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See detailIntérêt des anticorps monoclonaux dans le laboratoire d'analyses biomédicales
Mistretta, Virginie ULg; Cavalier, Etienne ULg; Collette, Julien ULg et al

in Revue Médicale de Liège (2009), 64(5-6), 257-263

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See detailDéveloppement d’une stratégie d’immunisation passive du poulet de chair vis-à-vis de Salmonella Enteritidis et Typhimurium à l’aide d’anticorps du jaune d’œuf
Marcq, Christopher ULg; Chalghoumi, RAJA ULg; Beckers, Yves ULg et al

in 8èmes JRA : Synthèses et textes (2009)

The present study investigates the potential of oral immunotherapy using hen egg yolk immunoglobulins (IgY) as a strategy to reduce the impact of Salmonella contamination on broilers. In a first step ... [more ▼]

The present study investigates the potential of oral immunotherapy using hen egg yolk immunoglobulins (IgY) as a strategy to reduce the impact of Salmonella contamination on broilers. In a first step, hyperimmune eggs were obtained from laying hens immunized using Salmonella Enteritidis (SE) and Typhimurium (ST) outer membrane proteins in emulsion with Freund adjuvants. This led to the production of high levels of IgY antibodies directed against the two Salmonella serovars in egg yolks. Furthermore, no adverse affects were detected on mortality or laying rate in hens injected with this vaccine. Powders were obtained from these eggs by spray- or freeze-drying the whole yolk. In order to study the effect of these powders on broiler’s growth performances, a challenge trial was conducted. 384 Salmonella spp.-free day-of-hatch chickens received supplemented feed (5 % freeze-dried egg yolk powder) since arrival, and were infected at day four with 106 cfu of SE and ST per animal. We found a significant improvement in growth performances for the groups receiving the yolk-enriched diets. Nevertheless, none of the supplement concentrations allowed to raise the same body weight after 28 days of complementation than in uninfected broilers (p < 0,05). Interestingly, nonimmune egg yolk powder also exhibited a positive effect on performances of broilers experimentally infected with SE and ST. Our results suggest that passive immunization through egg yolk powders could be useful to reduce negative effects of Salmonella infection on broilers growth performances. [less ▲]

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See detailMullite coatings on ceramic substrates: Stabilisation of Al2O3-SiO2 suspensions for spray drying of composite granules suitable for reactive plasma spraying
Schrijnemakers, Audrey ULg; Andre, Sophie; Lumay, Geoffroy ULg et al

in Journal of the European Ceramic Society (2009), 29(11), 2169-2175

The present work deals with the preparation of stable alumina + silica suspensions with high solid loading for the production of spray-dried composite powders. These composite powders are to be used for ... [more ▼]

The present work deals with the preparation of stable alumina + silica suspensions with high solid loading for the production of spray-dried composite powders. These composite powders are to be used for reactive plasma spraying whereby the formation of mullite and the coating on a ceramic substrate are achieved in a single step process. Electrostatic stabilisation of alumina and silica suspensions has been studied as a function of pH. Silica suspensions are most stable at basic pH whereas alumina suspensions are stable at acidic pH. The addition of ammonium polymethacrylate (APMA) makes it possible to stabilise alumina and prepare a stable 50 wt% alumina + silica suspension at pH 10. The optimum amounts of dispersant and binder have been determined by zeta potential, viscosity and sedimentation measurements. Spray drying of the suspension yields composite powders whose morphology, size distribution and flowability have been characterized before realizing reactive plasma spraying tests. (C) 2009 Elsevier Ltd. All fights reserved. [less ▲]

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See detail"Mnemosyne" et le "Denkraum" renaissant. Pratique du document visuel chez Aby Warburg
Hagelstein, Maud ULg

in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (2009), 2

L’historien de l’art juif allemand Aby Warburg (1866-1929) a marqué de manière décisive toute une génération de théoriciens de l’art du xxe siècle. Relativement discrète, son oeuvre prend toute son ... [more ▼]

L’historien de l’art juif allemand Aby Warburg (1866-1929) a marqué de manière décisive toute une génération de théoriciens de l’art du xxe siècle. Relativement discrète, son oeuvre prend toute son ampleur lorsqu’elle est envisagée du point de vue de l’épistémologie de l’histoire de l’art. En effet, Warburg s’est distingué par ses nombreuses audaces méthodologiques : son sens désarmant du détail, sa bibliothèque — dont le classement thématique défiait toute systématicité —, ses propositions inaugurales pour l’iconologie, sa désinvolture à l’égard des frontières disciplinaires. Son dernier projet (inachevé), l’atlas d’images Mnemosyne, rassemble tous ces points. L’Atlas témoigne, par ailleurs, d’une pratique du document visuel inédite pour l’époque, où le matériau iconographique, révélé par de subtils montages, fait surgir de nouveaux problèmes théoriques. Afin d’en dégager toute l’originalité, on aura ici recours aux principes exposés par Foucault dans L’archéologie du savoir (1969). [less ▲]

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See detailQuantitative methods for food allergens: a review.
Kirsch, Stéphanie ULg; Fourdrilis, Séverine ULg; Dobson, Rowan ULg et al

in Analytical and Bioanalytical Chemistry (2009), 395

The quantitative detection of allergens in the food chain is a strategic health objective as the prevalence of allergy continues to rise. Food allergenicity is caused by proteins either in their native ... [more ▼]

The quantitative detection of allergens in the food chain is a strategic health objective as the prevalence of allergy continues to rise. Food allergenicity is caused by proteins either in their native form or in forms resulting from food processing. Progress in mass spectrometry greatly opened up the field of proteomics. These advances are now available for the detection and the quantification of traces of allergenic proteins in complex mixtures, and complete the set of biological tests used until now, such as ELISA or PCR. We review methods classified according to their ability to simultaneously quantify and identify allergenic proteins and underline major advances in the mass-spectrometric methods. [less ▲]

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See detailFactors influencing microbiological and chemical composition of South-Belgian raw sludge
Guillemet, Thibault A.; Maesen, Philippe ULg; Delcarte, Emile et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2009), 13(2), 249-255

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See detailMyocardial contractile reserve during exercise predicts left ventricular reserve remodelling after cardiac resynchromization therapy
Lancellotti, Patrizio ULg; Senechal, Mario; Moonen, Marie ULg et al

in European Journal of Echocardiography (2009), 10(5), 663-8

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See detailMario Vargas Llosa y la ficción del indigenismo
Vanden Berghe, Kristine ULg

in Houvenaghel, Eugenia; Logie, Ilse (Eds.) Alianzas entre historia y ficción. Homenaje a Patrick Collard (2009)

En numerosas novelas, Vargas Llosa aborda los mismo temas que en sus ensayos de manera que se establecen ecos entre ficción y no ficción, ecos que, de una u otra manera, apoyan implícitamente la verdad de ... [more ▼]

En numerosas novelas, Vargas Llosa aborda los mismo temas que en sus ensayos de manera que se establecen ecos entre ficción y no ficción, ecos que, de una u otra manera, apoyan implícitamente la verdad de los textos literarios por la de los ensayos historiográficos. También el hecho de que el narrador en sus novelas a menudo tenga rasgos autobiográficos evidentes de su autor contribuye a borrar las fronteras entre universo de ficción interno y universo externo. Además, en varias novelas Vargas Llosa tiende a borrar las fronteras entre los géneros, y acerca la novela al ensayo Al comparar El hablador, novela que publicó en 1987, con el ensayo José María Arguedas o las ficciones del indigenismo, de 1996, nos interrogamos acerca de la relación que existe entre las ideas sobre el indigenismo expresadas por Vargas Llosa en la ficción y fuera de ella. [less ▲]

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See detailSurfology: concrete substrate evaluation prior to repair
Courard, Luc ULg; Michel, Frédéric ULg; Schwall, Damien ULg et al

in Mammoli, A.; Brebbia, C. A. (Eds.) Materials Characterization: computational methods and experiments IV (2009)

The study of adhesion of repair materials on concrete structures implies a good knowledge of the influence of concrete surface treatment. The effects of surface preparation technique are rarely clearly ... [more ▼]

The study of adhesion of repair materials on concrete structures implies a good knowledge of the influence of concrete surface treatment. The effects of surface preparation technique are rarely clearly described and parameterised: it is consequently difficult to point out the real influence of roughness on adhesion results. A large research project has been realized with regards to the influence of concrete substrate strength and preparation technique efficiency. The surface roughness of concrete has been quantified by means of the projection “Moiré” technique, which is an interferometrical measurement method. Comparison between polished, scrabbled and hydro-jetted surfaces evaluation is presented. [less ▲]

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See detailLa neuropathie autonome: une complication méconnue du diabète
Philips, Jean-Christophe ULg; Marchand, Monique; Scheen, André ULg

in Association belge du diabète (2009), 52(1), 24-29

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See detailL'etude UPLIFT (Understanding Potential Long-term Impacts on Function with Tiotropium).
Corhay, Jean-Louis ULg; Louis, Renaud ULg

in Revue Médicale de Liège (2009), 64(1), 52-7

The UPLIFT study (Understanding Potential Long-term Impacts on Function with Tiotropium) was a double-blind, randomised, international, multicentric, placebo-controlled clinical trial, investigating with ... [more ▼]

The UPLIFT study (Understanding Potential Long-term Impacts on Function with Tiotropium) was a double-blind, randomised, international, multicentric, placebo-controlled clinical trial, investigating with tiotropium (Spiriva) the change in the annual rate of decline in FEV1 in chronic obstructive pulmonary disease (COPD). Secondary end points included COPD exacerbation rate with or without hospitalisation, lung function, quality of life and mortality. 5.993 patients were randomized. In this article, we briefly describe the most important results of the study. While tiotropium did not alter the annual rate of decline in FEV1 (pre and postbronchodilatation), it improved lung function and quality of life, and reduced exacerbations and hospitalisations by comparison with control for up to 4 years. Tiotropium also reduced respiratory and cardiac morbidity. [less ▲]

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See detailPenser le combat ordinaire : plonger dans la chair sociologique du monde
Frère, Bruno ULg

in Hermès (2009), 54

Il va en quelque sorte s'agir, dans ce texte, de montrer comment, parce qu'elle donne à voir le mouvement d'une pensée tant pratique (les dessins) que théorique (les textes) qui s'interroge à la fois sur ... [more ▼]

Il va en quelque sorte s'agir, dans ce texte, de montrer comment, parce qu'elle donne à voir le mouvement d'une pensée tant pratique (les dessins) que théorique (les textes) qui s'interroge à la fois sur le monde social, sur le phénomène politique et sur le phénomène artistique, la complexité de la bande dessinée peut se laisser décanter par la philosophie. C'est donc en fin de compte bel et bien à son rôle originaire de techné (de « technique » selon Aristote), d'outil, que sera renvoyé la philosophie dans ce court article consacré aux albums de Manu Larcenet : le combat ordinaire [less ▲]

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See detailDesde las montañas del sureste
Vanden Berghe, Kristine ULg

in González Boixo, José Carlos (Ed.) Tendencias de la narrativa mexicana actual (2009)

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See detailOn the derivation of the Dirac equation
Sartor, Renato ULg

E-print/Working paper (2009)

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See detailDo pictures of faces, and which ones, capture attention in the inattentional blindness paradigm?
Devue, Christel ULg; Laloyaux, Cédric ULg; Feyers, Dorothée ULg et al

in Perception (2009), 38(4), 552568

Faces and self-referential materials (eg the own name) are more likely to capture attention in the inattentional blindness (IB) paradigm than others stimuli. This effect is presumably due to the meaning ... [more ▼]

Faces and self-referential materials (eg the own name) are more likely to capture attention in the inattentional blindness (IB) paradigm than others stimuli. This effect is presumably due to the meaning of these stimuli rather than to their familiarity (Mack and Rock 1998). IB has mostly been investigated with schematic stimuli in previous work. In the present study, the generalisability of this finding was tested using photographic stimuli. In support to the view that faces constitute a special category of stimuli, it was found that pictures of faces resisted more to IB than pictures of common objects (Experiment 1) or than pictures of inverted faces (Experiment 2). In a third experiment, the influence of face familiarity and identity (ie the participant’s own face, a friend’s face and an unknown face) on IB rates was evaluated. Unexpectedly, no differential resistance to blindness across these three kinds of faces was found. In conclusion, picture of faces attracted attention more than pictures of objects or inverted faces in the IB paradigm. However, this effect was not dependent on face familiarity or identity. [less ▲]

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See detailRandom matrix model for antiferromagnetism and superconductivity on a two-dimensional lattice
Vanderheyden, Benoît ULg; Jackson, A. D.

in Physical Review B (Condensed Matter and Materials Physics) (2009), 79(14), 144502

We suggest a new mean-field method for studying the thermodynamic competition between magnetic and superconducting phases in a two-dimensional square lattice. A partition function is constructed by ... [more ▼]

We suggest a new mean-field method for studying the thermodynamic competition between magnetic and superconducting phases in a two-dimensional square lattice. A partition function is constructed by writing microscopic interactions that describe the exchange of density and spin fluctuations. A block structure dictated by spin, time-reversal, and bipartite symmetries is imposed on the single-particle Hamiltonian. The detailed dynamics of the interactions are neglected and replaced by a normal distribution of random matrix elements. The resulting partition function can be calculated exactly. The thermodynamic potential has a structure which depends only on the spectrum of quasiparticles propagating in fixed condensation fields, with coupling constants that can be related directly to the variances of the microscopic processes. The resulting phase diagram reveals a fixed number of phase topologies whose realizations depend on a single coupling parameter ratio, alpha. Most phase topologies are realized for a broad range of values of alpha and can thus be considered robust with respect to moderate variations in the detailed description of the underlying interactions. [less ▲]

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See detailSafety and efficacy of tibolone in breast cancer patients with vasomotor symptoms : a double-blind, randomised non inferiority tria
Kenemans, P.; Bundred, N. J.; Foidart, Jean-Michel ULg et al

in Lancet Oncology (2009), 10(2), 135-46

Background Vasomotor symptoms and bone loss are complications frequently induced by adjuvant treatment for breast cancer. Tibolone prevents both side-effects, but its effect on cancer recurrence is ... [more ▼]

Background Vasomotor symptoms and bone loss are complications frequently induced by adjuvant treatment for breast cancer. Tibolone prevents both side-effects, but its effect on cancer recurrence is unknown. The aim of this study was to show non-inferiority of tibolone to placebo regarding risk of recurrence in breast-cancer patients with climacteric complaints. Methods Between July 11, 2002, and Dec 20, 2004, women surgically treated for a histologically confirmed breast cancer (T1–3N0–2M0) with vasomotor symptoms were randomly assigned to either tibolone 2·5 mg daily or placebo at 245 centres in 31 countries. Randomisation was done by use of a centralised interactive voice response system, stratified by centre, with a block size of four. The primary endpoint was breast-cancer recurrence, including contralateral breast cancer, and was analysed in the intention-to-treat (ITT) and per-protocol populations; the margin for non-inferiority was set as a hazard ratio of 1·278. This study is registered with ClinicalTrials.gov, number NCT00408863. Findings Of the 3148 women randomised, 3098 were included in the ITT analysis (1556 in the tibolone group and 1542 in the placebo group). Mean age at randomisation was 52·7 years (SD 7·3) and mean time since surgery was 2·1 years (SD 1·3). 1792 of 3098 (58%) women were node positive and 2185 of 3098 (71%) were oestrogen-receptor positive. At study entry, 2068 of 3098 (67%) women used tamoxifen and 202 of 3098 (6·5%) women used aromatase inhibitors. The mean daily number of hot flushes was 6·4 (SD 5·1). After a median follow-up of 3·1 years (range 0·01–4·99), 237 of 1556 (15·2%) women on tibolone had a cancer recurrence, compared with 165 of 1542 (10·7%) on placebo (HR 1·40 [95% CI 1·14–1·70]; p=0·001). Results in the per-protocol population were similar (209 of 1254 [16·7%] women in the tibolone group had a recurrence vs 138 of 1213 [11·4%] women in the placebo group; HR 1·44 [95% CI 1·16–1·79]; p=0·0009). Tibolone was not different from placebo with regard to other safety outcomes, such as mortality (72 patients vs 63 patients, respectively), cardiovascular events (14 vs 10, respectively), or gynaecological cancers (10 vs 10, respectively). Vasomotor symptoms and bone-mineral density improved significantly with tibolone, compared with placebo. [less ▲]

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See detailGynaecological uses of a new class of steroids: the selective progesterone receptor modulators
Pintiaux, Axelle ULg; Chabbert-Buffet, N.; Foidart, Jean-Michel ULg

in Gynecological Endocrinology : The Official Journal of the International Society of Gynecological Endocrinology (2009), 25(2), 67-73

Selective progesterone receptor modulators (SPRM) represent a new class of synthetic steroids, which can interact with the progesterone receptor (PR) and can exert agonist, antagonist or mixed effects on ... [more ▼]

Selective progesterone receptor modulators (SPRM) represent a new class of synthetic steroids, which can interact with the progesterone receptor (PR) and can exert agonist, antagonist or mixed effects on various progesterone target tissues in vivo. This review evaluates the actual and potential usefulness of SPRMs in gynaecology [less ▲]

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See detailDifferential elevation of matrix metalloproteinase expression in women exposed to levonorgestrel-releasing intrauterine system for a short or prolonged period of time
Labied, Soraya ULg; Galant, C.; Nisolle, Michelle ULg et al

in Human Reproduction (2009), 24(1), 113-121

BACKGROUND: The levonorgestrel-releasing intrauterine system (LNG-IUS) is an effective contraceptive and has many non-contraceptive health benefits. However, it is commonly associated with irregular ... [more ▼]

BACKGROUND: The levonorgestrel-releasing intrauterine system (LNG-IUS) is an effective contraceptive and has many non-contraceptive health benefits. However, it is commonly associated with irregular endometrial bleeding. Metalloproteinases contribute to extracellular matrix (ECM) remodelling and regulate bleeding during the menstrual cycle. Enhanced metalloproteinase expression participates in the pathogenesis of breakthrough bleeding. Thus the objective of this study was to compare matrix metalloproteinase (MMP) expression in endometrium during luteal phase and in short-term (1 month) and long-term (> or =6 months) LNG-IUS users. METHODS: MMP expression was analysed by semi-quantitative RT-PCR and immunohistochemistry. Gelatinase activity was determined by gelatin zymography. RESULTS: MMP-1, -2, -3, -7, -9 and -12 mRNAs levels were increased, whereas that of MMP-26 was decreased in the endometrium of LNG-IUS users. MMP-1, -2, -3, -7 and -9 were localized by immunohistochemistry in all biopsies in the short-term group but in only 0-27% in the control group. The incidence of positive immunostaining for MMP-2 and -3 decreased significantly in the long-term compared with short-term LNG-IUS users. MMP-26 was localized in all biopsies from the control group but in only 14 and 25% from the short- and long-term LNG-IUS groups, respectively. In both LNG groups, the numbers of macrophages (the major source of MMP-12) was increased. CONCLUSIONS: MMP-1, active MMP-2, MMP-3, MMP-7, MMP-9 and MMP-12 are more prevalent in the short-term LNG-IUS group, suggesting their important contribution to ECM breakdown and transient bleeding. The decrease in the percentage of women expressing MMP-2 and -3 might contribute to the decreased occurrence of unwanted spotting and bleeding in long-term LNG-IUS users. [less ▲]

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See detailMagnetotransport of La0.5Ba0.5MnO3
Pekala, Marek; Drozd, V.; Fagnard, Jean-François ULg et al

in Journal of Applied Physics (2009), 105(1), 013923-013923-8

Physical properties of polycrystalline La0.5Ba0.5MnO3 are reported from low temperature (10 K) up to above room temperature. An aim has been to obtain microscopic parameters and to search for the ... [more ▼]

Physical properties of polycrystalline La0.5Ba0.5MnO3 are reported from low temperature (10 K) up to above room temperature. An aim has been to obtain microscopic parameters and to search for the characteristic lengths in terms of which one can discuss the interplay between magnetic, electric, and phonon excitations. The structural and magnetotransport measurements reveal a set of relatively high transition temperatures (near 300 K) between ferromagnetic/metallic and paramagnetic/semiconducting phases. It is found, in particular, that the so-called localization length increases from 0.085 to 0.24 nm when the magnetic field varies from 0 to 8 T. Moreover a “special field value” ~0.03 T is observed in the description of the electrical resistance. It cannot be presently distinguished whether it is the signature of a spin reorientation transition in the canted phase or a mere saturation field for aligning magnetic domains. The relatively high magnetoresistance effect (~=55% at 8 T and 10 K) makes the La0.5Ba0.5MnO3 a very interesting material for among others sensor applications. [less ▲]

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