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Mantanus Jérôme

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Main Referenced Co-authors
Hubert, Philippe  (41)
Ziemons, Eric  (41)
Rozet, Eric  (25)
Evrard, Brigitte  (24)
Lebrun, Pierre  (23)
Main Referenced Keywords
Validation (10); Near infrared spectroscopy (9); Process Analytical Technology (9); Near infrared (8); Spectroscopie proche infrarouge (6);
Main Referenced Unit & Research Centers
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège [BE] (17)
C.I.R.M. (12)
C.I.R.M (1)
CRIM (1)
Centre Interfacultaire de Recherche du Médicament (1)
Main Referenced Disciplines
Pharmacy, pharmacology & toxicology (43)

Publications (total 43)

The most downloaded
724 downloads
Mantanus, J., Ziemons, E., Lebrun, P., Rozet, E., Klinkenberg, R., Streel, B., & Hubert, P. (2008). Moisture content determination of pharmaceutical pellets by near infrared spectroscopy: model selection, evaluation and validation [Poster presentation]. 11th Conference on Chemometrics in Analytical Chemistry, Montpellier, France. https://hdl.handle.net/2268/38610

The most cited

140 citations (Scopus®)

Lebrun, P., Krier, F., Mantanus, J., Grohganz, H., Yang, M., Rozet, E., Boulanger, B., Evrard, B., Rantanen, J., & Hubert, P. (2012). Design space approach in the optimization of the spray-drying process. European Journal of Pharmaceutics and Biopharmaceutics, 80 (1), 226-234. doi:10.1016/j.ejpb.2011.09.014 https://hdl.handle.net/2268/100593

Ziemons, E., Mantanus, J., Rozet, E., Lebrun, P., Klinkerberg, R., Streel, B., Evrard, B., & Hubert, P. (March 2012). AN INNOVATIVE APPROACH TO SELECT THE PREDICTION MODEL IN THE DEVELOPMENT OF NIR SPECTROSCOPIC METHODS [Poster presentation]. AGROSTAT 2012, Paris, France.

De Bleye, C., Chavez, P.-F., Mantanus, J., Marini Djang'Eing'A, R., Hubert, P., Rozet, E., & Ziemons, E. (2012). Critical Review of Near-Infrared Spectroscopic Methods Validations in Pharmaceutical Applications. Journal of Pharmaceutical and Biomedical Analysis, 69, 125-132. doi:10.1016/j.jpba.2012.02.003
Peer Reviewed verified by ORBi

Lebrun, P., Krier, F., Mantanus, J., Grohganz, H., Yang, M., Rozet, E., Boulanger, B., Evrard, B., Rantanen, J., & Hubert, P. (2012). Design space approach in the optimization of the spray-drying process. European Journal of Pharmaceutics and Biopharmaceutics, 80 (1), 226-234. doi:10.1016/j.ejpb.2011.09.014
Peer Reviewed verified by ORBi

Krier, F., Mantanus, J., Ziemons, E., & Evrard, B. (October 2011). In-line active content determination of polymeric implant by near infrared spectroscopy [Poster presentation]. AAPS Annual Meeting and Exposition, Washington, United States.

Mantanus, J., Rozet, E., Van Butsele, K., De Bleye, C., Ceccato, A., Evrard, B., Hubert, P., & Ziemons, E. (October 2011). Silicone-based drug reservoirs manufacturing process - Critical quality attributes evaluation using NIR and Raman spectroscopy [Poster presentation]. AAPS Annual Meeting and Exposition, Washington, United States.

Mantanus, J. (2011). New pharmaceutical applications involving Near Infrared spectroscopy as a PAT compliant process analyzer [Doctoral thesis, Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/314910

Marini Djang'Eing'A, R., Mbinze Kindenge, J., Debrus, B., Lebrun, P., Mantanus, J., Ziemons, E., Lamalle, C., Fillet, M., Rudaz, S., & Hubert, P. (September 2011). IMPLEMENTATION OF GENERIC ANALYTICAL METHODS TO FIGHT AGAINST COUNTERFEIT MEDICINES [Paper presentation]. Recent Development in Pharmaceutical Analysis (RDPA), Pavia, Italy.

De Bleye, C., Mantanus, J., Rozet, E., Van Butsele, K., Marini Djang'Eing'A, R., Ceccato, A., Evrard, B., Hubert, P., & Ziemons, E. (September 2011). BUILDING THE QUALITY INTO THE POLYMERIC SOLID DOSAGE FORM MANUFACTURING LINE - CRITICAL QUALITY ATTRIBUTES EVALUATION WITH NIR AND RAMAN PAT TOOLS [Poster presentation]. Recent Development in Pharmaceutical Analysis (RDPA), Pavia, Italy.

Ziemons, E., Mantanus, J., Rozet, E., Lebrun, P., Krier, F., Evrard, B., & Hubert, P. (June 2011). La spectroscopie vibrationnelle, outil indispensable pour l'industrie pharmaceutique ?

Mantanus, J., Rozet, E., Lebrun, P., Evrard, B., Hubert, P., & Ziemons, E. (19 May 2011). Une solution analytique verte pour le PAT: la spectroscopie proche infrarouge [Paper presentation]. Chimie analytique verte: chromatographie en phase supercritique, liquides ioniques, haute température et miniaturisation, Paris, France.

Mantanus, J., Rozet, E., Van Butsele, K., De Bleye, C., Ceccato, A., Evrard, B., Hubert, P., & Ziemons, E. (2011). Near infrared and Raman spectroscopy as Process Analytical Technology tools for the manufacturing of silicone-based drug reservoirs. Analytica Chimica Acta, 699, 96-106. doi:10.1016/j.aca.2011.05.006
Peer Reviewed verified by ORBi

Ziemons, E., Bourichi, H., Mantanus, J., Rozet, E., Lebrun, P., Essassi, E., Cherrah, Y., Bouklouze, A., & Hubert, P. (2011). Determination of binary polymorphic mixtures of fluconazole using near infrared spectroscopy and X-ray powder diffraction: A comparative study based on the pre-validation stage results. Journal of Pharmaceutical and Biomedical Analysis, 55, 1208-1212. doi:10.1016/j.jpba.2011.02.019
Peer Reviewed verified by ORBi

Ziemons, E., Mantanus, J., Rozet, E., Lebrun, P., Klinkenberg, R., Streel, B., Moonen, F., Evrard, B., & Hubert, P. (08 December 2010). Vibrational spectroscopy in pharmaceutical industry: From development of the most appropriate predictive model to routine implementation [Poster presentation]. BioWin Day 2010, Louvain-la-Neuve, Belgium.

Ziemons, E., Mantanus, J., Rozet, E., Lebrun, P., Klinkenberg, R., Streel, B., Evrard, B., Moonen, F., & Hubert, P. (02 December 2010). Use of tolerance intervals in the development of near infrared spectroscopic methods: An innovative way to select the most appropriate calibration model [Poster presentation]. Chimiométrie 2010, Paris, France.

Mantanus, J., Ziemons, E., Streel, B., Klinkenberg, R., Evrard, B., Rantanen, J., & Hubert, P. (15 November 2010). NIR monitoring of solid and liquid forms manufacturing – Development and validation of in-line quantitative methods [Poster presentation]. FIP Pharmaceutical Sciences 2010 world congress, New Orleans, United States.

Tiuca, I., Mantanus, J., Iacob, B., Ede, B., Oprean, R., Hubert, P., & Ziemons, E. (November 2010). Raman spectroscopic study of complex formation between major calixarene derivatives and three pharmaceutical substances [Poster presentation]. Jours de l’Université de Médecine et Pharmacie „Iuliu Haţieganu”, Cluj-Napoca, Romania.

Mantanus, J., Lebrun, P., Rozet, E., Evrard, B., Hubert, P., & Ziemons, E. (14 October 2010). La spectroscopie proche infrarouge et Raman: Nouvelles armes vertes dans le contrôle de la qualité du médicament [Poster presentation]. Journée Scientifique Annuelle de la Société Royale de Chimie: Chimie Verte, Gembloux, Belgium.

Hubert, P., Ziemons, E., Mantanus, J., Lebrun, P., Boulanger, B., & Rozet, E. (October 2010). RISK MANAGMENT IN THE VALIDATION OF ANALYTICAL METHODS [Paper presentation]. CNFR 2010 Congress, Targu-Mures, Romania.

Mantanus, J., Ziemons, E., Van Butsele, K., Evrard, B., Ceccato, A., & Hubert, P. (24 September 2010). NIR AND RAMAN SPECTROSCOPY AS PAT TOOLS FOR THE MANUFACTURING OF SILICONE-BASED DRUG RESERVOIRS [Paper presentation]. Drug Analysis 2010, Anvers, Belgium.

Marini Djang'Eing'A, R., Mbinze Kindenge, J., Montes, M. L. A., Debrus, B., Lebrun, P., Mantanus, J., Ziemons, E., Rohrbasser, C., Rudaz, S., & Hubert, P. (September 2010). Analytical tools to fight against counterfeit medicines. Chimica Oggi, 28 (5), 10-14.
Peer Reviewed verified by ORBi

Ziemons, E., Mantanus, J., Rozet, E., Lebrun, P., Klinkenberg, R., Streel, B., Evrard, B., & Hubert, P. (September 2010). An innovative approach to select the prediction model in the development of NIR spectroscopy methods [Poster presentation]. Drug Analysis, Antwerpen, Belgium.

Marini Djang'Eing'A, R., Mbinze Kindenge, J., Montes, M. L. A., Debrus, B., Lebrun, P., Mantanus, J., Ziemons, E., Rudaz, S., & Hubert, P. (September 2010). Contribution to fight against counterfeit medecines applying several analytical tools [Poster presentation]. International Symposium on Drug Analysis 2010, Anvers, Belgium.

Marini Djang'Eing'A, R., Mbinze Kindende, J., Lecomte, F., Debrus, B., Lebrun, P., Rozet, E., Mantanus, J., Ziemons, E., & Hubert, P. (31 July 2010). La contrefaçon des médicaments : outils pour lutter contre ce fléau [Paper presentation]. Conférence Scientifique, Kisangani, Province Orientale, Congo - Kinshasa.

Mantanus, J., Ziemons, E., Evrard, B., Van Butsele, K., Ceccato, A., & Hubert, P. (05 May 2010). NIR Real-time monitoring of a silicone-based drug reservoir crosslinking process [Poster presentation]. 4th Pan European Pat Science conference, Kuopio, Finland.

Mantanus, J., Ziemons, E., Streel, B., Klinkenberg, R., Evrard, B., Rantanen, J., & Hubert, P. (05 May 2010). NIR as a PAT tool for solid and liquid forms manufacturing - Development and validation of in-line quantitative methods [Poster presentation]. 4th Pan European Pat Science conference, Kuopio, Finland.

Mantanus, J., Ziemons, E., Lebrun, P., Rozet, E., Klinkenberg, R., Streel, B., Evrard, B., & Hubert, P. (2010). Active content determination of non-coated pharmaceutical pellets by near infrared spectroscopy: Method development, validation and reliability evaluation. Talanta, 80, 1750-1757. doi:10.1016/j.talanta.2009.10.019
Peer Reviewed verified by ORBi

Mantanus, J., Ziemons, E., Rozet, E., Streel, B., Klinkenberg, R., Evrard, B., Rantanen, J., & Hubert, P. (2010). Building the quality into pellet manufacturing environment - feasibility study and validation of an in-line quantitative near infrared (NIR) method. Talanta, 83, 305-311. doi:10.1016/j.talanta.2010.09.009
Peer Reviewed verified by ORBi

Ziemons, E., Mantanus, J., Lebrun, P., Rozet, E., Evrard, B., & Hubert, P. (2010). Acetaminophen determination in low-dose pharmaceutical syrup by NIR spectroscopy. Journal of Pharmaceutical and Biomedical Analysis, 53, 510-516. doi:10.1016/j.jpba.2010.06.003
Peer Reviewed verified by ORBi

Mantanus, J., Ziemons, E., Lebrun, P., Rozet, E., Klinkenberg, R., Streel, B., & Hubert, P. (November 2009). Active content determination of non-coated pharmaceutical pellets by near infrared spectroscopy: Method development, validation and reliability evaluation [Poster presentation]. Annual Meeting and Exposition of the American Association of Pharmaceutical Scientists, Los Angeles, United States.

Mantanus, J., Ziemons, E., Lebrun, P., Rozet, E., Rudaz, S., Klinkenberg, R., Streel, B., & Hubert, P. (September 2009). Validation of a near infrared spectroscopy method for the quantitative determination of an active ingredient in non-coated pharmaceutical pellets [Poster presentation]. 13th International Meeting of Recent Developments in Pharmaceutical Analysis, Milan, Italy.

Mantanus, J., Ziemons, E., Streel, B., Klinkenberg, R., Evrard, B., Hubert, P., & Rantanen, J. (September 2009). Production line real time near infrared (NIR) monitoring [Paper presentation]. 3rd Annual Pharmaceutical Solid State Research Cluster Symposium, Copenhagen, Denmark.

Mantanus, J., Ziemons, E., Streel, B., Klinkenberg, R., Evrard, B., Hubert, P., & Rantanen, J. (August 2009). Quantitative in-line monitoring of pharmaceutical pellets active content using near infrared spectroscopy [Poster presentation]. 3rd Annual Pharmaceutical Solid State Research Cluster Symposium, Copenhagen, Denmark.

Mantanus, J., Ziemons, E., Streel, B., Klinkenberg, R., Evrard, B., Hubert, P., & Rantanen, J. (June 2009). Interfacing near infrared (NIR) spectroscopy with production line - Role of sample movement and density [Poster presentation]. Premier European Platform for Advancing Pharmaceutical Sciences, Nice, France.

Mantanus, J., Ziemons, E., & Hubert, P. (2009). Etablissement d'interfaces proche infrarouge adaptées à la nature du mouvement des pellets pharmaceutiques. (1).

Mantanus, J., Ziemons, E., Lebrun, P., Rozet, E., Klinkenberg, R., Streel, B., Evrard, B., & Hubert, P. (2009). Moisture content determination of pharmaceutical pellets by near infrared spectroscopy: method development and validation. Analytica Chimica Acta, 642 (1-2), 186-92. doi:10.1016/j.aca.2008.12.031
Peer Reviewed verified by ORBi

Rozet, E., Mantanus, J., Ziemons, E., Boulanger, B., Dewe, W., Crommen, J., & Hubert, P. (2009). Practical Implementation of Total Error for the Validation of Chromatographic and Ligand Binding Assays [Paper presentation]. PharmSciFair.

Ziemons, E., Mantanus, J., & Hubert, P. (2008). Détermination de la teneur en eau et de principes actifs dans des formulations pharmaceutiques à base de pellets par spectroscopie dans le proche infrarouge. (2).

Ziemons, E., Bourichi, H., Mantanus, J., Lebrun, P., Bouklouze, A., Cherrah, Y., & Hubert, P. (October 2008). Analyse quantitative de mélanges binaires de deux formes cristallines du fluconazole par la spectroscopie proche infrarouge et par diffraction des rayons X: comparaison des deux méthodes [Paper presentation]. 2ème Congrès des Sciences Analytiques, Casablanca, Morocco.

Ziemons, E., Mantanus, J., & Hubert, P. (2008). Détermination de la teneur en eau et de principes actifs dans des formulations pharmaceutiques à base de pellets par spectroscopie dans le proche infrarouge. (1).

Ziemons, E., Mantanus, J., Lebrun, P., Rozet, E., & Hubert, P. (2008). Reflexions, La Chimie Analytique Verte. (Planet'ULg, ULiège - Université de Liège). Reflexions.

Mantanus, J., Ziemons, E., Lebrun, P., Rozet, E., Klinkenberg, R., Streel, B., Evrard, B., & Hubert, P. (2008). Determination of moisture content in pharmaceutical pellets using near infrared spectroscopy: Method development and validation [Paper presentation]. PAT Workshop, Gent, Belgium.

Mantanus, J., Ziemons, E., Lebrun, P., Rozet, E., Klinkenberg, R., Streel, B., & Hubert, P. (2008). Moisture content determination of pharmaceutical pellets by near infrared spectroscopy: model selection, evaluation and validation [Poster presentation]. 11th Conference on Chemometrics in Analytical Chemistry, Montpellier, France.

Ziemons, E., Mantanus, J., & Hubert, P. (2008). PlanetULg, La Chimie Analytique Verte. (ULiège - Université de Liège).

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