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See detailCongenital genralized lipodystrophy in an Indian patient with a novel mutation in BSCL2 gene
Shirwalkar, H. U.; Patel, Z. M.; Magre, J. et al

in Journal of Inherited Metabolic Disease (2008), 12

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See detailCluster expansion method for evolving weighted networks having vector-like nodes
Ausloos, Marcel ULg; Gligor, M.

in Acta Physica Polonica A (2008), 114(3), 491-499

The cluster variation method known in statistical mechanics and condensed matter is revived for weighted bipartite networks. The decomposition (or expansion) of a Hamiltonian through a finite number of ... [more ▼]

The cluster variation method known in statistical mechanics and condensed matter is revived for weighted bipartite networks. The decomposition (or expansion) of a Hamiltonian through a finite number of components, whence serving to define variable clusters, is recalled. As an illustration the network built from data representing correlations between (4) macroeconomic features, i.e. the so-called vector components, of 15 EU countries, as (function) nodes, is discussed. We show that statistical physics principles, like the maximum entropy criterion points to clusters, here in a (4) variable phase space: Gross Domestic Product, Final Consumption Expenditure, Gross Capital Formation and Net Exports. It is observed that the maximum, entropy corresponds to a cluster which does not explicitly include the Gross Domestic Product but only the other (3) "axes", i.e. consumption, investment and trade components. On the other hand, the minimal entropy clustering scheme is obtained from a coupling necessarily including Gross Domestic Product and Final Consumption Expenditure. The results confirm intuitive economic theory and practice expectations at least as regards geographical connexions. The technique can of course be applied to many other cases in the physics of socio-economy networks. [less ▲]

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See detailMesurer la douleur chez le patient non communicant.
Chatelle, Camille ULg; Vanhaudenhuyse, Audrey ULg; Mergam, Anne-Nora ULg et al

in Revue Médicale de Liège (2008), 63(5-6), 429-37

Pain is a subjective experience. Its assessment is based on the subject's direct verbal report. This method of assessment is, however, impossible in patients who cannot communicate their feelings. In this ... [more ▼]

Pain is a subjective experience. Its assessment is based on the subject's direct verbal report. This method of assessment is, however, impossible in patients who cannot communicate their feelings. In this context, indirect measurements such as behavioral observations or physiological measurements are needed. To facilitate the assessment of pain in non-communicative patients, numerous standardized behavioral scales have been developed. The aim of this review is to discuss the main validated pain scales employed in end-stage dementia, newborn and preverbal children, and severely brain damaged patients with a disorder of consciousness such as coma, the vegetative state or the minimally conscious state. [less ▲]

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See detailMECHANICAL PRETREATMENT EFFECT ON CELLULOSE ENZYMATICAL HYDROLYSIS
Jacquet, Nicolas ULg; Paquot, Michel ULg

Poster (2008)

Lignocellulosic materials are very interesting for the production of bioethanol after chemical or enzymatical hydrolysis of cellulose. To optimise production rate and increase the output of these ... [more ▼]

Lignocellulosic materials are very interesting for the production of bioethanol after chemical or enzymatical hydrolysis of cellulose. To optimise production rate and increase the output of these processes, different kinds of pre-treatments (grinding, steam explosion…) are often needed for opening the fibrous structure of the cellulose and increase the specific surface of the materials. The present study is focused on two models of “pure” cellulose (cellulose C200 microtechnik, cellulose FD100 FMC biopolymer) in order to analyse the effects of mechanical pretreatments on the kinetics and yields of hydrolysis. The cristallinity index differentiates the two celluloses. Hydrolysis is realized by a cellulase mix (cellulase Trichoderma reesei C2730, Novozyme; cellobiase Aspergillus niger C6105). Results present the influence of homogenisation pretreatment and analyse differents parameters of this technology. [less ▲]

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See detailPouvoir et consentement : quelques réflexions impressionnistes
Jacquemain, Marc ULg

in Vrancken, Didier; Dubois, Christophe; Schoenaers, Frédéric (Eds.) Penser la négociation : mélange en hommage à Olgierd Kuty (2008)

L'article confronte deux classiques, "Power" de Steven Lukes et "L'acteur et le système" de Crozier et Friedberg, aux réflexions d'auteurs contemporains comme Beck et Negri sur la nature du pouvoir et son ... [more ▼]

L'article confronte deux classiques, "Power" de Steven Lukes et "L'acteur et le système" de Crozier et Friedberg, aux réflexions d'auteurs contemporains comme Beck et Negri sur la nature du pouvoir et son caractère "immanent". A partir de là, il présente brièvement six propositions sur la nature du pouvoir dans les sociétés démocratiques et le rôle important qu'y joue le consentement. Il termine sur "l'invisibilisation" du pouvoir dans le capitalisme contemporain. [less ▲]

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See detailDistantly related lipocalins share two conserved clusters of hydrophobic residues: use in homology modeling.
Adam, Benoit; Charloteaux, Benoît ULg; Beaufays, Jérôme ULg et al

in BMC structural biology (2008), 8(1-2), 1-18

BACKGROUND: Lipocalins are widely distributed in nature and are found in bacteria, plants, arthropoda and vertebra. In hematophagous arthropods, they are implicated in the successful accomplishment of the ... [more ▼]

BACKGROUND: Lipocalins are widely distributed in nature and are found in bacteria, plants, arthropoda and vertebra. In hematophagous arthropods, they are implicated in the successful accomplishment of the blood meal, interfering with platelet aggregation, blood coagulation and inflammation and in the transmission of disease parasites such as Trypanosoma cruzi and Borrelia burgdorferi. The pairwise sequence identity is low among this family, often below 30%, despite a well conserved tertiary structure. Under the 30% identity threshold, alignment methods do not correctly assign and align proteins. The only safe way to assign a sequence to that family is by experimental determination. However, these procedures are long and costly and cannot always be applied. A way to circumvent the experimental approach is sequence and structure analyze. To further help in that task, the residues implicated in the stabilisation of the lipocalin fold were determined. This was done by analyzing the conserved interactions for ten lipocalins having a maximum pairwise identity of 28% and various functions. RESULTS: It was determined that two hydrophobic clusters of residues are conserved by analysing the ten lipocalin structures and sequences. One cluster is internal to the barrel, involving all strands and the 310 helix. The other is external, involving four strands and the helix lying parallel to the barrel surface. These clusters are also present in RaHBP2, a unusual "outlier" lipocalin from tick Rhipicephalus appendiculatus. This information was used to assess assignment of LIR2 a protein from Ixodes ricinus and to build a 3D model that helps to predict function. FTIR data support the lipocalin fold for this protein. CONCLUSION: By sequence and structural analyzes, two conserved clusters of hydrophobic residues in interactions have been identified in lipocalins. Since the residues implicated are not conserved for function, they should provide the minimal subset necessary to confer the lipocalin fold. This information has been used to assign LIR2 to lipocalins and to investigate its structure/function relationship. This study could be applied to other protein families with low pairwise similarity, such as the structurally related fatty acid binding proteins or avidins. [less ▲]

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See detailInteractions between bacterial surfaces and milk proteins, impact on food emulsions stability
Ly, M. H.; Aguedo, Mario ULg; Goudot, S. et al

in Food Hydrocolloids (2008), 22(5), 742-751

Bacteria possess physicochemical surface properties such as hydrophobicity, Lewis acid/base and charge which are involved in physicochemical interactions between cells and interfaces. Moreover, food ... [more ▼]

Bacteria possess physicochemical surface properties such as hydrophobicity, Lewis acid/base and charge which are involved in physicochemical interactions between cells and interfaces. Moreover, food matrices are complex and heterogeneous media, with a microstructure depending on interactions between the components in media (van der Waals, electrostatic or structural forces, etc.). Despite the presence of bacteria in fermented products, few works have investigated how bacteria interact with other food components. The objective of the present study was to determine the effects of the surface properties of lactic acid bacteria on the stability of model food emulsions. The bacteria were added to oil/water emulsions stabilized by milk proteins (sodium caseinate, whey proteins concentrate or whey proteins isolate) at different pH (from 3 to 7.5). The effect of bacteria on the emulsions stability depended on the surface properties of strains and also on the characteristics of emulsions. Flocculation and aggregation phenomena were observed in emulsion at pHs for which the bacterial surface charge was opposed to the one of the proteins. The effects of bacteria on the stability of emulsion depended also on the concentration of cations present in media such as Ca2+. These results show that the bacteria through their surface properties could interact with other compounds in matrices, consequently affecting the stability of emulsions. The knowledge and choice of bacteria depending on their surface properties could be one of the important factors to control the stability of matrices such as fermentation media or fermented products. © 2007 Elsevier Ltd. All rights reserved. [less ▲]

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See detailAugustinus (Pseudo-), S., De vita christiana
Adam, Renaud ULg

in De Schepper, Marcus; Kelders, Ann; Pauwels, Jan (Eds.) In de ban van boeken. Grote verzamelaars uit de negentiende eeuw in de Koninklijke Bibliotheek van België (2008)

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See detailPius II (Aeneas Silvio Piccolomini), De duobus amantibus Euryalo et Lucretia
Adam, Renaud ULg

in De Schepper, Marcus; Kelders, Ann; Pauwels, Jan (Eds.) In de ban van boeken. Grote verzamelaars uit de negentiende eeuw in de Koninklijke Bibliotheek van België (2008)

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See detailMarco Polo, De consuetudinibus et conditionibus orientalium regionum
Adam, Renaud ULg

in De Schepper, Marcus; Kelders, Ann; Pauwels, Jan (Eds.) In de ban van boeken. Grote verzamelaars uit de negentiende eeuw in de Koninklijke Bibliotheek van België (2008)

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See detailJuan Luis Vives, Introductio ad Sapientiam. Satellitium sive Symbola. Epistolae duae de ratione studii puerilis
Adam, Renaud ULg

in De Schepper, Marcus; Kelders, Ann; Pauwels, Jan (Eds.) In de ban van boeken. Grote verzamelaars uit de negentiende eeuw in de Koninklijke Bibliotheek van België (2008)

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See detailReinhard von Solms, Eyn gesprech eynes alten erfarnen kriegssmans und bawmeysters mit eynem jungen hauptamnn
Adam, Renaud ULg

in De Schepper, Marcus; Kelders, Ann; Pauwels, Jan (Eds.) In de ban van boeken. Grote verzamelaars uit de negentiende eeuw in de Koninklijke Bibliotheek van België (2008)

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See detailJohannes Arnoldus Bergellanus, De chalcographiae inventione poema encomiasticum
Adam, Renaud ULg

in De Schepper, Marcus; Kelders, Ann; Pauwels, Jan (Eds.) In de ban van boeken. Grote verzamelaars uit de negentiende eeuw in de Koninklijke Bibliotheek van België (2008)

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See detailIL-4/IL-13 independent goblet cell hyperplasia in experimental helminth infections.
Marillier, Reece G; Michels, Chesney; Smith, Elizabeth M et al

in BMC Immunology (2008), 9

BACKGROUND: Intestinal mucus production by hyperplasic goblet cells is a striking pathological feature of many parasitic helminth infections and is related to intestinal protection and worm expulsion ... [more ▼]

BACKGROUND: Intestinal mucus production by hyperplasic goblet cells is a striking pathological feature of many parasitic helminth infections and is related to intestinal protection and worm expulsion. Induction of goblet cell hyperplasia is associated with TH2 immune responses, which in helminth infections are controlled primarily by IL-13, and also IL-4. In the study presented here we examine the goblet cell hyperplasic response to three experimental parasitic helminth infections; namely Nippostrongylus brasiliensis, Syphacia obvelata and Schistosoma mansoni. RESULTS: As expected N. brasiliensis infection induced a strong goblet cell hyperplasia dependent on IL-4/IL-13/IL-4Ralpha expression. In contrast, and despite previously published transiently elevated IL-4/IL-13 levels, S. obvelata infections did not increase goblet cell hyperplasia in the colon. Furthermore, induction of goblet cell hyperplasia in response to S. mansoni eggs traversing the intestine was equivalent between BALB/c, IL-4/IL-13-/- and IL-4Ralpha-/- mice. CONCLUSION: Together these data demonstrate that intestinal goblet cell hyperplasia can be independent of TH2 immune responses associated with parasitic helminth infections. [less ▲]

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See detailReview of June E. Roberts's Reading Erna Brodber: Uniting the Black Diaspora through Folk Culture
Ledent, Bénédicte ULg

in Nieuwe West-Indische Gids = New West Indian Guide (2008), 82(3-4), 325-327

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See detailAuthentication in stealth distributed hash tables
MacQuire, A.; Brampton, A.; Rai, I. A. et al

in Journal of Systems Architecture (2008), 54(6), 607--618

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See detailL'image du mois. Une ingestion indigeste"."
Jobe, Jérôme ULg; Brasseur, Edmond ULg; Ghuysen, Alexandre ULg et al

in Revue Médicale de Liège (2008), 63(2), 57-8

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See detailCoelogyne pulverula or Coelogyne tomentosa
Delaplace, Pierre ULg

in The Journal of the Orchid Society of Great Britain (2008), 57

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