeclampsia was associated with low levels of circulating PlGF and increased levels of total VEGF-A and soluble VEGFR-1. Free VEGF-A was undetectable in maternal blood. Immunohistochemical studies revealed that VEGF-A and PlGF were localized in trophoblastic cells. Altogether, our results suggest two different pathophysiological mechanisms associated with preeclampsia. The first one is related to an overproduction of competitive soluble VEGFR-1 that may lead to suppression of VEGF-A and PlGF effects. The second one is the down-regulation of its membrane bound form (VEGFR-1) in the placental bed, which may result in the defective uteroplacental development. [less ▲]

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See detailRemote sensing of the proton aurora characteristics from IMAGE-FUV
Bisikalo, D. V.; Shematovich, V. I.; Gérard, Jean-Claude ULg et al

in Annales Geophysicae [= ANGEO] (2003), 21

The combination of simultaneous global images of the north polar region obtained with the IMAGE-FUV imaging system makes it possible to globally map the properties of the electron and proton auroral ... [more ▼]

The combination of simultaneous global images of the north polar region obtained with the IMAGE-FUV imaging system makes it possible to globally map the properties of the electron and proton auroral precipitation. The SI12 imager, which observes the Doppler-shifted Lyman-a [less ▲]

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See detailCompléments de C++
Boman, Romain ULg

Scientific conference (2003, November)

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See detailAcquired aqueductal stenosis in preterm infants: an indication for neuroendoscopic third ventriculostomy
Scavarda, D; Bednarek, N; Litré, Claude Fabien ULg et al

in Child's Nervous System (2003), 19(10-11), 756-9

Abstract Object: The object of this study is to demonstrate the delayed occurrence of aqueductal stenosis in preterm infants who have suffered from intraventricular hemorrhage (IVH) and to try to explain ... [more ▼]

Abstract Object: The object of this study is to demonstrate the delayed occurrence of aqueductal stenosis in preterm infants who have suffered from intraventricular hemorrhage (IVH) and to try to explain the mechanisms of this stenosis. Method: From January 1996 to June 2002, 1,046 premature infants were admitted to our institution. Thirty-six neonates suffered from grade 3 or 4 intraventricular hemorrhage (Papile grading), of whom 16 died. Twenty patients survived and a ventriculoperitoneal shunt was inserted in 7 infants. Four patients underwent a neuroendoscopic third ventriculostomy. Follow-up was carried out, twice a month during the first 2 months and subsequently twice a year. Conclusion: In 2 children NTV was an effective treatment for hydrocephalus with an average follow-up of 29 months. The specific pattern concerning these patients is the long delay before obstructive hydrocephalus and the visualization of de novo obstruction with MRI. The biological explanation must be investigated. Keywords Premature newborn · Intraventricular hemorrhage · Hydrocephalus · Neuroendoscopy · Aqueductal stenosis · Acquired obstructive hydrocephalus · Transforming growth factor b1 [less ▲]

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See detailUn bilan du programme quinquennal 1998-2002
Lonfils, R.; Lebailly, D.; De Bock, C. et al

in Education Santé (2003), (184), 10-16

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See detailNotions d'acoustique
Embrechts, Jean-Jacques ULg

Conference (2003, November)

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See detailRole of estrogens in the modulation of inflammatory pain : a study in aromatase knock-out mice using the trigeminal formalin model
Multon, Sylvie ULg; RIKIR, Estelle ULg; HALLEUX, Sandrine ULg et al

in Book of Abstracts of the 33th Annual Meeting Society for Neuroscience (Nov 2003) (2003, November)

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See detailActivation of circulating polymorphonuclear neutrophils during exercise-induced muscle damage
Camus, Gérard; Croisier, Jean-Louis ULg; Chapelle, Jean-Paul ULg et al

in Pflugers Arch – Eur J Physiol (2003, November), 447

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See detailL'image du mois. Une varice duodenale compliquant une hypertension portale
Detry, Olivier ULg; Delwaide, Jean ULg; De Roover, Arnaud ULg et al

in Revue Médicale de Liège (2003), 58(11), 657-8

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See detailOMC: An Optical Monitoring Camera for INTEGRAL - Instrument description and performance
Mas-Hesse, J. M.; Gimenez, A.; Culhane, J. L. et al

in Astronomy and Astrophysics (2003), 411(1), 261-268

The Optical Monitoring Camera (OMC) will observe the optical emission from the prime targets of the gammaray instruments onboard the ESA mission INTEGRAL, with the support of the JEM-X monitor in the X ... [more ▼]

The Optical Monitoring Camera (OMC) will observe the optical emission from the prime targets of the gammaray instruments onboard the ESA mission INTEGRAL, with the support of the JEM-X monitor in the X-ray domain. This capability will provide invaluable diagnostic information on the nature and the physics of the sources over a broad wavelength range. Its main scientific objectives are: ( 1) to monitor the optical emission from the sources observed by the gamma- and X-ray instruments, measuring the time and intensity structure of the optical emission for comparison with variability at high energies, and ( 2) to provide the brightness and position of the optical counterpart of any gamma- or X-ray transient taking place within its field of view. The OMC is based on a refractive optics with an aperture of 50 mm focused onto a large format CCD (1024 x 2048 pixels) working in frame transfer mode (1024 x 1024 pixels imaging area). With a field of view of 5degrees x 5degrees it will be able to monitor sources down to magnitude V = 18. Typical observations will perform a sequence of different integration times, allowing for photometric uncertainties below 0.1 mag for objects with V less than or equal to 16. [less ▲]

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See detailManagement of Electric and Hybrid vehicles
Lilien, Jean-Louis ULg; Yuan, H.

(2003, November)

The battery management system (BMS) is an important feature for electric (EVs) and hybrid (HVs) vehicles. The BMS has close connections with the vehicle control and command and gives access to real time ... [more ▼]

The battery management system (BMS) is an important feature for electric (EVs) and hybrid (HVs) vehicles. The BMS has close connections with the vehicle control and command and gives access to real time power available and remaining autonomy. Such information is dramatic and comprises major inputs of the hybrid vehicle strategy on the road. The BMS is obviously related to battery modeling. Electrochemical modeling would be based on the qualification of the intrinsic chemical reactions and would help to define the parameters of the battery. Generally it is hopeless to use this model in such applications, due to all its complexities [less ▲]

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See detailThe use of mycophenolate mofetil in liver transplant recipients
Detry, Olivier ULg; De Roover, Arnaud ULg; Delwaide, Jean ULg et al

in Expert Opinion on Pharmacotherapy (2003), 4(11), 1949-1957

Mycophenolate mofetil is an important drug in the modern immunosuppressive arsenal. Mycophenolate mofetil is the semisynthetic morpholinoethyl ester of mycophenolate acid. Mycophenolate acid prevents T ... [more ▼]

Mycophenolate mofetil is an important drug in the modern immunosuppressive arsenal. Mycophenolate mofetil is the semisynthetic morpholinoethyl ester of mycophenolate acid. Mycophenolate acid prevents T and B cell proliferation by specifically inhibiting a purine pathway required for lymphocyte division. This paper extensively reviews the experience of mycophenolate mofetil use in liver transplant recipients. In randomised trials, mycophenolate mofetil decreased the rate of acute rejection after liver transplantation, without a significant increase of septic complications. However, so far, there are no data indicating that mycophenolate mofetil increases liver transplant patient or graft survivals. Mycophenolate mofetil is interesting because of its particular side effects profile, which is very different from the other immunosuppressants. The absence of mycophenolate mofetil nephrotoxicity is of specific interest in liver recipients with impairment of renal function. The monitoring of mycophenolate acid area under the concentration time curve might be interesting to limit side effects and provide better clinical efficacy but the exact role of mycophenolate acid monitoring in liver recipients has yet to be further evaluated in large series. [less ▲]

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See detailLe livre de l'ânesse de Balaam, de David Jones, Traduction, notes et introduction critique
Pagnoulle, Christine ULg; Pagnoulle, Christine ULg

Book published by Editions associatives Clapas (2003)

The poetic sequence called 'The book of Balaam's Ass' was only published after David Jones's death. It is indeed riddled with contradictions and inconsistencies, but of the kind that can hardly be ... [more ▼]

The poetic sequence called 'The book of Balaam's Ass' was only published after David Jones's death. It is indeed riddled with contradictions and inconsistencies, but of the kind that can hardly be overcome. In a nutshell it is about the loss of grace, both in the later stage of the Great War (from the Somme offensive onwards) and in a postwar world in which the author feels all sense of the holy has been erased. [less ▲]

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See detailThe practice of muscles infiltration of botulinic toxin in spasticity
Battisti, Oreste ULg

Learning material (2003)

this video shows the practice of multilevels injection in muscles of botulinic toxin in the tretament of spasticity i children, with a particular focus of the iloi-psoas injection sites.

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See detailEgr family members regulate nonlymphoid expression of Fas ligand, TRAIL, and tumor necrosis factor during immune responses.
Droin, Nathalie; Pinkoski, Mike; Dejardin, Emmanuel ULg et al

in Molecular & Cellular Biology (2003), 23(21), 7638-7647

The Fas ligand (FasL)/Fas pathway is crucial for homeostasis of the immune system and peripheral tolerance. Peripheral lymphocyte deletion involves FasL/Fas in at least two ways: coexpression of both Fas ... [more ▼]

The Fas ligand (FasL)/Fas pathway is crucial for homeostasis of the immune system and peripheral tolerance. Peripheral lymphocyte deletion involves FasL/Fas in at least two ways: coexpression of both Fas and its ligand on T cells, leading to activation-induced cell death, and expression of FasL by nonlymphoid cells, such as intestinal epithelial cells (IEC), that kill Fas-positive T cells. We demonstrate here that superantigen Staphylococcus enterotoxin B (SEB) induced a dramatic upregulation of FasL, TRAIL, and TNF mRNA expression and function in IEC from BALB/c and C57BL/6 mice. Using adoptive transfer in which CD4(+) T cells from OT-2 T-cell receptor transgenic mice were transferred into recipients, we observed an induction in IEC of FasL, TRAIL, and TNF mRNA after administration of antigen. Specific Egr-binding sites have been identified in the 5' promoter region of the FasL gene, and Egr-1, Egr-2, and Egr-3 mRNA in IEC from mice treated with SEB and from transgenic OT-2 mice after administration of antigen was upregulated. Overexpression of Egr-2 and Egr-3 induced endogenous ligand upregulation that was inhibited by overexpression of Egr-specific inhibitor Nab1. These results support a role for Egr family members in nonlymphoid expression of FasL, TRAIL, and TNF. [less ▲]

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