  | Massoz, L., Bergemann, D., Lavergne, A., Reynders, C., Désiront, C., Goossens, C., Flasse, L., Peers, B., Voz, M., & Manfroid, I. (2023). Negative cell cycle regulation by Calcineurin is necessary for proper beta cell regeneration in zebrafish. eLife. doi:10.7554/elife.88813.1  Peer reviewed |
 | Streiff, C., Morvan, L., Zhang, H., Delrez, N., Fourrier, M., Manfroid, I., Suárez, N., Betoulle, S., Davison, A., Donohoe, O., & Vanderplasschen, A. (2023). Susceptibility and Permissivity of Zebrafish (Danio rerio) Larvae to Cypriniviruses. Viruses. doi:10.3390/v15030768 Peer Reviewed verified by ORBi |
Massoz, L., & Manfroid, I. (26 September 2022). Cell Cycle Negative Regulation of Pancreatic Ductal Progenitors by Calcineurin is Necessary for Proper Beta Cell Regeneration in Zebrafish [Poster presentation]. The molecular and cellular basis of regeneration and tissue repair, Barcelone, Spain. |
 | Reuter, A.-S., Stern, D., Bernard, A., Goossens, C., Lavergne, A., Flasse, L., Von Berg, V., Manfroid, I., Peers, B., & Voz, M. (14 March 2022). Identification of an evolutionarily conserved domain in Neurod1 favouring enteroendocrine versus goblet cell fate. PLoS Genetics, 18 (3), 1010109. doi:10.1371/journal.pgen.1010109 Peer Reviewed verified by ORBi |
 | Carril Pardo, C. A., Massoz, L., Dupont, M., Bergemann, D., Bourdouxhe, J., Lavergne, A., Tarifeño Saldivia, E., Helker, C. S., Stainier, D. Y. T., Peers, B., Voz, M., & Manfroid, I. (2022). A δ-cell subpopulation with pro-β cell identity contributes to efficient age-independent recovery in a zebrafish diabetes model. eLife, 11. doi:10.7554/eLife.67576 Peer Reviewed verified by ORBi |
Massoz, L., & Manfroid, I. (2022). Cell Cycle Negative Regulation of Pancreatic Ductal Progenitors by Calcineurin is Necessary for Proper Beta Cell Regeneration in Zebrafish [Poster presentation]. European Islet Study Group Workshop, Strasbourg, France. |
 | López-Pérez, A. R., Balwierz, P. J., Lenhard, B., Muller, F., Wardle, F. C., Manfroid, I., Voz, M., & Peers, B. (2021). Identification of downstream effectors of retinoic acid specifying the zebrafish pancreas by integrative genomics. Scientific Reports, 11 (1), 22717. doi:10.1038/s41598-021-02039-y Peer Reviewed verified by ORBi |
 | Massoz, L., Dupont, M., & Manfroid, I. (2021). Zebra-Fishing for Regenerative Awakening in Mammals. Biomedicines, 9 (1). doi:10.3390/biomedicines9010065 Peer Reviewed verified by ORBi |
  | Moortgat, S., Manfroid, I., Pendeville-Samain, H., Freeman, S., Bourdouxhe, J., Benoit, V., Merhi, A., Philippe, C., Faivre, L., & Maystadt, I. (2021). Broadening the phenotypic spectrum and physiological insights related to EIF2S3 variants. Human Mutation, 42 (7), 827-834. doi:10.1002/humu.24215 Peer Reviewed verified by ORBi |
Massoz, L., & Manfroid, I. (2020). Identification of a New Signaling Pathway Stimulating Beta Cell Regeneration from the Ducts : the Protein Phosphatase Calcineurin [Poster presentation]. From Stem Cells to Human Development. |
 | Lavergne, A., Tarifeño-Saldivia, E., Pirson, J., Reuter, A.-S., Flasse, L., Manfroid, I., Voz, M.* , & Peers, B.*. (2020). Pancreatic and intestinal endocrine cells in zebrafish share common transcriptomic signatures and regulatory programmes. BMC Biology, 18 (1), 109. doi:10.1186/s12915-020-00840-1 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
Manfroid, I. (28 August 2019). Discovery of somatostatin+ insulin+ bi-hormonal cells during beta cells regeneration in adult zebrafish and implication for diabetes disease [Paper presentation]. EdinFishTech. |
Carril Pardo, C. A., Bergemann, D., Massoz, L., Lavergne, A., Bourdouxhe, J., Peers, B., Voz, M., & Manfroid, I. (17 May 2019). Altered identity and function of the regenerated pancreatic ß-cells compared to control ß-cells in zebrafish [Poster presentation]. 2nd Interdisciplinary PhD Student Day organized by the EDT BCMB, Brussel, Belgium. |
Massoz, L., & Manfroid, I. (17 May 2019). Identification of Signaling Pathways regulating beta cell regeneration [Paper presentation]. Interuniversity PhD Student day, Bruxelles, Belgium. |
Manfroid, I. (07 October 2018). Characterization of regenerated beta cells in zebrafish [Paper presentation]. Islet Study Group 2018, Potsdam, Germany. |
Carril Pardo, C. A., Bergemann, D., Massoz, L., Lavergne, A., Bourdouxhe, J., Peers, B., Voz, M., & Manfroid, I. (04 June 2018). Pancreatic delta cells could be a new source of beta cells in adult zebrafish [Poster presentation]. f-TALES: A Roadmap towards Diabetes Treatment: To the Beta Cell and Beyond, Brussel, Belgium. |
 | Massoz, L., Bergemann, D., Lavergne, A., Bourdouxhe, J., Carril, C., Voz, M., Peers, B., & Manfroid, I. (June 2018). Insight into the Molecular Mechanisms of Pancreatic Beta Cell Regeneration from the Ducts in Zebrafish [Poster presentation]. F-tales congress : A Roadmap towards Diabetes Treatment: To the Beta Cell and Beyond. |
Lavergne, A., Tarifeno, E., Pirson, J., Bergemann, D., Voz, M., Manfroid, I., & Peers, B. (09 April 2018). Identification of Pax6-dependent regulatory networks during endocrine pancreatic cells and enteroendocrine cells differentiation in zebrafish [Poster presentation]. Next Generation Sequencing Conference 2018 - Structural Variation and Populations Genomics Conference, Barcelona, Spain. |
 | Demarez, C., Gerard, C., Cordi, S., Poncy, A., Achouri, Y., Dauguet, N., Rosa, D. A., Gunning, P. T., Manfroid, I., & Lemaigre, F. P. (2018). MiR-337-3p controls hepatobiliary gene expression and transcriptional dynamics during hepatic cell differentiation. Hepatology. doi:10.1002/hep.29475 Peer Reviewed verified by ORBi |
 | Bergemann, D., Massoz, L., Bourdouxhe, J., Carril Pardo, C., Voz, M., Peers, B., & Manfroid, I. (2018). Nifurpirinol : a more potent and reliable substrate compared to metronidazole for nitroreductase-mediated cell ablations. Wound Repair and Regeneration. doi:10.1111/wrr.12633 Peer Reviewed verified by ORBi |
Massoz, L., Bergemann, D., Lavergne, A., Bourdouxhe, J., Carril Pardo, C., Peers, B., Voz, M., & Manfroid, I. (15 September 2017). Identification of Signaling Pathways Regulating Beta Cell Regeneration in Zebrafish [Poster presentation]. BSCDB Cell differentiation in normal and pathological conditions, Woluwe, Belgium. |
Lavergne, A., Tarifeno, E., Pirson, J., Bergemann, D., Voz, M., Manfroid, I., & Peers, B. (14 September 2017). Identification of Pax6-dependent regulatory networks during endocrine pancreatic cells and enteroendocrine cells differentiation in zebrafish [Poster presentation]. Cell differentiation in normal and pathological conditions, Woluwe, Belgium. |
Carril Pardo, C. A., Bergemann, D., Massoz, L., Lavergne, A., Bourdouxhe, J., Peers, B., Voz, M., & Manfroid, I. (14 September 2017). Toward discovery of novel key genes for pancreatic beta cell regeneration in zebrafish [Poster presentation]. BSCDB Cell differentiation in normal and pathological conditions, Woluwe, Belgium. |
 | Bergemann, D., Massoz, L., Bourdouxhe, J., Peers, B., Voz, M., & Manfroid, I. (July 2017). Beta Cell Regeneration in Zebrafish : Investigating the Ductal Contribution [Poster presentation]. 10th European Zebrafish Meeting, Budapest, Hungary. |
 | Tarifeño Saldivia, E., Lavergne, A., Bernard, A., Padamata, K., Bergemann, D., Voz, M., Manfroid, I., & Peers, B. (21 March 2017). Transcriptome analysis of pancreatic cells across distant species highlights novel important regulator genes. BMC Biology, 15. doi:10.1186/s12915-017-0362-x Peer Reviewed verified by ORBi |
Tarifeño-Saldivia, E., Lavergne, A., Bernard, A., Padamata, K., Bergemann, D., Voz, M., Manfroid, I., & Peers, B. (21 March 2017). Transcriptome analysis of pancreatic cells across distant species highlights novel important regulator genes [Paper presentation]. 7th meeting IAPVII-07 DevRepair, Leuven, Belgium. |
 | DELHEZ, A., Manfroid, I., LEFEBVRE, P., Delacroix, L., & Malgrange, B. (2017). Potential use of estetrol in sensorineural hearing loss protection. B-ENT. Peer Reviewed verified by ORBi |
Manfroid, I. (09 December 2016). Zebrafish: a small fish to tackle alternative routes toward anti-diabetic treatments [Paper presentation]. ISV-meetings. |
Manfroid, I. (09 December 2016). Pancreatic cell differentiation, plasticity and beta cell regeneration [Paper presentation]. Friday Lectures, Life Sciences Institute, Université Catholique de Louvain. |
Manfroid, I. (18 September 2016). Beta cell regeneration from pancreatic ducts in adult zebrafish [Poster presentation]. ISG 2016 – The Islet Study Group. |
Tarifeño Saldivia, E., Lavergne, A., Padamata, K., Bernard, A., Voz, M., Manfroid, I., & Peers, B. (July 2016). Transcriptional landscape of the major pancreatic cells reveals conserved expression patterns amongst distant vertebrate species [Poster presentation]. 12TH INTERNATIONAL CONFERENCE ON ZEBRAFISH DEVELOPMENT AND GENETICS, Orlando, United States. |
DELHEZ, A., Manfroid, I., LEFEBVRE, P., Delacroix, L., & Malgrange, B. (18 May 2016). In vivo and in vitro studies on estetrol for prevention and treatment of sensorineural hearing loss [Poster presentation]. Molecular Biology of hearing and deafness, Cambridge, United Kingdom. |
 | Bergemann, D., Ghaye, A., Tarifeño Saldivia, E., Lavergne, A., Bourdouxhe, J., Peers, B., Voz, M., & Manfroid, I. (18 March 2016). Pancreatic Beta Cell Regeneration: Duct Cells Act as Progenitors in Adult Zebrafish [Poster presentation]. International Fishmed Conference on Zebrafish Research, Warsaw, Poland. |
 | Bergemann, D., Ghaye, A., Tarifeño, E., Peers, B., Voz, M., & Manfroid, I. (November 2015). Pancreatic Beta Cell Regeneration: Duct Cells act as Progenitors in Adult Zebrafish [Poster presentation]. utumn meeting organized by the Belgian Society for Cell and Developmental Biology, FWO-Flanders and Belspo IUAP/PAI-07 network DevRepair on " Developmental programming and organ repair", Leuven, Belgium. |
 | Ghaye, A., Bergemann, D., Tarifeño Saldivia, E., Flasse, L., Von Berg, V., Peers, B., Voz, M.* , & Manfroid, I.*. (02 September 2015). Progenitor potential of nkx6.1-expressing cells throughout zebrafish life and during beta cell regeneration. BMC Biology, 13, 70. doi:10.1186/s12915-015-0179-4 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
Bergemann, D., & Manfroid, I. (08 December 2014). Towards the Identification of Molecular Mechanisms Underlying Pancreatic Beta Cell Regeneration in Zebrafish [Paper presentation]. 5th IUAP network meeting - DevRepair, Rotterdam, Netherlands. |
Manfroid, I. (13 September 2014). Transcriptomic characterization of pancreatic duct cells in adult zebrafish [Poster presentation]. ISG2014 "Pancreatic Islet Plasticity in Health and Diabetes", Lausanne, Switzerland. |
 | Flasse, L., Pirson, J., Stern, D., Von Berg, V., Manfroid, I., Peers, B., & Voz, M. (July 2013). Ascl1b and Neurod1, instead of Neurog3, control pancreatic endocrine cell fate in zebrafish. BMC Biology, 11, 78. doi:10.1186/1741-7007-11-78 Peer Reviewed verified by ORBi |
Manfroid, I., Tarifeño Saldivia, E., Voz, M., & Peers, B. (27 May 2013). Characterization of the zebrafish beta-cell transcriptome by RNA-seq [Poster presentation]. EMBO Workshop on Liver an Pancreas Development, Function and Disease. |
Manfroid, I. (21 March 2013). From hepatopancreatic duct formation to b-cell regeneration in zebrafish [Paper presentation]. séminaires invités institut de Duve, UCL. |
 | Flasse, L., Stern, D., Pirson, J., Manfroid, I., Peers, B., & Voz, M. (2013). The bHLH transcription factor Ascl1a is essential for the specification of the intestinal secretory cells and mediates Notch signaling in the zebrafish intestine. Developmental Biology, 376 (2), 187-97. doi:10.1016/j.ydbio.2013.01.011 Peer Reviewed verified by ORBi |
 | Naye, F., Voz, M., Detry, N., Hammerschmidt, M., Peers, B., & Manfroid, I. (2012). Essential roles of zebrafish bmp2a, fgf10 and fgf24 in the specification of the ventral pancreas. Molecular Biology of the Cell. doi:10.1091/mbc.E11-08-0664 Peer Reviewed verified by ORBi |
 | Manfroid, I., Ghaye, A., Naye, F., Detry, N., Palm, S., Pan, L., Ma, T., Huang, W., Rovira, M., Martial, J., Parsons, M., Moens, C., Voz, M., & Peers, B. (2012). Zebrafish sox9b is crucial for hepatopancreatic duct development and pancreatic endocrine cell regeneration. Developmental Biology. doi:10.1016/j.ydbio.2012.04.002 Peer Reviewed verified by ORBi |
Laudadio, I., Manfroid, I., Achouri, Y., Schmidt, D., Wilson, M. D., Cordi, S., Thorrez, L., Knoops, L., Jacquemin, P., Schuit, F., Pierreux, C. E., Odom, D. T., Peers, B., & Lemaigre, F. P. (2012). A feedback loop between the liver-enriched transcription factor network and mir-122 controls hepatocyte differentiation. Gastroenterology, 142 (1), 119-29. doi:10.1053/j.gastro.2011.09.001 Peer Reviewed verified by ORBi |
 | Djiotsa, J., Verbruggen, V., Giacomotto, J., Ishibashi, M., Manning, E., Rinkwitz, S., Manfroid, I., Voz, M., & Peers, B. (2012). Pax4 is not essential for beta-cell differentiation in zebrafish embryos but modulates alpha-cell generation by repressing arx gene expression. BMC Developmental Biology, 12, 37. doi:10.1186/1471-213X-12-37 Peer Reviewed verified by ORBi |
 | Voz, M., Coppieters, W., Manfroid, I., Baudhuin, A., Von Berg, V., Charlier, C., Meyer, D., Driever, W., Martial, J., & Peers, B. (2012). Fast Homozygosity Mapping and Identification of a Zebrafish ENU-Induced Mutation by Whole-Genome Sequencing. PLoS ONE, 7 (4), 34671. doi:10.1371/journal.pone.0034671 Peer Reviewed verified by ORBi |
Manfroid, I. (May 2011). Rapid and efficient identification of zebrafish ENU-induced mutations by whole-genome sequencing [Poster presentation]. Joint BOLD ZF-HEALTH Meeting, Karlsruhe, Germany. |
 | Verbruggen, V., Ek, O., Georlette, D., Delporte, F., Von Berg, V., Detry, N., Biemar, F., Coutinho, P., Martial, J., Voz, M., Manfroid, I., & Peers, B. (30 April 2010). The Pax6b homeodomain is dispensable for pancreatic endocrine cell differentiation in zebrafish. Journal of Biological Chemistry, 285 (18), 13863-73. doi:10.1074/jbc.M110.108019 Peer Reviewed verified by ORBi |
 | Binot, A.-C., Manfroid, I., Flasse, L., Winandy, M., Motte, P., Martial, J., Peers, B., & Voz, M. (01 February 2010). Nkx6.1 and nkx6.2 regulate alpha- and beta-cell formation in zebrafish by acting on pancreatic endocrine progenitor cells. Developmental Biology, 340 (2), 397-407. doi:10.1016/j.ydbio.2010.01.025 Peer Reviewed verified by ORBi |
Manfroid, I. (January 2010). Zebrafish sox9b is essential for hepatopancreatic ductal system differentiation and morphogenesis [Paper presentation]. BetaCellTherapy workshop, Brussels, Belgium. |
Manfroid, I. (October 2009). Dissecting the role of sox9b in hepatopancreatic development in zebrafish [Poster presentation]. Mechanisms of Organ Regeneration in Model Systems, Biomedicine Workshop, Baeza, Spain. |
 | Delporte, F. M., Pasque, V., Devos, N., Manfroid, I., Voz, M., Motte, P., Biemar, F., Martial, J., & Peers, B. (2008). Expression of zebrafish pax6b in pancreas is regulated by two enhancers containing highly conserved cis-elements bound by PDX1, PBX and PREP factors. BMC Developmental Biology, 8, 53. doi:10.1186/1471-213X-8-53 Peer Reviewed verified by ORBi |
Pendeville-Samain, H., Winandy, M., Manfroid, I., Nivelles, O., Motte, P., Pasque, V., Peers, B., Struman, I., Martial, J., & Voz, M. (2008). Zebrafish Sox7 and Sox18 function together to control arterial-venous identity. Developmental Biology, 317 (2), 405-16. doi:10.1016/j.ydbio.2008.01.028 Peer Reviewed verified by ORBi |
Manfroid, I. (July 2007). FGF cross-talks between endoderm and mesoderm control the formation of the ventral pancreatic bud in zebrafish [Poster presentation]. 5th European Zebrafish Genetics and Development Meeting, Amsterdam, Netherlands. |
 | Manfroid, I., Delporte, F., Baudhuin, A., Motte, P., Neumann, C. J., Voz, M., Martial, J., & Peers, B. (2007). Reciprocal endoderm-mesoderm interactions mediated by fgf24 and fgf10 govern pancreas development. Development, 134 (22), 4011-21. doi:10.1242/dev.007823 Peer Reviewed verified by ORBi |
Manfroid, I. (October 2006). Role of the lateral mesoderm and FGF signaling in the formation of the ventral pancreatic bud in zebrafish [Paper presentation]. Programming Beta Cell Development, Impairment and Regeneration Workshop 2006, El Perello, Spain. |
 | Manfroid, I., Caubit, X., Marcelle, C., & Fasano, L. (October 2006). Teashirt 3 expression in the chick embryo reveals a remarkable association with tendon development. Gene Expression Patterns, 6 (8), 908-912. doi:10.1016/j.modgep.2006.03.004 Peer Reviewed verified by ORBi |
 | Manfroid, I., Van de Weerdt, C., Baudhuin, A., Martial, J., & Muller, M. (2005). EGF stimulates Pit-1 independent transcription of the human prolactin pituitary promoter in human breast cancer SK-BR-3 cells through its proximal AP-1 response element. Molecular and Cellular Endocrinology, 229 (1-2), 127-39. doi:10.1016/j.mce.2004.08.009 Peer Reviewed verified by ORBi |
 | Manfroid, I. (March 2004). Three putative murine Teashirt orthologues specify trunk structures in Drosophila in the same way as the Drosophila teashirt gene. Development, 131. doi:10.1242/dev.00977 Peer Reviewed verified by ORBi |
 | Quentien, M. H., Manfroid, I., Moncet, D., Gunz, G., Muller, M., Grino, M., Enjalbert, A., & Pellegrini, I. (15 November 2002). Pitx factors are involved in basal and hormone-regulated activity of the human prolactin promoter. Journal of Biological Chemistry, 277 (46), 44408-44416. doi:10.1074/jbc.M207824200 Peer Reviewed verified by ORBi |
 | Baudhuin, A., Manfroid, I., Van de Weerdt, C., Martial, J., & Muller, M. (November 2002). Transcription of the human prolactin gene in mammary cells. Annals of the New York Academy of Sciences, 973, 454-458. doi:10.1111/j.1749-6632.2002.tb04682.x Peer Reviewed verified by ORBi |
 | Manfroid, I., Martial, J., & Muller, M. (2001). Inhibition of protein phosphatase PP1 in GH3B6, but not in GH3 cells, activates the MEK/ERK/c-fos pathway and the human prolactin promoter, involving the coactivator CPB/p300. Molecular Endocrinology, 15 (4), 625-37. doi:10.1210/mend.15.4.0615 Peer Reviewed verified by ORBi |
 | Sohm, F., Manfroid, I., Pezet, A., Rentier-Delrue, F., Rand-Weaver, M., Kelly, P. A., Boeuf, G., Postel-Vinay, M. C., de Luze, A., & Edery, M. (1998). Identification and modulation of a growth hormone-binding protein in rainbow trout (Oncorhynchus mykiss) plasma during seawater adaptation. General and Comparative Endocrinology, 111 (2), 216-24. doi:10.1006/gcen.1998.7106 Peer Reviewed verified by ORBi |
Muller, M., Berwaer, M., Caccavelli, L., Manfroid, I., Nalda, A., Pendeville-Samain, H., Pernasetti, F., Van de Weerdt, C., Peers, B., & Martial, J. (1998). Régulation transcriptionnelle du gène de la prolactine humaine. MS. Medecine Sciences, 14 (580-587). doi:10.4267/10608/1096 Peer Reviewed verified by ORBi |
 | Caccavelli, L., Manfroid, I., Martial, J., & Muller, M. (1998). Transcription factor AP1 is involved in basal and okadaic acid-stimulated activity of the human PRL promoter. Molecular Endocrinology, 12 (8), 1215-27. doi:10.1210/mend.12.8.0152 Peer Reviewed verified by ORBi |