  | Beguin, C., Kwan, O., Ritacco, C., Debray, J.-C., Dejardin, E., Dubois, S., Köse, M. C., Canti, L., Courtois, J., Seidel, L., Daulne, C., Caers, J., Beguin, Y., Ehx, G., & Baron, F. (17 November 2023). TNF-α priming of human regulatory T cells does not increase their ability to prevent xenogeneic graft-versus-host disease [Paper presentation]. Congrès annuel de la Société Francophone de Greffe de Moelle et Thérapie Cellulaire, Lille, France.  Peer reviewed |
  | Beauvois, A.* , Gazon, H.* , Chauhan, P. S., Jamakhani, M., Jacques, J.-R., Thiry, M., Dejardin, E., Di Valentin, E., Twizere, J.-C., Péloponèse, J.-M., Njock, M.-S., Yasunaga, J.-I., Matsuoka, M., Hamaïdia, M.* , & Willems, L.*. (2023). The helicase-like transcription factor redirects the autophagic flux and restricts human T-cell leukemia virus type 1 infection. Proceedings of the National Academy of Sciences of the United States of America, 120 (31), 2216127120. doi:10.1073/pnas.2216127120 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
Lion, Q., Wen, X., Shostak, K., Vanleyssem, R., Close, P., Dejardin, E., & Chariot, A. (06 September 2022). ROLE OF THE tRNA-MODIFYING ENZYME ELONGATOR IN LIVER [Poster presentation]. GIGA DAY 2022. |
 | Faure-Dupuy, S., Riedl, T., Rolland, M., Hizir, Z., Reisinger, F., Neuhaus, K., Schuehle, S., Remouchamps, C., Gillet, N., Schönung, M., Stadler, M., Wettengel, J., Barnault, R., Parent, R., Schuster, L. C., Farhat, R., Prokosch, S., Leuchtenberger, C., Öllinger, R., ... Heikenwälder, M.*. (December 2021). Control of APOBEC3B induction and cccDNA decay by NF-κB and miR-138-5p. JHEP Reports, 3 (6), 100354. doi:10.1016/j.jhepr.2021.100354 Peer reviewed* These authors have contributed equally to this work. |
 | Riedl, T., Faure-Dupuy, S., Rolland, M., Schuehle, S., Hizir, Z., Calderazzo, S., Zhuang, X., Wettengel, J., Lopez, M., Barnault, R., Mirakaj, V., Prokosch, S., Heide, D., Leuchtenbergeg, C., Schneider, M., Heßling, B., Stottmeier, B., Wessbecher, I. M., Schirmacher, P., ... Heikenwalder, M. (2021). HIF1α-mediated RelB/APOBEC3B downregulation allows Hepatitis B Virus persistence. Hepatology (Baltimore, Md.). doi:10.1002/hep.31902 Peer reviewed* These authors have contributed equally to this work. |
 | Namineni, S., O'Connor, T., Faure-Dupuy, S., Johansen, P., Riedl, T., Liu, K., Xu, H., Singh, I., Shinde, P., Li, F., Pandyra, A., Sharma, P., Ringelhan, M., Muschaweckh, A., Borst, K., Blank, P., Lampl, S., Durantel, D., Farhat, R., ... Heikenwalder, M. (2020). A dual role for hepatocyte-intrinsic canonical NF-kappaB signaling in virus control. Journal of Hepatology. doi:10.1016/j.jhep.2019.12.019 Peer Reviewed verified by ORBi |
 | Conlon, T., John-Schuster, G., Heide, D., Pfister, D., Lehmann, M., Hu, Y., Ertuz, Z., Lopez, M., Ansari, M., Strunz, M., Mayr, C., Cimineiri, C., Costa, R., Kohlhepp, M. S., Guillot, A., Günes, G., Jeridi, A., Funk, M., Beroshvili, G., ... Yildirim, A. Ö. (2020). Inhibition of LTβR-signalling activates Wnt-induced regeneration in lung. Nature. doi:10.1038/s41586-020-2882-8 Peer Reviewed verified by ORBi |
 | Tanghe, G., Urwyler-Rosselet, C., De Groote, P., Dejardin, E., De Bock, P.-J., Gevaert, K., Vandenabeele, P., & Declercq, W. (2018). RIPK4 activity in keratinocytes is controlled by the SCF(beta-TrCP) ubiquitin ligase to maintain cortical actin organization. Cellular and Molecular Life Sciences. doi:10.1007/s00018-018-2763-6 Peer Reviewed verified by ORBi |
 | Seleznik, G. M., Reding, T., Peter, L., Gupta, A., Steiner, S. G., Sonda, S., Verbeke, C. S., Dejardin, E., Khatkov, I., Segerer, S., Heikenwalder, M., & Graf, R. (2018). Development of autoimmune pancreatitis is independent of CDKN1A/p21-mediated pancreatic inflammation. Gut. doi:10.1136/gutjnl-2016-313458 Peer Reviewed verified by ORBi |
 | Boege, Y., Malehmir, M., Healy, M. E., Bettermann, K., Lorentzen, A., Vucur, M., Ahuja, A. K., Bohm, F., Mertens, J. C., Shimizu, Y., Frick, L., Remouchamps, C., Mutreja, K., Kahne, T., Sundaravinayagam, D., Wolf, M. J., Rehrauer, H., Koppe, C., Speicher, T., ... Weber, A. (2017). A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development. Cancer Cell, 32 (3), 342-359.e10. doi:10.1016/j.ccell.2017.08.010 Peer Reviewed verified by ORBi |
 | Fernandes, M. T., Dejardin, E., & Santos, N. R. D. (2016). Context-dependent roles for lymphotoxin-beta receptor signaling in cancer development. Biochimica et Biophysica Acta. doi:10.1016/j.bbcan.2016.02.005 Peer Reviewed verified by ORBi |
 | Boutaffala, L., Bertrand, M. J. M., Remouchamps, C., Seleznik, G., Reisinger, F., Janas, M., Benezech, C., Fernandes, M. T., Marchetti, S., Mair, F., Ganeff, C., Hupalowska, A., Ricci, J.-E., Becher, B., Piette, J., Knolle, P., Caamano, J., Vandenabeele, P., Heikenwalder, M., & Dejardin, E. (December 2015). NIK promotes tissue destruction independently of the alternative NF-kappaB pathway through TNFR1/RIP1-induced apoptosis. Cell Death and Differentiation, 10.1038/cdd.2015.69. doi:10.1038/cdd.2015.69 Peer Reviewed verified by ORBi |
 | Fernandes, M. T., Ghezzo, M. N., Silveira, A. B., Kalathur, R. K., Povoa, V., Ribeiro, A. R., Brandalise, S. R., Dejardin, E., Alves, N. L., Ghysdael, J., Barata, J. T., Yunes, J. A., & Dos Santos, N. R. (2015). Lymphotoxin-beta receptor in microenvironmental cells promotes the development of T-cell acute lymphoblastic leukaemia with cortical/mature immunophenotype. British Journal of Haematology. doi:10.1111/bjh.13760 Peer Reviewed verified by ORBi |
 | Singh, P.* , Dejager, L.* , Amand, M.* , Theatre, E., Vandereyken, M., Zurashvili, T., Singh, M., Mack, M., Timmermans, S., Musumeci, L., Dejardin, E., Mustelin, T., Van Ginderachter, J. A., Moutschen, M., Oury, C., Libert, C., & Rahmouni, S. (15 May 2015). DUSP3 genetic deletion confers M2-like−macrophage-dependent tolerance to septic shock. Journal of Immunology, 194 (10), 4951-62. doi:10.4049/jimmunol.1402431 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | Remouchamps, C., & Dejardin, E. (2015). Methods to Assess the Activation of the Alternative (Noncanonical) NF-kappaB Pathway by Non-death TNF Receptors. In NF-kappa B: Methods and Protocols (pp. 103-19). United States: Michael J May (ed.). doi:10.1007/978-1-4939-2422-6_7 Peer reviewed |
 | Chau, T.-L., Göktuna, S., Rammal, A., Casanova Bustos, T. R., Duong, H. Q., GATOT, J.-S., Close, P., Dejardin, E., Desmecht, D., Shostak, K., & Chariot, A. (2015). A role for APPL1 in tlr3/4-dependent TBK1 and IKKε activation in macrophages. Journal of Immunology. doi:10.4049/jimmunol.1401614 Peer Reviewed verified by ORBi |
 | Dondelinger, Y., Jouan-Lanhouet, S., Divert, T., Théâtre, E., Bertin, J., Gough, P. J., Giansanti, P., Heck, A. J. R., Dejardin, E., Vandenabeele, P., & Bertrand, M. J. M. (2015). NF-kappaB-Independent Role of IKKalpha/IKKbeta in Preventing RIPK1 Kinase-Dependent Apoptotic and Necroptotic Cell Death during TNF Signaling. Molecular Cell. doi:10.1016/j.molcel.2015.07.032 Peer Reviewed verified by ORBi |
Dejardin, E. (05 November 2014). Discovery of new E3 ligases for the alternative NF-κB pathway [Paper presentation]. First Proteostasis meeting of the COST Action BM1307, Valencia, Spain. |
 | Lucifora, J., Xia, Y., Reisinger, F., Zhang, K., Stadler, D., Cheng, X., Sprinzl, M. F., Koppensteiner, H., Makowska, Z., Volz, T., Remouchamps, C., Chou, W.-M., Thasler, W. E., Huser, N., Durantel, D., Liang, T. J., Munk, C., Heim, M. H., Browning, J. L., ... Protzer, U. (14 March 2014). Specific and Nonhepatotoxic Degradation of Nuclear Hepatitis B Virus cccDNA. Science, 343. doi:10.1126/science.1243462 Peer Reviewed verified by ORBi |
 | Gray, C. M., Remouchamps, C., McCorkell, K. A., Solt, L. A., Dejardin, E., Orange, J. S., & May, M. J. (2014). Noncanonical NF-kappaB Signaling Is Limited by Classical NF-kappaB Activity. Science Signaling, 7 (311), 13. doi:10.1126/scisignal.2004557 Peer Reviewed verified by ORBi |
Dejardin, E. (08 November 2013). Pro-death function of the NIK kinase in TNF-α-induced thymic involution [Paper presentation]. BIS Annual Meeting, Liège, Belgium. |
 | Dondelinger, Y., Aguileta, M., Goosens, V., Dubuisson, C., Grootjans, S., Dejardin, E., Vandenabeele, P., & Bertrand, M. (20 October 2013). RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition. Cell Death and Differentiation, 10, 1381-92. doi:10.1038/cdd.2013.94 Peer Reviewed verified by ORBi |
Dejardin, E. (01 October 2012). Discovery of new E3 ligases for the control of the alternative NF-kB pathway [Paper presentation]. NF-kB subunit workshop, Rauischholzhausen, Germany. |
 | Ganeff, C., Remouchamps, C., Boutaffala, L., Benezech, C., Galopin, G., Vandepaer, S., Bouillenne, F., Ormenese, S., Chariot, A., Schneider, P., Caamano, J., Piette, J., & Dejardin, E. (30 November 2011). Induction of the Alternative NF-{kappa}B Pathway by Lymphotoxin {alpha}{beta} (LT{alpha}{beta}) Relies on Internalization of LT{beta} Receptor. Molecular and Cellular Biology, 21, 4319-4334. doi:10.1128/MCB.05033-11 Peer Reviewed verified by ORBi |
Boutaffala, L., Bertrand, M., Remouchamps, C., Ganeff, C., Marchetti, S., Vandenabeele, P., Piette, J., Caamano, J., Heikenwalder, M., & Dejardin, E. (2011). The hidden function of NIK (NF-κB-Inducing Kinase) in cell death [Paper presentation]. 13th International TNF Conference, Awaji island, Japan. |
 | Remouchamps, C., Boutaffala, L., Ganeff, C., & Dejardin, E. (2011). Biology and Signal Transduction pathways of the Lymphotoxin-αβ/LTβR system. Cytokine and Growth Factor Reviews, 22, 301-310. doi:10.1016/j.cytogfr.2011.11.007 Peer Reviewed verified by ORBi |
Boutafalla, L., Bertrand, M., Remouchamps, C., Ganeff, C., Marchetti, S., Ricci, J.-E., Piette, J., Caamano, J., Vandenabeele, P., Heihenwalder, M., & Dejardin, E. (2010). TNFR-induced activation of MAP3K14/NIK enhances TNFR1-induced cell death [Paper presentation]. 18th Euroconference on Apoptosis (ECDO), Gent, Belgium. |
 | Mortier, J., Frederick, R., Ganeff, C., Remouchamps, C., Talaga, P., Pochet, L., Wouters, J., Piette, J., Dejardin, E., & Masereel, B. (2010). Pyrazolo[4,3-c]isoquinolines as potential inhibitors of NF-kappaB activation. Biochemical Pharmacology, 79 (10), 1462-72. doi:10.1016/j.bcp.2010.01.007 Peer Reviewed verified by ORBi |
Ganeff, C., Galopin, G., Remouchamps, C., Benezech, C., Boutaffala, L., de trez, C., Bouillenne, F., Ormenese, S., CHARIOT, A., Norris, P., Ware, C., Schneider, P., Caamano, J., Piette, J., & Dejardin, E. (January 2010). TNFL–Induced p100 processing (TIPP) relies on the internalization of the cognate TNFR [Paper presentation]. Inflammation 2010, Luxembourg, Luxembourg. |
Dejardin, E. (2010). Interplay between non-death and death TNFR in inflammation [Paper presentation]. 6th CCN meeting, Newcastle, Ireland. |
Dejardin, E., Droin, N., Delhase, M., Haas, E., Cao, Y., Makris, C., Li, Z.-W., Karin, M., Ware, C., & Green, D. (30 October 2009). The lymphotoxin-β receptor induces different patterns of gene expression via two NF-κB pathways [Paper presentation]. TNF Superfamily Conference 2002, San Diego, United States. |
 | Robert, I., Aussems, M., Keutgens, A., Zhang-Shao, X., Hennuy, B., Viatour, P., Vanstraelen, G., Merville, M.-P., Chapelle, J.-P., de Leval, L., LAMBERT, F., Dejardin, E., Gothot, A., & Chariot, A. (02 April 2009). Matrix Metalloproteinase-9 gene induction by a truncated oncogenic NF-κB2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes. Oncogene, 28 (13), 1626-1638. doi:10.1038/onc.2009.6 Peer Reviewed verified by ORBi |
 | Goval, J.-J., Thielen, C., Bourguignon, C., Greimers, R., Dejardin, E., Choi, Y. S., Boniver, J., & de Leval, L. (August 2008). The prevention of spontaneous apoptosis of follicular lymphoma B cells by a follicular dendritic cell line: involvement of caspase-3, caspase-8 and c-FLIP. Haematologica, 93 (8), 1169-77. doi:10.3324/haematol.12127 Peer Reviewed verified by ORBi |
 | Cornez, I., Creppe, C., Gillard, M., Hennuy, B., Chapelle, J.-P., Dejardin, E., Merville, M.-P., Close, P., & Chariot, A. (June 2008). Deregulated expression of pro-survival and pro-apoptotic p53-dependent genes upon Elongator deficiency in colon cancer cells. Biochemical Pharmacology, 75, 2122-2134. doi:10.1016/j.bcp.2008.03.006 Peer Reviewed verified by ORBi |
Gioia, R., GATOT, J.-S., Chau, T.-L., Warnier, M., Chapelle, J.-P., Piette, J., Dejardin, E., & Chariot, A. (December 2007). Insight into the TBK1/IKK-dependent signalling pathways required in innate immunity through identification of the TANK/I-TRAF interactome [Poster presentation]. Journée Télévie, ULB GOsselies, Belgium. |
 | GATOT, J.-S., Gioia, R., Chau, T.-L., Patrascu, F. A., Warnier, M., Close, P., Chapelle, J.-P., Muraille, E., Brown, K., Siebenlist, U., Piette, J., Dejardin, E., & Chariot, A. (26 October 2007). Lipopolysaccharide-mediated interferon regulatory factor activation involves TBK1-IKK epsilon-dependent lys(63)-linked polyubiquitination and phosphorylation of TANK/I-TRAF. Journal of Biological Chemistry, 282 (43), 31131-31146. doi:10.1074/jbc.M701690200 Peer Reviewed verified by ORBi |
 | Lambert, C., Oury, C., Dejardin, E., Chariot, A., Piette, J., Malaise, M., Merville, M.-P., & Franchimont, N. (September 2007). Further insights in the mechanisms of interleukin-1beta stimulation of osteoprotegerin in osteoblast-like cells. Journal of Bone and Mineral Research, 22 (9), 1350-1361. doi:10.1359/jbmr.070508 Peer Reviewed verified by ORBi |
 | Gloire, G., Horion, J., El Mjiyad, N., Bex, F., Chariot, A., Dejardin, E., & Piette, J. (20 July 2007). Promoter-dependent effect of IKK alpha on NF-kappa B/p65 DNA binding. Journal of Biological Chemistry, 282 (29), 21308-21318. doi:10.1074/jbc.M610728200 Peer Reviewed verified by ORBi |
GATOT, J.-S., Gioia, R., Chau, T.-L., Warnier, M., Chapelle, J.-P., Merville, M.-P., Brown, K., Siebenlist, U., Muraille, E., Dejardin, E., Piette, J., & Chariot, A. (March 2007). Polyubiquitination of the scaffold protein tank/I-traf: implications for the TLR-mediated signalling pathways [Poster presentation]. Colloque "Chromatin Dynamics and Epigenetics" Société belge de biologie cellulaire et du développement, Liège, Belgium. |
 | El Mjiyad, N., Bontems, S., Gloire, G., Horion, J., Vandevenne, P., Dejardin, E., Piette, J., & Sadzot-Delvaux, C. (2007). Varicella-zoster virus modulates NF-kappaB recruitment on selected cellular promoters. Journal of Virology, 81 (23), 13092-104. doi:10.1128/JVI.01378-07 Peer Reviewed verified by ORBi |
 | Dejardin, E. (30 October 2006). The alternative NF-kappa B pathway from biochemistry to biology: Pitfalls and promises for future drug development [letter to the editor]. Biochemical Pharmacology, 72 (9), 1161-1179. doi:10.1016/j.bcp.2006.08.007 Peer Reviewed verified by ORBi |
| Gloire, G., Dejardin, E., & Piette, J. (30 October 2006). Extending the nuclear roles of I kappa B kinase subunits. Biochemical Pharmacology, 72 (9), 1081-1089. doi:10.1016/j.bcp.2006.06.017 Peer Reviewed verified by ORBi |
 | Maurer, U., Charvet, C., Wagman, A., Dejardin, E., & Green, D. (17 March 2006). Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1. Molecular Cell, 21 (6), 749-760. doi:10.1016/j.molcel.2006.02.009 Peer Reviewed verified by ORBi |
 | Viatour, P., Dejardin, E., Warnier, M., Lair, F., Claudio, E., Bureau, F., Marine, J. C., Merville, M.-P., Maurer, U., Green, D., Piette, J., Siebenlist, U., Bours, V., & Chariot, A. (08 October 2004). GSK3-Mediated BCL-3 phosphorylation modulates its degradation and its oncogenicity. Molecular Cell, 16 (1), 35-45. doi:10.1016/j.molcel.2004.09.004 Peer Reviewed verified by ORBi |
 | Droin, N., Pinkoski, M., Dejardin, E., & Green, D. (November 2003). Egr family members regulate nonlymphoid expression of Fas ligand, TRAIL, and tumor necrosis factor during immune responses. Molecular and Cellular Biology, 23 (21), 7638-7647. doi:10.1128/MCB.23.21.7638-7647.2003 Peer Reviewed verified by ORBi |
 | Derudder, E., Dejardin, E., Pritchard, L. L., Green, D. R., Korner, M., & Baud, V. (2003). RelB/p50 dimers are differentially regulated by tumor necrosis factor-alpha and lymphotoxin-beta receptor activation: critical roles for p100. Journal of Biological Chemistry, 278 (26), 23278-84. doi:10.1074/jbc.M300106200 Peer Reviewed verified by ORBi |
| Dejardin, E., Droin, N., Delhase, M., Haas, E., Cao, Y., Makris, C., Li, Z.-W., Karin, M., Ware, C., & Green, D. (October 2002). The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways. Immunity, 17, 525-535. doi:10.1016/S1074-7613(02)00423-5 Peer Reviewed verified by ORBi |
Dejardin, E., Droin, N., Delhase, M., Hass, E., Cao, Y., Makris, C., Li, Z.-W., Karin, M., Ware, C., & Green, D. (2002). The lymphotoxin-β receptor induces different patterns of gene expression via two NF-κB pathways [Paper presentation]. TNF Superfamily Conference 2002, San Diego, United States. |
Dejardin, E., Haas, E., Ware, C., & Green, D. (09 November 2001). IKKα and IKKβ have different roles in LTβR-mediated NF-κB activation [Paper presentation]. e Cytokine Odyssey 2001, Maui, United States - Hawaii. |
Bentires-Alj, M., Dejardin, E., Viatour, P., Van Lint, C., Froesch, B., Reed, J. C., Merville, M.-P., & Bours, V. (11 May 2001). Inhibition of the Nf-Kappa B Transcription Factor Increases Bax Expression in Cancer Cell Lines. Oncogene, 20 (22), 2805-13. doi:10.1038/sj.onc.1204343 Peer Reviewed verified by ORBi |
Dejardin, E., Deregowski, V., Chapelier, M., Jacobs, N., Gielen, J., Merville, M.-P., & Bours, V. (22 April 1999). Regulation of Nf-Kappab Activity by I Kappab-Related Proteins in Adenocarcinoma Cells. Oncogene, 18 (16), 2567-77. doi:10.1038/sj.onc.1202599 Peer Reviewed verified by ORBi |
 | Dejardin, E., Deregowski, V., GREIMERS, R., Cai, Z., Chouaib, S., Merville, M.-P., & BOURS, V. (1998). Regulation of major histocompatibility complex class I expression by NF-kB-related proteins in breast cancer cells. Oncogene. doi:10.1038/sj.onc.1201879 Peer Reviewed verified by ORBi |
Bonizzi, G., Dejardin, E., Piret, B., Piette, J., Merville, M.-P., & Bours, V. (15 December 1996). Interleukin-1 Beta Induces Nuclear Factor Kappa B in Epithelial Cells Independently of the Production of Reactive Oxygen Intermediates. European Journal of Biochemistry, 242 (3), 544-9. doi:10.1111/j.1432-1033.1996.0544r.x Peer Reviewed verified by ORBi |
Dejardin, E., Bonizzi, G., Bellahcene, A., Castronovo, V., Merville, M.-P., & Bours, V. (02 November 1995). Highly-Expressed P100/P52 (Nfkb2) Sequesters Other Nf-Kappa B-Related Proteins in the Cytoplasm of Human Breast Cancer Cells. Oncogene, 11 (9), 1835-41. Peer Reviewed verified by ORBi |
Bours, V., Dejardin, E., Goujon-Letawe, F., Merville, M.-P., & Castronovo, V. (13 January 1994). The Nf-Kappa B Transcription Factor and Cancer: High Expression of Nf-Kappa B- and I Kappa B-Related Proteins in Tumor Cell Lines. Biochemical Pharmacology, 47 (1), 145-9. doi:10.1016/0006-2952(94)90448-0 Peer Reviewed verified by ORBi |
Bours, V., Azarenko, V., Dejardin, E., & Siebenlist, U. (1994). Human RelB (I-Rel) functions as a kappa B site-dependent transactivating member of the family of Rel-related proteins. Oncogene, 9 (6), 1699-702. Peer Reviewed verified by ORBi |
