Publications ORBi OA
Bookmark and Share    
Full Text
Peer Reviewed
See detailEtiologies et exploration electrophysiologique des paralysies diaphragmatiques.
MAERTENS DE NOORDHOUT, Alain ULg

in Revue Neurologique (2004), 160(12), 1239-44

Detailed reference viewed: 5 (0 ULg)
Full Text
Peer Reviewed
See detailMotor cortex excitability in Alzheimer's disease and in subcortical ischemic vascular dementia.
Alagona, Giovanna; Ferri, Raffaele; Pennisi, Giovanni et al

in Neuroscience Letters (2004), 362(2), 95-8

Twenty Alzheimer's disease (AD) patients, 20 subcortical ischemic vascular dementia (SIVD) patients and 20 neurologically and cognitively normal subjects underwent transcranial magnetic stimulation to ... [more ▼]

Twenty Alzheimer's disease (AD) patients, 20 subcortical ischemic vascular dementia (SIVD) patients and 20 neurologically and cognitively normal subjects underwent transcranial magnetic stimulation to study motor cortex excitability changes. Motor threshold (MT), amplitude of motor evoked potentials, silent period and the H/M ratio (amplitude of maximal Hoffman reflex vs. that of maximal motor response) were considered. MT was lower in SIVD patients when compared with AD patients (P = 0.003) and the control group (P < 0.001) and lower in AD patients when compared with the control group (P < 0.001). The increment of motor cortex excitability in AD and SIVD did not lead us to distinguish clearly the two types of dementia. It is likely that the electrophysiological similarity between AD and SIVD could represent another common mechanism shared from these forms of dementia. [less ▲]

Detailed reference viewed: 14 (0 ULg)
Full Text
Peer Reviewed
See detailGraft-versus-tumor effects after allogeneic hematopoietic cell transplantation with nonmyeloablative conditioning
Baron, Frédéric ULg; Maris, Michael; Sandmaier, Brenda et al

in Blood (2004), 104

We have used a nonmyeloablative conditioning regimen consisting of 2 Gy total body irradiation +/– fludarabine, 30 mg/m²/day x 3 days, to condition elderly or ill patients (pts) with hematological ... [more ▼]

We have used a nonmyeloablative conditioning regimen consisting of 2 Gy total body irradiation +/– fludarabine, 30 mg/m²/day x 3 days, to condition elderly or ill patients (pts) with hematological malignancies for allogeneic hematopoietic cell transplantation (HCT). This approach relies almost exclusively on graft-versus-tumor (GVT) effects for control of malignancy. Here, we analyzed GVT effects in 322 pts with hematological malignancies given grafts from HLA-matched related (n=192) or unrelated (n=130) donors. Grades I, II, III and IV acute GVHD were seen in 26 (8.1%), 141 (43.8%), 34 (10.6%) and 11 (3.4%) pts, respectively. Extensive chronic GVHD was seen in 181 (56.2%) pts and of these, 64 (19.9%) cases had de novo chronic GVHD. Putative GVT effects were evaluated using time-dependent Cox regression models. Of the 221 pts with measurable disease at HCT, 126 (57%) achieved complete (n=98) or partial (n=28) remissions. Multivariate analysis identified chemosensitivity for B-cell malignancies (p=.02), and tandem autologous/allogeneic HCT (p=.04) as pre-transplant factors associated with higher probabilities of achieving complete remissions (CR) after HCT. After adjusting for these factors, acute GVHD of any grade was not found to be associated with an increased probability of achieving CR. There was a trend for a higher probability of achieving CR in pts with chronic GVHD (p=.07). Progression/relapse was observed in 108 pts. Multivariate analysis identified that lower disease-risk (p=.0004), tandem autologous/allogeneic HCT (p=.02) and adapted Charlson comorbidity index (CCI) score at transplant < 3 (p=.002) resulted in significantly decreased risk of progression/relapse. After correcting for these factors, extensive chronic GVHD was associated with a decreased risk of progression/relapse (p=.006). Pts with grade 1 acute GVHD tended to have less progression/relapse (p=.07). Conversely, grade II–IV acute GVHD did not significantly affect the risk of progression/relapse. Nonrelapse mortality was observed in 70 pts. Multivariate analysis showed that lower disease-risk (p=. 001), tandem autologous/allogeneic HCT (p=.002) and CCI score at transplant < 3 (p<.0001) significantly decreased nonrelapse mortality. After adjusting for these variables, grade II (p=.04) and grade III–IV (p<.0001) acute GVHD increased nonrelapse mortality while extensive chronic GVHD did not. The 3-year probability of progression-free survival (PFS) was 38.5%. In multivariate analysis, lower disease-risk (p<.0001), tandem autologous/allogeneic HCT (p=.0008) and CCI score at transplant < 3 (p<.0001) resulted in significantly better PFS. After adjusting for theses variables, grade 1 acute GVHD (p=.02) and chronic extensive GVHD (p=.003) were both associated with significantly better PFS, while grade III–IV acute GVHD (p<.0001) was associated with decreased PFS. In summary, chronic GVHD in pts given nonmyeloablative conditioning was associated with substantial GVT effects which led to improved PFS. Conversely, any potential GVT benefits from grade II–IV acute GVHD were offset by higher nonrelapse mortality resulting in worse PFS. Efforts should be directed at reducing the risk of grade II–IV acute GVHD while allowing de novo chronic GVHD for best PFS after allogeneic HCT with nonmyeloablative conditioning. [less ▲]

Detailed reference viewed: 5 (0 ULg)
Full Text
Peer Reviewed
See detailApplications cliniques de la stimulation magnetique transcranienne repetitive.
MAERTENS DE NOORDHOUT, Alain ULg

in Revue Médicale de Liège (2004), 59 Suppl 1

Transcranial magnetic stimulation (TMS), when delivered in trains of pulses is able to induce long-lasting changes of excitability of neuronal networks, not only in the vicinity of the stimulating coil ... [more ▼]

Transcranial magnetic stimulation (TMS), when delivered in trains of pulses is able to induce long-lasting changes of excitability of neuronal networks, not only in the vicinity of the stimulating coil, but also at distant sites. Results of stimulation experiments over the motor cortex indicate that the effects (excitatory or inhibitory) depend on the frequency of stimulation. These data have prompted researchers to use repetitive transcranial magnetic stimulation (rTMS) as a therapeutic tool in various brain disorders, most notably depression. However, as long as large randomized trials have not been conducted, rTMS cannot be recommended as an alternative to validated conventional therapies of such disorders. [less ▲]

Detailed reference viewed: 54 (2 ULg)
Full Text
See detailLes garçons et l’engagement dans la lecture ; une histoire impossible ?
Schillings, Patricia ULg

in Caractères (2004), 16(6-12),

Detailed reference viewed: 10 (1 ULg)
Full Text
See detailL'emploi dans l'économie sociale marchande en Région wallonne
Fecher-Bourgeois, Fabienne ULg; Thiry, Bernard ULg; Raponi, Michael et al

Report (2004)

Detailed reference viewed: 26 (4 ULg)
Full Text
Peer Reviewed
See detailNouvelles recherches dans l'enceinte de la Schola du Trajan à Ostie
Morard, Thomas ULg

in Revue Archeologique (2004), XXXIV(2002-2003), 204-209

Detailed reference viewed: 18 (4 ULg)
Full Text
Peer Reviewed
See detailTerrestrial versus aquatic foraging in juvenile Alpine newts (Triturus alpestris)
Denoël, Mathieu ULg

in Ecoscience (2004), 11(4), 404-409

Many species of newts and salamanders forage in both terrestrial and aquatic environments during their life. However, the relative benefits of the two foraging patterns remain unknown because all previous ... [more ▼]

Many species of newts and salamanders forage in both terrestrial and aquatic environments during their life. However, the relative benefits of the two foraging patterns remain unknown because all previous studies have focused on only one habitat. The aim of this study was to find out which foraging tactic is the most successful in terms of energy intake. To this end, I analyzed trophic habits in metamorphosed juveniles in the Alpine newt, Triturus alpestris veluchiensis, inhabiting an alpine lake (Drakolimni) and the surrounding lands (Tymphi Mountains, northern Greece). The diet of the newts reflected the range of prey available in the two habitats, but aquatic newts also foraged on invertebrates that fell on the water surface. The two lifestyles have different energy outcomes. Terrestrial invertebrates provided high energy gains mainly to terrestrial juveniles because of the low number of this prey type in the lake. However, terrestrial juveniles are expected to suffer higher mortality (freezing on land is more probable than in deep waters) and a lower energy intake when air temperature is low, i.e., the main pattern in high-elevation sites, except during mid-summer. Persistence of the aquatic foraging tactics in the population may depend on a trade-off between costs and benefits. [less ▲]

Detailed reference viewed: 233 (10 ULg)
Full Text
Peer Reviewed
See detailA thermo-hydro-mechanical constitutive model and its numerical modelling for unsaturated soils
Wu, Wenhua; Li, Xikui; Charlier, Robert ULg et al

in Computers & Geotechnics (2004), 31(2),

A thermo-hydro-mechanical (THM) constitutive model for unsaturated soils is proposed in this paper based on the existing models. The influences of temperature on the hydro-mechanical behaviour in ... [more ▼]

A thermo-hydro-mechanical (THM) constitutive model for unsaturated soils is proposed in this paper based on the existing models. The influences of temperature on the hydro-mechanical behaviour in unsaturated soils are described in the model. Particularly, the thermal softening phenomenon, i.e. decreases in value of the pre-consolidation pressure and in critical value of the suction of the SI (suction increasing) curve with heating process, is quantitatively modelled by using the experimental data and previous work [J. Geotech. Eng. ASCE 116 (12) (1990) 1765; J. Geotech. Eng. ASCE 116 (12) (1990) 1778; Can. Geotech. J. 25 (1988) 807; Int. J. Numer. Anal. Meth. Geomech. 22 (1998) 549; Can. Geotech. J. 37 (2000) 607; Characterisation and thermo-hydro-mechanical behaviour of unsaturated Boom clay: an experimental study. Thesis Doctoral 1999, Technical University of Catalonia (UPC), Barcelona, Spain]. Numerical modelling of the proposed THM model has also been implemented within the finite element code LAGACOM. Finally, the comparisons of the results obtained from the numerical modelling of the constitutive behaviour with existing experimental results show that the present model can simulate the thermo-hydro-mechanical behaviour in unsaturated soils with satisfaction. Some other numerical results given in the paper also validate the versatility and applicability of the present constitutive model. (C) 2004 Elsevier Ltd. All rights reserved. [less ▲]

Detailed reference viewed: 69 (7 ULg)
Full Text
Peer Reviewed
See detailOn the collapse behaviour of oil reservoir chalk
De Gennaro, Vincenzo; Delage, Pierre; Priol, Grégoire et al

in Geotechnique (2004), 54(6), 415-420

Oil exploitation in North Sea Ekofisk oilfield started in 1971, the reservoir is located in a 150 m thick layer of porous chalk (n = 40-50%) at a 3000 m depth. Enhanced oil recovery procedure by sea water ... [more ▼]

Oil exploitation in North Sea Ekofisk oilfield started in 1971, the reservoir is located in a 150 m thick layer of porous chalk (n = 40-50%) at a 3000 m depth. Enhanced oil recovery procedure by sea water injection (waterflooding) was initiated in 1987. Starting from this date, seabed subsidence due to chalk compaction evolves at a fairly constant rate (i.e. 40 cm/year). Nowadays, the decrease of the seafloor level is of about 10 m. Reservoir management and production strategies are at the origin of the growing interest of petroleum industry in disposing of a comprehensive description of the chalk mechanical behaviour. In this note the subsidence due to waterflooding is interpreted within a framework taken from the mechanics of unsaturated soils. By considering oil as the non-wetting fluid and water as the wetting fluid, chalk compaction is depicted as a collapse phenomenon due to oil-water suction decrease. A series of suction controlled tests in the osmotic oedometer cell are presented. Water weakening effects and chalk compaction (collapse) seem likely to occur through the lost of strength of the inter-granular links existing in the oil saturated sample. The nature of these links includes both capillary and physico-chemical fluids-chalk interactions, and is well characterised by the oil-water suction. [less ▲]

Detailed reference viewed: 122 (5 ULg)
Full Text
Peer Reviewed
See detailFeeding performance in heterochronic alpine newts is consistent with trophic niche and maintenance of polymorphism
Denoël, Mathieu ULg

in Ethology (2004), 110(2), 127-136

The feeding performances of two heterochronic morphs of the Alpine newt Triturus alpestris were investigated in laboratory experiments. Although both morphs are able to feed in the aquatic habitat, the ... [more ▼]

The feeding performances of two heterochronic morphs of the Alpine newt Triturus alpestris were investigated in laboratory experiments. Although both morphs are able to feed in the aquatic habitat, the hydrodynamics of prey capture differ between morphs. In paedomorphs water sucked with prey is expelled behind the mouth through gill bars. In metamorphs, water is expelled by the mouth as gill slits are closed. Feeding performance was better in paedomorphs than in metamorphs when foraging on aquatic crustaceans, but paedomorphs were less successful when foraging on terrestrial invertebrates caught at the water surface. These differences in prey capture success related to prey type allow the two morphs to use specific resources in their aquatic habitat. These results are consistent with previous studies that showed diet differentiation between morphs in natural populations. Such resource partitioning is a factor favouring the maintenance of facultative paedomorphosis in natural populations. [less ▲]

Detailed reference viewed: 109 (9 ULg)
Full Text
See detailLa libre circulation des personnes dans l’Union européenne (1er janvier - 31 décembre 2003)
Carlier, Jean-Yves ULg

in Journal de Droit Européen [=JDE] (2004), 12(107), 74

Detailed reference viewed: 4 (0 ULg)
Full Text
See detailPoesia e cenário : o interior, o excesso, o nada – a propósito do “Lamento das puberdades difíceis”
Durand, Pascal ULg

in Inimigo Rumor, Revista de poesia (2004), 16(1er semestre),

Detailed reference viewed: 23 (9 ULg)
Full Text
Peer Reviewed
See detailEffect of cardiac resynchronization therapy on functional mitral regurgitation in heart failure.
Lancellotti, Patrizio ULg; MELON, Pierre ULg; SAKALIHASAN, Natzi ULg et al

in American Journal of Cardiology (2004), 94(11), 1462-5

Cardiac resynchronization therapy (CRT) reduces functional mitral regurgitation (MR) at rest. This study assessed exercise-induced changes in MR in patients with heart failure who were helped by CRT. The ... [more ▼]

Cardiac resynchronization therapy (CRT) reduces functional mitral regurgitation (MR) at rest. This study assessed exercise-induced changes in MR in patients with heart failure who were helped by CRT. The determinants of these exercise-induced changes in MR were analyzed in asynchronous and resynchronized left ventricles. [less ▲]

Detailed reference viewed: 19 (6 ULg)
Full Text
Peer Reviewed
See detailIdentification of material parameters using bi-axial machine
Flores, Paulo; de Montleau, P.; Mathonet, V. et al

in Stören, Sigurd (Ed.) Proceedings of the 7th ESAFORM conference on Materials Forming (2004)

Experimental testing equipment is built in order to identify material parameters of complex phenomenological constitutive laws. This equipment consists in a bi-axial test machine able to perform plane ... [more ▼]

Experimental testing equipment is built in order to identify material parameters of complex phenomenological constitutive laws. This equipment consists in a bi-axial test machine able to perform plane strain and simple shear tests separately or simultaneously and a Miyauchi simple shear test device; an optical extensometer is used to identify the strain field. The article focus on the validation of the results of this new equipment by comparing with results obtained by standard machines and/or by using FEM simulations of already identified materials. The first results show that the bi-axial machine performs the plane strain test optimally and some modifications are proposed in order to improve the results for the simple shear test. Miyauchi device shows a good performance and the experimental results are compared with a FEM simulation. [less ▲]

Detailed reference viewed: 34 (2 ULg)
Full Text
See detailSubdivision of the Famennian Stage into four substages and correlation with the neritic and continental Miospore Zonation
Streel, Maurice ULg

in Newsletter. Subcommission on Devonian Stratigraphy (2004), 21

Detailed reference viewed: 8 (0 ULg)