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See detailSivers function in constituent quark models
Scopetta, S.; Courtoy, Aurore ULg; Fratini, F. et al

in World scientific (2008)

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See detailHigh-Precision Spectroscopy of Pulsating Stars
Aerts, C.; Hekker, S.; Desmet, M. et al

in Precision Spectroscopy in Astrophysics, Proceedings of the ESO/Lisbon/Aveiro Conference held in Aveiro, Portugal, 11-15 September 2006. (2008)

We review methodologies currently available to interprete time series of high-resolution high-S/N spectroscopic data of pulsating stars in terms of the kind of (non-radial) modes that are excited. We ... [more ▼]

We review methodologies currently available to interprete time series of high-resolution high-S/N spectroscopic data of pulsating stars in terms of the kind of (non-radial) modes that are excited. We illustrate the drastic improvement of the detection treshold of line-profile variability thanks to the advancement of the instrumentation over the past two decades. This has led to the opportunity to interprete line-profile variations with amplitudes of order m/s, which is a factor 1000 lower than the earliest line-profile time series studies allowed for. [less ▲]

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See detailThe Chemical Composition of B-type Pulsators: Some Unexpected Results
Morel, Thierry ULg; Briquet, Maryline ULg; Aerts, C.

in Precision Spectroscopy in Astrophysics (2008)

We present a project aimed at self-consistently deriving the physical parameters and chemical composition of massive pulsators (β, Cephei stars, Slowly Pulsating B stars) based on high-resolution optical ... [more ▼]

We present a project aimed at self-consistently deriving the physical parameters and chemical composition of massive pulsators (β, Cephei stars, Slowly Pulsating B stars) based on high-resolution optical spectra. Such data will be essential for a proper theoretical interpretation of their oscillation spectrum, but may also contribute in a broader context to our understanding of mixing and diffusion processes in B-type stars. As an illustration, our first results reveal the existence of core-processed material at the surface of some slowly-rotating β, Cephei stars which is not predicted by current evolutionary models including rotation. [less ▲]

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See detailEpidemiology and Genetics of Pituitary Tumours
Daly, Adrian ULg

Doctoral thesis (2008)

To have a full understanding of a disease, it is necessary to at least know how frequently it occurs, its clinical features and by what means it is caused. In the case of pituitary adenomas, data in the ... [more ▼]

To have a full understanding of a disease, it is necessary to at least know how frequently it occurs, its clinical features and by what means it is caused. In the case of pituitary adenomas, data in the literature on the epidemiology of these tumors is conflicting, with some studies suggesting a high frequency, others that they occur rarely in the clinical setting. In parallel, the understanding of the pathophysiology of endocrine tumors like pituitary adenomas has advanced greatly with the advent of molecular genetic techniques. However, much remains unclear regarding pathophysiology. A valuable avenue for studying the causes of endocrine tumors has been to focus on the familial setting. With respect to pituitary adenomas, apart from multiple endocrine neoplasia type 1 (MEN1) and Carney complex (CNC), the field of familial pituitary tumors is poorly understood. Indeed, apart from familial acromegaly, there have been virtually no studies on other pituitary adenomas occurring in the familial setting. The aims of the work described in this thesis were based on addressing aspects of the epidemiology and genetics of pituitary tumors. Firstly, the disconnect between the prevalence rates for pituitary adenomas from autopsy/radiology studies (incidentalomas being very common) and cancer registries/population data (rare) was studied. An intensive, comprehensive, case-finding study of the prevalence of pituitary adenomas was performed in three tightly-defined geographical areas in the Province of Liège. In this study, which involved a population of more than 70,000 people, diagnosed pituitary adenomas were sought in collaboration with the entire group of community medical practitioners in the study areas, and the demographics and clinical, hormonal, radiological and pathological features of all patients were confirmed independently. On a fixed date, it was found that clinically diagnosed pituitary adenomas occurred with a prevalence of 1 case per 1064 individuals residing within the geographic boundaries of the study. These results report a clinical prevalence of pituitary adenomas that is 3.5 to 5 times higher than previous population/registry estimates. It suggests that clinically relevant pituitary adenomas occur frequently in the everyday clinical setting, which may have important implications for health resource allocations. Also, it is possible to undertake detailed, comprehensive, crosssectional epidemiological studies in well-defined geographic areas, and this methodology can be applied internationally Studying the familial occurrence of pituitary adenomas outside of MEN1 and CNC was the next aim of the work described. Up to this time, only the familial occurrence of acromegaly had been reported with any frequency in the literature. An international study was undertaken to assess whether isolated pituitary adenomas of all types could occur in the familial setting, a suspicion raised in Liège over the past decade. This study demonstrated that familial isolated pituitary adenomas (FIPA) occur in about 2% of pituitary adenoma populations, and 64 FIPA families were characterized clinically. The study demonstrated for the first time that all phenotypes of pituitary adenomas can occur together in families; some families exhibit only one phenotype among affected members (homogeneous FIPA kindreds), others have multiple tumor types among affected family members (heterogeneous FIPA). In FIPA families, pituitary tumors were more aggressive and tended to occur at a younger age than sporadic pituitary adenomas. FIPA families display a high degree of familiality, suggesting a dominant mode of inheritance. Subsequent studies were performed on the genetic and pathological features of pituitary adenomas, particularly those occurring as FIPA. The discovery of a novel gene, aryl hydrocarbon receptor interacting protein ( AIP), mutations in which were associated with isolated pituitary adenomas, led us to undertake the first such genetic studies in FIPA. AIP mutations account for a minority (15%) of FIPA families and 50% of familial acromegaly kindreds in FIPA. This suggests that other genetic causes for FIPA also exist. In AIP mutation carrying FIPA families, tumors were larger and had a younger age at diagnosis than non- AIP mutated FIPA kindreds. A series of 9 novel AIP mutations were identified, the majority of which led to predicted loss of vital ligand and receptor interacting regions of the AIP protein. AIP mutations in FIPA were associated with multiple pituitary adenoma types, including acromegaly, prolactinomas, mixed growth hormone/prolactin secreting adenomas and non-secreting tumors. It was also found that the same AIP mutation was responsible for different pituitary adenoma types in two separate FIPA families. A detailed follow-up study of an individual FIPA kindred with an AIP mutation found for the first time that non-pituitary tumor-associated endocrine abnormalities (elevated circulating insulin-like growth factor-1) occur in AIP mutation carriers. A detailed analysis of germline and somatic DNA from a large international European cohort of sporadic (non-familial) pituitary adenoma cases showed that AIP mutations occur rarely in this setting. In conclusion, the work undertaken has provided new understanding of the true prevalence of clinically-relevant pituitary adenomas in the population, in addition to codifying and characterizing FIPA, a new clinical entity that represents a potentially valuable area for genetic and clinical studies involving the function of AIP and other as yet unidentified associated genetic causes. [less ▲]

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See detailTornades, vents exceptionnels et constructions
Denoël, Vincent ULg

Learning material (2008)

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See detailApplication of a three-field natural neighbour method in elastoplasticity
Li, Xiang; Cescotto, Serge ULg; Duchene, Laurent ULg

in Proceedings of the 8th World Congress on Computational Mechanics (WCCM8) (2008)

The natural neighbour method can be considered as one of the many variants of the meshless methods. Classically, the development of these methods is based on the virtual work principle: a set of nodes are ... [more ▼]

The natural neighbour method can be considered as one of the many variants of the meshless methods. Classically, the development of these methods is based on the virtual work principle: a set of nodes are distributed over the domain to be studied and the displacement field is discretized with the help of interpolation functions that are not based on the finite element concept but only based on the nodes. In the present paper, we use a new approach based on the Fraeijs de Veubeke (FdV) functional [1] and initially developed for linear elasticity [2]. It uses separate discretizations of the displacements, stresses and strains. The method of [2] is extended to the case of geometrically linear but materially non linear solids and it is shown that, in the absence of body forces, the calculation of integrals over the area of the domain is avoided and that the derivatives of the nodal shape functions are not required, which constitutes an advantage over classical meshless and finite elements methods. [less ▲]

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See detailDisorders of mitochondrial function
Debray, François-Guillaume ULg; Lambert, M.; Mitchell, G. A.

in Current Opinion in Pediatrics (2008), 20(4), 471-482

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See detailINTAKE OF DIOXINS AND DIOXIN-LIKE PCBs CONSUMING HOME PRODUCED VERSUS COMMERCIAL EGGS
Sioen, Isabelle; Bilau, Maaike; Van Overmeire, Ilse et al

in Organohalogen Compounds (2008)

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See detailANALYSIS OF DIOXINS AND DIOXIN-LIKE PCBS IN HOME PRODUCED EGGS: LEVELS AND SOURCES
Van Overmeire, Ilse; Eppe, Gauthier ULg; Waegeneers, Nadia et al

in Organohalogen Compounds (2008)

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See detailAn elasto-viscoplastic model for chalk including suction effects
Collin, Frédéric ULg; De Gennaro, Vincenzo; Delage, Pierre et al

in Toll, David (Ed.) Unsaturated Soils: Advances in Geo-Engineering (2008)

During the six years long Pasachalk project devoted to the mechanical behaviour of high porosity chalks from North Sea oilfields, the constitutive model Pasachalk (Collin et al., 2002) was proposed based ... [more ▼]

During the six years long Pasachalk project devoted to the mechanical behaviour of high porosity chalks from North Sea oilfields, the constitutive model Pasachalk (Collin et al., 2002) was proposed based on the Barcelona Basic Model (BBM) (Alonso et al., 1990). The approach was based on the similarities found between the oil-water interactions (oil and water being the non wetting and wetting fluid respectively) in oil reservoir chalk and the air-water interactions in unsaturated soils. This approach appeared to be relevant to in-terpret the subsidence of the seafloor during waterflooding operations for enhanced oil recovery that has been observed in North Sea oilfields (e.g. Ekofisk oilfield). Another important component of subsidence was then related to the creep behaviour of the multiphase chalk (De Gennaro et al., 2003). A modified Pasachalk model was proposed to account for time effects using the framework of Perzyna’s viscoplasticity (1964) but without considering suction effects. Based on available experimental results (Priol et al., 2007), a modified version of the viscoplastic Pasachalk model including suction effects is proposed in this paper. [less ▲]

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See detailMorphological recognition of artificial F1 hybrids between three common European cyprinid species: Rutilus rutilus, Blicca bjoerkna and Abramis brama.
Matondo, B. N.; Ovidio, Michaël ULg; Poncin, Pascal ULg et al

in Dong Wu Xue Bao = Acta Zoologica Sinica (2008), 54(1),

The F1 hybrids of roach Rutilus rutilus, silver bream Blicca bjoerkna, and common bream Abramis brama from experimental reciprocal cross-breedings were identified at 18 months of age in relation to the ... [more ▼]

The F1 hybrids of roach Rutilus rutilus, silver bream Blicca bjoerkna, and common bream Abramis brama from experimental reciprocal cross-breedings were identified at 18 months of age in relation to the parental species. The morphological analysis, including quantitative (plastic and meristic) and nonmetric features differing in the roach, the silver bream and the common bream, revealed that roach * common bream and roach * silver bream hybrids were easier to distinguish from their parents than silver bream * common bream hybrids. These roach hybrids had many morphological similarities such as the upper iris coloured in red as in the roach, and they were morphologically intermediate to the two parents. This contrasted with the silver bream * common bream hybrids, in which intermediate characteristics were also observed, but with some parental variants. Roach * silver bream hybrids were distinguishable from roach * common bream hybrids by its large eye, its lower scale numbers along the lateral line and its two rows of pharyngeal teeth. Silver bream * common bream hybrids, compared to the two other types of hybrids studied, had higher anal fin soft ray numbers and a clear eye iris with a median black line. In all interspecific crosses of these three cyprinid species fish, the reciprocal hybrids were generally indistinguishable. [less ▲]

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See detailA shimming procedure for fMRI, optimizing the local BOLD sensitivity
Balteau, Evelyne ULg; Weiskopf, Nikolaus

in Proceedings of the International Society for Magnetic Resonance in Medicine (2008), 16

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See detailA robust automated shimming procedure for breast MR spectroscopy
Balteau, Evelyne ULg; Charles-Edwards, GD

in Proceedings of the International Society for Magnetic Resonance in Medicine (2008), 16

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See detailIntegrating soil and plant knowledge at different scales to better understand the dynamics of water in SPAC.
Lobet, Guillaume ULg; Pagès, L.; Chaumont, F. et al

Conference (2008)

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See detailEncore un pas vers la standardisation internationale du dosage d'HbA1c
Gillery; Bordas-fonfrède; Chapelle, Jean-Paul ULg et al

in Annales de Biologie Clinique (2008), 66(1), 6-8

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See detailInfluence of nitrogen fertilizer treatments on soft wheat starch characteristics
Massaux, Carine; Sindic, Marianne ULg; Lenartz, Jonathan et al

Poster (2008)

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