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See detailImplanter un tableau de bord stratégique de type "Balanced ScoreCard" en contexte PME : pourquoi et comment ? Une étude de cas.
Van Caillie, Didier ULg; Kabwigiri, Charles ULg

Learning material (2005)

This conference discusses why it's interesting to integrate a Balanced ScoreCard in the performance management system used by a SME and highlights how to do so. An application to a case from the retail ... [more ▼]

This conference discusses why it's interesting to integrate a Balanced ScoreCard in the performance management system used by a SME and highlights how to do so. An application to a case from the retail industry is used as an example. [less ▲]

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See detailLe recours à une philosophie du droit dans la motivation de décisions juridictionnelles
François, Lucien ULg

in Journal des Tribunaux (2005)

Analyse d'une pathologie de l'argumentation : doctrine et jurisprudence fondant sur la seule "nature du droit international", c'est-à-dire sur une théorie du droit, la prééminence, en droit interne, de ... [more ▼]

Analyse d'une pathologie de l'argumentation : doctrine et jurisprudence fondant sur la seule "nature du droit international", c'est-à-dire sur une théorie du droit, la prééminence, en droit interne, de traités sur les lois même postérieures. Analysis of a pathology o argumentation : legal doctrine and case law relying on the 'nature of international law", hence on a general theory of law, in order to claim the pre-eminence, in internal law, of tratises over statutes even if enayed after them.l [less ▲]

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See detailLa gestion d’une organisation grâce aux tableaux de bord stratégiques : application au cas d'une officine hospitalière
Van Caillie, Didier ULg; Kabwigiri, Charles ULg

Conference given outside the academic context (2005)

This conference discusses what's performance management in an Hospital Pharmacy and proposes the use of a Balanced ScoreCard as a means to efficiently monitor this performance.

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See detailEvidence for HLA-DQA1 locus being associated with abdominal aortic aneurysms in the Belgian population
Ogata, T.; Gregoire, L.; Goddard, K. A. et al

in Circulation (2005, April 12), 111(14), 219

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See detailSpectroscopic determination of photospheric parameters and chemical abundances of 6 K-type stars
Affer, L.; Micela, G.; Morel, Thierry ULg et al

in Astronomy and Astrophysics (2005), 433

High resolution, high -S/N- ratio optical spectra have been obtained for a sample of 6 K-type dwarf and subgiant stars, and have been analysed with three different LTE methods in order to derive detailed ... [more ▼]

High resolution, high -S/N- ratio optical spectra have been obtained for a sample of 6 K-type dwarf and subgiant stars, and have been analysed with three different LTE methods in order to derive detailed photospheric parameters and abundances and to compare the characteristics of analysis techniques. The results have been compared with the aim of determining the most robust method to perform complete spectroscopic analyses of K-type stars, and in this perspective the present work must be considered as a pilot study. In this context we have determined the abundance ratios with respect to iron of several elements. In the first method the photospheric parameters (T_eff, log g, and ξ) and metal abundances are derived using measured equivalent widths and Kurucz LTE model atmospheres as input for the MOOG software code. The analysis proceeds in an iterative way, and relies on the excitation equilibrium of the ion{Fe}{i} lines for determining the effective temperature and microturbulence, and on the ionization equilibrium of the ion{Fe}{i} and ion{Fe}{ii} lines for determining the surface gravity and the metallicity. The second method follows a similar approach, but discards the ion{Fe}{i} low excitation potential transitions (which are potentially affected by non-LTE effects) from the initial line list, and relies on the B-V colour index to determine the temperature. The third method relies on the detailed fitting of the 6162 à ion{Ca}{i} line to derive the surface gravity, using the same restricted line list as the second method. Methods 1 and 3 give consistent results for the program stars; in particular the comparison between the results obtained shows that the ion{Fe}{i} low-excitation potential transitions do not appear significantly affected by non-LTE effects (at least for the subgiant stars), as suggested by the good agreement of the atmospheric parameters and chemical abundances derived. The second method leads to systematically lower T_eff and log g values with respect to the first one, and a similar trend is shown by the chemical abundances (with the exception of the oxygen abundance). These differences, apart from residual non-LTE effects, may be a consequence of the colour-T_eff scale used. The α-elements have abundance ratios consistent with the solar values for all the program stars, as expected for â normalâ disk stars. The first method appears to be the most reliable one, as it is self-consistent, it always leads to convergent solutions and the results obtained are in good agreement with previous determinations in the literature. Based on observations made with the Nordic Optical Telescope, operated on the island of La Palma jointly by Denmark, Finland, Iceland, Norway, and Sweden, in the Spanish Observatorio del Roche de los Muchachos of the Instituto de Astrofisica de Canarias. Table 6 is only available in electronic form at http://www.edpsciences.org [less ▲]

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See detailNew optical polarization measurements of quasi-stellar objects. The data
Sluse, Dominique ULg; Hutsemekers, Damien ULg; Lamy, H. et al

in Astronomy and Astrophysics (2005), 433

New linear polarization measurements (mainly in the V band) are presented for 203 quasi-stellar objects (QSOs). The sample is made up of 94 QSOs located in the North Galactic Pole (NGP) region and of 109 ... [more ▼]

New linear polarization measurements (mainly in the V band) are presented for 203 quasi-stellar objects (QSOs). The sample is made up of 94 QSOs located in the North Galactic Pole (NGP) region and of 109 QSOs in the South Galactic Pole (SGP) region. First time measurements have been obtained for 184 QSOs. Among them, 109 known radio-emitters, 42 known Broad Absorption Line (BAL) QSOs, and 1 gravitationally lensed quasi-stellar object. We found high polarization levels (p > 3%) for 12 QSOs, including the BAL QSO <ASTROBJ>SDSS J1409+0048</ASTROBJ>. For 10 objects, measurements obtained at different epochs do exist. Two of them show evidence for variability: the highly polarized BL Lac candidate <ASTROBJ>PKS 1216-010</ASTROBJ> and the radio source <ASTROBJ>PKS 1222+037</ASTROBJ>. Based on observations collected at the European Southern Observatory (ESO, La Silla and Paranal). Table 4 is only available in electronic form at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via http://cdsweb.u-strasbg.fr/cgi-bin/qcat?J/A+A/433/757 [less ▲]

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See detailInfliximab and the bone in Crohn's disease
Franchimont, N.; Reenaers, Catherine ULg; Louis, Edouard ULg

in Alimentary Pharmacology & Therapeutics (2005), 21(7), 918-919

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See detailSelf-referential reflective activity and its relationship with rest : a PET study
D'Argembeau, Arnaud ULg; Collette, Fabienne ULg; Van der Linden, Martial ULg et al

in NeuroImage (2005), 25(2), 616-624

This study used positron emission tomography (PET) to identify the brain substrate of self-referential reflective activity and to investigate its relationship with brain areas that are active during the ... [more ▼]

This study used positron emission tomography (PET) to identify the brain substrate of self-referential reflective activity and to investigate its relationship with brain areas that are active during the resting state. Thirteen healthy volunteers performed reflective tasks pertaining to three different matters (the self, another person, and social issues) while they were scanned. Rest scans were also acquired, in which subjects were asked to simply relax and not think in a systematic way. The mental activity experienced during each scan was assessed with rating scales. The results showed that, although self-referential thoughts were most frequent during the self-referential task, some self-referential reflective activity also occurred during rest. Compared to rest, performing the reflective tasks was associated with increased blood flow in the dorsomedial prefrontal cortex, the left anterior middle temporal gyros, the temporal pole bilaterally, and the right cerebellum; there was a decrease of blood flow in right prefrontal regions,and in medial and right lateral parietal regions. In addition, the ventromedial prefrontal cortex (VMPFC) (1) was more active during the self-referential reflective task than during the other two reflective tasks, (2) showed common activation during rest and the self-referential task, and (3) showed a correlation between cerebral metabolism and the amount of self-referential processing. It is suggested that the VMPFC is crucial for representing knowledge pertaining to the self and that this is an important function of the resting state. [less ▲]

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See detailWetting of bioactive glass surfaces by poly(alpha-hydroxyacid) melts: interaction between Bioglass (R) and biodegradable polymers
Blaker, Jonny J.; Maquet, Véronique; Boccaccini, Aldo R. et al

in e-Polymers (2005), 23

The interfacial characteristics between bioactive glass (4555 Bioglass(R)) surfaces and poly(alpha-hydroxyacid) melts have been assessed by direct wetting measurements. In particular, the wettability of ... [more ▼]

The interfacial characteristics between bioactive glass (4555 Bioglass(R)) surfaces and poly(alpha-hydroxyacid) melts have been assessed by direct wetting measurements. In particular, the wettability of Bioglass(R) powder by poly(D,L-lactide) (PDLLA) and poly(D,L-lactide-co-glycolide) (PLGA) was assessed by imbibition measurements. Additionally, the equilibrium contact angles of PDLLA and PLGA melts on a sintered Bioglass(R) surface were measured. The surface energy of the bioactive glass and the polymers was determined from contact angles measured using various test liquids on PDLLA, PLGA and Bioglass(R) solid substrates. There are sufficient adhesive interactions between the polymers and Bioglass(R). A simple heat treatment of the bioactive glass in an inert gas atmosphere leads to an improved wetting behaviour, indicating increased adhesive interactions. Scanning electron micrographs of the polymer+Bioglass(R) composites formed by polymer penetration into the powder bed show the formation of a 'good quality' interface. [less ▲]

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See detailL'astronomie dans le monde
Manfroid, Jean ULg

Article for general public (2005)

Missile galactique, Saturne, Mars, Mars Express, Age des cratères martiens, Cascade de glaciers, La première galaxie obscure détectée?, Masse stellaire limite, Rosetta, AT2 à Paranal, Un nouveau type d ... [more ▼]

Missile galactique, Saturne, Mars, Mars Express, Age des cratères martiens, Cascade de glaciers, La première galaxie obscure détectée?, Masse stellaire limite, Rosetta, AT2 à Paranal, Un nouveau type d'objet? [less ▲]

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See detailAbundance correlations in mildly metal-poor stars. II. Light elements (C to Ca)
Decauwer, Hélène; Jehin, Emmanuel ULg; Parmentier, Geneviève ULg et al

in Astronomy and Astrophysics (2005), 433

Accurate relative abundances have been obtained for carbon, oxygen, sodium, aluminium, silicon, and calcium in a sample of mildly metal-poor stars. This analysis complements a previous study carried out ... [more ▼]

Accurate relative abundances have been obtained for carbon, oxygen, sodium, aluminium, silicon, and calcium in a sample of mildly metal-poor stars. This analysis complements a previous study carried out by Jehin et al. ([CITE], A&A, 341, 241), which provided the basis for the EASE scenario. This scenario postulates that field metal-poor stars were born in self-enriched proto-globular cluster clouds. By further investigating the correlations between the different alpha-element abundances, we propose a modified scenario for the formation of intermediate metallicity stars, in which the stars exhibiting lower than average alpha/Fe abundance ratios would form in low mass clouds, unable to sustain the formation of very massive stars (M ⪠30~M_o). Moreover, the carbon-to-iron ratio is found to decrease as one climbs the so-called Population IIb branch, i.e. when the s-element abundance increases. In the framework of the EASE scenario, we interpret this anticorrelation between the carbon and the s-element abundances as a signature of a hot bottom burning process in the metal-poor AGB stars which expelled the matter subsequently accreted by our Population IIb stars. Based on observations collected at the European Southern Observatory, La Silla, Chile (ESO Programmes 56.E-0384, 57.E-0400 and 59.E-0257). [less ▲]

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See detailThe multi-ligand somatostatin analogue SOM230 inhibits ACTH secretion by cultured human corticotroph adenomas via somatostatin receptor type 5.
Hofland, Leo J.; van der Hoek, Joost; Feelders, Richard et al

in European Journal of Endocrinology (2005), 152(4), 645-654

Objective: Currently, there is no effective medical treatment for patients with pituitary-dependent Cushing’s disease. A novel somatostatin (SS) analogue, named SOM230, with high binding affinity to SS ... [more ▼]

Objective: Currently, there is no effective medical treatment for patients with pituitary-dependent Cushing’s disease. A novel somatostatin (SS) analogue, named SOM230, with high binding affinity to SS receptor subtypes sst1, sst2, sst3 and sst5 was recently introduced. We compared the in vitro effects of the sst2-preferring SS analogue octreotide (OCT) and the multi-ligand SOM230 on ACTH release by human and mouse corticotroph tumour cells. Methods: By quantitative RT-PCR the sst subtype expression level was determined in human corticotroph adenomas. In vitro, the inhibitory effect of OCT and SOM230 on ACTH release by dispersed human corticotroph adenoma cells and mouse AtT20 corticotroph adenoma cells was determined. In addition, the influence of dexamethasone on the responsiveness to OCT and SOM230 was studied. Results: Corticotroph adenomas expressed predominantly sst5 mRNA (six out of six adenomas), whereas sst2 mRNA expression was detected at significantly lower levels. In a 72 h incubation with 10 nmol/l SOM230, ACTH release was inhibited in three out of five cultures (range –30 to –40%). Ten nmol/l OCT slightly inhibited ACTH release in only one of five cultures (– 28%). In AtT20 cells, expressing sst2, sst3 and sst5, SOM230 inhibited ACTH secretion with high potency (IC50 0.2 nmol/l). Dexamethasone (10 nmol/l) pre-treatment did not influence the sensitivity of the cells to the inhibitory effect of SOM230, suggesting that sst5 is relatively resistant to negative control by glucocorticoids. Conclusions: The selective expression of sst5 receptors in corticotroph adenomas and the preferential inhibition of ACTH release by human corticotroph adenoma cells by SOM230 in vitro, suggest that SOM230 may have potential in the treatment of patients with pituitary-dependent Cushing’s disease. [less ▲]

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See detailA nation-wide project for the revision of the Belgian Nursing Minimum Data Set : from concept to implementation
SERMEUS, Walter; VAN DEN HEEDE, Koen; MICHIELS, Dominik et al

in OUD, Nico; SERMEUS, Walter; EHNFORS, Margareta (Eds.) Proceedings of the fifth biennial European Conference of the Association for Common European Nursing Diagnoses, Interventions and Outcomes (2005, April)

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See detailCriterion-related validity of the revised Belgian Nursing Minimium Data Set (B-NMDS) throught the actual B-NMDS
THONON, Olivier ULg; VAN BOVEN, Caroline ULg; CODOGNOTTO, Jean ULg et al

in OUD, Nico; SERMEUS, Walter; EHNFORS, Margareta (Eds.) Proceedings of the fifth biennial European Conference of the Association for Common European Nursing Diagnoses, Interventions and Outcomes (2005, April)

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See detailComment j'explore ... l'hypertension artérielle par excès de minéralocorticoides
Bovy, Christophe ULg; Delanaye, Pierre ULg; Radermecker, Régis ULg et al

in Revue Médicale de Liège (2005), 60(4), 255-63

Primary aldosteronism is a rare cause of hypertension. However, its incidence seems to be underestimated. It is important to identify this syndrom since the disease is potentially curable. In the present ... [more ▼]

Primary aldosteronism is a rare cause of hypertension. However, its incidence seems to be underestimated. It is important to identify this syndrom since the disease is potentially curable. In the present paper, we depict different forms of primary aldosteronism as well as the diagnostic procedures. When the diagnosis is suspected (hypertension associated to spontaneous or diuretic-induced hypokaliemia), the more efficient screening test is the determination of the aldosteron/renin ratio. Saline infusion or posture tests can thereafter confirm the diagnosis. Differential diagnosis between bilateral and unilateral forms of primary aldosteronism can be made by CT-scanner and the response of aldosterone to the posture test. Such a complex assessment leads to the identification of patients who can be surgically treated. This treatment consists in a unilateral adrenalectomy which can be realised by laparoscopy. [less ▲]

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See detailPsychiatrie de liaison en Unité de Transplantation cardiaque
Triffaux, Jean-Marc ULg

Learning material (2005)

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See detailApplication of Lempel-Ziv complexity to alignment-free sequence comparison of protein families
Bacha, Sofiène; Baurain, Denis ULg

Poster (2005, April)

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See detailInflammation et atherosclerose: etat de la question en 2004-2005
Gach, Olivier ULg; Pierard, Luc ULg; Legrand, Victor ULg

in Revue Médicale de Liège (2005), 60(4), 235-41

Inflammation plays a pivotal role in atherosclerosis; being present in all steps of the pathology, from initiation to the progression of the lesions to the development of vulnerable plaques and clinical ... [more ▼]

Inflammation plays a pivotal role in atherosclerosis; being present in all steps of the pathology, from initiation to the progression of the lesions to the development of vulnerable plaques and clinical destabilisation. Therefore, systemic markers of inflammation have emerged to predict future cardiovascular events in patients initially admitted for unstable syndromes, but also in healthy subjects. These markers can identify high risk patients and they are used to adapt ideal treatment to the patient's profile. The implication of the inflammation process in the treatment strategies is described in the last part of the article. [less ▲]

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See detailHLA-matched unrelated donor hematopoietic cell transplantation after nonmyeloablative conditioning for patients with chronic myeloid leukemia
Baron, Frédéric ULg; Maris, M. B.; Storer, B. E. et al

in Biology of Blood and Marrow Transplantation (2005), 11(4), 272-279

We evaluated 10/10 HLA antigen-matched unrelated hematopoietic cell transplantation (HCT) after nonmyeloablative conditioning with fludarabine 3 x 30 mg/m(2) and 2 Gy of total body irradiation as ... [more ▼]

We evaluated 10/10 HLA antigen-matched unrelated hematopoietic cell transplantation (HCT) after nonmyeloablative conditioning with fludarabine 3 x 30 mg/m(2) and 2 Gy of total body irradiation as treatment for patients with chronic myeloid leukemia who were ineligible for conventional HCT. Data from 21 consecutive patients in first chronic phase (CP1; n = 12), accelerated phase (AP; n = 5), second CP (CP2; n = 3), and blast crisis (n = 1) were analyzed. Stem cell sources were bone marrow (n = 4) or granulocyte colony-stimulating factor-mobilized peripheral blood mononuclear cells (G-PBMCs; n = 17). The patient who underwent transplantation in blast crisis died on day 21 (too early to be evaluated. for engraftment) from progressive disease. Sustained engraftment was achieved in 5 of 12 patients who underwent transplantation in CP1, 4 of 5 patients who underwent transplantation in AP, and 2 of 3 patients who underwent transplantation in CP2, whereas 9 patients rejected their grafts between 28 and 400 days after HCT. Specifically, I of 4 marrow recipients and 10 of 17 G-PBMC recipients achieved sustained engraftment. Graft rejections were nonfatal in all cases and were followed by autologous reconstitution with persistence or recurrence of chronic myeloid leukemia. Seven of 11 patients with sustained engraftment-including all 5 patients in CP 1, 2 of 4 patients in AP, and neither of the 2 patients in CP2-were alive in complete cytogenetic remissions 118 to 1205 days (median, 867 days) after HCT. Two of the remaining 4 patients died of nonrelapse causes in complete (n = 1) or major (n = 1) cytogenetic remissions, and 2 died of progressive disease. Further efforts are directed at reducing the risk of graft rejection by exclusive use of G-PBMC and increasing the degree of pretransplantation immunosuppression. (c) 2005 American Society for Blood and Marrow Transplantation. [less ▲]

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See detailThe reconstruction of an Atlantic salmon population in the Belgian River Meuse basin. First success and new threats.
Philippart, Jean-Claude ULg; Ovidio, Michaël ULg; Frank, Vincent et al

Conference (2005, April)

A 'Meuse Salmon' project aiming at restoring an Atlantic salmon run in the River Meuse basin was put forward in 1983 (after the discovery of several 'sea trout' in the Meuse near Liège) and started ... [more ▼]

A 'Meuse Salmon' project aiming at restoring an Atlantic salmon run in the River Meuse basin was put forward in 1983 (after the discovery of several 'sea trout' in the Meuse near Liège) and started officially in 1987 as a contribution of Wallonia to the European Year of Environment. In the course of this programme, most dams (3-8 m in height) obstructing the canalised River Meuse in Belgium and The Netherlands have been fitted with modern fish-ways in order to restore the free circulation of diadromous fish species. A second facet of the Salmon Meuse programme consisted in restocking salmonid streams in the Belgian Ardennes with hatchery reared salmon parr and smolt (maximum 200.000 fish per year) from foreign origins (Scotland, Ireland and France). Returning adult salmon have been scientifically recorded in the Meuse in The Netherlands (estuary and lower course) since 1994 but only since the year 2002 in Belgium: 13 (61-79 cm FL) fish in 2002 and 2 (71-76 cm FL) fish in 2003 caught mostly (13 fish) in a new big fish-pass at the Visé-Lixhe dam and (2 fish) in the River Berwinne, a small tributary of the Meuse known as the last spawning place for S. salar in Belgium in the 1920's. Female and male returning salmon in 2002 were successfully artificially reproduced in order to build a captive freshwater brood stock to be used for production of parrs and smolts of the new Meuse strain next autumn. The communication briefly reports on the progress of the program as concerns the salmon culture for stocking in Wallonia, the population dynamics of stocked parrs in nursery rivers, the patterns of upstream and downstream migration of salmon in the Belgian Meuse and its tributaries and the new challenges to meet (impact on salmon of rising water temperature, development of power generation, increasing predation on smolts by piscivorous birds). [less ▲]

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