Publications and communications of Stéphane Schurmans

Burniat, A., Noël, A., Colige, A., Vanderplasschen, A., de Kerchove d'Exaerde, A., Kupper Cardozo, A., Van Keymeulen, A., Moens, A., Bondue, A., Herpain, A., Marchant, A., Loumaye, A., Beck, B., Van den Heyden, B., Corvilain, B., Lakaye, B., Rogister, B., Malgrange, B., Michiels, C., ... Brunko, E. (2023). Cent scientifiques répliquent à SEA (Suppression des Expériences sur l’Animal vivant) et dénoncent sa désinformation. La Libre Belgique.

Fernandes, S., Srivastava, N., Pedicone, C., Sudan, R., Luke, E. A., Dungan, O. M., Pacherille, A., Meyer, S. T., Dormann, S., Schurmans, S., Jacobsen, E., Chisholm, J. D., & Kerr, W. G. (2023). Obesity control by SHIP inhibition requires pan-paralog inhibition and an intact eosinophil compartment. iScience. doi:10.1016/j.isci.2023.106071

Ukhavov, K., Uytingco, C., Green, W., Zhang, L., Schurmans, S., & Martens, J. R. (01 March 2022). INPP5E controls ciliary localization of phospholipids and odor response in olfactory sensory neurons. Journal of Cell Science, 135 (5). doi:10.1242/jcs.258364

Marongiu, L., Mingozzi, F., Cigni, C., Marzi, R., Di Gioia, M., Garrè, M., Parazzoli, D., Sironi, L., Collini, M., Sakaguchi, R., Morii, T., Crosti, M., Moro, M., Schurmans, S., Catelani, T., Rotem, R., Colombo, M., Shears, S., Prosperi, D., ... Granucci, F. (2021). Inositol-triphosphate 3-kinase B promotes calcium mobilization and the inflammatory activity of dendritic cells. Science Signaling. doi:10.1126/scisignal.aaz2120

Michael, M., McCormick, B., Anderson, K. E., Karmakar, U., Vermeren, M., Schurmans, S., Amour, A., & Vermeren, S. (2021). The 5-phosphatase SHIP2 promotes neutrophil chemotaxis and recruitment. Frontiers in Immunology. doi:10.3389/fimmu.2021.671756

Schurmans, S., Vande Catsyne, C.-A., Desmet, C., & Moes, B. (2021). The phosphoinositide 5-phosphatase INPP5K: from gene structure to in vivo functions. Advances in Biological Regulation. doi:10.1016/j.jbior.2020.100760

Constable, S., Long, A. B., Floyd, K. A., Schurmans, S., & Caspary, T. (2020). The ciliary phosphatidylinositol phosphatase Inpp5e plays positive and negative regulatory roles in Shh signaling. Development. doi:10.1242/dev.183301

Chabrier, G., Hobson, S., Yuldasheva, N., Kearney, M. T., Schurmans, S., Pineda-Torra, I., & Gage, M. C. (2019). Aged insulin resistant macrophages reveal dysregulated cholesterol biosynthesis, a pro-inflammatory profile and reduced foam cell formation capacity. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/238491.

Guo, J., Otis, J. M., Suciu, S. K., Catalano, C., Xing, L., Constable, S., Wachten, D., Gupton, S., Lee, J., Lee, A., Blackley, K. H., Ptacek, T., Simon, J. M., Schurmans, S., Stuber, G. D., Caspary, T., & Anton, E. S. (2019). Primary Cilia Signaling Promotes Axonal Tract Development and Is Disrupted in Joubert Syndrome-Related Disorders Models. Developmental Cell, 51, 759-774. doi:10.1016/j.devcel.2019.11.005

Bakker, J., Balthazart, J., Baron, F., Beguin, Y., Bettendorff, L., Blanpain, C., Bureau, F., Caers, J., Cani, P., Cataldo, D., Cornil, C., Clercx, C., Cloots, R., Colige, A., Daube, G., De Backer, O., de Kerchove d'Exaerde, A., Desmecht, D., Desmet, C., ... Wittamer, V. (2018). La souris, le patient, et le faux expert. Décryptage d'une mystification. Le Vif. L'Express.

Erneux, C., & Schurmans, S. (2018). SHIP2. In S. Choi, Encyclopedia of Signaling Molecules (pp. 4944-4950). Springer.

Molina Ortiz, P.* , Orban, T.* , Martin, M., Habets, A., Dequiedt, F.* , & Schurmans, S.*. (2018). Rasa3 controls turnover of endothelial cell adhesion and vascular lumen integrity by a Rap1-dependent mechanism. PLoS Genetics. doi:10.1371/journal.pgen.1007195
* These authors have contributed equally to this work.

Amorim, C., Andris, F., Arckens, L., Arnould, T., Aron, S., Bakker, J., Balligand, M., Balthazart, J., Baron, F., Beck, B., Beguin, Y., Behets, C., Bellefroid, E., Bertrand, L., Bettendorff, L., Bindels, L., Blankert, B., Blanpain, C., Bondue, A., ... Wittamer, V. (2017). L’expérimentation animale reste indispensable (OPINION). La Libre Belgique.

Phua, S. C., Chiba, S., Suzuki, M., Su, E., Roberson, E. C., Pusapati, G. V., Schurmans, S., Setou, M., Rohatgi, R., Reiter, J. F., Ikegami, K., & Inoue, T. (2017). Dynamic Remodeling of membrane composition drives cell cycle through primary cilia excision. Cell, 168, 264-279. doi:10.1016/j.cell.2016.12.032

Sayyed, S. A., JOURET, F., Vermeersch, M., Pérez-Morga, D., & Schurmans, S. (2017). The lipid 5-phoshatase SHIP2 controls renal brush border ultrastructure and function by regulating ERM proteins activation. Kidney International. doi:10.1016/j.kint.2017.01.008

Sierra Potchanant, E., Cerabona, D., Sater, Z., He, Y., Sun, Z., Gehlhausen, J., Schurmans, S., Gayral, S., & Nalepa, G. (2017). INPP5E Preserves Genomic Stability through Regulation of Mitosis. Molecular and Cellular Biology, 37 (6), 500-516. doi:10.1128/MCB.00500-16

Watt, N., Gage, M., Patel, P., Viswambharan, H., Sukumar, P., Galloway, S., Yuldasheva, N., Imrie, H., Walker, A., Griffin, K., Makava, N., Skromna, A., Bridge, K., Beech, D., Schurmans, S., Wheatcroft, S., Kearney, M., & Cubbon, R. (2017). Endothelial SHIP2 suppresses Nox2 NADPH oxidase-dependent vascular oxidative stress, endothelial dysfunction and systemic insulin resistance. Diabetes, 66 (11), 2808-2821. doi:10.2337/db17-0062

Alphonse, M. P., Duong, T. T., Shumitzu, C., Hoang, L. T., McCrindle, B. W., Franco, A., Schurmans, S., Philpott, D. J., Hibberd, M. L., Burns, J. C., Kuijpers, T. W., & Yeung, R. S. M. (2016). Inositol-triphosphate-3-kinase C mediates inflammasome activation and treatment response in Kawasaki Disease. Journal of Immunology, 197, 3481-3489. doi:10.4049/jimmunol.1600388

Scoumanne, A., Molina Ortiz, P., Monteyne, D., Perez-Morga, D., Erneux, C., & Schurmans, S. (2016). Specific expression and function of inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) in wild type and knock-out mice. Advances in Biological Regulation, 62, 1-10. doi:10.1016/j.jbior.2016.03.001

Garcia-Gonzalo, F. R., Phua, S. C., Roberson, E. C., Garcia III, G., Abedin, M., Schurmans, S., Inoue, T., & Reiter, J. F. (2015). Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling. Developmental Cell, 34, 400-409. doi:10.1016/j.devcel.2015.08.001

Magnani, D., Morlé, L., Hasenpusch-Theil, K., Paschaki, M., Jacoby, M., Schurmans, S., Durand B, B., & Theil, T. (2015). The ciliogenic transcription factor Rfx3 is required for the formation of the thalamocortical tract by regulating patterning of prethalamus and ventral telencephalon. Human Molecular Genetics, 24, 2578-2593. doi:10.1093/hmg/ddv021

Molina Ortiz, P., Polizzi, S., Ramery, E., Gayral, S., Delierneux, C., Oury, C., Iwashita, S., & Schurmans, S. (2014). Rasa3 Controls Megakaryocyte Rap1 Activation, Integrin Signaling and Differentiation into Proplatelet. PLoS Genetics, 10 (6), 1004420. doi:10.1371/journal.pgen.1004420

Pirottin, D., Schurmans, S., Francois, C., Farnir, F., Closset, R., Bureau, F., & Desmet, C. (2014). Generation and validation of a mouse model for conditional inactivation of PLAGL1. In Proceedings of the 4th edition : FARAH Day 2014.

D'Amico, E., Gayral, S., Massart, C., Van Sande, J., Reiter, J. F., Dumont, J., Robaye, B., & Schurmans, S. (2013). Thyroid-specific inactivation of Kif3a alters TSH signaling pathway and leads to hypothyroidism. Journal of Molecular Endocrinology, 50, 375-387. doi:10.1530/JME-12-0219

Sokolow, S., Manto, M., Gailly, P., Molgó, J., Vandebrouck, C., Vanderwinden, J. M., Herchuelz, A., & Schurmans, S. (2004). Impaired neuromuscular transmission and skeletal muscle fiber necrosis in mice lacking Na/Ca exchanger 3. Journal of Clinical Investigation, 113, 265-273. doi:10.1172/JCI18688

Clément, S., Refetoff, S., Robaye, B., Dumont, E., & Schurmans, S. (2001). Low TSH requirement and goiter in transgenic mice overexpressing IGF-1 and IGF-1R in the thyroid gland. Endocrinology, 142 (12), 5131-5139. doi:10.1210/endo.142.12.8534

Cocea, L., De Smet, A., Saghatchian, M., Fillatreau, S., Ferradini, L., Schurmans, S., Weill, J. C., & Reynaud, A. (1999). A targeted deletion of a region upstream from the Jkappa cluster impairs kappa chain rearrangement in cis in mice and in the 103/bcl2 cell line. Journal of Experimental Medicine, 189, 1443-1450. doi:10.1084/jem.189.9.1443

Vanderhaeghen, P., Schurmans, S., Vassart, G., & Parmentier, M. (1993). Olfactory receptors are displayed on dog mature sperm cells. Journal of Cell Biology, 123, 1441-1452. doi:10.1083/jcb.123.6.1441