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See detailBesoins et offre sociale et sanitaire au travers d'une approche globale et territoriale (thème 3.3)
Hanson, Sophie; Decoster, Dominique-Paule; Michel, Quentin ULg

Report (2005)

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See detailCompte-rendu de l'ouvrage de L. Bricault, "Isis en Occident"
Veymiers, Richard ULg

in Kernos : Revue Internationale et Pluridisciplinaire de Religion Grecque (2005), 18

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See detailLa gestion de l’emploi dans les centres d’appels : vers une réconciliation des intérêts du client et du travailleur ?
Naedenoen, Frédéric ULg; Rorive, Brigitte

Conference (2005, September)

Colloque - Répondre à la question de la conciliation des intérêts économiques et sociaux dans les centres d’appels ne peut se faire sans prendre en considération l’extrême hétérogénéité du secteur et des ... [more ▼]

Colloque - Répondre à la question de la conciliation des intérêts économiques et sociaux dans les centres d’appels ne peut se faire sans prendre en considération l’extrême hétérogénéité du secteur et des entreprises qui le composent. Souvent dénoncé pour la dégradation des conditions d’emploi et de travail qu’il entraîne, ce secteur d’activité est pourtant loin de répondre à une seule et même logique dans la gestion de l’emploi. Des études de cas diversifiées selon deux axes, le niveau de valeur ajoutée des services offerts par le centre d’appels, et sa complexité organisationnelle, laissent émerger des logiques différentes, influencées par la position de l’entreprise étudiée sur ces deux axes. Elles montrent l’existence d’un lien entre la configuration prise par la relation d’affaires qui unit le centre d’appels à ses clients ou donneurs d’ordres, et la politique interne de gestion de l’emploi. Ce lien n’est pas sans effet sur l’extrême difficulté à concilier les intérêts des travailleurs avec ceux des clients, particulièrement lorsque ces derniers interviennent lourdement dans la gestion interne du centre d’appels, ou en conditionnent fortement le fonctionnement par des exigences contractuelles. [less ▲]

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See detailApplication of the Lempel-Ziv complexity to the alignment-free sequence comparison of protein families
Bacha, Sofiène; Baurain, Denis ULg

Scientific conference (2005, August 26)

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See detailSynoviocytes, not chondrocytes, release free radicals after cycles of anoxia/re-oxygenation
Schneider, Nicole ULg; Mouithys-Mickalad, Ange ULg; Lejeune, Jean-Philippe ULg et al

in Biochemical & Biophysical Research Communications (2005), 334(2), 669-673

By oxymetry and electron paramagnetic resonance (EPR), we investigated the effects of repeated anoxia/re-oxygenation (A/R) periods on the respiration and production of free radicals by synoviocytes ... [more ▼]

By oxymetry and electron paramagnetic resonance (EPR), we investigated the effects of repeated anoxia/re-oxygenation (A/R) periods on the respiration and production of free radicals by synoviocytes (rabbit HIG-82 cell line and primary equine synoviocytes) and equine articular chondrocytes. Three periods of 20 min anoxia followed by re-oxygenation were applied to 10(7)cells; O(2) consumption was measured before anoxia and after each re-oxygenation. After the last A/R, cellular free radical formation was investigated by EPR spectroscopy with spin trapping technique (n=3 for each cell line). Both types of synoviocytes showed a high O(2) consumption, which was slowered after anoxia. By EPR with the spin trap POBN, we proved a free radical formation. Results were similar for equine and rabbit synoviocytes. For chondrocytes, we observed a low O(2) consumption, unchanged by anoxia, and no free radical production. These observations suggest an oxidant activity of synoviocytes, potentially important for the onset of osteoarthritis. [less ▲]

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See detailLe point sur les nouvelles insulines
Philips, J. C.; Radermecker, Régis ULg

in Revue Médicale Suisse (2005), 1(30), 1936-81940-1

It is well known that the optimal management of diabetes mellitus requires the use of various insulin formulations with complementary pharmacokinetics, in order to better mimic physiological (basal and ... [more ▼]

It is well known that the optimal management of diabetes mellitus requires the use of various insulin formulations with complementary pharmacokinetics, in order to better mimic physiological (basal and postprandial) insulin secretion. Recent advances led to the production of insulin analogues thanks to the substitution of specific amino acids. Pharmacokinetics is improved, without affecting pharmacodynamics or increasing side-effects. These new insulin forms concern both so-called ultra-short insulin analogues and long-acting insulin analogues (basal insulin). Even if they are not able to dramatically lower glycated haemoglobin levels, these new insulins significantly reduce the risk of hypoglycaemia and offer some practical advantages that could improve the quality of life of diabetic patients. [less ▲]

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See detailNouveautés dans la prise en charge médicale des anomalies du bilan phosphocalcique chez le patient hémodialysé
Van Overmeire, Lionel ULg; Delanaye, Pierre ULg; Krzesinski, Jean-Marie ULg

in Revue Médicale Suisse (2005), 1(30), 1960-5

Bone metabolism is very frequently disturbed in end stage renal failure hemodialyzed, with secondary hyperparathyroidism development but also serious potential cardiovascular consequences. New treatments ... [more ▼]

Bone metabolism is very frequently disturbed in end stage renal failure hemodialyzed, with secondary hyperparathyroidism development but also serious potential cardiovascular consequences. New treatments will be available very soon in Europe such as new phosphate binders, vitamin D2 analogues or calcimimetics to fight against such medical diseases, with the hope of less risk for vascular complications. The real place of such new medical opportunities needs to be determined. Moreover, studies with morbidity and mortality end-points are waited before estimating the real importance of these new therapeutic tools. [less ▲]

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See detailLa conceptualisation dans la démarche inductive. Les ficelles de Becker.
Semal, Nathalie ULg

Conference (2005, August 24)

How can the advice of the famous interactionnist sociologist Howard Becker be helpful to build a research project? A novice researcher vision.

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See detailLe tiotropium: une nouvelle option therapeutique dans la bronchopneumopathie chronique obstructive
Corhay, Jean-Louis ULg; Louis, Renaud ULg

in Revue Médicale Suisse (2005), 1(30), 1967-1972

Tiotropium is a long-acting anticholinergic bronchodilator, inhaled only once a day, which produces relaxation of airway smooth muscle through antagonism of acetylcholine at M3-muscarinic receptors. Its ... [more ▼]

Tiotropium is a long-acting anticholinergic bronchodilator, inhaled only once a day, which produces relaxation of airway smooth muscle through antagonism of acetylcholine at M3-muscarinic receptors. Its duration of action is at least 24 h with once daily administration of tiotropium. Several studies have shown its efficacy and its good tolerance in the treatment of patients who are suffering from moderate to very severe chronic obstructive pulmonary disease (COPD). Tiotropium improves spirometric measurements and quality of life, and reduces dyspnea and exacerbation rate in COPD patients. [less ▲]

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See detailGeographical variation in sound production in the anemonefish Amphiprion akallopisos
Parmentier, Eric ULg; Lagardere, J. P.; Vandewalle, Pierre ULg et al

in Proceedings of the Royal Society B-Biological Sciences (2005), 272(1573), 1697-1703

Because of pelagic-larval dispersal, coral-reef fishes are distributed widely with minimal genetic differentiation between populations. Amphiprion akallopisos, a clownfish that uses sound production to ... [more ▼]

Because of pelagic-larval dispersal, coral-reef fishes are distributed widely with minimal genetic differentiation between populations. Amphiprion akallopisos, a clownfish that uses sound production to defend its anemone territory, has a wide but disjunct distribution in the Indian Ocean. We compared sounds produced by these fishes from populations in Madagascar and Indonesia, a distance of 6500 km. Differentiation of agonistic calls into distinct types indicates a complexity not previously recorded in fishes' acoustic communication. Moreover, various acoustic parameters, including peak frequency, pulse duration, number of peaks per pulse, differed between the two populations. The geographic comparison is the first to demonstrate 'dialects' in a marine fish species, and these differences in sound parameters suggest genetic divergence between these two populations. These results highlight the possible approach for investigating the role of sounds in fish behaviour in reproductive divergence and speciation. [less ▲]

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See detailRecent developments in the field of arrow and dart poisons
Philippe, Geneviève ULg; Angenot, Luc ULg

in Journal of Ethnopharmacology (2005), 100(1-2), 85-91

Arrow and dart poisons, considered as conventional natural sources for future drug discovery, have already provided numerous biologically active molecules used as drugs in therapeutic applications or in ... [more ▼]

Arrow and dart poisons, considered as conventional natural sources for future drug discovery, have already provided numerous biologically active molecules used as drugs in therapeutic applications or in pharmacological research. Plants containing alkaloids or cardiotonic glycosides have generally been the main ingredients responsible for the efficacy of these poisons, although some animals, such as frogs, have also been employed. This paper, without being exhaustive, reports the greater strides made during the past 15 years in the understanding of the chemical nature and biological properties of arrow and dart poison constituents. Examples both of promising biological properties shown by these molecules and of crucial discoveries achieved by their use as pharmacological tools are given. Further studies of these toxic principles are likely to enable scientists to find new valuable lead compounds, useful in many fields of research, like oncology, inflammation and infectious diseases. 2005 Elsevier Ireland Ltd. All rights reserved. [less ▲]

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See detailImpregnation method for detecting annual laminations in sediment cores: An overview
Boes, Xavier; Fagel, Nathalie ULg

in Sedimentary Geology (2005), 179(3-4), 185-194

Annually laminated sediments can provide an absolute time scale (by varve counting) and a high-resolution palaeoclimate information (from varve thickness). Both types of information may be directly ... [more ▼]

Annually laminated sediments can provide an absolute time scale (by varve counting) and a high-resolution palaeoclimate information (from varve thickness). Both types of information may be directly measured from sediment core surfaces. In this paper, we stress that varve counting and varve thickness measurements derived from fresh core surfaces could not systematically reveal the internal sedimentary structure, even if assisted by high resolution image analysis. We present an example of a homogeneous sediment core for which the varves were only observable after core impregnation and polishing steps. Because the impregnation methods are not yet standardized, the aim of this paper is to give an updated review of the methodology. In this review, we present the major critical points during impregnation steps. In particular, we focus on all of the post-treatment sediment disturbances that can alter the laminated micro-structure and, consequently, varve measurements. Finally, we propose a modified impregnation protocol, especially adapted for tracking varved intervals in long cores. (c) 2005 Elsevier B.V. All rights reserved. [less ▲]

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See detailBulletin agrométéorologique - Juillet 2005
Tychon, Bernard ULg; Ozer, Pierre ULg; De Longueville, Florence ULg et al

in Bulletin Agrométéorologique (2005), 4(4), 1-5

Le mois de juillet fut anormalement pluvieux en diverses régions du pays. Les autres paramètres climatiques furent néanmoins proches de la moyenne. Les prévisions de rendements des principales cultures ... [more ▼]

Le mois de juillet fut anormalement pluvieux en diverses régions du pays. Les autres paramètres climatiques furent néanmoins proches de la moyenne. Les prévisions de rendements des principales cultures sont globalement à la baisse sur le territoire par rapport à l’année dernière. [less ▲]

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See detailProanthocyanidins, from Ribes Nigrum Leaves, Reduce Endothelial Adhesion Molecules Icam-1 and Vcam-1
Garbacki, Nancy ULg; Kinet, Marie; Nusgens, Betty ULg et al

in Journal of Inflammation (London, England) (2005), 2

BACKGROUND: The effects of proanthocyanidins (PACs), isolated from blackcurrant (Ribes nigrum L.) leaves, on neutrophil accumulation during inflammatory processes were investigated in vivo and in vitro ... [more ▼]

BACKGROUND: The effects of proanthocyanidins (PACs), isolated from blackcurrant (Ribes nigrum L.) leaves, on neutrophil accumulation during inflammatory processes were investigated in vivo and in vitro. METHODS: In vivo studies were performed using carrageenin-induced pleurisy in rats pre-treated with PACs. Exudate volume and PMNs accumulation were measured. Leukocyte cell adhesion molecules (LFA-1, Mac-1 and VLA-4) mobilization in circulating granulocytes were analysed by flow cytometry and endothelial cell adhesion molecules (ICAM-1 and VCAM-1) were detected by immunohistochemistry on lung sections. In vitro studies were conducted on endothelial LT2 cells, stimulated with TNF-alpha, to evaluate ICAM-1, IL-8 and VEGF mRNA expression upon PACs treatment. Data sets were examined by one-way analysis of variance (ANOVA) followed by a Scheffe post-hoc test. RESULTS: Pretreatment of the animals with PACs (10, 30 and 60 mg/kg) inhibited dose-dependently carrageenin-induced pleurisy in rats by reducing pleural exudate formation and PMNs infliltration. Leukocyte cell adhesion molecules mobilization was not down-regulated on granulocytes by PACs. Immunohistochemistry on lung sections showed a decreased production of endothelial cell adhesion molecules. In vitro experiments demonstrated that PACs were able to significantly inhibit ICAM-1 but not IL-8 and VEGF165 mRNA expression. Moreover, VEGF121 mRNA expression was dose-dependently enhanced. CONCLUSION: This study provides evidence to support the anti-inflammatory activity of proanthocyanidins is related to an inhibition of leukocyte infiltration which can be explained at least in part by a down-regulation of endothelial adhesion molecules, ICAM-1 and VCAM-1 and that these compounds are capable of modulating TNF-alpha-induced VEGF transcription. [less ▲]

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See detailDramatic broadening of the substrate profile of the Aeromonas hydrophila CphA metallo-beta-lactamase by site-directed mutagenesis
Bebrone, Carine ULg; Anne, C.; De Vriendt, K. et al

in Journal of Biological Chemistry (2005), 280(31), 28195-28202

Among class B beta-lactamases, the subclass B2 CphA enzyme is characterized by a unique specificity profile. CphA efficiently hydrolyzes only carbapenems. In this work, we generated site-directed mutants ... [more ▼]

Among class B beta-lactamases, the subclass B2 CphA enzyme is characterized by a unique specificity profile. CphA efficiently hydrolyzes only carbapenems. In this work, we generated site-directed mutants that possess a strongly broadened activity spectrum when compared with the WT CphA. Strikingly, the N116H/N220G double mutant exhibits a substrate profile close to that observed for the broad spectrum subclass B1 enzymes. The double mutant is significantly activated by the binding of a second zinc ion under conditions where the WT enzyme is non-competitively inhibited by the same ion. [less ▲]

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See detailIconographie de l'aura: du magique au sacré
Dondero, Maria Giulia ULg

in Espressione/Contenuto : Rivista dell’Associazione Italiana di Studi Semiotici (2005)

Cet article examine et critique les notions d’« aura » et de reproductibilité technique de W. Benjamin par rapport au medium photographique. En premier lieu l’aura est analysée par rapport à la photo en ... [more ▼]

Cet article examine et critique les notions d’« aura » et de reproductibilité technique de W. Benjamin par rapport au medium photographique. En premier lieu l’aura est analysée par rapport à la photo en tant qu’objet « original » et en même temps reproductible, donc par rapport à son statut hybride qui la situe entre les arts autographiques (syntaxiquement denses selon N. Goodman) et les arts allographiques (arts de la notation et de la reproduction). La photo se présente donc comme un art autographique à objet multiple. En deuxième lieu, l’aura est analysée par rapport à la photo en tant que texte : dans ce cas j’ai étudié l’iconographie de l’aura, c’est-à-dire le halo de lumière dans la photographie spirite du début du XX siècle et dans la photographie contemporaine. Dans le premier cas, le halo est lié à la représentation de la transcendance et à des « syntaxes des présences » qui relèvent d’un circuit magique ; dans le deuxième cas, le halo est lié à une relation entre le visible et l’invisible qui relève des valeurs sacrées de l’existence. La notion d’aura concerne la photo en tant qu’objet ainsi que la photo en tant que texte : dans les deux cas elle concerne une « intersection de présences ». Dans le cas de la photo en tant qu’objet unique, l’intersection de présences concerne la rencontre entre la trace du corps du photographe et le regard actuel de l’observateur qui constitue l’aura ; dans le cas de la photo en tant que texte, c’est la représentation de l’intersection entre visible et invisible (le halo). [less ▲]

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See detailInnovative designs for the imaging suite on Solar Orbiter
Auchere, Frederic; Song, Xueyen; Rouesnel, Frederic et al

in Society of Photo-Optical Instrumentation Engineers (SPIE) Conference Series (2005, August 01)

Orbiting around the Sun on an inclined orbit with a 0.2 UA perihelion, the Solar Orbiter probe will provide high resolution views of the Sun from various angles unattainable from Earth. Together with a ... [more ▼]

Orbiting around the Sun on an inclined orbit with a 0.2 UA perihelion, the Solar Orbiter probe will provide high resolution views of the Sun from various angles unattainable from Earth. Together with a set of high resolution imagers, the Full Sun Imager is part of the EUV Imaging suite of the Solar Orbiter mission. The mission's ambitious characteristics draw severe constraints on the design of these instruments. We present a photometrically efficient, compact, and lightweight design for the Full Sun Imager. With a 5 degrees field of view, this telescope will be able to see the global solar coronal structure from high viewing angles. Thermal solutions reducing the maximum power trapped in the High Resolution Imagers are also proposed. [less ▲]

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See detailColloidal stability of aqueous suspensions of barium zirconate
Boschini, Frédéric ULg; Rulmont, André ULg; Cloots, Rudi ULg et al

in Journal of the European Ceramic Society (2005), 25(13), 3195-3201

In this article, the colloidal behaviour of aqueous suspensions of barium zirconate is investigated. The variation of zeta-potential as a consequence of changing the pH and the concentration of an anionic ... [more ▼]

In this article, the colloidal behaviour of aqueous suspensions of barium zirconate is investigated. The variation of zeta-potential as a consequence of changing the pH and the concentration of an anionic polyelectrolyte is studied, the isoelectric point occurring at pH 5.3. The IEP shifts down on calcining the powder and also when anionic polyelectrolytes are added. Rheological studies have been made on suspensions prepared to a solids loading of 27 vol.% (72 wt.%). Optimum dispersing conditions are reached for suspensions prepared at basic pH with 1.5 wt.% tetramethylammonium hydroxide (TMAH) and a concentration of ammonium polymethacrylate (PMAA) of 1.6 wt.%. Comparison with similar suspensions prepared with NaOH instead PMAA demonstrated that TMAH gives an extra contribution to stability, probably related to the adsorption of N+(Me)(4) groups. The suspensions were slip cast, and green densities higher than 60% of theoretical were obtained. (c) 2004 Elsevier Ltd. All rights reserved. [less ▲]

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See detailLiver transplantation in Jehovah's witnesses
Detry, Olivier ULg; De Roover, Arnaud ULg; Delwaide, Jean ULg et al

in Transplant International (2005), 18(8), 929-936

For religious reasons, Jehovah's witnesses refuse transfusion of blood products (red cells, platelets, plasma), but may accept organ transplantation. The authors developed a multidisciplinary protocol for ... [more ▼]

For religious reasons, Jehovah's witnesses refuse transfusion of blood products (red cells, platelets, plasma), but may accept organ transplantation. The authors developed a multidisciplinary protocol for liver transplantation in Jehovah's witnesses. In a 6-year period, nine Jehovah's witness patients were listed for liver transplantation. They received preoperative erythropoietin therapy, with iron and folic acid that allowed significant haematocrit increase. Two patients underwent partial spleen embolization to increase platelet count. Seven patients underwent cadaveric whole liver transplantation, and two right lobe living-related liver transplantation, using continuous circuit cell saving system and high dose aprotinin. No patient received any blood product during the surgical procedure. One patient suffering from deep anaemia after living-related liver transplantation was transfused as required by his family, but died from aspergillus infection. One 6-year-old child was transfused against her parent's will. The authors demonstrated that it is possible to increase haematocrit and platelet levels in cirrhotic patients awaiting liver transplantation. They were able to reduce intraoperative need for blood products, allowing liver transplantation in prepared Jehovah's witness patients. This experience may be beneficial for non-Jehovah's witness liver transplant recipients. [less ▲]

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See detailLe rôle des ressources humaines face au changement culturel
Robert, Jocelyne ULg

Article for general public (2005)

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