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Grobet Luc

Département de morphologie et pathologie (DMP) > Embryologie

FARAH: Santé publique vétérinaire

See author's contact details
Main Referenced Co-authors
Ectors, Fabien  (26)
Antoine, Nadine  (22)
Piret, Joëlle  (17)
Connan, Delphine  (11)
Georges, Michel  (10)
Main Referenced Keywords
cryopreservation (4); Chicken primordial germ cells (3); myostatin (3); Travail de fin d'études (3); Vitrification (3);
Main Referenced Unit & Research Centers
FARAH - Fundamental and Applied Research for Animals and Health - ULiège [BE] (9)
Giga-Development and Stem Cells - ULiège [BE] (7)
ULg - Université de Liège (4)
ULiège - Université de Liège (2)
FARAH (Fundamental and Applied Research in Animal Health) (1)
Main Referenced Disciplines
Anatomy (cytology, histology, embryology...) & physiology (22)
Veterinary medicine & animal health (21)
Biotechnology (15)
Genetics & genetic processes (8)
Laboratory medicine & medical technology (3)

Publications (total 55)

The most downloaded
2488 downloads
Grobet, L. (21 March 2018). Le travail de Fin d'études à la Faculté de Médecine Vétérinaire: What's new since 2014? [Paper presentation]. Formation IFRES: Accompagner et évaluer des mémoires et TFEs, Liège, Belgium. https://hdl.handle.net/2268/224771

The most cited

389 citations (Scopus®)

Grobet, L., Poncelet, D., Royo, L. J., Brouwers, B., Pirottin, D., Geudvert, C., Menissier, F., Zanotti, M., Dunner, S., & Georges, M. (1998). Molecular Definition of an Allelic Series of Mutations Disrupting the Myostatin Function and Causing Double-Muscling in Cattle. Mammalian Genome, 9 (3), 210-3. doi:10.1007/s003359900727 https://hdl.handle.net/2268/34391

Ectors, F., Vanderzwalmen, P., Dupuis, N., Connan, D., & Grobet, L. (2018). ONE-STEP VITRIFICATION OF MURINE EMBRYOS CHALLENGES CURRENT PARADIGMS OF CRYOBIOLOGY. In D. M. Rawson (Ed.), Cryobiology. Amsterdam, Netherlands: Elsevier.
Peer reviewed

Connan, D., Ectors, F., Vanderzwalmen, P., & Grobet, L. (05 July 2018). Méthode de vitrification en une étape.

Ectors, F., Vanderzwalmen, P., dupuis, N., Connan, D., & Grobet, L. (13 June 2018). La vitrification en une seule étape d’embryons murins définit de nouveaux standards de cryopréservation [Poster presentation]. AFSTAL (Association Française des Sciences et Techniques de l’Animal de Laboratoire) symposium, Reims, France.

Grobet, L. (07 May 2018). VitriCell: The cool way from academic research to company foundation [Paper presentation]. Présentation de partenariats concrétisés et potentiels entre la Faculté de Médecine Vétérinaire et Meusinvest, Liège, Belgium.

Bakker, J., Balthazart, J., Baron, F., Beguin, Y., Bettendorff, L., Blanpain, C., Bureau, F., Caers, J., Cani, P., Cataldo, D., Cornil, C., Clercx, C., Cloots, R., Colige, A., Daube, G., De Backer, O., de Kerchove d'Exaerde, A., Desmecht, D., Desmet, C., ... Wittamer, V. (2018). La souris, le patient, et le faux expert. Décryptage d'une mystification. Le Vif. L'Express.

Ectors, F., Vanderzwalmen, P., Dupuis, N., Connan, D., & Grobet, L. (26 April 2018). One-step vitrification of murine embryos redefines cryopreservation standards [Poster presentation]. BCLAS (Belgian Council for Laboratory Animal Science) symposium 2018, Liège, Belgium.

Grobet, L. (21 March 2018). Le travail de Fin d'études à la Faculté de Médecine Vétérinaire: What's new since 2014? [Paper presentation]. Formation IFRES: Accompagner et évaluer des mémoires et TFEs, Liège, Belgium.

Connan, D., Ectors, F., & Grobet, L. (06 March 2018). VitriCell: The cool way from academic research to company foundation [Poster presentation]. 20 ans de First Spin-off en wallonie, Namur, Belgium.

Tonus, C.* , Connan, D.* , Waroux, O.* , Vandenhove, B., Wayet, J., Gillet, L., Desmecht, D., Antoine, N., Ectors, F., & Grobet, L. (15 January 2017). Cryopreservation of chicken primordial germ cells by vitrification and slow-freezing: a comparative study. Theriogenology, 88, 197-206. doi:10.1016/j.theriogenology.2016.09.022
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Connan, D., Ectors, F., Vanderzwalmen, P., Antoine, N., & Grobet, L. (08 December 2016). VitriCell: the safest key for cryopreserving your valuable cells [Poster presentation]. 6th edition science for business Biowin Day 2016, Louvain-La-Neuve, Belgium.

Connan, D., Ectors, F. (Other coll.), Antoine, N. (Other coll.), Vanderzwalmen, P. (Other coll.), & Grobet, L. (Other coll.). (September 2016). VITRICELL: new efficient method for cryopreserving cells by vitrification [Paper presentation]. 2016 Bioregate European Regenerative Medicine Forum, Nantes, France.

Tonus, C., Cloquette, K., Ectors, F., Piret, J., Gillet, L., Antoine, N., Desmecht, D., Vanderplasschen, A., Waroux, O.* , & Grobet, L.*. (2016). Long term-cultured and cryopreserved primordial germ cells from various chicken breeds retain high proliferative potential and gonadal colonisation competency. Reproduction, Fertility and Development, 28 (5), 628-639. doi:10.1071/RD14194
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Tonus, C., Garcia Gil, F. J., Cloquette, K., Connan, D., Gillet, L., Piret, J., Ectors, F., Antoine, N., Desmecht, D., Vanderplasschen, A., Waroux, O., & Grobet, L. (16 October 2015). Long term culture, cryopreservation and genetic modification of chicken primordial germ cells [Poster presentation]. FARAH Day 2015, Liège, Belgium.

Connan, D., Ectors, F., Piret, J., Antoine, N., & Grobet, L. (27 July 2015). Efficient automatable and aseptic vitrification of human pluripotent stem cells using bio-safe and chemically defined media [Paper presentation]. CRYO2015: Annual meeting of the Society for Cryobiology, Ostrava, Czechia.

Connan, D., Ectors, F., Piret, J., Antoine, N., & Grobet, L. (26 November 2014). Efficient aseptic and automatable vitrification of human Embryonic Stem Cells using bio-safe & chemically defined media [Poster presentation]. 5ème édition du Science For Business-BioWin Day, Louvain-La-Neuve, Belgium.

Grobet, L. (March 2014). Le travail de fin d'études à la FMV: Définition, objectifs, évaluation et modalités [Paper presentation]. Formation IFRES: Accompagner et évaluer des mémoires et TFEs, Liège, Belgium.

Connan, D., Ectors, F., Piret, J., Antoine, N., & Grobet, L. (27 January 2014). Efficient aseptic and automatable vitrification of human Embryonic Stem Cells using bio-safe & chemically defined media [Poster presentation]. GIGA DAY 2014.

Waroux, O., Tonus, C., & Grobet, L. (26 October 2013). Long term culture and characterization of avian primordial germ cells [Paper presentation]. Avian Germplasm Rorum 2013, Seoul, South Korea.

Tonus, C., Cloquette, K., Ectors, F., Piret, J., Antoine, N., Waroux, O., & Grobet, L. (October 2013). Long term culture and characterization of chicken primordial germ cells [Poster presentation]. Avian Germplasm Forum, Seoul, South Korea.

Toppets, V., Piret, J., Gabriel, A., Grobet, L., Simoens, P., Van Den Broeck, W., Cornillie, P., & Antoine, N. (2013). Three-dimensional reconstruction of the pharyngeal tonsil innervation pattern in sheep. Journal of Neuroimmunology, (262), 79-84. doi:10.1016/j.jneuroim.2013.07.004
Peer Reviewed verified by ORBi

Vanderzwalmen, P., Ectors, F., Grobet, L., Lejeune, B., Puissant, F., Stecher, A., Uranga, I., Vanderzwalmen, S., Wirtleitner, B., Zintz, M., & Zech, N. (2013). Chapter 13: Adaptation of a Universal Procedure for Cryopreservation of Different Developmental Stages: Is it Conceivable? In A. C. Varghese, P. Sjöblom, ... K. Jayaprakasan (Eds.), A practical guide to setting up an IVF lab, embryo culture systems and running the unit (1st edition, pp. 118-131). New Delhi, India: Jaypee.

Connan, D., Ectors, F., Piret, J., Antoine, N., & Grobet, L. (19 June 2013). Efficient aseptic and automatable vitrification of human embryonic stem cells using bio-safe & chemically defined media [Poster presentation]. Biomedica.

Connan, D., Ectors, F., Piret, J., Antoine, N., & Grobet, L. (18 April 2013). Efficient aseptic and automatable vitrification of human Embryonic Stem Cells using bio-safe & chemically defined media [Poster presentation]. Bioliège.

Connan, D., Ectors, F., Grobet, L., Piret, J. (Other coll.), & Antoine, N. (Other coll.). (23 March 2013). Efficient aseptic and automatable vitrification of human Embryonic Stem Cells using bio-safe & chemically defined media [Paper presentation]. The 3rd international congress on controversies in Cryopreservation of Stem Cells, Reproductive Cells, Tissue & Organs (CRYO), Berlin, Germany.

Connan, D., Vanderzwalmen, P., Grobet, L., Ectors, F., Wirtleiner, B. (Other coll.), Remy, B. (Other coll.), Vanderzwalmen, S. (Other coll.), & Zech, N. (Other coll.). (22 March 2013). Lower intracellular concentration of cryoprotectants in mouse zygotes after vitrification than after slow freezing [Poster presentation]. The 3rd international congress on controversies in Cryopreservation of Stem Cells, Reproductive Cells, Tissue & Organs (CRYO), Berlin, Germany.

Tonus, C., Waroux, O., & Grobet, L. (12 March 2013). A method allowing long term culture and expansion of chicken primordial germ cells [Paper presentation]. Avian Germplasm meeting, Lyon, France.

Grobet, L. (March 2013). Le travail de Fin d'études à la Faculté de Médecine Vétérinaire: situation en 2012-2013 [Paper presentation]. Formation IFRES: Accompagner et évaluer des mémoires et TFEs, Liège, Belgium.

Vanderzwalmen, P., Connan, D., Grobet, L., Wirleitner, B., Remy, B., Vanderzwalmen, S., Zech, N., & Ectors, F. (2013). Lower intracellular concentration of cryoprotectants after vitrification than after slow freezing despite exposure to higher concentration of cryoprotectant solutions. Human Reproduction. doi:10.1093/humrep/det107
Peer Reviewed verified by ORBi

Tonus, C., Waroux, O., Cloquette, K., Ectors, F., Piret, J., Antoine, N., & Grobet, L. (November 2012). Long term culture and characterization of chicken primordial germ cells [Poster presentation]. 7th International Chick meeting - Chick7: Avian Model Sytems, Nagoya, Japan.

Connan, D., Ectors, F., Grobet, L., Bavington, C. (Other coll.), & Antoine, N. (Other coll.). (22 October 2012). OPTIMIZATION OF HUMAN ES CELLS (hESCs) CRYOPRESERVATION [Poster presentation]. BEST Stem Cells Symposium, Edinburgh, United Kingdom.

Ectors, F., Connan, D., & Grobet, L. (22 October 2012). Aseptic and automatable vitrification of human embryonic stem cells using defined media [Paper presentation]. BEST stem Cells symposium, Edinburgh, United Kingdom.

Toppets, V., Piret, J., Grobet, L., Gabriel, A., Simoens, P., Van den Broeck, W., Cornillie, P., & Antoine, N. (19 October 2012). The three-dimensional reconstruction of the innervation pattern in the lymphoid compartment of the ovine pharyngeal tonsil highlighted a possible way of neuro-invasion by the scrapie agent [Paper presentation]. 2nd Scientific Meeting of the Faculty of Veterinary Medicine.

Toppets, V., Piret, J., Gabriel, A., Grobet, L., Simoens, P., Van Den Broeck, W., Cornillie, P., & Antoine, N. (19 October 2012). Three-dimensional reconstruction of the pharyngeal tonsil innervation pattern in sheep [Poster presentation]. 2nd Scientific Meeting of the Facultu of Veterinary Medicine.

Toppets, V., Piret, J., Kirschvink, N., Lantier, F., Lantier, I., Berthon, P., Daube, G., Massart, L., Grobet, L., & Antoine, N. (17 March 2012). Neuroimmune connections in ovine pharyngeal tonsil: potential site for prion neuroinvasion. Cell and Tissue Research, 348, 167-76. doi:10.1007/s00441-012-1376-x
Peer Reviewed verified by ORBi

Toppets, V., Defaweux, V., Piret, J., Kirschvink, N., Grobet, L., & Antoine, N. (31 January 2011). Features of follicular dendritic cells in ovine pharyngeal tonsil: An in vivo and in vitro study in the context of scrapie pathogenesis. Veterinary Immunology and Immunopathology, 141, 26-32. doi:10.1016/j.vetimm.2011.01.014
Peer Reviewed verified by ORBi

Vanderzwalmen, P., Ectors, F., Papras, Y., Zech, M., Jareno, D., Lejeune, B., Vanderzwalmen, S., Wirleitner, B., Zech, N., & Grobet, L. (2011). Cryopréservation d’ovocytes et d’embryons par congélation ou vitrification dans le cadre de l’assistance médicale à la procréation. In C. Poncelet & C. Sifer (Eds.), Physiologie, pathologie et thérapie de la reproduction chez l’humain (pp. 567-586). France: Springer-Verlag.
Peer reviewed

Toppets, V., Piret, J., Defaweux, V., Dorban, G., Grobet, L., & Antoine, N. (October 2009). Distribution and frequency of nerves fibres in palatine and pharyngeal tonsils [Poster presentation]. Conférence Prion2009, Thessalonique, Greece.

Vanderzwalmen, P., Ectors, F., Grobet, L., Prapas, Y., Panagiotidis, Y., Vanderzwalmen, S., Stecher, A., Frias, P., Liebermann, J., & Zech, N. H. (2009). Aseptic vitrification of blastocysts from infertile patients, egg donors and after IVM. Reproductive Biomedicine Online, 19 (5), 700-707. doi:10.1016/j.rbmo.2009.09.011
Peer Reviewed verified by ORBi

Toppets, V., Piret, J., Defaweux, V., Dorban,G, Jacqmot, O., Grobet, L., & Antoine, N. (October 2008). Neuroimmune contact between peripheral nervous system and follicular dendritic cells in ovine lymph organs [Poster presentation]. Prion 2008, Madrid, Spain.

Grobet, L., Pirottin, D., & Georges, M. (15 November 2007). Genetic engineering in the mouse: from functional genomics to zootechnical applications [Paper presentation]. BCLAS (Belgian Council for Laboratory Animal Science) symposium 2007, Geel, Belgium.

Grobet, L. (15 November 2007). Genetic engineering in the mouse: from functional genomics to zootechnical applications [Paper presentation]. BCLAS (Belgian Council for Laboratory Animal Science) symposium 2007.

Gilson, H., Schakman, O., Combaret, L., Lause, P., Grobet, L., Attaix, D., Ketelslegers, J. M., & Thissen, J. P. (January 2007). Myostatin gene deletion prevents glucocorticoid-induced muscle atrophy. Endocrinology, 148 (1), 452-460. doi:10.1210/en.2006-0539
Peer Reviewed verified by ORBi

Toppets, V., Piret,J, Minne , M, Grobet, L., & Antoine, N. (October 2006). Are CNA42 and FDC-B1 directed against ovine follicular dendritic cells? [Poster presentation]. Prion 2006, Torino, Italy.

Pirottin, D., Grobet, L., Adamantidis, A., Farnir, F., Herens, C., Daa Schroder, H., & Georges, M. (2005). Transgenic engineering of male-specific muscular hypertrophy. Proceedings of the National Academy of Sciences of the United States of America, 102 (18), 6413-8. doi:10.1073/pnas.0502426102
Peer Reviewed verified by ORBi

Grobet, L., Pirottin, D., Farnir, F., Poncelet, D., Royo, L. J., Brouwers, B., Christians, E., Desmecht, D., Coignoul, F., Kahn, R., & Georges, M. (2003). Modulating skeletal muscle mass by postnatal, muscle-specific inactivation of the myostatin gene. Genesis, 35 (4), 227-38. doi:10.1002/gene.10188
Peer Reviewed verified by ORBi

Grobet, L. (21 October 2000). A successful positional cloning in cattle: characterization of the myostatin gene whose loss of function alleles cause hypermuscularity [Paper presentation]. Session ordinaire de l'Académie Royale de Médecine de Belgique, Bruxelles, Belgium.

Grobet, L., & Georges, M. (15 August 2000). Double-muscling in mammals" Gene réf. Myostatin (MSTN).

Grobet, L., Fernandez, C., Pirottin, D., Poncelet, D., Brouwers, B., & Georges, M. (2000). Engineering of the murine myostatin gene in es cells in order to generate cre-loxp-based conditional and inducible mstn on to off and mstn off to on mice strains. Cloning, 2 (3), 148.
Peer Reviewed verified by ORBi

Karim, L., Coppieters, W., Grobet, L., Valentini, A., & Georges, M. (2000). Convenient Genotyping of Six Myostatin Mutations Causing Double-Muscling in Cattle Using a Multiplex Oligonucleotide Ligation Assay. Animal Genetics, 31 (6), 396-9. doi:10.1046/j.1365-2052.2000.00684.x
Peer Reviewed verified by ORBi

Pirottin, D., Poncelet, D., Grobet, L., Royo, L. J., Brouwers, B., Masabanda, J., Takeda, H., Fries, R., Sugimoto, Y., Womack, J. E., Dunner, S., & Georges, M. (1999). High-Resolution, Human-Bovine Comparative Mapping Based on a Closed Yac Contig Spanning the Bovine Mh Locus. Mammalian Genome, 10 (3), 289-93. doi:10.1007/s003359900988
Peer Reviewed verified by ORBi

Grobet, L., Georges, M., & Poncelet, D. (01 January 1999). Mutation du Gene de la Myostatine à l'origine de l'hypertrophie muscumaire chez les mammifères.

Marcq, F., El Barkouki, S., Elsen, J.-M., Grobet, L., Royo, L., Leroy, P., & Georges, M. (1998). Investigating the role of myostatin in the determinism of double muscling characterizing Belgian Texel sheep [Paper presentation]. Proc XXVIth Int. Conf. Anim. Genet., Auckland, New Zealand (Animala Genetics, 29, suppl. 1 abstr.,52).
Peer reviewed

Grobet, L., Poncelet, D., Royo, L. J., Brouwers, B., Pirottin, D., Geudvert, C., Menissier, F., Zanotti, M., Dunner, S., & Georges, M. (1998). Molecular Definition of an Allelic Series of Mutations Disrupting the Myostatin Function and Causing Double-Muscling in Cattle. Mammalian Genome, 9 (3), 210-3. doi:10.1007/s003359900727
Peer Reviewed verified by ORBi

Grobet, L., Schwers, A., Charlier, C., Marcq, F., Ectors, F., Touati, K., & Hanset. (1992). Le sexage d'embryons bovins par la technique de l'amplification en chaîne par la polymérase (acp) d'une séquence Y-spécifique bovine. Annales de Médecine Vétérinaire, 136, 119-124.

Grobet, L., Gabriel, A., Istasse, L., & Lekeux, P. (1989). L'hormone de croissance en production de viande. Annales de Médecine Vétérinaire, 133, 377-390.
Peer Reviewed verified by ORBi

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