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Freeman Stephen

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Main Referenced Co-authors
Malgrange, Brigitte  (11)
Delacroix, Laurence  (9)
Mateo Sanchez, Susana  (9)
Nguyen, Laurent  (8)
Chariot, Alain  (5)
Main Referenced Keywords
development (5); inner ear (5); Elongator (4); apoptosis (1); Article (1);
Main Referenced Unit & Research Centers
Giga Neurosciences - ULiège [BE] (5)
Main Referenced Disciplines
Otolaryngology (7)
Anatomy (cytology, histology, embryology...) & physiology (7)
Biochemistry, biophysics & molecular biology (6)
Genetics & genetic processes (6)
Oncology (2)

Publications (total 20)

The most downloaded
109 downloads
Dedobbeleer, M., Willems, E., Lambert, J., LOMBARD, A., Di Gregorio, M., Lumapat, P. N., Di Valentin, E., Freeman, S., Goffart, N., Scholtes, F., & Rogister, B. (2020). MKP1 phosphatase is recruited by CXCL12 in glioblastoma cells and plays a role in DNA strand breaks repair. Carcinogenesis. doi:10.1093/carcin/bgz151 https://hdl.handle.net/2268/248005

The most cited

184 citations (Scopus®)

Wang, S., Ai, X., Freeman, S., Pownall, M., Lu, Q., Kessler, D., & Emerson Jr, C. (2004). QSulf1, a heparan sulfate 6-O-endosulfatase, inhibits fibroblast growth factor signaling in mesoderm induction and angiogensis. Proceedings of the National Academy of Sciences of the United States of America. doi:10.1073/pnas.0401028101 https://hdl.handle.net/2268/258759

Moortgat, S., Manfroid, I., Pendeville-Samain, H., Freeman, S., Bourdouxhe, J., Benoit, V., Merhi, A., Philippe, C., Faivre, L., & Maystadt, I. (2021). Broadening the phenotypic spectrum and physiological insights related to EIF2S3 variants. Human Mutation, 42 (7), 827-834. doi:10.1002/humu.24215
Peer Reviewed verified by ORBi

Dedobbeleer, M., Willems, E., Lambert, J., LOMBARD, A., Di Gregorio, M., Lumapat, P. N., Di Valentin, E., Freeman, S., Goffart, N., Scholtes, F., & Rogister, B. (2020). MKP1 phosphatase is recruited by CXCL12 in glioblastoma cells and plays a role in DNA strand breaks repair. Carcinogenesis. doi:10.1093/carcin/bgz151
Peer Reviewed verified by ORBi

Freeman, S.* , Mateo Sánchez, S.* , Pouyo, R., Van Lerberghe, P.-B., Hanon, K., Thelen, N., Thiry, M., Morelli, G., Van Hees, L., Laguesse, S., Chariot, A., Nguyen, L., Delacroix, L.* , & Malgrange, B.*. (2019). Proteostasis is essential during cochlear development for neuron survival and hair cell polarity. EMBO Reports, 20 (9). doi:10.15252/embr.201847097
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Even, A., Morelli, G., Broix, L., Scaramuzzino, C., Turchetto, S., Gladwyn-Ng, I., Le Bail, R., Shilian, M., Freeman, S., Magiera, M. M., Jijumon, A. S., Krusy, N., Malgrange, B., Brone, B., Dietrich, P., Dragatsis, I., Janke, C., Saudou, F., Weil, M., & Nguyen, L. (2019). ATAT1-enriched vesicles promote microtubule acetylation via axonal transport. Science Advances, 5 (12), 2705. doi:10.1126/sciadv.aax2705
Peer Reviewed verified by ORBi

LOMBARD, A., Dedobbeleer, M., DEWANDRE, Q., REUTER, G., Freeman, S., Di Valentin, E., MARTIN, D., & ROGISTER, B. (November 2018). Deciphering the response of subventricular zone-nested glioblastoma cells after surgery [Poster presentation]. Society for NeuroOncology (SNO), New Orleans, United States - Louisiana.

Delacroix, L., Freeman, S., Mateo Sánchez, S., Pouyo, R., Czajkowski, A., Nguyen, L., & Malgrange, B. (15 November 2017). Elp3 controls early cochlear development [Paper presentation]. Annual Meeting 2017 - Society for Neuroscience, Washington DC, United States.

Dedobbeleer, M., Willems, E., Freeman, S., Goffart, N., LOMBARD, A., & Rogister, B. (11 August 2017). Phosphatases and solid tumors: focus on glioblastoma initiation, progression and recurrences. Biochemical Journal, 474 (17), 2903-2924. doi:10.1042/BCJ20170112
Peer Reviewed verified by ORBi

Freeman, S., Mateo Sanchez, S., Delacroix, L., & Malgrange, B. (18 May 2016). Disruption of the lysine acetyltransferase Elp3 causes planar polarity defects in the mouse organ of Corti [Poster presentation]. 10th Molecular Biology of Hearing and Deafness Conference.

Delacroix, L., Mateo Sanchez, S., Freeman, S., Nguyen, L., & Malgrange, B. (20 February 2016). Elp3 Lysine Acetyl-Transferase Controls Neuronal Survival in the Developing Inner Ear and is Crucial to Balance and Hearing [Paper presentation]. Association for Research in Otolaryngology, 39th Midwinter Meeting, San Diego, United States.

Mateo Sanchez, S., Delacroix, L., Freeman, S., Laguesse, S., Huysseune, S., Delrez, S., Chariot, A., Nguyen, L., & Malgrange, B. (25 January 2016). Unravelling the roles of lysine acetylation by Elp3 during inner ear development [Poster presentation]. GIGA-Day.

Renauld, J., Freeman, S., Thelen, N., Johnen, N., Malgrange, B., & Thiry, M. (2016). Changes in the structure and the composition of microtubules within supporting cells of the organ of hearing during development [Poster presentation]. EMBO/EMBL Symposia Microtubules: From Atoms to Complex Systems, Heidelberg, Germany.

Mateo Sanchez, S., Freeman, S., Delacroix, L., & Malgrange, B. (2016). The Role of Post-Translational Modifications in Hearing and Deafness. Cellular and Molecular Life Sciences. doi:10.1007/s00018-016-2257-3
Peer Reviewed verified by ORBi

Mateo Sanchez, S., Delacroix, L., Freeman, S., Laguesse, S., Huysseune, S., Delrez, S., Chariot, A., Nguyen, L., & Malgrange, B. (23 November 2015). UNRAVELLING THE ROLES OF LYSINE ACETYLATION BY ELP3 DURING INNER EAR DEVELOPMENT [Poster presentation]. Belgian Society for Cell and Developmental Biology (BSCDB).

Mateo Sanchez, S., Delacroix, L., Freeman, S., Laguesse, S., Huysseune, S., Delrez, S., Chariot, A., Nguyen, L., & Malgrange, B. (06 June 2015). UNRAVELLING THE ROLES OF LYSINE ACETYLATION BY ELP3 DURING INNER EAR DEVELOPMENT [Poster presentation]. Belgian Society for Cell and Developmental Biology (BSCDB).

Mateo Sanchez, S., Delacroix, L., Freeman, S., Laguesse, S., Huysseune, S., Chariot, A., Nguyen, L., & Malgrange, B. (27 January 2015). Unravelling the roles of lysine acetylation by Elp3 during inner ear development [Poster presentation]. GIGA-Day.

Freeman, S., Keino-Masu, K., Masu, M., & Ladher, R. (2015). Expression of the heparan sulfate 6-O-endosulfatases, Sulf1 and Sulf2, in the avian and mammalian inner ear suggests a role for sulfation during inner ear development. Developmental Dynamics. doi:10.1002/DVDY.24223
Peer Reviewed verified by ORBi

Mulvaney, J., Amemiya, Y., Freeman, S., Ladher, R., & Dabdoub, A. (2014). Molecular cloning and characterisation of chicken Atonal homologue 1: a comparison with human Atoh1. Biology of the Cell, 107 (2), 41-60. doi:10.1111/boc.201400078
Peer Reviewed verified by ORBi

Freeman, S., & Daudet, N. (2012). Artificial inducion of Sox21 regulates sensory cell formation in the embryonic chicken inner ear. PLoS ONE. doi:10.1371/journal.pone.0046387
Peer Reviewed verified by ORBi

Freeman, S., Moore, W., Guiral, E., Holme, A., Turnbull, J., & Pownall, M. (2008). Extracellular regulation of developmental cell signalling by XtSulf1. Developmental Biology, 320 (2), 436-445. doi:10.1016/j.ydbio.2008.05.554
Peer Reviewed verified by ORBi

Wang, S., Ai, X., Freeman, S., Pownall, M., Lu, Q., Kessler, D., & Emerson Jr, C. (2004). QSulf1, a heparan sulfate 6-O-endosulfatase, inhibits fibroblast growth factor signaling in mesoderm induction and angiogensis. Proceedings of the National Academy of Sciences of the United States of America. doi:10.1073/pnas.0401028101
Peer Reviewed verified by ORBi

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