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See detailA comparison of somatic cell count and antimicrobial susceptibility of subclinical mastitis pathogens in organic and conventional dairy herds
Boutet, Philippe; Detilleux, Johann ULg; Motkin, Michel ULg et al

in Annales de Médecine Vétérinaire (2005), 149(3), 173-182

A comparison of somatic cell count and antimicrobial susceptibility of subclinical mastitis pathogens in organic and conventional dairy herds.Bovine subclinical mastitis is the most important disease ... [more ▼]

A comparison of somatic cell count and antimicrobial susceptibility of subclinical mastitis pathogens in organic and conventional dairy herds.Bovine subclinical mastitis is the most important disease affecting dairy cows. The fluctuating increase in somatic cell count (SCC) that occurs causes major economic losses in dairy industry. This comparative study between conventional and organic dairy herds was conducted in the aim to better characterize which consequences might have different management practices on SCC but also on the frequency of pathogens isolated and their antimicrobial susceptibility. Four conventional and four organic herds, with bulk milk SCC >300x103cells/ml were selected, in which respectively 47 and 44 cows were investigated. Each quarter was sampled 3 times at 15 days interval for SCC, microbiological analysis and antimicrobial susceptibility. In both herd categories, major pathogens isolated were by order of importance Streptococcus uberis, Staphylococcus aureus and Streptococcus dysgalactiae with a great impact on SCC. Coagulase negative staphylococci were the most frequent minor germs and had a moderated but real impact on SCC. In certified organic dairy farms, the three most frequently isolated major pathogens were significantly more susceptible to antimicrobials in vitro. This study suggests that the limited use of antibiotics in organic dairy herds could explain, at least in part, the lower resistance obtained from analysed isolates. [less ▲]

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See detailSemantics of Collinearity Among Regions
Billen, Roland ULg; Clementini, Eliseo

in Lecture Notes in Computer Science (2005)

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See detailDesign, synthesis and evaluation of graftable thrombin inhibitors for the preparation of blood-compatible polymer materials.
Salvagnini, Claudio; Michaux, Catherine; Remiche, Julie ULg et al

in Organic & Biomolecular Chemistry (2005), 3(23), 4209-20

Piperazinyl-amide derivatives of N-alpha-(3-trifluoromethyl-benzenesulfonyl)-L-arginine (1) were synthesized as graftable thrombin inhibitors. The possible disturbance of biological activity due to a ... [more ▼]

Piperazinyl-amide derivatives of N-alpha-(3-trifluoromethyl-benzenesulfonyl)-L-arginine (1) were synthesized as graftable thrombin inhibitors. The possible disturbance of biological activity due to a variable spacer-arm fixed on the N-4 piperazinyl position was evaluated in vitro, against human alpha-thrombin, and in blood coagulation assay. Molecular modelling (in silico analysis) and X-ray diffraction studies of thrombin-inhibitor complexes were also performed. The fixation of bioactive molecules on poly(butylene terephthalate) (PBT) and poly(ethylene terephthalate) (PET) membranes was performed by wet chemistry treatment and evaluated by XPS analysis. Surface grafting of inhibitor 1d improved the membrane hemocompatibility by reducing blood clot formation on the modified surface. [less ▲]

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See detailEvolutionary ecology of facultative paedomorphosis in newts and salamanders
Denoël, Mathieu ULg; Joly, Pierre; Whiteman, Howard H.

in Biological Reviews (2005), 80(4), 663-671

Facultative paedomorphosis is an environmentally induced polymorphism that results in the coexistence of mature, gilled, and fully aquatic paedomorphic adults and transformed, terrestrial, metamorphic ... [more ▼]

Facultative paedomorphosis is an environmentally induced polymorphism that results in the coexistence of mature, gilled, and fully aquatic paedomorphic adults and transformed, terrestrial, metamorphic adults in the same population. This polymorphism has been of interest to scientists for decades because it occurs in a large number of caudate amphibian taxa as well as in a large diversity of habitats. Numerous experimental and observational studies have been conducted to explain the proximate and ultimate factors affecting these heterochronic variants in natural populations. The production of each alternative phenotype is based on a genotype x environment interaction and research suggests that differences in the environment can produce paedomorphs through several ontogenetic pathways. No single advantage accounts for the maintenance of this polymorphism. Rather, the interplay of different costs and benefits explains the success of the polyphenism across variable environments. Facultative paedomorphosis allows individuals to cope with habitat variation, to take advantage of environmental heterogeneity in the presence of open inches, and to increase their fitness. This process is expected to constitute a first step towards speciation events, and is also an example of biodiversity at the intraspecific level. The facultative paedomorphosis system is thus ripe for future studies encompassing ecology, evolution, behaviour, endocrinology, physiology, and conservation biology. Few other systems have been broad enough to provide varied research opportunities on topics as diverse as phenotypic plasticity, speciation, mating behaviour, and hormonal regulation of morphology. Further research on facultative paedomorphosis will provide needed insight into these and other important questions facing biologists. [less ▲]

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See detailRecommandations pour un programme de surveillance adapté aux objectifs de la DCE (recommandations concernat le benthos marins)
Guillaumont; Gauthier, E.; Gobert, Sylvie ULg

Report (2005)

L'application de la DCE nécessite la mise en place de contrôles pour évaluer l'état écologique des Masses d'eau côtières.

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See detailModélisation de la distribution spatiale des précipitations en Sicile.
Cornet, Yves ULg; Fitschy, C.; Gobbato, O. et al

in Bulletin de la Société Géographique de Liège (2005), 46

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See detailConnectieven, tekstbegrip en taalvaardigheid: de impact van causale connectieven op tekstbegrip door Franstalige leerders van het Nederlands
Perrez, Julien ULg; Degand, Liesbeth

in Hiligsmann, Philippe; Beheydt, Ludovic; Degand, Liebeth (Eds.) et al Neerlandistiek in Frankrijk en Franstalig België (2005)

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See detailHet gebruik van contrastieve connectieven door Franstalige leerders van het Nederlands
Perrez, Julien ULg

in Hiligsmann, Philippe; Janssens, Guy; Vromans, Joseph (Eds.) Woord voor Woord, Zin voor Zin, Liber Amicorum voor Siegfried Theissen (2005)

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See detailControlling the effects of anomalous ARP behaviour on ethernet networks
Ármannsson, D.; Hjálmt sson, G.; Smith, Paul et al

in Proceedings of the 2005 ACM conference on Emerging network experiment and technology (2005)

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See detailL’Observatoire de la Consommation alimentaire en Région wallonne : pourquoi, comment ?
Claustriaux, Jean-Jacques ULg; Cordier, Ludwig; Duquesne, Brigitte ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2005), 9(3), 207-212

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See detailStealth distributed hash table: unleashing the real potential of peer-to-peer
Brampton, A.; MacQuire, A.; Rai, I. A. et al

in Proceedings of the 2005 ACM conference on Emerging network experiment and technology (2005)

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See detailVariability of cotton diploid species SSR amplification in interspecific hybrids
Konan, N.O; Baudoin, Jean-Pierre ULg; Ben Bouza, H et al

in Proceedings of the plant & Animal Genome Conference XIII (2005)

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See detailDeepening a precautionary european policy
Deblonde, M.; du Jardin, Patrick ULg

in Journal of Agricultural & Environmental Ethics (2005), 18

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See detailCommon Agricultural Policy and the environment : are they compatible ?
Burny, Philippe ULg

in Universitatea "Babes-Boliay" Cluj-Napoca (Ed.) Simpozion national "Contributii stiintifice în tehnologii si echipamente pentru evaluarea si protectia mediului" (2005)

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See detailAnémie et risque cardiovasculaire chez l'insuffisant rénal
Krzesinski, Jean-Marie ULg

in Brochure "Roche" Ericabell (2005)

Le patient souffrant d'insuffisance rénale terminale est exposé à une mortalité de 5 à 30 fois supérieure à celle de la population générale à âge identique. Au moins 50% de cette surmortalité sont dus à ... [more ▼]

Le patient souffrant d'insuffisance rénale terminale est exposé à une mortalité de 5 à 30 fois supérieure à celle de la population générale à âge identique. Au moins 50% de cette surmortalité sont dus à des complications cardiovasculaires. Des signes de coronaropathie et d'insuffisance cardiaque sont déjà présents chez 40% de patients au début des traitements par dialyse. Ce risque cardiovasculaire apparaît très tôt dans le processus de dégradation de la fonction rénale et aumente au fur et à mesure de la progression de l'insuffisance rénale. Un patient souffrant de maladie rénale a plus de probabilité de décéder d'un problème cardiovasculaire que d'évoluer vers l'insuffisance rénale terminale. Plusieurs études épidémiologiques menées aux Etats-Unis, que ce soit l'étude NHANES III (National Health And Nutrition Examination Survey) ou encore l'étude ARIC (Atherosclerosis Risk in Communities), démontrent toutes que ce risque cardiovasculaire s'élève particulièrement dès que la filtration glomérulaire s'abaisse en dessous de 60 ml/min/1,73 m². Ceci vient d'être confirmé sur un suivi de près de 3 ans chez plus d'un million de sujets, tant pour le risque de décès, d'accidents cardiovasculaires que d'hospitalisations. Par ailleurs, le devenir de patients ayant présenté un infarctus du myocarde est plus sombre en présence d'une insuffisance rénale. Chaque diminution de 10 ml/min de la filtration glomérulaire, à partir de 80 ml/min, augmente le risque de complication de 10% chez des sujets ayant souffert d'un infarctus. [less ▲]

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See detailAnalysis of the vegetation trends using low resolution remote sensing data in the Sahel (1982-1999) for the monitoring of desertification
Hountondji, Yvon ULg; Sokpon, Nestor; Ozer, Pierre ULg

in Röder, Achim; Hill, Joachim (Eds.) Abstract Book - Remote Sensing and Geoinformation Processing in the Assessment and Monitorinf of Land Degradation and Desertification (2005)

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See detailUne modélisation de la communauté rigide
Dessoy, Etienne; Stassart, Martine ULg; Courtois, Anne et al

in Thérapie Familiale (2005), 26(1), 19-35

This paper is a modeling of the rigid community or clan which the organizing core is a «hidden antagonism». The family beliefs cluster the members around a joint project related to appearing and to having ... [more ▼]

This paper is a modeling of the rigid community or clan which the organizing core is a «hidden antagonism». The family beliefs cluster the members around a joint project related to appearing and to having it. But a subsystem develops and reintroduces a difference in this monolith. This subsystem is based on elements related to being and feeling, but also to ambiance, spirituality, aesthetics, suffering and pathology. This « hidden opposing » force dissimulated in the family « underground » remains unknown but works with an equal power to sustain the community unity. However, it uses radically different means than the dominating subsystem. Although each subsystem thinks it supports the system unity, it is more the conjunction of the two of them (in a hidden antagonism) that is the organizing principle of the clan. Cet article présente une modélisation du clan dont le principe organisateur est un « antagonisme caché ». Les croyances familiales unissent l'ensemble des membres autour d'un projet commun lié au paraître et à l'avoir. Mais un sous-système se construit, qui réintroduit une différence dans ce monolithe, à partir de valeurs proches de l'être et de l'éprouvé, des valeurs liées à l'ambiance, à la spiritualité, à l'esthétique, à la souf¬france et à la pathologie. Ce sous-système appelé «contestant caché », dissimulé dans le maquis familial, n'est reconnu par personne, et pourtant il agit avec autant de puissance que l'autre sous-système appelé « dominant», pour soutenir l'unité de la communauté, mais par des moyens radicalement opposés à ceux du sous-système «dominant». <br />Le processus organisateur du clan est donc animé par un antagonisme caché entre deux sous-systèmes dont chacun tente d'imposer ses propres moyens de produire l'unité, alors que le clan se nourrit de leur lutte sous-jacente. [less ▲]

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See detailInactivation of bacterial DD-peptidase by beta-sultams.
Llinas, Antonio; Ahmed, Naveed; Cordaro, Massimiliano et al

in Biochemistry (2005), 44(21), 7738-46

N-Acyl-beta-sultams are time-dependent, irreversible active site-directed inhibitors of Streptomyces R61 DD-peptidase. The rate of inactivation is first order with respect to beta-sultam concentration ... [more ▼]

N-Acyl-beta-sultams are time-dependent, irreversible active site-directed inhibitors of Streptomyces R61 DD-peptidase. The rate of inactivation is first order with respect to beta-sultam concentration, and the second-order rate constants show a dependence on pH similar to that for the hydrolysis of a substrate. Inactivation is due to the formation of a stable 1:1 enzyme-inhibitor complex as a result of the active site serine being sulfonylated by the beta-sultam as shown by ESI-MS analysis and by X-ray crystallography. A striking feature of the sulfonyl enzyme is that the inhibitor is not bound to the oxyanion hole but interacts extensively with the "roof" of the active site where the Arg 285 is located. [less ▲]

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