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Göktuna Serkan

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Main Referenced Co-authors
Chariot, Alain  (7)
Shostak, Kateryna  (6)
Close, Pierre  (5)
Klevernic, Iva  (3)
Ladang, Aurélie  (3)
Main Referenced Keywords
AKT (1); Animal Science and Zoology (1); Cancer cells (1); Dclk1 (1); Drug Discovery (1);
Main Referenced Unit & Research Centers
Giga-Signal Transduction - ULiège [BE] (4)
Main Referenced Disciplines
Oncology (4)
Biochemistry, biophysics & molecular biology (3)
Hematology (1)
Anatomy (cytology, histology, embryology...) & physiology (1)

Publications (total 8)

The most downloaded
219 downloads
Stellzig, J., Chariot, A., Shostak, K., Göktuna, S., Renner, F., Acker, T., Pagenstecher, A., & Schmitz, M. (11 November 2013). Deregulated expression of TANK in glioblastomas triggers pro-tumorigenic ERK1/2 and AKT signaling pathways. Observatoire (L'), e79. doi:10.1038/oncsis.2013.42 https://hdl.handle.net/2268/161182

The most cited

97 citations (Scopus®)

Shostak, K., Zhang, X., Hubert, P., Göktuna, S., Jiang, Z., Klevernic, I., Hildebrand, J., Roncarati, P., Hennuy, B., Ladang, A., SOMJA, J., Gothot, A., Close, P., Delvenne, P., & Chariot, A. (2014). NF-kappaB-induced KIAA1199 promotes survival through EGFR signalling. Nature Communications, 5, 5232. doi:10.1038/ncomms6232 https://hdl.handle.net/2268/174135

Göktuna, S. (03 January 2022). IKBKE-DRIVEN TPL2 AND MEK1 PHOSPHORYLATIONS SUSTAIN CONSTITUTIVE ERK1/2 ACTIVATION IN TUMOR CELLS. EXCLI Journal, 21, 436 - 453. doi:10.17179/excli2021-4578
Peer Reviewed verified by ORBi

Göktuna, S., Shostak, K., Chau, T.-L., Heukamp, L., Hennuy, B., Duong, H. Q., LADANG, A., Close, P., Klevernic, I., Olivier, F., Florin, A., Ehx, G., Baron, F., Vandereyken, M., Rahmouni, S., Vereecke, L., van Loo, G., Büttner, R., Greten, F., & Chariot, A. (2016). The Prosurvival IKK-Related Kinase IKK« Integrates LPS and IL17A Signaling Cascades to Promote Wnt-Dependent Tumor Development in the Intestine. Cancer Research, 76, 2587-99. doi:10.1158/0008-5472.CAN-15-1473
Peer Reviewed verified by ORBi

LADANG, A.* , Rapino, F.* , Heukamp, L., Tharun, L., Shostak, K., Hermand, D., Delaunay, S., Klevernic, I., Jiang, Z., Jacques, N., Jamart, D., Migeot, V., Florin, A., Göktuna, S., Malgrange, B., Samson, O., Nguyen, L., Buettner, R., Close, P., & Chariot, A. (16 November 2015). Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine. Journal of Experimental Medicine, 212 (12), 2057-75. doi:10.1084/jem.20142288
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Chau, T.-L., Göktuna, S., Rammal, A., Casanova Bustos, T. R., Duong, H. Q., GATOT, J.-S., Close, P., Dejardin, E., Desmecht, D., Shostak, K., & Chariot, A. (2015). A role for APPL1 in tlr3/4-dependent TBK1 and IKKε activation in macrophages. Journal of Immunology. doi:10.4049/jimmunol.1401614
Peer Reviewed verified by ORBi

Shostak, K.* , Patrascu, F.* , Göktuna, S., Close, P., Borgs, L., Nguyen, L., Olivier, F., Rammal, A., Brinkhaus, H., Bentires-Alj, M., Marine, J.-C., & Chariot, A. (May 2014). MDM2 restrains estrogen-mediated AKT activation by promoting TBK1-dependent HPIP degradation. Cell Death and Differentiation, 5 (21), 811-24. doi:10.1038/cdd.2014.2
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Shostak, K., Zhang, X., Hubert, P., Göktuna, S., Jiang, Z., Klevernic, I., Hildebrand, J., Roncarati, P., Hennuy, B., Ladang, A., SOMJA, J., Gothot, A., Close, P., Delvenne, P., & Chariot, A. (2014). NF-kappaB-induced KIAA1199 promotes survival through EGFR signalling. Nature Communications, 5, 5232. doi:10.1038/ncomms6232
Peer Reviewed verified by ORBi

Göktuna, S., Canli, O., Bollrath, J., Fingerle, A. A., Horst, D., Diamanti, M. A., Pallangyo, C., Bennecke, M., Nebelsiek, T., Mankan, A. K., Lang, R., Artis, D., Hu, Y., Patzelt, T., Ruland, J., Kirchner, T., Taketo, M. M., Chariot, A., Arkan, M. C., & Greten, F. R. (2014). IKKalpha promotes intestinal tumorigenesis by limiting recruitment of M1-like polarized myeloid cells. Cell Reports, 7 (6), 1914-25. doi:10.1016/j.celrep.2014.05.006
Peer Reviewed verified by ORBi

Stellzig, J., Chariot, A., Shostak, K., Göktuna, S., Renner, F., Acker, T., Pagenstecher, A., & Schmitz, M. (11 November 2013). Deregulated expression of TANK in glioblastomas triggers pro-tumorigenic ERK1/2 and AKT signaling pathways. Observatoire (L'), e79. doi:10.1038/oncsis.2013.42
Peer reviewed

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