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See detailFibrillar type I collagens enhance platelet-dependent thrombin generation via glycoprotein VI with direct support of alpha2beta1 but not alphaIIbbeta3 integrin.
Lecut, Christelle ULg; Feijge, Marion A H; Cosemans, Judith M E M et al

in Thrombosis and Haemostasis (2005), 94(1), 107-14

The role of collagens and collagen receptors was investigated in stimulating platelet-dependent thrombin generation. Fibrillar type-I collagens, including collagen from human heart, were most potent in ... [more ▼]

The role of collagens and collagen receptors was investigated in stimulating platelet-dependent thrombin generation. Fibrillar type-I collagens, including collagen from human heart, were most potent in enhancing thrombin generation, in a way dependent on exposure of phosphatidylserine (PS) at the platelet surface. Soluble, non-fibrillar type-I collagen required pre-activation of integrin alpha2beta1 with Mn2+ for enhancement of thrombin generation. With all preparations, blocking of glycoprotein VI (GPVI) with 9O12 antibody abrogated the collagen-enhanced thrombin generation, regardless of the alpha2beta 1 activation state. Blockade of alpha2beta1 alone or antagonism of autocrine thromboxane A2 and ADP were less effective. Blockade of alphaIIbbeta3 with abciximab suppressed thrombin generation in platelet-rich plasma, but this did not abolish the enhancing effect of collagens. The high activity of type-I fibrillar collagens in stimulating GPVI-dependent procoagulant activity was confirmed in whole-blood flow studies, showing that these collagens induced relatively high expression of PS. Together, these results indicate that: i) fibrillar type-I collagen greatly enhances thrombin generation, ii) GPVI-induced platelet activation is principally responsible for the procoagulant activity of fibrillar and non-fibrillar collagens, iii) alpha2beta1 and signaling via autocrine mediators facilitate and amplify this GPVI activity, and iv) alphaIIbbeta3 is not directly involved in the collagen effect. [less ▲]

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See detailLe principe de légalité en matière de roulage : un principe relatif?
Jacobs, Ann ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2005)

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See detailQue reste-t-il de l’autorité de la chose jugée du pénal sur le civil ?
Jacobs, Ann ULg

in Revue Critique de Jurisprudence Belge (2005)

Etat de la question de l'autorité de chose jugée du pénal sur le civil, en particulier en matière de roulage,la conclusion étant que cette autorité a tendance à disparaître

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See detailModélisation par éléments finis du couplage thermo-élastique dans les structures vibrantes
Lepage, Séverine; Golinval, Jean-Claude ULg

Conference given outside the academic context (2005)

Micro-accelerometers and micro-gyrometers are being developed in order to respond to the demand of accurate miniature inertial navigation systems. In the design of such accurate systems, which require a ... [more ▼]

Micro-accelerometers and micro-gyrometers are being developed in order to respond to the demand of accurate miniature inertial navigation systems. In the design of such accurate systems, which require a high quality factor, the dissipation mechanisms such as the thermoelastic damping have to be considered. In order to assess the thermoelastic influence on the behavior of vibrating structures, analytical models may be used for simple configurations under very restrictive assumptions. In order to investigate more complex structures, the finite element method may be used. An oscillating clamped-clamped beam is modelled using thermoelastic finite elements. The analytical and finite element analyses show that the thermoelastic coupling implies a natural frequency shift, an amplitude attenuation, a difference of phase between the thermal and mechanical degrees of freedom and influences the quality factor of the resonating system. [less ▲]

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See detailFault Detection Algorithm based on Null-Space Analysis for On-Line Structural Health Monitoring
Yan, Ai-Min; Golinval, Jean-Claude ULg; Marin, Frédéric

Conference given outside the academic context (2005)

Early diagnosis of structural damages or machinery malfunctions allows to reduce the maintenance cost of systems and to increase their reliability and safety. This paper addresses the damage detection ... [more ▼]

Early diagnosis of structural damages or machinery malfunctions allows to reduce the maintenance cost of systems and to increase their reliability and safety. This paper addresses the damage detection problem by statistical analysis on output-only measurements of structures. The developed method is based on subspace analysis of the Hankel matrices constructed by vibration measurement data. The column active subspace of the Hankel matrix defined by the first principal components is orthonormal to the column null-subspace defined by the remaining principal components. The residue in the orthonormality relation obtained from different data sets may be used to detect structural damages. It is illustrated that this null-space-based method constitutes an enhancement of the classical damage detection method based on principal component analysis (PCA). Several damage indicators are proposed to characterize the resulting residue matrices. The method is first illustrated on a numerical example and then, it is applied to vibration fatigue testing of a street-lighting device. Because of its simplicity and efficiency, the proposed algorithm is expected to be suitable for continuous on-line health monitoring of structures in practical situations. [less ▲]

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See detailLocal dependence estimation using semi-parametric Archimedean copulas
Vandenhende, François; Lambert, Philippe ULg

in Canadian Journal of Statistics = Revue Canadienne de Statistique (2005), 33

The authors de¯ne a new semiparametric Archimedean copula family having a °exible depen- dence structure. The family's generator is a local interpolation of existing generators. It has locally-de¯ned ... [more ▼]

The authors de¯ne a new semiparametric Archimedean copula family having a °exible depen- dence structure. The family's generator is a local interpolation of existing generators. It has locally-de¯ned dependence parameters. The authors present a penalized constrained least-squares method to estimate and smooth these parameters. They illustrate the °exibility of their dependence model in a bivariate survival example. [less ▲]

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See detailConstraints on concordance measures in bivariate discrete data
Denuit, Michel; Lambert, Philippe ULg

in Journal of Multivariate Analysis (2005), 93

This paper aims to investigate the constraints on dependence measures based on the concept of concordance when discrete random variables are involved. The main technical argument consists in a continuous ... [more ▼]

This paper aims to investigate the constraints on dependence measures based on the concept of concordance when discrete random variables are involved. The main technical argument consists in a continuous extension of integer-valued random variables by convolution with unit support kernels [less ▲]

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See detailApplicability of models in the field of environmental chemistry of the Med Sea
Beckers, Jean-Marie ULg

in Saliot, Alain (Ed.) The Mediterranean Sea (2005)

The present chapter highlights the problems facing when modelling the marine environment, in particular for biochemical aspects. It is shown how the marine environment differs from other fluids and how ... [more ▼]

The present chapter highlights the problems facing when modelling the marine environment, in particular for biochemical aspects. It is shown how the marine environment differs from other fluids and how this affects modelling. General modelling approaches are shown and the problem of the vaste range of scales encountered is adressed. In addition to mathematical modelling problems, practical questions of adequate boundary and initial conditions are then further analysed with respect to biochemical components carried by the flow. Finally questions of errors, validation and data assimilation encountered during the analysis of the model’s quality are adressed. [less ▲]

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See detailLe rôle des promotions foncières et immobilières dans la production des périphéries : application à la Belgique et à ses nouveaux espaces résidentiels
Halleux, Jean-Marie ULg

in Revue Géographique de l'Est (2005), (3-4), 161-174

Despite their spatial and economic importances, the sectors of property and land developments are still badly known. The aim of this article, dedicated to the spatial context of new residential ... [more ▼]

Despite their spatial and economic importances, the sectors of property and land developments are still badly known. The aim of this article, dedicated to the spatial context of new residential developments produced in Belgium, is to analyse the influence of those sectors on both, the urban land-uses and the characteristics of residential outskirts. In the first part, the analysed spatial context is presented. In the second part, dedicated to the investment choices of land developers, we try to apprehend why the Belgian peri-urbanisation engenders very important land consumptions. In the third part, the property development issue is taken into account in order to explain why the self-provided sector is so highly prevailing in Belgium. Our research leads to the conclusion that investment choices of both, land developers and property developers, are highly constrained by land market configurations. [less ▲]

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See detailSeparation and identification of endoxylanases from Bacillus subtilis and their actions on wheat bran insoluble dietary fibre
Xiaoping, Yuan; Jing, Wang; Huiyuan, Yao et al

in Process Biochemistry (2005), 40(7), 2339-2343

A novel and convenient method based on native polyacrylamide gel electrophoresis (PAGE) and homogenization extraction was used for the purification of xylanase from crude enzymes. Two xylanases were ... [more ▼]

A novel and convenient method based on native polyacrylamide gel electrophoresis (PAGE) and homogenization extraction was used for the purification of xylanase from crude enzymes. Two xylanases were purified by this method from the crude enzyme preparation from the selected strain of Bacillus subtilis. Subsequent analysis with thin layer chromatography and high pressure liquid chromatography (HPLC) indicated that these two xylanases were endo-acting enzymes, designated xyl I and xyl II. Both enzymes showed their activities in the pH range from 5.0 to 9.0 at 50 °C and had similar optimum activities at pH 7.0 and at 50 °C. Mn2+ ions enhanced their xylanolytic activities to 2.7-fold whereas Fe3+ completely inhibited them. The action of endoxylanase xyl II on wheat bran insoluble dietary fibre was also studied. The hydrolysis products were shown to contain feruloyl oligosaccharides by paper chromatography [less ▲]

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See detailL'hypersensibilité à l'électricité: une approche multidisciplinaire pour un problème multifactoriel. Revue de la littérature
Crasson, Marion ULg

in European Review of Applied Psychology = Revue Européenne de Psychologie Appliquée (2005), 55

L’hypersensibilité à l’électricité (HE) est un syndrome essentiellement défini par le patient lui-même, lequel présente des plaintes qu’il attribue à l’usage ou à la proximité d’appareils ou d’équipements ... [more ▼]

L’hypersensibilité à l’électricité (HE) est un syndrome essentiellement défini par le patient lui-même, lequel présente des plaintes qu’il attribue à l’usage ou à la proximité d’appareils ou d’équipements émettant des champs électriques (CE), magnétiques (CM) ou électromagnétiques (CEM). La plupart des recherches, scandinaves, indiquent des plaintes dermatologiques chez des travailleurs sur écran mais de plus en plus de personnes se plaignent d’un syndrome plus général de type neurasthénique qui s’étend à d’autres sources de rayonnements nonionisants, lignes à haute tension et systèmes de mobilophonie. Ce terme n’implique pas de relation démontrée entre l’exposition aux champs électromagnétiques et les symptômes rapportés, comme l’indiquent les études de provocation. L’origine de l’hypersensibilité à l’électricité serait davantage multifactorielle et invite à la prise en considération multidisciplinaire de facteurs environnementaux, biologiques, psychologiques et psychosociaux dans le diagnostic et le traitement de ce syndrome hétérogène. Le but de cet article est de donner un aperçu des connaissances actuelles et des hypothèses étiologiques destinées à mieux comprendre et mieux aider les personnes qui en souffrent. [less ▲]

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See detailOptimisation of hydroelectric power stations operations with WOLF package
Erpicum, Sébastien ULg; Archambeau, Pierre ULg; Dewals, Benjamin ULg et al

in Repp, K.; Westeren, T.; Sandlund, O. T. (Eds.) et al Proceedings of the 5th International Conference on Hydropower - The backbone of sustainable energy supply (2005)

For years, original free-surface flow solvers have been developed and continuously improved by the Laboratory of Applied Hydrodynamics and Hydraulic Constructions (HACH) at the University of Liège. The ... [more ▼]

For years, original free-surface flow solvers have been developed and continuously improved by the Laboratory of Applied Hydrodynamics and Hydraulic Constructions (HACH) at the University of Liège. The resulting fully integrated WOLF computation package allows engineers to accurately study a very wide range of various free surface flows, from hydrological runoff (WOLF HYDRO) and river propagation (WOLF 1D) to extreme erosive flows on realistic mobile topography (WOLF 2D), such as gradual dam breaching processes. All the finite volume models, process oriented, use efficient and original numerical methods to solve free surface flows equations. Each code handles general multiblock meshes, dealing with natural topography, dry and wet cells and mobile bed simultaneously, for any unsteady situation with mixed regimes and moving hydraulic jumps. The interactive and unique user-interface, with high performance pre- and post-processing, allows monitoring 3-D large-scale runs graphically while they proceed, as well as generating 3D videos. In addition, powerful optimisation capabilities based on the Genetic Algorithms technique (WOLF AG) are implemented within WOLF, interconnecting all the package components. An efficient tool is thus available to calibrate physical parameters in any of the models and to manage any problem of optimisation with the different solvers. In this paper, the numerical optimisation process of the system of hydroelectric power stations installed on a 60 km long section of the rivers Amblève and Warche in Belgium is presented in detail. The river network is modelled in quasi-2D using real natural topographic data on almost 1,100 finite volumes. In a first step, the hydrological balance is closed using the solver WOLF HYDRO. Roughness coefficients are calibrated from water level and discharge field measurements. Secondly, the hydroelectric production is maximised by an automatic calibration of the parameters of the hydrograph released in the network at the upstream dam. This approach leads to a substantial gain in hydroelectric production, brings significant financial benefits and deals with all management and security criteria of the river network. [less ▲]

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See detailNumerical tools for the optimization of hydroelectric power stations in cascade
Erpicum, Sébastien ULg; Archambeau, Pierre ULg; Dewals, Benjamin ULg et al

in Dick, Erik; Hogge, Michel; Van Keer, Roger (Eds.) Proceedings of the 3rd Internationale Conference on Advanced Computational Methods in Engineering (2005)

The numerical optimization process of the system of hydroelectric power stations installed on a 60 km long section of the rivers Amblève and Warche in Belgium is presented in detail. The river network is ... [more ▼]

The numerical optimization process of the system of hydroelectric power stations installed on a 60 km long section of the rivers Amblève and Warche in Belgium is presented in detail. The river network is modelled in quasi-2D using real natural topographic data on almost 1,100 finite volumes. In a first step, the hydrological balance is closed using a numerical solver and roughness coefficients are calibrated from water level and discharge field measurements. Secondly, the hydroelectric production is maximised by an automatic calibration of the parameters of the hydrograph released in the network at the upstream dam. This approach leads to a substantial gain in hydroelectric production, brings significant financial benefits and deals with all management and security criteria of the river network. [less ▲]

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See detailImmunolgic response to (pre)neoplastic cervical lesions associated with human papillomavirus
Delvenne, Philippe ULg

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (2005), 160(5-6), 287-93

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See detailLe "classroom Assessment" dans l'enseignment supérieur : Diagnostiquer des faiblesses dans son enseignement
Poumay, Marianne ULg

Learning material (2005)

A l’origine de la professionnalisation de l’enseignement et de l’apprentissage, le courant de l’évaluation de classe (en anglais « classroom assessment ») est une composante d’un autre courant, celui de ... [more ▼]

A l’origine de la professionnalisation de l’enseignement et de l’apprentissage, le courant de l’évaluation de classe (en anglais « classroom assessment ») est une composante d’un autre courant, celui de la recherche en classe, né aux Etats-Unis au début des années 1990. Il a pour but d’aider les enseignants du supérieur à mieux comprendre ce que les étudiants apprennent à leur cours et avec quelle qualité ils apprennent. La recherche en classe pousse les enseignants à tenter de mieux comprendre les processus d’apprentissage en oeuvre chez leurs étudiants et à isoler les facteurs sur lesquels leur enseignement peut avoir une influence. [less ▲]

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