Publications and communications of Claire Josse

Poulet, C.* , Debit, A.* , Josse, C., Jerusalem, G., Azencott, C.-A., Bours, V., & Van Steen, K. (2023). Assessing Random Forest self-reproducibility for optimal short biomarker signature discovery. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/303314. doi:10.1101/2023.03.29.534695

BOEMER, F., JOSSE, C., LUIS, G., Di Valentin, E., Thiry, J., CELLO, C., CABERG, J.-H., DADOUMONT, C., HARVENGT, J., Lumaka, A., BOURS, V., & DEBRAY, F.-G. (18 February 2022). Novel Loss of Function Variant in BCKDK Causes a Treatable Developmental and Epileptic Encephalopathy. International Journal of Molecular Sciences, 23 (4), 2253. doi:10.3390/ijms23042253

Bhardwaj, A., Josse, C., VAN DAELE, D., Poulet, C., Chavez, M., Struman, I., & Van Steen, K. (2022). Deeper insights into long-term survival heterogeneity of Pancreatic Ductal Adenocarcinoma (PDAC) patients using integrative individual-and group-level transcriptome network analyses. Scientific Reports, 12 (11027). doi:10.1038/s41598-022-14592-1

Freire, M. V., MARTIN, M., Thissen, R., Van Marcke, C., SEGERS, K., SEPULCHRE, E., LEROI, N., LETE, C., FASQUELLE, C., Radermacher, J., Gokburun, Y., COLLIGNON, J., Sacré, A., JOSSE, C., PALMEIRA, L., & BOURS, V. (2022). Case Report Series: Aggressive HR Deficient Colorectal Cancers Related to BRCA1 Pathogenic Germline Variants. Frontiers in Oncology, 12, 835581. doi:10.3389/fonc.2022.835581

Thissen, R., ARTESI, M., Durkin, K., JOSSE, C., PALMEIRA, L., & BOURS, V. (24 December 2021). Comprehensive detection of homologous recombination deficiency by Nanopore sequencing [Poster presentation]. GIGA cancer day, Liège, Belgium.

Poncin, A., Onesti, C. E., JOSSE, C., Boulet, D., Thiry, J., Bours, V., & Jerusalem, G. (August 2021). Immunity and Breast Cancer: Focus on Eosinophils. Biomedicines, 9 (9), 1087. doi:10.3390/biomedicines9091087

Uyisenga, J. P.* , Debit, A.* , Poulet, C., Frères, P., Poncin, A., Thiry, J., Mutesa, L., Jerusalem, G., Bours, V.* , & JOSSE, C.*. (03 June 2021). Differences in plasma microRNA content impair microRNA-based signature for breast cancer diagnosis in cohorts recruited from heterogeneous environmental sites. Scientific Reports, 11 (1), 11698. doi:10.1038/s41598-021-91278-0

Niemi, M., Gazon, H., JUSZCZAK, D., FADEUR, M., CAMBY, S., MEURIS, C., THYS, M., JACQUES, J., HENKET, M., BEGUIN, Y., Rahmouni, S., Lebrun, M., MOUTSCHEN, M., Misset, B., DARCIS, G., GUIOT, J., AZARZAR, S., DELLOT, P., GOFFLOT, S., ... HUYNEN, P. (Other coll.). (2021). Mapping the human genetic architecture of COVID-19. Nature, 600, 472-477. doi:10.1038/s41586-021-03767-x

Onesti, C. E., JOSSE, C., Boulet, D., Bours, V., & JERUSALEM, G. (2020). High plasmatic levels of IL-4 and IL- 13 are associated with recurrence and worse survival in breast cancer. Tumori Journal.

ONESTI, C. E., JOSSE, C., Beaumecker, B., Boulet, D., Thiry, J., BOURS, V., & JERUSALEM, G. (2020). The relative eosinophil count in breast cancer as an emerging prognostic biomarker. European Journal of Cancer. doi:10.1016/S0959-8049(20)30766-8

Jacquinet, A., Boujemla, B., FASQUELLE, C., Thiry, J., JOSSE, C., Lumaka, A., Brischoux-Boucher, E., Dubourg, C., David, V., Pasquier, L., Lehman, A., Morcel, K., Guerrier, D., & Bours, V. (2020). GREB1L variants in familial and sporadic hereditary urogenital adysplasia and Mayer-Rokitansky-Kuster-Hauser syndrome. Clinical Genetics, 98 (2), 126-137. doi:10.1111/cge.13769

ONESTI, C. E., JOSSE, C., Boulet, D., Thiry, J., Beaumecker, B., BOURS, V., & JERUSALEM, G. (2020). Blood eosinophilic relative count is prognostic for breast cancer and associated with the presence of tumor at diagnosis and at time of relapse. Oncoimmunology. doi:10.1080/2162402X.2020.1761176

Uyisenga, J., Butera, Y., Debit, A., JOSSE, C., Ainhoa, C. C., Karinganire, E., Cyuzuzo, A. P., Umurungi, N., Kalinijabo, Y., Uwimana, S., Mutesa, L., & Bours, V. (2020). Prevalence of Histological Characteristics of Breast Cancer in Rwanda in Relation to Age and Tumor Stages. Hormones and Cancer. doi:10.1007/s12672-020-00393-3

Uyisenga, J., SEGERS, K., Lumaka, A. Z., Mugenzi, P., FASQUELLE, C., Boujemla, B., JOSSE, C., Mutesa, L., & Bours, V. (2020). Screening of germline mutations in young Rwandan patients with breast cancers. Molecular Genetics and Genomic Medicine. doi:10.1002/mgg3.1500

Uyisenga, J., SEGERS, K., Butera, Y., Musoni, E., Uwimana, S., Habanabakize, T., Ruzigana, G., Mugenzi, P., JOSSE, C., BOURS, V., & Mutesa, L. (04 December 2019). Primary sarcoma of the breast in the young Rwandan females. Breast Cancer Reports, 6 (2). doi:10.7243/2057-1631-6-2

Uyisenga, J., SEGERS, K., Lumaka Zola, A., Mugenzi, P., Boujemla, B., JOSSE, C., Mutesa, L., & BOURS, V. (26 September 2019). Germline mutations in young Rwandan with breast cancers [Paper presentation]. The Joint Minimally Invasive Surgery (MIS) & 3rd Rwanda Biotechnology Conference, Kigali, Rwanda.

ONESTI, C. E., BOEMER, F., JOSSE, C., LEDUC, S., Poulet, C., BOURS, V., & JERUSALEM, G. (2019). Tryptophan catabolism differentiates breast cancer patients from healthy controls but does not predict outcome. Annals of Oncology.

Debit, A., Poulet, C., JOSSE, C., Azencott, C.-A., Jerusalem, G., Van Steen, K., & BOURS, V. (15 March 2019). TOWARDS AN ACCURATE CANCER DIAGNOSIS MODELIZATION:COMPARISON OF RANDOM FOREST STRATEGIES [Poster presentation]. 19th BeSHG meeting 15th March 2019 Liege, Belgium, Liege, Belgium.

Latge, G., Poulet, C., JOSSE, C., JERUSALEM, G., & Bours, V. (15 March 2019). Role of DNA methylation in INK4a-ARF-INK4b locus expression in breast cancer [Poster presentation]. 19th Meeting of the Belgian Society of Human Genetics, Liège, Belgium.

ONESTI, C. E., BOEMER, F., JOSSE, C., LEDUC, S., BOURS, V., & JERUSALEM, G. (2019). Tryptophan catabolism increases in breast cancer patients compared to healthy controls without affecting the cancer outcome or response to chemotherapy. Journal of Translational Medicine, 17, 239. doi:10.1186/s12967-019-1984-2

Debit, A., Poulet, C., JOSSE, C., Van Steen, K., JERUSALEM, G., Bours, V., & Azencott, C.-A. (05 October 2018). Towards an accurate cancer diagnosis modelization: Comparison of Random Forest strategies [Poster presentation]. 5th conference Bioinformatics for young international researchers expo byteMAL 2018, Liege, Belgium.

Uyisenga, J., SEGERS, K., Lumaka Zola, A., Mugenzi, P., FASQUELLE, C., Boujemla, B., JOSSE, C., Mutesa, L., & Bours, V. (20 September 2018). Screening of germline mutations in young Rwandan with breast cancer [Paper presentation]. Joint 11th Conference of African Society of Human Genetics (AfSHG)& 12th H3 Africa Consortium Meeting, Kigali, Rwanda.

ONESTI, C. E., JOSSE, C., Poncin, A., FRERES, P., Poulet, C., BOURS, V., & JERUSALEM, G. (2018). Predictive and prognostic role of peripheral blood eosinophil count in triple-negative and hormone receptor-negative/HER2-positive breast cancer patients undergoing neoadjuvant treatment. Oncotarget. doi:10.18632/oncotarget.26120

Debit, A., JOSSE, C., JERUSALEM, G., BOURS, V., & Poulet, C. (13 September 2018). Towards an accurate cancer diagnosis modelization:Comparison of Random Forest strategies [Poster presentation]. JOINT MEETING GIGA-CANCER DAY 2018 / EDT-CANCEROLOGY, Liege, Belgium.

Latgé, G., JOSSE, C., Poulet, C., Bours, V., & Jerusalem, G. (13 September 2018). Role of DNA methylation in INK4a-ARF-INK4b locus expression in breast cancer [Poster presentation]. GIGA-Cancer DAY, Liege, Belgium.

ONESTI, C. E., JOSSE, C., PONCIN, A., FRERES, P., Poulet, C., BOURS, V., & JERUSALEM, G. (13 September 2018). Predictive and prognostic role of peripheral blood eosinophil count in triple negative and hormone receptor negative/HER2 positive breast cancers patients undergoing neoadjuvant treatment [Paper presentation]. GIGA-Cancer Day 2018 / EDT-Cancerology Vascular landscape and (pre)metastatic niche in cancer biology.

Uyisenga, J., SEGERS, K., Lumaka Zola, A., Mugenzi, P., FASQUELLE, C., Boujemla, B., JOSSE, C., Mutesa, L., & Bours, V. (11 September 2018). Germline mutations in young Rwandan with breast cancers [Poster presentation]. GIGA Cancer Day, Liège, Belgium.

Costanza, B., Turtoi, A., Bellahcene, A., Hirano, T., Peulen, O., Blomme, A., Hennequiere, J., MUTIJIMA NZARAMBA, E., Boniver, J., Meuwis, M.-A., JOSSE, C., KOOPMANSCH, B., SEGERS, K., Yokobori, T., Fahmy, K., Thiry, M., COIMBRA MARQUES, C., Garbacki, N., Colige, A., ... Castronovo, V. (2018). Innovative methodology for the identification of soluble biomarkers in fresh tissues. Oncotarget, 9 (12), 10665-10680. doi:10.18632/oncotarget.24366

Freres, P., Bouznad, N., Servais, L., JOSSE, C., Wenric, S., Poncin, A., Thiry, J., Moonen, M., Oury, C., Lancellotti, P., Bours, V., & Jerusalem, G. (2018). Variations of circulating cardiac biomarkers during and after anthracycline-containing chemotherapy in breast cancer patients. BMC Cancer, 18 (1). doi:10.1186/s12885-018-4015-4

Latge, G., Poulet, C., Bours, V., JOSSE, C., & Jerusalem, G. (2018). Natural Antisense Transcripts: Molecular Mechanisms and Implications in Breast Cancers. International Journal of Molecular Sciences, 19 (1). doi:10.3390/ijms19010123

Debit, A., Wenric, S., JOSSE, C., Van Steen, K., & Bours, V. (May 2017). Normalization and correction for batch effects via RUV for RNA-seq data: practical implications for Breast Cancer Research [Poster presentation]. European Human Genetics Conference ESHG 2017, Copenhagen, Denmark.

Wenric, S., El Guendi, S., CABERG, J.-H., Bezzaou, W., Fasquelle, C., Charloteaux, B., Karim, L., Hennuy, B., FRERES, P., COLLIGNON, J., BOUKERROUCHA, M., SCHROEDER, H., Olivier, F., Jossa, V., JERUSALEM, G., JOSSE, C., & BOURS, V. (May 2017). Transcriptome wide analysis of natural antisense transcripts shows potential role in breast cancer [Poster presentation]. 50th meeting of the European Society of Human Genetics, Copenhagen, Denmark.

BOEMER, F., Fasquelle, C., D'OTREPPE DE BOUVETTE, S., JOSSE, C., DIDEBERG, V., SEGERS, K., GUISSARD, V., CAPRARO, V., Debray, F.-G., & Bours, V. (2017). A next-generation newborn screening pilot study: NGS on dried blood spots detects causal mutations in patients with inherited metabolic diseases. Scientific Reports, 7 (1), 17641. doi:10.1038/s41598-017-18038-x

Sticca, T., CABERG, J.-H., Wenric, S., Poulet, C., HERENS, C., JAMAR, M., Josse, C., El Guendi, S., MAX, S., BEGUIN, Y., GOTHOT, A., CAERS, J., & Bours, V. (2017). Genomic Studies of Multiple Myeloma Reveal an Association between X Chromosome Alterations and Genomic Profile Complexity. Genes, Chromosomes and Cancer, 56, 18-27. doi:10.1002/gcc.22397

Wenric, S., ElGuendi, S., CABERG, J.-H., Bezzaou, W., Fasquelle, C., Charloteaux, B., Karim, L., Hennuy, B., FRERES, P., COLLIGNON, J., BOUKERROUCHA, M., SCHROEDER, H., OLIVIER, F., Jossa, V., Jerusalem, G., JOSSE, C., & Bours, V. (2017). Transcriptome-wide analysis of natural antisense transcripts shows their potential role in breast cancer. Scientific Reports, 7 (1), 17452. doi:10.1038/s41598-017-17811-2

Wenric, S.* , Sticca, T.* , CABERG, J.-H., Josse, C., Fasquelle, C., HERENS, C., JAMAR, M., MAX, S., GOTHOT, A., CAERS, J., & Bours, V. (2017). Exome copy number variation detection: Use of a pool of unrelated healthy tissue as reference sample. Genetic Epidemiology, 41, 35-40. doi:10.1002/gepi.22019

FRERES, P., PONCIN, A., MOONEN, M., Josse, C., Oury, C., BOURS, V., LANCELLOTTI, P., & JERUSALEM, G. (2016). La cardiotoxicité des traitements anti-cancéreux. Revue Médicale de Liège, 71 (9), 382-387.

Josse, C., & Bours, V. (2016). MicroRNAs and Inflammation in Colorectal Cancer. In O. Slaby & G. A. Calin, Non-coding RNAs in Colorectal Cancer (1° éd, pp. 53-69). Switzerland: Springer. doi:10.1007/978-3-319-42059-2_3

Freres, P.* , Wenric, S.* , BOUKERROUCHA, M., Fasquelle, C., Thiry, J., Bovy, N., Struman, I., Geurts, P., COLLIGNON, J., SCHROEDER, H., KRIDELKA, F., LIFRANGE, E., Jossa, V., Bours, V.* , Josse, C.* , & JERUSALEM, G.*. (2015). Circulating microRNA-based screening tool for breast cancer. Oncotarget. doi:10.18632/oncotarget.6786

Boukerroucha, M., Josse, C., SEGERS, K., El Guendi, S., FRERES, P., JERUSALEM, G., & Bours, V. (26 March 2015). BRCA1 germline mutation and glioblastoma development: report of cases. BMC Cancer, 15, 181. doi:10.1186/s12885-015-1205-1

Boukerroucha, M., Josse, C., El Guendi, S., Boujemla, B., Freres, P., Marée, R., Wenric, S., SEGERS, K., COLLIGNON, J., Jerusalem, G., & Bours, V. (2015). Evaluation of BRCA1-related molecular features and microRNAs as prognostic factors for triple negative breast cancers. BMC Cancer, 15 (1), 755. doi:10.1186/s12885-015-1740-9

Boukerroucha, M., Josse, C., El Guendi, S., FRERES, P., Marée, R., Wenric, S., SEGERS, K., COLLIGNON, J., JERUSALEM, G., & BOURS, V. (2015). Genetic study of triple negative breast cancers [Poster presentation]. Impakt Breast Cancer Conference, Brussels, Belgium. doi:10.1093/annonc/mdv116.11

Bovy, N., Blomme, B., Freres, P., Dederen, S., Nivelles, O., Lion, M., Carnet, O., Martial, J., Noël, A., Thiry, M., Jerusalem, G., Josse, C., Bours, V., Tabruyn, S., & Struman, I. (2015). Endothelial exosomes contribute to the antitumor response during breast cancer neoadjuvant chemotherapy via microRNA transfer. Oncotarget. doi:10.18632/oncotarget.3520

DEBRAY, F.-G., Stumpfig, C., Vanlander, A. V., DIDEBERG, V., Josse, C., CABERG, J.-H., BOEMER, F., Bours, V., Stevens, R., Seneca, S., Smet, J., Lill, R., & van Coster, R. (2015). Mutation of the iron-sulfur cluster assembly gene IBA57 causes fatal infantile leukodystrophy. Journal of Inherited Metabolic Disease. doi:10.1007/s10545-015-9857-1

JERUSALEM, G., COLLIGNON, J., Josse, C., SCHROEDER, H., RORIVE, A., FRERES, P., LAMBERT, F., KOOPMANSCH, B., PONCIN, A., & BOURS, V. (2015). Cancer du sein : de la thérapie ciblée à la médecine personnalisée. Revue Médicale de Liège, 70 (5-6), 269-276.

FRERES, P., JOSSE, C., Bovy, N., Boukerroucha, M., Struman, I., BOURS, V., & JERUSALEM, G. (2014). Neoadjuvant chemotherapy in breast cancer induces miR-34a and miR-122 expression. Journal of Cellular Physiology. doi:10.1002/jcp.24730

JOSSE, C., Bouznad, N., Geurts, P., Irrthum, A., Huynh-Thu, V. A., Servais, L., Hego, A., Delvenne, P., Bours, V., & Oury, C. (2014). Identification of a microRNA landscape targeting the PI3K/Akt signaling pathway in inflammation-induced colorectal carcinogenesis. American Journal of Physiology - Gastrointestinal and Liver Physiology, 306, 229-43. doi:10.1152/ajpgi.00484.2012

Wenric, S., Freres, P., Josse, C., Bours, V., & Jerusalem, G. (09 December 2013). A miRNA expression based diagnostic tool for breast cancer using random forests [Poster presentation]. Benelux Bioinformatics Conference 2013.

Wenric, S., JOSSE, C., Fasquelle, C., Poulet, C., Sticca, T., Boukerroucha, M., JERUSALEM, G., & Bours, V. (15 March 2013). Exome sequencing of tumors: relevance in copy-number alteration (CNA) analysis and fixed tissue samples [Poster presentation]. 13th Annual Meeting of the Belgian Society of Human Genetics, Bruxelles, Belgium.

COLLIGNON, J., Struman, I., Tabruyn, S., Josse, C., Boukerroucha, M., JERUSALEM, G., & BOURS, V. (2011). Aspects moléculaires du cancer du sein triple négatif et les implications thérapeutiques. Revue Médicale de Liège, 66 (5-6), 393-396.

Josse, C., Schoemans, R., Niessen, N.-A., Delgaudine, M., Hellin, A.-C., Herens, C., Delvenne, P., & Bours, V. (August 2010). Systematic chromosomal aberrations found in murine bone marrow-derived mesenchymal stem cells. Stem Cells and Development, 19 (8), 1167-1173. doi:10.1089/scd.2009.0264

Schoemans, R., Aigrot, M.-S., Wu, C., Marée, R., Hong, P., Belachew, S., Josse, C., Lubetzki, C., & Bours, V. (2010). Oligodendrocyte development and myelinogenesis are not impaired by high concentrations of phenylalanine or its metabolites. Journal of Inherited Metabolic Disease, 33 (2), 113-20. doi:10.1007/s10545-010-9052-3

Zeddou, M., Briquet, A., Relic, B., Josse, C., Malaise, M., Gothot, A., Lechanteur, C., & Beguin, Y. (2010). The umbilical cord matrix is a better source of mesenchymal stem cells (MSC) than the umbilical cord blood. Cell Biology International, 34 (7), 693-701. doi:10.1042/CBI20090414

Legssyer, R., Josse, C., Piette, J., Ward, R. J., & Crichton, R. R. (2003). Changes in function of iron-loaded alveolar macrophages after in vivo administration of desferrioxamine and/or chloroquine. Journal of Inorganic Biochemistry, 94 (1-2), 36-42. doi:10.1016/S0162-0134(02)00633-5

JOSSE, C., Boelaert, J. R., Best-Belpomme, M., & Piette, J. (2001). Importance of post-transcriptional regulation of chemokine genes by oxidative stress. Biochemical Journal, 360 (Pt 2), 321-33. doi:10.1042/0264-6021:3600321

JOSSE, C., Legrand-Poels, S., Piret, B., Sluse, F., & Piette, J. (1998). Impairment of the mitochondrial electron chain transport prevents NF-kappa B activation by hydrogen peroxide. Free Radical Biology and Medicine, 25 (1), 104-112. doi:10.1016/S0891-5849(98)00057-4

Josse, C., Legrand-Poels, S., Piret, B., Sluse, F., & Piette, J. (1998). Impairment of mitochondrial functions abolishes NF-kappaB activation by an oxidative stress. Free Radical Biology and Medicine.