The rationale to switch from postoperative hyperfractionated accelerated radiotherapy to preoperative hyperfractionated accelerated radiotherapy in rectal cancer

in International Journal of Radiation, Oncology, Biology, Physics (1995), 32(1), 181-188

To demonstrate the feasibility of preoperative Hyperfractionated Accelerated Radio Therapy (preop-HART) ini rectal cancer and to explain the rationales to switch from postoperative HART to preoperative ... [more ▼]

To demonstrate the feasibility of preoperative Hyperfractionated Accelerated Radio Therapy (preop-HART) ini rectal cancer and to explain the rationales to switch from postoperative HART to preoperative HART. View the MathML source: Fifty-two consecutive patients were introduced in successive Phase I trials since 1989. In trial 89-01, postoperative HART (48 Gy in 3 weeks) was applied in 20 patients. In nine patients with locally advanced rectal cancer, considered unresectable by the surgeon, 32 Gy in 2 weeks was applied prior to surgery (trial 89-02). Sicne 1991, 41.6 Gy in 2.5 weeks has been applied preoperative to 23 patients with T3—T4 any N recatl cancer immediately followed by surgery (trial 91-01). All patients were irradiated at the department of radiation-oncology with a four-field box technique (1.6 Gy twice a day and with at least a 6-h interval between fractions). The minimal accelerating potential was 6 MV. Acute toxicity was scored according to the World Health Organization (WHO for skin and small bowel) and the Radiation Therapy Oncology Group criteria (RTOG for bladder). This was done weekly during treatment and every 3 months thereafter. Small bowel volume was estimated by a modified “Gallagher's” method. View the MathML source: Acute toxicity was acceptable both in postoperative setup. The mean acute toxicity was significantly lower in trial 91-01 compared to 89-01. This difference was due to the smaller amount of small bowel in irradiation field and lower total dose in trial 91-01. Moreover, there was a significantly reduced delay between surgery and radiotherapy favoring trial 91-01 (median delay 4 days compared to 46 days in trial 89-01). Nearly all patients in trial 89-02 and 91-01 underwent surgery (31 out of 32; 97%). Resection margins were negative in 29 out of 32. Hospitalization duration in trial 91-01 was not significantly different from trial 89-01 (19 vs. 21 days, respectively). View the MathML source: Hyperfractionated accelerated radiotherapy immediately followed by surgery is feasible as far as acute toxicity is concerned. Preoperative HART is favored by a significantly lower acute toxicity related, in part, to a smaller amount of irradiated small bowel, and a shorter duration of the delay between radiotherapy and surgery. Moreover, the hospital stay after preoperative HART is not significantly increased [less ▲]

Comment j'explore ... Une anorexie mentale.

in Revue Médicale de Liège (1995), 50(12), 538-9

Prise en compte de l'enlèvement de matière dans le calcul des raideurs

Report (1995)

In the frame of the feasability study of machining simulation, this report is devoted to the study of the stiffness variation during the machining process

Quelques alternatives à la régression classique dans le cas de la colinéarité

in Revue de Statistique Appliquée (1995), XLIII(2), 5-33

In this note, we briefly describe some biased regresion methods : principal component regression, latent root regression analysis, partial least square regression, ridge regression and use of James-Stein ... [more ▼]

In this note, we briefly describe some biased regresion methods : principal component regression, latent root regression analysis, partial least square regression, ridge regression and use of James-Stein's estimators. All these methods are illustrated by an example. [less ▲]

Finite-amplitude regimes of the short-wave Marangoni-Benard convective instability.

in Physical Review. E : Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics (1995), 52(3), 2603-2616

L'inventaire forestier wallon : un outil de développement régional

Book published by Faculté des Sciences Agronomiques (1995)

This paper outlines the first permanent inventory carried out since the beginning of 1994 for monitoring and updating the forest resources in the Walloon region of Belgium (covering about 530.000 hectares ... [more ▼]

This paper outlines the first permanent inventory carried out since the beginning of 1994 for monitoring and updating the forest resources in the Walloon region of Belgium (covering about 530.000 hectares of forests). The so-called inventory is based upon a systematic sampling design which takes into account 1 plot to 50 ha (grid of 0,5 x 1 km). The main objectives are : to continuously monitor the changing situation of forest resources and focus attention on the wooded production, availability and probable trends in the future, to assist the formulation of the medium and the long-term development plan of the forestry sector, to provide information for long-term planning, control and improve general forest management programs. Methodological aspects are given concerning the survey design, the sampling units and the collection of data. The processing of data, the type and the presentation of expencted results are also briefly descriebed. Some recommandations concern the way which could be used in terms of organizational structure and logistical support. [less ▲]

Confirmation bias as a social skill

in Personality & Social Psychology Bulletin (1995), 21

Measurements of microbial N flow to the duodenum and urinary excretion of purine derivatives in bulls.

in Annales de Zootechnie (1995), 44

Numerical simulation of a full scale fire test on a loaded steel framework

in Journal of Constructional Steel Research (1995), 35

A single bay single storey steel portal frame has been tested under fire conditions. It is here simulated using hte non linear computer code CEFICOSS. The elements have composite steel-concrete sections ... [more ▼]

A single bay single storey steel portal frame has been tested under fire conditions. It is here simulated using hte non linear computer code CEFICOSS. The elements have composite steel-concrete sections for the thermal analysis, but only the steel part of the sections is load bearing. [less ▲]

Les scriptae françaises I. Wallonie

in Holtus, Günter; Metzeltin, Michael; Schmitt, Christian (Eds.) Lexicon der Romanistischen Linguistik, Band/Volume II, 2, Die einzelnen romanischen Sprachen und Sprachgebiete vom Mittelalter bis zur Renaissance / Les différentes langues romanes et leurs régions d'implantation du Moyen Âge à la Renaissance (1995)