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See detailMnasistratos, the hierophant at Andania (IG 5.1.1390 and Syll.³ 735)
Pirenne-Delforge, Vinciane ULg

in Kuiper, Yme B.; Dijkstra, Jitse H.F.; Kroesen, Justin E.A. (Eds.) Myths, Martyrs and Modernity – Studies in the History of Religion in Honor of Jan N. Bremmer (2010)

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See detailA Meta Model to Optimal Design the VSI T2 Chart
Faraz, Alireza ULg; Heuchenne, Cédric ULg; Saniga, E.

Report (2010)

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See detailExhaled nitric oxide thresholds associated with a sputum eosinophil count >=3% in a cohort of unselected patients with asthma.
Schleich, FLorence ULg; Seidel, Laurence ULg; Sele, Jocelyne ULg et al

in Thorax (2010), 65(12), 1039-1044

Background It has been claimed that exhaled nitric oxide (FeNO) could be regarded as a surrogate marker for sputum eosinophil count in patients with asthma. However, the FeNO threshold value that ... [more ▼]

Background It has been claimed that exhaled nitric oxide (FeNO) could be regarded as a surrogate marker for sputum eosinophil count in patients with asthma. However, the FeNO threshold value that identifies a sputum eosinophil count >/=3% in an unselected population of patients with asthma has been poorly studied. Methods This retrospective study was conducted in 295 patients with asthma aged 15-84 years recruited from the asthma clinic of University Hospital of Liege. Receiver-operating characteristic (ROC) curve and logistic regression analysis were used to assess the relationship between sputum eosinophil count and FeNO, taking into account covariates such as inhaled corticosteroids (ICS), smoking, atopy, age and sex. Results Derived from the ROC curve, FeNO >/=41 ppb gave 65% sensitivity and 79% specificity (AUC=0.777, p=0.0001) for identifying a sputum eosinophil count >/=3%. Using logistic regression analysis, a threshold of 42 ppb was found to discriminate between eosinophilic and non-eosinophilic asthma (p<0.0001). Patients receiving high doses of ICS (>/=1000 mug beclometasone) had a significantly lower FeNO threshold (27 ppb) than the rest of the group (48 ppb, p<0.05). Atopy also significantly altered the threshold (49 ppb for atopic vs 30 ppb for non-atopic patients, p<0.05) and there was a trend for a lower threshold in smokers (27 ppb) compared with non-smokers (46 ppb, p=0.066). Age and sex did not affect the relationship between FeNO and sputum eosinophilia. When combining all variables into the logistic model, FeNO (p<0.0001), high-dose ICS (p<0.05) and smoking (p<0.05) were independent predictors of sputum eosinophilia, while there was a trend for atopy (p=0.086). Conclusion FeNO is able to identify a sputum eosinophil count >/=3% with reasonable accuracy and thresholds which vary according to dose of ICS, smoking and atopy. [less ▲]

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See detailPrescribed regimen is effective.
Reginster, Jean-Yves ULg; Altman, Roy D; Hochberg, Marc C

in BMJ (Clinical Research ed.) (2010), 341

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See detailLa modernisation de la Justice comme pédagogie du changement: le cas de l'intégration de "conseillers en ressources humaines" dans les juridictions belges.
Ficet, Joël ULg; Delvaux, David ULg

in Politiques et management public (2010), 27(2), 55-73

Les tribunaux belges viennent de connaître une double mutation: la dépolitisation de la magistrature d'une part, l'amélioration de l'efficience du service public d'autre part. Parmi l'arsenal des moyens ... [more ▼]

Les tribunaux belges viennent de connaître une double mutation: la dépolitisation de la magistrature d'une part, l'amélioration de l'efficience du service public d'autre part. Parmi l'arsenal des moyens mis en ouvre, l'article s'attachera à analyser une des mesures: l'insertion à titre expérimental de "conseillers en gestion des ressources humaines" dont l'objectif principal est de réduire progressivement le délai de traitement des affaires. Mais l'impact de l'introduction de ce nouveau corps semble très marginal quant à son objectif officiel. En revanche, cet élément de réforme a contribué à un changement de nature cognitive, ouvrant la voie à une appropriation des méthodes managériales par les acteurs du monde judiciaire grâce au nouveau cadre de délibération qu'il a permis d'introduire. [less ▲]

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See detailPoésie et sphère publique au tournant des XIXe et XXe siècles : le cas du Figaro
Durand, Pascal ULg

in Blandin, Claire (Ed.) Le Figaro. Histoire d'un journal (2010)

Le Figaro a été l'un des lieux d'articulation et d'affrontement entre modernité littéraire et sphère publique. Baudelaire y publie sa grande étude sur "Le peintre de la vie moderne", Mallarmé y lance son ... [more ▼]

Le Figaro a été l'un des lieux d'articulation et d'affrontement entre modernité littéraire et sphère publique. Baudelaire y publie sa grande étude sur "Le peintre de la vie moderne", Mallarmé y lance son projet de réforme du Domaine public. Jean Moréas surtout y publie son article de lancement de "L'école symbolique", premier manifeste littéraire au sens strict, en attendant la parution, dans les mêmes colonnes, du "Manifeste du futurisme" de Marinetti. Apogée terminale de la modernité, d'un côté. Lancement fracassant des avant-gardes, de l'autre. [less ▲]

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See detailIncreased mitosis in the bleached gastrodermis of the sea anemone A. pallida
Fransolet, David ULg; Roberty, Stéphane ULg; Plumier, Jean-Christophe ULg

Poster (2010)

Today, coral bleaching represents a major concern for marine biologists, especially considering the upsurge of this phenomenon possibly linked to climate change. Bleached corals, deprived of most of their ... [more ▼]

Today, coral bleaching represents a major concern for marine biologists, especially considering the upsurge of this phenomenon possibly linked to climate change. Bleached corals, deprived of most of their energy incomes, may show a partial or total mortality, which ultimately lead to shifts in reef communities. Studies focusing on cellular bleaching mechanisms have shown different ways by which algae may be expelled from gastrodermal host cells. Among those mechanisms, major emphasis has been put on host cell death, most probably due to both apoptosis and necrosis. Recovering gastrodermis is then expected to undergo regeneration process in order to be reinfected by new algae. We describe here this regeneration process in the bleached sea anemone model A. pallida. [less ▲]

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See detailConvective drying of gels: comparison between simulated and experimental moisture profiles obtained by X-ray microtomography
Escalona, Ivonne; Jomaa, Wahbi; Olivera-Fuentes, C. et al

in Drying Technology (2010), 28(5), 644-650

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See detailPhotoacclimation responses of a symbiotic sea anemone reveal an important host cellular plasticity
Roberty, Stéphane ULg; Fransolet, David ULg; Ladrière, Ophélie ULg et al

Poster (2010)

The high productivity of coral reef ecosystems is largely attributed to the mutualistic symbiosis between reef-building corals and their intracellular dinoflagellate in the genus Symbiodinium commonly ... [more ▼]

The high productivity of coral reef ecosystems is largely attributed to the mutualistic symbiosis between reef-building corals and their intracellular dinoflagellate in the genus Symbiodinium commonly referred to as zooxanthellae. These photosynthetic algae translocate a majority of their photosynthetically fixed carbon to the host and contribute to their metabolic needs and the calcification process. <i>Symbiodinium</i> must maintain a balance between the energy derived from the light reactions in the chloroplast and the amount of energy used during dark reactions and other metabolic processes. Nevertheless, in the natural environment the holobiont have to cope with daily and seasonal changes in light intensity, upsetting that balance and creating a stress that induces a physiological response (photoacclimation) to optimize growth rates. After a ten day exposition to high and very low light intensity, morphological and photophysiological analysis conducted on the symbiotic sea anemone, Anemonia manjano, reveal significant modifications of the host tissues ultrastructure and the Symbiodinium metabolic processes (photosynthesis, respiration). Those results highlight particularly important gastrodermal and ectodermal plasticity in which symbiotic cnidarians acclimate to the Symbiodinium physiological status (mainly photosynthesis) by varying the density of particular cellular types (e.g.: cnidocytes, gastrodermal cells) contained in their tissues. [less ▲]

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See detailSYMBIODINIUM SP. CAN STAY ALIVE THROUGH THE GUT AND IN THE FAECES OF CNIDARIA. PREDATORS. THE CASE OF CORALLIOPHILLA MEYENDORFFI AND ANEMONIA VIRIDIS.
Poulicek, Mathieu ULg; Roberty, Stéphane ULg; Plaza, Sylvain et al

Poster (2010)

The gastropod Coralliophilla meyendorffi is a common predator of the zooxanthellate anemone Anemonia viridis. Zooxanthella from the anemones are an important constitutent of the mollusc faeces. Cell ... [more ▼]

The gastropod Coralliophilla meyendorffi is a common predator of the zooxanthellate anemone Anemonia viridis. Zooxanthella from the anemones are an important constitutent of the mollusc faeces. Cell integrity, occurence of flagellated forms, live/dead proportions and mitotic index of Symbiodinium collected from the faeces and cultivated in vitro were examined and compared to that of algae in hospite. The results show that most algae withstand digestive processes of the predator, staying alive and dividing actively in the faeces. Motile (lagellated) algae arise from dividing cells and escape the fecal pellets. Impact on coral bleaching recovery is discussed. [less ▲]

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See detailThe governance of fair trade social enterprises in Belgium
Huybrechts, Benjamin ULg

in Social Enterprise Journal (2010), 6(2), 110-124

Purpose – This article addresses the governance of “Fair Trade Social Enterprises” (FTSEs), i.e., the organisations exclusively dedicated to the import, distribution and/or labelling of fairly traded ... [more ▼]

Purpose – This article addresses the governance of “Fair Trade Social Enterprises” (FTSEs), i.e., the organisations exclusively dedicated to the import, distribution and/or labelling of fairly traded products. The aims are (1) to describe and categorise the types of persons and stakeholder groups represented in FTSEs’ governance structures and (2) to look at the link between stakeholder involvement and other organisational features such as resources, goals and activities. Design/methodology/approach – These questions are investigated through a qualitative field study based on face-to-face interviews with the managers of 15 Belgian FTSEs. Findings – I distinguish three governance models each entailing different governance paradigms: the managerial model, the volunteer-based model and the multi-stakeholder model. In the three governance models, it is possible to link, to a certain extent, the composition of the governance structures, the access to resources and the goal priorities regarding the different dimensions of the FT activity. In brief, governance appears as an organisational entry revealing much information about the vision and the strategy of the FTSEs. Research limitations/implications – This study is limited to Belgian FTSEs and must be considered as one of the first attempts in characterising the specific features and challenges of organisational governance in the FT context. International comparative studies exploring FTSE’s governance in a more longitudinal perspective, combining the standpoints of diverse organisational actors, would be most welcome in the future. Originality/value – As this article shows, the multidimensional nature of FT and the coexistence of different types of FTSEs in the same country make this a very interesting field to investigate the challenges of governance in social enterprises. Social enterprises and those researching them should pay more attention to the importance of adopting and conceiving governance schemes that are adapted to their multiple missions and enable the access to multiple resources. [less ▲]

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See detailHigher sensitivity of Adamts12-deficient mice to tumor growth and angiogenesis.
El Hour, Mehdi ULg; Moncada-Pazos, A.; Blacher, Silvia ULg et al

in Oncogene (2010), 29(20), 3025-32

ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin motifs) constitute a family of endopeptidases related to matrix metalloproteinases. These proteases have been largely implicated in ... [more ▼]

ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin motifs) constitute a family of endopeptidases related to matrix metalloproteinases. These proteases have been largely implicated in tissue remodeling and angiogenesis associated with physiological and pathological processes. To elucidate the in vivo functions of ADAMTS-12, we have generated a knockout mouse strain (Adamts12−/−) in which Adamts12 gene was deleted. The mutant mice had normal gestations and no apparent defects in growth, life span and fertility. By applying three different in vivo models of angiogenesis (malignant keratinocyte transplantation, Matrigel plug and aortic ring assays) to Adamts12−/− mice, we provide evidence for a protective effect of this host enzyme toward angiogenesis and cancer progression. In the absence of Adamts-12, both the angiogenic response and tumor invasion into host tissue were increased. Complementing results were obtained by using medium conditioned by cells overexpressing human ADAMTS-12, which inhibited vessel outgrowth in the aortic ring assay. This angioinhibitory effect of ADAMTS-12 was independent of its enzymatic activity as a mutated inactive form of the enzyme was similarly efficient in inhibiting endothelial cell sprouting in the aortic ring assay than the wild-type form. Altogether, our results show that ADAMTS-12 displays antiangiogenic properties and protect the host toward tumor progression. [less ▲]

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See detailOn (Omega-)regular model checking
Legay, Axel; Wolper, Pierre ULg

in ACM Transactions on Computational Logic (2010), 12(1), 46

Checking infinite-state systems is frequently done by encoding infinite sets of states as regular languages. Computing such a regular representation of, say, the set of reachable states of a system ... [more ▼]

Checking infinite-state systems is frequently done by encoding infinite sets of states as regular languages. Computing such a regular representation of, say, the set of reachable states of a system requires acceleration techniques that can finitely compute the effect of an unbounded number of transitions. Among the acceleration techniques that have been proposed, one finds both specific and generic techniques. Specific techniques exploit the particular type of system being analyzed, for example, a system manipulating queues or integers, whereas generic techniques only assume that the transition relation is represented by a finite-state transducer, which has to be iterated. In this article, we investigate the possibility of using generic techniques in cases where only specific techniques have been exploited so far. Finding that existing generic techniques are often not applicable in cases easily handled by specific techniques, we have developed a new approach to iterating transducers. This new approach builds on earlier work, but exploits a number of new conceptual and algorithmic ideas, often induced with the help of experiments, that give it a broad scope, as well as good performances. [less ▲]

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See detailLa porosité du droit : A propos des relations du droit avec d'autres disciplines
Sibony, Anne-Lise ULg

in Revue de la Faculté de Droit de l'Université de Liège (2010), (2), 271-278

Le droit est-il dans sa bulle ? Sans doute, il en sort pour entrer au contact des faits, mais ce n’est pas toujours facile. Quels chemins prend-il alors ? Cette leçon explorera l’hypothèse selon laquelle ... [more ▼]

Le droit est-il dans sa bulle ? Sans doute, il en sort pour entrer au contact des faits, mais ce n’est pas toujours facile. Quels chemins prend-il alors ? Cette leçon explorera l’hypothèse selon laquelle certaines sciences dites sociales peuvent l’aider à trouver sa route. Pour utiles que ces sciences soient pour le droit, elles n’en sont pas moins nombreuses et raffinées et les directions qu’elles indiquent peuvent paraître périlleuses. Aussi sera-t-il également question de la prudence que le droit a intérêt à observer lorsqu’il s’aventure sur la route des sciences. En somme, il s’agit de savoir comment le droit peut ouvrir sa bulle sélectivement aux connaissances scientifiques qui se prêtent à un usage juridique. [less ▲]

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See detailMaladie du greffon contre l'hôte chronique : une prise en charge multidisciplinaire
Servais, Sophie ULg; Willems, Evelyne ULg; Beguin, Yves ULg et al

in Revue Médicale de Liège (2010), 65

Chronic Graft-Versus-Host-Disease (GVHD) is a frequent complication of allogeneic hematopoietic cell transplantation. This review article describes recent advances in the classification and treatment of ... [more ▼]

Chronic Graft-Versus-Host-Disease (GVHD) is a frequent complication of allogeneic hematopoietic cell transplantation. This review article describes recent advances in the classification and treatment of chronic GVHD. [less ▲]

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See detailMolecular Reclassification of Crohn's Disease by Cluster Analysis of Genetic Variants
Cleynen, Isabelle; Mahachie John, Jestinah ULg; Henckaerts, Liesbet et al

in PLoS ONE (2010), 5(9), 12952

<sec> <title>Background</title> <p>Crohn's Disease (CD) has a heterogeneous presentation, and is typically classified according to extent and location of disease. The genetic susceptibility to CD is well ... [more ▼]

<sec> <title>Background</title> <p>Crohn's Disease (CD) has a heterogeneous presentation, and is typically classified according to extent and location of disease. The genetic susceptibility to CD is well known and genome-wide association scans (GWAS) and meta-analysis thereof have identified over 30 susceptibility loci. Except for the association between ileal CD and <italic>NOD2</italic> mutations, efforts in trying to link CD genetics to clinical subphenotypes have not been very successful. We hypothesized that the large number of confirmed genetic variants enables (better) classification of CD patients.</p> </sec><sec> <title>Methodology/Principal Findings</title> <p>To look for genetic-based subgroups, genotyping results of 46 SNPs identified from CD GWAS were analyzed by Latent Class Analysis (LCA) in CD patients and in healthy controls. Six genetic-based subgroups were identified in CD patients, which were significantly different from the five subgroups found in healthy controls. The identified CD-specific clusters are therefore likely to contribute to disease behavior. We then looked at whether we could relate the genetic-based subgroups to the currently used clinical parameters. Although modest differences in prevalence of disease location and behavior could be observed among the CD clusters, Random Forest analysis showed that patients could not be allocated to one of the 6 genetic-based subgroups based on the typically used clinical parameters alone. This points to a poor relationship between the genetic-based subgroups and the used clinical subphenotypes.</p> </sec><sec> <title>Conclusions/Significance</title> <p>This approach serves as a first step to reclassify Crohn's disease. The used technique can be applied to other common complex diseases as well, and will help to complete patient characterization, in order to evolve towards personalized medicine.</p> </sec> [less ▲]

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See detailSpectrométrie de masse MALDI-TOF en bactériologie clinique ou comment identifier une bactérie en une minute
MEEX, Cécile ULg

in Spectrométrie de masse MALDI-TOF en bactériologie clinique ou comment identifier une bactérie en une minute (2010)

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