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Bajou Khalid

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Main Referenced Co-authors
Noël, Agnès  (28)
Foidart, Jean-Michel  (26)
Martial, Joseph  (11)
Blacher, Silvia  (10)
Masson, Véronique  (10)
Main Referenced Keywords
angiogenesis (10); PAI-1 (6); serine protease (5); proteolysis (3); cancer invasion (2);
Main Referenced Unit & Research Centers
GIGA-I3 - Giga-Infection, Immunity and Inflammation - ULiège [BE] (1)
Giga-Cancer - ULiège [BE] (1)
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (29)
Oncology (6)
Ophthalmology (2)
Cardiovascular & respiratory systems (1)
General & internal medicine (1)

Publications (total 39)

The most downloaded
837 downloads
Bajou, K., Noël, A., Gerard, R. D., Masson, V., Brunner, N., Holst-Hansen, C., Skobe, M., Fusenig, N. E., Carmeliet, P., Collen, D., & Foidart, J.-M. (August 1998). Absence of Host Plasminogen Activator Inhibitor 1 Prevents Cancer Invasion and Vascularization. Nature Medicine, 4 (8), 923-8. doi:10.1038/nm0898-923 https://hdl.handle.net/2268/17458

The most cited

625 citations (Scopus®)

Bajou, K., Noël, A., Gerard, R. D., Masson, V., Brunner, N., Holst-Hansen, C., Skobe, M., Fusenig, N. E., Carmeliet, P., Collen, D., & Foidart, J.-M. (August 1998). Absence of Host Plasminogen Activator Inhibitor 1 Prevents Cancer Invasion and Vascularization. Nature Medicine, 4 (8), 923-8. doi:10.1038/nm0898-923 https://hdl.handle.net/2268/17458

Herkenne, S., Paques, C., Nivelles, O., Lion, M., BAJOU, K., Pollenus, T., Fontaine, M., Carmeliet, P., Martial, J., Nguyen, N.-Q.-N., & Struman, I. (2015). The interaction of uPAR with VEGFR2 promotes VEGF-induced angiogenesis. Science Signaling, 8 (403), 117. doi:10.1126/scisignal.aaa2403
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Amand, M., Erpicum, C., BAJOU, K., Cerignoli, F., Blacher, S., MARTIN, M., Dequiedt, F., Drion, P., Singh, P., Vandereyken, M., Musumeci, L., Moutschen, M., Gilles, C., Noël, A., & Rahmouni, S. (27 January 2014). DUSP3/VHR is a pro-angiogenic atypical dual-specificity phosphatase [Poster presentation]. GIGA Day 2014, Liège, Belgium.

Bajou, K.* , Herkenne, S.* , Thijssen, V. L., D'Amico, S., Nguyen, N.-Q.-N., Bouche, A., Tabruyn, S., Srahna, M., Carabin, J.-Y., Nivelles, O., Paques, C., Cornelissen, Y., Lion, M., Noël, A., Gils, A., Vinckier, S., Declerck, P. J., Griffioen, A. W., Dewerchin, M., ... Struman, I. (2014). PAI-1 mediates the antiangiogenic and profibrinolytic effects of 16K prolactin. Nature Medicine, (7), 741. doi:10.1038/nm.3552
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* These authors have contributed equally to this work.

Amand, M., Erpicum, C., BAJOU, K., Cerignoli, F., Blacher, S., Martin, M., Dequiedt, F., Drion, P., Singh, P., Zurashvili, T., Vandereyken, M., Musumeci, L., Mustelin, T., Moutschen, M., Gilles, C., Noël, A., & Rahmouni, S. (2014). DUSP3/VHR is a pro-angiogenic atypical dual-specificity phosphatase. Molecular Cancer. doi:10.1186/1476-4598-13-108
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Herkenne, S., Bajou, K., Nguyen, N.-Q.-N., Martial, J., & Struman, I. (19 May 2012). Implication of the PAI-1/uPA/uPAR signalosome in the antiangiogenic action of 16K prolactin [Poster presentation]. GIGA-Cancer Day, Liège, Belgium.

Herkenne, S., Dalla Valle, A., Bajou, K., Nguyen, N.-Q.-N., Martial, J., & Struman, I. (April 2012). Implication of the PAI-1/uPA/uPAR complex in the antiangiogenic action of 16K prolactin [Poster presentation]. Biomedica, Liège, Belgium.

Herkenne, S., Dalla Valle, A., Bajou, K., Nguyen, N.-Q.-N., Martial, J., & Struman, I. (2012). Implication of the PAI-1/uPA/uPAR complex in the antiangiogenic action of 16K hPRL [Poster presentation]. Keystone symposia on Angiogenesis: Advances in Basic Science and Therapeutic Applications, Snowbird, United States - Utah.

Struman, I., Martial, J., Bajou, K., & D'Amico, S. (25 August 2011). A pharmaceutical composition for treatment of thrombosis-related diseases comprising a fragment of prolactin (PRL)-growth hormone (GH) – placental lactogen (PL)-family protein.

Herkenne, S., Bajou, K., D'Amico, S., Nguyen, N.-Q.-N., Martial, J., & Struman, I. (2011). Implication of the PAI-1/uPA/uPAR complex in the effects of the antiangiogenic factor 16K hPRL [Poster presentation]. Giga cancer day, Liège, Belgium.

Bajou, K., Herkenne, S., Thijssen, V. L., D'Amico, S., Srahna, M., Carabin, J.-Y., Gils, A., Declerck, P. J., Griffioen, A. W., Martial, J., & Struman, I. (January 2011). PAI-1 mediates antiangiogenic and fibrinolytic actions of prolactin/growth hormone 16-14K fragments [Poster presentation]. Giga-Day Symposia, Liège, Belgium.

Herkenne, S., Bajou, K., D'Amico, S., Martial, J., & Struman, I. (21 May 2010). Study of the signalling pathway of 16K PRL and 14K GH for mediate their anti-angiogenic effect [Poster presentation]. GIGA-Cancer Day, Liège, Belgium.

Kinet, V., Nguyen, N.-Q.-N., Sabatel, C., Bajou, K., Blacher, S., Noël, A., Martial, J., & Struman, I. (2009). Evaluation of the antitumor activity of 16K prolactin [Poster presentation]. Keystone symposia: angiogenesis and lymphangiogenesis in cancer, Big Sky, United States - Montana.

Bajou, K., Peng, H., Laug, W. E., Maillard, C., Noël, A., Foidart, J.-M., Martial, J., & Declerck, Y. A. (2008). Plasminogen activator inhibitor-1 protects endothelial cells from FasL-mediated apoptosis. Cancer Cell, 14 (4), 324-34. doi:10.1016/j.ccr.2008.08.012
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Jost, M., Maillard, C., Lecomte, J., Lambert, V., Tjwa, M., Blaise, P., Alvarez Gonzalez, M.-L., Bajou, K., Blacher, S., Motte, P., Humblet, C., Defresne, M.-P., Thiry, M., Frankenne, F., Gothot, A., Carmeliet, P., Rakic, J.-M., Foidart, J.-M., & Noël, A. (2007). Tumoral and choroidal vascularization: differential cellular mechanisms involving plasminogen activator inhibitor type I. American Journal of Pathology, 171 (4), 1369-80. doi:10.2353/ajpath.2007.070074
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Jost, M., Maillard, C., Lambert, V., Tjwa, M., Blaise, P., Lecomte, J., Bajou, K., Blacher, S., Motte, P., Humblet, C., Defresne, M.-P., Thiry, M., Frankenne, F., Gothot, A., Carmeliet, P., Rakic, J.-M., Foidart, J.-M., & Noël, A. (2006). Plasminogen activator inhibitor type I (PAI-1) controls bone marrow-dependent and independent vascularization. Acta Clinica Belgica, 61 (2, MAR-APR), 87.
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Jost, M., Maillard, C., Lecomte, J., Lambert, V., Tjwa, M., Blaise, P., Alvarez Gonzalez, M.-L., Bajou, K., Blacher, S., Motte, P., Humblet, C., Defresne, M.-P., Thiry, M., Frankenne, F., Gothot, A., Carmeliet, P., RAKIC, J.-M., Foidart, J.-M., & Noël, A. (2006). Plasminogen activator inhibitor type 1 (PAI-1) controls bone marrow-dependent and independent vascularization [Poster presentation]. Meeting ABEC/BVSK.

Masson, V., de la Ballina, L. R., Munaut, C., Wielockx, B., Jost, M., Maillard, C., Blacher, S., Bajou, K., Itoh, T., Itohara, S., Werb, Z., Libert, C., Foidart, J.-M., & Noël, A. (February 2005). Contribution of Host MMP-2 and MMP-9 to Promote Tumor Vascularization and Invasion of Malignant Keratinocytes. FASEB Journal, 19 (2), 234-6. doi:10.1096/fj.04-2140fje
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Maillard, C., Jost, M., Romer, M. U., Brunner, N., Houard, X., Lejeune, A., Munaut, C., Bajou, K., Melen-Lamalle, L., Dano, K., Carmeliet, P., Fusenig, N. E., Foidart, J.-M., & Noël, A. (January 2005). Host plasminogen activator inhibitor-1 promotes human skin carcinoma progression in a stage-dependent manner. Neoplasia, 7 (1), 57-66. doi:10.1593/neo.04406
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Bajou, K., Maillard, C., Jost, M., Lijnen, R. H., Gils, A., Declerck, P., Carmeliet, P., Foidart, J.-M., & Noël, A. (09 September 2004). Host-derived plasminogen activator inhibitor-1 (PAI-1) concentration is critical for in vivo tumoral angiogenesis and growth. Oncogene, 23 (41), 6986-6990. doi:10.1038/sj.onc.1207859
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Rakic, J.-M., Lambert, V., Munaut, C., Bajou, K., Peyrollier, K., Alvarez Gonzalez, M.-L., Carmeliet, P., Foidart, J.-M., & Noël, A. (April 2003). Mice without uPA, tPA, or plasminogen genes are resistant to experimental choroidal neovascularization. Investigative Ophthalmology and Visual Science, 44 (4), 1732-1739. doi:10.1167/iovs.02-0809
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Rakic, J.-M., Maillard, C., Jost, M., Bajou, K., Masson, V., Devy, L., Lambert, V., Foidart, J.-M., & Noël, A. (March 2003). Role of plasminogen activator-plasmin system in tumor angiogenesis. Cellular and Molecular Life Sciences, 60 (3), 463-473. doi:10.1007/s000180300039
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Masson, V., Devy, L., Grignet, C., Berndt, S., Bajou, K., Blacher, S., Roland, G., Chang, Y., Fong, T., Carmeliet, P., Foidart, J.-M., & Noël, A. (28 October 2002). Mouse Aortic Ring Assay: A New Approach of the Molecular Genetics of Angiogenesis. Biological Procedures Online, 4, 24-31. doi:10.1251/bpo30
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Bajou, K., Lewalle, J. M., Martinez, C. R., Soria, C., Lu, H., Noël, A., & Foidart, J.-M. (10 August 2002). Human breast adenocarcinoma cell lines promote angiogenesis by providing cells with uPA-PAI-1 and by enhancing their expression. International Journal of Cancer, 100 (5), 501-506. doi:10.1002/ijc.10487
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Devy, L., Blacher, S., Grignet, C., Bajou, K., Masson, V., Gerard, R. D., Gils, A., Carmeliet, G., Carmeliet, P., Declerck, P. J., Noël, A., & Foidart, J.-M. (February 2002). The pro- or antiangiogenic effect of plasminogen activator inhibitor 1 is dose dependent. FASEB Journal, 16 (2), 147-54. doi:10.1096/fj.01-0552com
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Hajitou, A., Grignet, C., Devy, L., Berndt, S., Blacher, S., Deroanne, C., Bajou, K., Fong, T., Chiang, Y. W., Foidart, J.-M., & Noël, A. (2002). The antitumoral effect of endostatin and angiostatin is associated with a down-regulation of vascular endothelial growth factor expression in tumor cells. FASEB Journal, 16, 1802-1804. doi:10.1096/fj.02-0109fje
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Noël, A., Albert, V., Bajou, K., Bisson, C., Devy, L., Frankenne, F., Maquoi, E., Masson, V., Sounni, N. E., & Foidart, J.-M. (April 2001). New Functions of Stromal Proteases and Their Inhibitors in Tumor Progression. Surgical Oncology Clinics of North America, 10 (2), 417-32. doi:10.1016/s1055-3207(18)30073-5
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Lambert, V., Munaut, C., Frankenne, F., Bajou, K., Gerard, R., Carmeliet, P., Defresne, M.-P., Foidart, J.-M., Rakic, J.-M., & Noël, A. (April 2001). Influence of Plasminogen Activator Inhibitor Type 1 on Choroidal Neovascularization. FASEB Journal, 15 (6), 1021-7. doi:10.1096/fj.00-0393com
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Bajou, K., Masson, V., Gerard, R. D., Schmitt, P. M., Albert, V., Praus, M., Lund, L. R., Frandsen, T. L., Brunner, N., Dano, K., Fusenig, N. E., Weidle, U., Carmeliet, G., Loskutoff, D., Collen, D., Carmeliet, P., Foidart, J.-M., & Noël, A. (10 February 2001). The Plasminogen Activator Inhibitor PAI-1 Controls in Vivo Tumor Vascularization by Interaction with Proteases, Not Vitronectin. Implications for Antiangiogenic Strategies. Journal of Cell Biology, 152 (4), 777-84. doi:10.1083/jcb.152.4.777
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Bajou, K., Devy, L., Masson, V., Albert, V., Frankenne, F., Noël, A., & Foidart, J.-M. (2001). Role de l'inhibiteur des activateurs de plasminogene de type 1 dans l'angiogenese tumorale. Thérapie, 56 (5, Sep-Oct), 465-72.
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Frankenne, F., Noël, A., Bajou, K., Sounni, N. E., Goffin, F., Masson, V., Munaut, C., Remacle, A., & Foidart, J.-M. (September 1999). Molecular interactions involving urokinase plasminogen activator (uPA), its receptor (uPAR) and its inhibitor, plasminogen activator inhibitor-1 (PAI-1), as new targets for tumour therapy. Expert Opinion on Therapeutic Targets, 3 (3), 469-481 (13. doi:10.1517/14728222.3.3.469
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Noël, A., Bajou, K., Masson, V., Frankenne, F., Rakic, J.-M., Lambert, V., Carmeliet, P., & Foidart, J.-M. (1999). Regulation of cancer invasion and vascularization by plasminogen activator inhibitor-1. Fibrinolysis and Proteolysis, 13 (6), 220-225. doi:10.1054/fipr.2000.0043
Peer reviewed

Hajitou, A., Baramova, E., Bajou, K., Noë, V., Bruyneel, E., Mareel, M., Collette, J., Foidart, J.-M., & Calberg-Bacq, C.-M. (22 October 1998). Fgf-3 and Fgf-4 Elicit Distinct Oncogenic Properties in Mouse Mammary Myoepithelial Cells. Oncogene, 17 (16), 2059-71. doi:10.1038/sj.onc.1202126
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Bajou, K., Noël, A., Gerard, R. D., Masson, V., Brunner, N., Holst-Hansen, C., Skobe, M., Fusenig, N. E., Carmeliet, P., Collen, D., & Foidart, J.-M. (August 1998). Absence of Host Plasminogen Activator Inhibitor 1 Prevents Cancer Invasion and Vascularization. Nature Medicine, 4 (8), 923-8. doi:10.1038/nm0898-923
Peer Reviewed verified by ORBi

Lewalle, J. M., Cataldo, D., Bajou, K., Lambert, C. A., & Foidart, J.-M. (January 1998). Endothelial Cell Intracellular Ca2+ Concentration Is Increased Upon Breast Tumor Cell Contact and Mediates Tumor Cell Transendothelial Migration. Clinical and Experimental Metastasis, 16 (1), 21-9. doi:10.1023/A:1006555800862
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Lewalle, J. M., Bajou, K., Desreux, J., Mareel, M., Dejana, E., Noël, A., & Foidart, J.-M. (15 December 1997). Alteration of Interendothelial Adherens Junctions Following Tumor Cell-Endothelial Cell Interaction in Vitro. Experimental Cell Research, 237 (2), 347-56. doi:10.1006/excr.1997.3799
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Baramova, E. N., Bajou, K., Remacle, A., L'Hoir, C., Krell, H. W., Weidle, U. H., Noël, A., & Foidart, J.-M. (24 March 1997). Involvement of Pa/Plasmin System in the Processing of Pro-Mmp-9 and in the Second Step of Pro-Mmp-2 Activation. FEBS Letters, 405 (2), 157-62. doi:10.1016/S0014-5793(97)00175-0
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Devy, L., Noël, A., Baramova, E. N., Bajou, K., Trentesaux, C., Jardillier, J. C., Foidart, J.-M., & Jeannesson, P. (1997). Production and activation of matrix metalloprotease-9 (MMP-9) by HL-60 promyelocytic leukemia cells. Biochemical and Biophysical Research Communications, 238, 842-846. doi:10.1006/bbrc.1997.7398
Peer reviewed

Noël, A., Gilles, C., Bajou, K., Devy, L., Kebers, F., Lewalle, J. M., Maquoi, E., Munaut, C., Remacle, A., & Foidart, J.-M. (1997). Emerging Roles for Proteinases in Cancer. Invasion and Metastasis, 17 (5), 221-39.
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Michiels, C., Arnould, T., Janssens, D., Bajou, K., Geron, I., & Remacle, R. (June 1996). Interactions between endothelial cells and smooth muscle cells after their activation by hypoxia. A possible etiology for venous disease. International Angiology: A Journal of the International Union of Angiology, 15 (5), 124-130.
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