Publications and communications of Marielle Lebrun

Van Breedam, E., Buyle-Huybrecht, T., Govaerts, J., Meysman, P., Bours, A., Boeren, M., Di Stefano, J., Caers, T., De Reu, H., Dirkx, L., Schippers, J., Bartholomeus, E., Lebrun, M., Sadzot, C., Rybakowska, P., Alarcón-Riquelme, M. E., Marañón, C., Laukens, K., Delputte, P., ... Ponsaerts, P. (2023). Lack of strong innate immune reactivity renders macrophages alone unable to control productive Varicella-Zoster Virus infection in an isogenic human iPSC-derived neuronal co-culture model. Frontiers in Immunology, 14, 1177245. doi:10.3389/fimmu.2023.1177245

Boeren, M., Van Breedam, E., Buyle-Huybrecht, T., Lebrun, M., Meysman, P., Sadzot, C., Van Tendeloo, V. F., Mortier, G., Laukens, K., Ogunjimi, B., Ponsaerts, P., & Delputte, P. (14 November 2022). Activation of Interferon-Stimulated Genes following Varicella-Zoster Virus Infection in a Human iPSC-Derived Neuronal In Vitro Model Depends on Exogenous Interferon-α. Viruses, 14 (11), 2517. doi:10.3390/v14112517

Sanchez Gil, J., Dubois, M., Neirinckx, V., LOMBARD, A., Coppieters't Wallant, N., D'arrigo, P., Isci, D., Aldenhoff, T., Brouwers, B., Lassence, C., ROGISTER, B., Lebrun, M., & Sadzot, C. (2022). Nanobody-based retargeting of an oncolytic herpesvirus for eliminating CXCR4+ GBM cells: a proof-of-principle. Molecular Therapy: Oncolytics. doi:10.1016/j.omto.2022.06.002

D'arrigo, P., Sanchez Gil, J., Dubois, M., Lebrun, M., ROGISTER, B., & Sadzot, C. (02 August 2021). An armed oncolytic herpesvirus to counteract gioblastoma stem-like cells functions [Poster presentation]. International Herpesvirus Workshop.

Niemi, M., Gazon, H., JUSZCZAK, D., FADEUR, M., CAMBY, S., MEURIS, C., THYS, M., JACQUES, J., HENKET, M., BEGUIN, Y., Rahmouni, S., Lebrun, M., MOUTSCHEN, M., Misset, B., DARCIS, G., GUIOT, J., AZARZAR, S., DELLOT, P., GOFFLOT, S., ... HUYNEN, P. (Other coll.). (2021). Mapping the human genetic architecture of COVID-19. Nature, 600, 472-477. doi:10.1038/s41586-021-03767-x

Lambert, J., Sadzot, C., Lebrun, M., & Thiry, M. (Other coll.). (19 December 2019). Varicella Zoster Virus ORF9p: hijacker of the autophagy pathway? [Paper presentation]. Belvir 2019, Brussels, Belgium.

Sanchez Gil, J., Lebrun, M., Allegro, A., Chevigné, A., ROGISTER, B., & Sadzot, C. (2019). Targeting of CXCR4+ Glioblastoma initiating cells with a retargeted oncolytic herpesvirus [Poster presentation]. 12th International Oncolytic Virus conference, Rochester, United States - Minnesota.

Lambert, J., Lebrun, M., Riva, L., Sanchez Gil, J., Sadzot-Delvaux, C., Andrei, G. (Other coll.), & Snoeck, R. (Other coll.). (29 July 2017). Study of the role of the complex formed by the Varicella Zoster virus ORF9p and the cellular Adaptin Protein-1 in the secondary egress [Poster presentation]. IHW 2017, Ghent, Belgium.

Lebrun, M., riva, L., lambert, J., Rambout, X., Thiry, M., blondeau, C., Twizere, J.-C., Dequiedt, F., & Sadzot-Delvaux, C. (20 May 2016). Role of Varicella Zoster virus ORF9p in the secondary egress : importance of its interaction with the cellular Adaptin Protein-1 [Poster presentation]. 2015 Colorado Alphaherpesvirus Latency Society Symposium, Vail, United States - Colorado.

Rambout, X., Detiffe, C., Bruyr, J., Mariavelle, E., Cherkaoui, M., Brohee, S., Demoitie, P., Lebrun, M., Soin, R., Lesage, B., Guedri, K., Beullens, M., Bollen, M., Farazi, T. A., Kettmann, R., Struman, I., Hill, D. E., Vidal, M., Kruys, V., ... Dequiedt, F. (2016). The transcription factor ERG recruits CCR4-NOT to control mRNA decay and mitotic progression. Nature Structural and Molecular Biology. doi:10.1038/nsmb.3243

Lebrun, M. (2014). Nuclear capsid aggregates of Varicella-Zoster virus: assembly sites or dead-end depot? [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/168326

Lebrun, M., Thelen, N., Thiry, M., Riva, L., Ote, I., Condé, C., Vandevenne, P., Di Valentin, E., BONTEMS, S., & Sadzot-Delvaux, C. (2014). Varicella-zoster virus induces the formation of dynamic nuclear capsid aggregates. Virology, 454-455, 311-27. doi:10.1016/j.virol.2014.02.023

Riva, L., Thiry, M., Lebrun, M., L'Homme, L., Piette, J., & Sadzot-Delvaux, C. (2014). Deletion of the ORF9p acidic cluster impairs the nuclear egress of Varicella-zoster virus capsids. Journal of Virology. doi:10.1128/JVI.03215-14

Riva, L., Thiry, M., BONTEMS, S., Joris, A., Piette, J., Lebrun, M., & Sadzot-Delvaux, C. (28 January 2013). ORF9p phosphorylation by ORF47p is crucial for the formation and egress of Varicella-­‐ Zoster Virus viral particles [Poster presentation]. GIGA-Day, Liège, Belgium.

Condé, C., Rambout, X., Lebrun, M., Lecat, A., Di Valentin, E., Dequiedt, F., Piette, J., Gloire, G., & Legrand, S. (2012). The inositol phosphatase SHIP-1 inhibits NOD2-induced NF-κB activation by disturbing the interaction of XIAP with RIP2. PLoS ONE. doi:10.1371/journal.pone.0041005

Vandevenne, P., Lebrun, M., El Mjiyad, N., Ote, I., Di Valentin, E., Habraken, Y., Dortu, E., Piette, J., & Sadzot-Delvaux, C. (February 2011). The varicella-zoster virus ORF47 kinase interferes with host innate immune response by inhibiting the activation of IRF3. PLoS ONE, 9 (2). doi:10.1371/journal.pone.0016870

Ote, I., Vandevenne, P., Bontems, S., Medina-Palazon, C., Manet, E., Piette, J., Lebrun, M., & Sadzot-Delvaux, C. (18 November 2009). Varicella-Zoster Virus IE4 Protein Interacts with SR Proteins and Exports mRNAs through the TAP/NXF1 Pathway. PLoS ONE, 4 (11), 7882. doi:10.1371/journal.pone.0007882