Profil

Molina Ortiz Patricia

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Main Referenced Co-authors
Cano, Amparo (7)
Portillo, Francisco (7)
Schurmans, Stéphane  (6)
MacPherson, Matthew (4)
Santos, Vanesa (3)
Main Referenced Keywords
EMT (2); GTPase activating protein (2); Megakaryocyte (2); Rasa3 (2); adaptor proteins (1);
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (17)

Publications (total 17)

The most downloaded
537 downloads
Scoumanne, A., Molina Ortiz, P., Monteyne, D., Perez-Morga, D., Erneux, C., & Schurmans, S. (2016). Specific expression and function of inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) in wild type and knock-out mice. Advances in Biological Regulation, 62, 1-10. doi:10.1016/j.jbior.2016.03.001 https://hdl.handle.net/2268/194708

The most cited

182 citations (Scopus®)

Moreno-Bueno, G.* , Peinado, H.* , Molina Ortiz, P.* , Olmeda, D., Cubillo, E., Santos, V., Palacios, J., Portillo, F., & Cano, A. (15 October 2009). The morphological and molecular features of the epithelial-to-mesenchymal transition. Nature Protocols, 4, 1591-1613. doi:10.1038/nprot.2009.152 https://hdl.handle.net/2268/183137

Moes, B., Li, H., Molina Ortiz, P., Radermecker, C., Rosu, A., Vande Catsyne, C.-A., Sayyed, S. A., Fontela Joao, Duque, M., Mostafa, A., Azzi, A., Barata Joao T., Merino Ramon, Xu, C., Desmet, C., & Schurmans, S. (2023). INPP5K controls the dynamic structure and signaling of wild type and mutated, leukemia-associated IL7 receptors. Blood, 141, 1708-1717. doi:10.1182/blood.2022017819
Peer Reviewed verified by ORBi

Vande Catsyne, C.-A., Sayyed, S. A., Molina Ortiz, P., Moës, B., Communi, D., Muller, J., Heusschen, R., CAERS, J., Azzi, A., Erneux, C., & Schurmans, S. (2020). Altered chondrocyte differentiation, matrix mineralization and MEK-Erk1/2 signaling in an INPPL1 catalytic knock-out mouse model of opsismodysplasia. Advances in Biological Regulation, 76, 100651. doi:10.1016/j.jbior.2019.100651
Peer Reviewed verified by ORBi

Molina Ortiz, P.* , Orban, T.* , Martin, M., Habets, A., Dequiedt, F.* , & Schurmans, S.*. (2018). Rasa3 controls turnover of endothelial cell adhesion and vascular lumen integrity by a Rap1-dependent mechanism. PLoS Genetics. doi:10.1371/journal.pgen.1007195
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Scoumanne, A., Molina Ortiz, P., Monteyne, D., Perez-Morga, D., Erneux, C., & Schurmans, S. (2016). Specific expression and function of inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) in wild type and knock-out mice. Advances in Biological Regulation, 62, 1-10. doi:10.1016/j.jbior.2016.03.001
Peer Reviewed verified by ORBi

Villarejo, A., Molina Ortiz, P., Montenegro, Y., Moreno-Bueno, G., Morales, S., Santos, V., Gridley, T., Perez-Moreno, M., Peinado, H., Portillo, F., Cales, C., & Cano, A. (16 March 2015). Loss of Snail2 favors skin tumor progression by promoting the recruitment of myeloid progenitors. Carcinogenesis, 36 (5), 585-597. doi:10.1093/carcin/bgv021
Peer Reviewed verified by ORBi

Schurmans, S., Polizzi, S., Scoumanne, A., Sayyed, S. A., & Molina Ortiz, P. (2015). The Ras/Rap GTPase activating protein RASA3 : from gene structure to in vivo functions. Advances in Biological Regulation, 57, 153-161. doi:10.1016/j.jbior.2014.09.006
Peer Reviewed verified by ORBi

Molina Ortiz, P. (October 2014). Rasa3 catalytic activity controls Rap1 activation and integrin signaling during megakaryocyte differentiation in mouse [Poster presentation]. 39th Symposium on Hormones and Cell Regulation.

Villarejo, Cortés-Cabrera, A., Molina Ortiz, P., Portillo, F., & Cano, A. (10 January 2014). Differential role of snail1 and snail2 zinc fingers in E-cadherin repression and epithelial to mesenchymal transition. Journal of Biological Chemistry, 289 (2), 930-941. doi:10.1074/jbc.M113.528026
Peer Reviewed verified by ORBi

Molina Ortiz, P., Polizzi, S., Ramery, E., Gayral, S., Delierneux, C., Oury, C., Iwashita, S., & Schurmans, S. (2014). Rasa3 Controls Megakaryocyte Rap1 Activation, Integrin Signaling and Differentiation into Proplatelet. PLoS Genetics, 10 (6), 1004420. doi:10.1371/journal.pgen.1004420
Peer Reviewed verified by ORBi

Molina Ortiz, P., Villarejo, A., MacPherson, M., Santos, V., Montes, A., Souchelnytskyi, S., Portillo, F., & Cano, A. (02 May 2012). Characterization of the SNAG and SLUG Domains of Snail2 in the Repression of E-Cadherin and EMT Induction: Modulation by Serine 4 Phosphorylation. PLoS ONE, 7 (5), 36132. doi:10.1371/journal.pone.0036132
Peer Reviewed verified by ORBi

Molina Ortiz, P. (2010). Caracterización funcional de Snail2 como represor de cadherina- E y como regulador del proceso de carcinogenésis química [Doctoral thesis, Universidad Autonoma de Madrid]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/183152

MacPherson, M.* , Molina Ortiz, P.* , Soucheknytskyi, S., Wernstedt, C., Martin-Perez, J., Portillo, F., & Cano, A. (15 January 2010). Phosphorylation of Serine 11 and Serine 92 as New Positive Regulators of Human Snail1 Function: Potential Involvement of Casein Kinase-2 and the cAMP-activated Kinase Protein Kinase A. Molecular Biology of the Cell, 21 (2), 244-253. doi:10.1091/mbc.E09-06-0504
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Moreno-Bueno, G.* , Peinado, H.* , Molina Ortiz, P.* , Olmeda, D., Cubillo, E., Santos, V., Palacios, J., Portillo, F., & Cano, A. (15 October 2009). The morphological and molecular features of the epithelial-to-mesenchymal transition. Nature Protocols, 4, 1591-1613. doi:10.1038/nprot.2009.152
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Molina Ortiz, P., MacPherson, M., Cano, A., & Portillo, F. (02 December 2007). Functional Characterization of Snail2 Mediated E-Cadherin repression [Poster presentation]. International Workshop on Cancer Stem Cells, Milan, Italy.

Molina Ortiz, P., MacPherson, M., Cano, A., & Portillo, F. (10 September 2007). Functional Characterization of Snail2 repression complex [Poster presentation]. 3er EMT meeting.

Hongbing, L., Sánchez-Torres, J., del Carpio, A. F., Nogales-González, A., Molina Ortiz, P., Moreno, M. J., Török, K., & Villalobo, A. (16 June 2005). The adaptor Grb7 is a novel calmodulin-binding protein: functional implications of the interaction of calmodulin with Grb7. Oncogene, 24 (26), 4206-4219. doi:10.1038/sj.onc.1208591
Peer Reviewed verified by ORBi

Villalobo, A., Garcia-Andres, C., & Molina Ortiz, P. (April 2003). Translocation of ErbB receptors into the nucleus. Clinical and Translational Oncology, 5 (7), 381-389.
Peer Reviewed verified by ORBi

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