Van Breedam, E., Buyle-Huybrecht, T., Govaerts, J., Meysman, P., Bours, A., Boeren, M., Di Stefano, J., Caers, T., De Reu, H., Dirkx, L., Schippers, J., Bartholomeus, E., Lebrun, M., Sadzot, C., Rybakowska, P., Alarcón-Riquelme, M. E., Marañón, C., Laukens, K., Delputte, P., ... Ponsaerts, P. (2023). Lack of strong innate immune reactivity renders macrophages alone unable to control productive Varicella-Zoster Virus infection in an isogenic human iPSC-derived neuronal co-culture model. Frontiers in Immunology, 14, 1177245. doi:10.3389/fimmu.2023.1177245 |
Boeren, M., Van Breedam, E., Buyle-Huybrecht, T., Lebrun, M., Meysman, P., Sadzot, C., Van Tendeloo, V. F., Mortier, G., Laukens, K., Ogunjimi, B., Ponsaerts, P., & Delputte, P. (14 November 2022). Activation of Interferon-Stimulated Genes following Varicella-Zoster Virus Infection in a Human iPSC-Derived Neuronal In Vitro Model Depends on Exogenous Interferon-α. Viruses, 14 (11), 2517. doi:10.3390/v14112517 |
Sanchez Gil, J., Dubois, M., Neirinckx, V., LOMBARD, A., Coppieters't Wallant, N., D'arrigo, P., Isci, D., Aldenhoff, T., Brouwers, B., Lassence, C., ROGISTER, B., Lebrun, M., & Sadzot, C. (2022). Nanobody-based retargeting of an oncolytic herpesvirus for eliminating CXCR4+ GBM cells: a proof-of-principle. Molecular Therapy: Oncolytics. doi:10.1016/j.omto.2022.06.002 |
D'arrigo, P., Sanchez Gil, J., Dubois, M., Lebrun, M., ROGISTER, B., & Sadzot, C. (02 August 2021). An armed oncolytic herpesvirus to counteract gioblastoma stem-like cells functions [Poster presentation]. International Herpesvirus Workshop. |
Boeren, M., Buyle-Huybrecht, T., Van Breedam, E., Nijak, A., Alaerts, M., Lebrun, M., Sadzot, C., Van Tendeloo, V., Loeys, B., Mortier, G., Laukens, K., Ogunjimi, B., Ponsaerts, P., & Delputte, P. (August 2021). Interferon-α limits varicella-zoster virus (VZV) spread in human iPSC-derived neuronal cultures upon axonal infection [Paper presentation]. IHW2021: 45th International Herpesvirus Workshop. |
Buyle-Huybrechts, T., Boeren, M., Van Breedam, E., Perik, M., Lebrun, M., Sadzot, C., Rybakowska, P., Maranon Lizana, C., Loeys, B., Laukens, K., Delputte, P., Ponsaerts, P., & Ongunjimi, B. (August 2021). Suppression of Varicella Zoster Virus Spread by Macrophages in a hiPSC-derived Neuro-Immune Cell Culture Model [Paper presentation]. IHW2021: 45th International Herpesvirus Workshop. |
Lebrun, M., Lambert, J., Zhou, M., Jassin, M., Oliver, S., Arvin, A., & Sadzot, C. (August 2021). The role of ORF9p in VZV-induced cell-cell fusion [Paper presentation]. 45th annual International Herpesvirus Workshop. |
D'arrigo, P., Sanchez Gil, J., Lebrun, M., Rogister, B., & Sadzot, C. (01 April 2021). An oncolytic herpesvirus to counteract Glioblastoma Stem Cells function [Paper presentation]. Journée des chercheurs Télévie, Belgium. |
Niemi, M., Gazon, H., JUSZCZAK, D., FADEUR, M., CAMBY, S., MEURIS, C., THYS, M., JACQUES, J., HENKET, M., BEGUIN, Y., Rahmouni, S., Lebrun, M., MOUTSCHEN, M., Misset, B., DARCIS, G., GUIOT, J., AZARZAR, S., DELLOT, P., GOFFLOT, S., ... HUYNEN, P. (Other coll.). (2021). Mapping the human genetic architecture of COVID-19. Nature, 600, 472-477. doi:10.1038/s41586-021-03767-x |
Sanchez Gil, J., D'arrigo, P., Lebrun, M., Isci, D., Coppieters, N., Rogister, B., Chevigné, A., & Sadzot, C. (2021). Targeting of CXCR4+ Glioblastoma initiating cells with a retargeted oncolytic herpesvirus [Poster presentation]. Journée des chercheurs Télévie. |
Sanchez Gil, J., D'arrigo, P., Neirinckx, V., Isci, D., Brouwers, B., LOMBARD, A., Rogister, B., Lebrun, M., & Sadzot, C. (2021). Targeting of CXCR4+ Glioblastoma initiating cells with a retargeted Oncolytic Herpesvirus (oHSV): proof of concept [Paper presentation]. IHW2021: 45th International Herpesvirus Workshop. |
D'arrigo, P., Sanchez Gil, J., Lebrun, M., ROGISTER, B., & Sadzot, C. (18 December 2020). An oncolytic herpesvirus to counteract Glioblastoma Stem Cells function [Poster presentation]. BELVIR. |
Sanchez Gil, J., Lebrun, M., Rogister, B., Chevigné, A., & Sadzot, C. (2020). Targeting of CXCR4+ Glioblastoma initiating cells with a retargeted oncolytic herpesvirus [Poster presentation]. Journée des chercheurs Télévie, Bruxelles, Belgium. |
Sanchez Gil, J., Lebrun, M., Rogister, B., Chevigné, A., & Sadzot, C. (2020). Targeting of CXCR4+ Glioblastoma initiating cells with a retargeted oncolytic herpesvirus [Poster presentation]. BELVIR. |
Lambert, J., Sadzot, C., Lebrun, M., & Thiry, M. (Other coll.). (19 December 2019). Varicella Zoster Virus ORF9p: hijacker of the autophagy pathway? [Paper presentation]. Belvir 2019, Brussels, Belgium. |
Sanchez Gil, J., Lebrun, M., Allegro, A., Chevigné, A., ROGISTER, B., & Sadzot, C. (2019). Targeting of CXCR4+ Glioblastoma initiating cells with a retargeted oncolytic herpesvirus [Poster presentation]. 12th International Oncolytic Virus conference, Rochester, United States - Minnesota. |
Lebrun, M., Lambert, J., Riva, L., Thelen, N., Rambout, X., Blondeau, C., Thiry, M., Snoeck, R., Twizere, J.-C., Dequiedt, F., Andrei, G., & Sadzot-Delvaux, C. (17 July 2018). Varicella Zoster Virus ORF9p binding to cellular adaptor protein complex-1 is important for viral infectivity. Journal of Virology, 92 (15). doi:10.1128/JVI.00295-18 |
Lebrun, M., Blondeau, C., Riva, L., Lambert, J., Thiry, M., & Sadzot-Delvaux, C. (02 August 2017). The role of the tegument protein ORF9p and its phosphorylation status in VZV nuclear egress [Poster presentation]. 42nd International Herpesvirus Workshop. |
Lambert, J., Lebrun, M., Riva, L., Sanchez Gil, J., Sadzot-Delvaux, C., Andrei, G. (Other coll.), & Snoeck, R. (Other coll.). (29 July 2017). Study of the role of the complex formed by the Varicella Zoster virus ORF9p and the cellular Adaptin Protein-1 in the secondary egress [Poster presentation]. IHW 2017, Ghent, Belgium. |
Lebrun, M., blondeau, C., Riva, L., Lambert, J., Thiry, M., & Sadzot, B. (29 July 2017). The role of the tegument protein ORF9p and its phosphorylation status in VZV nuclear egress [Paper presentation]. 42nd International Herpesvirus Workshop. |
Lambert, J., Lebrun, M., Sanchez-Gil, J., Riva, L., & Sadzot, C. (11 May 2017). CHARACTERIZATION OF THE COMPLEX FORMED BY THE VARICELLA ZOSTER VIRUS ORF9P AND THE CELLULAR ADAPTIN PROTEIN-1 AND ITS ROLE IN THE SECONDARY EGRESS [Poster presentation]. Interuniversity PhD Student Day, Liège, Belgium. |
Thiry, M., Bourmeyster, N., Dommes, J., Lebrun, M., Rigo, P., & Jaspar-Versali, M.-F. (2016). Biologie moléculaire: exercices et méthodes. Paris, France: Dunod. |
Lebrun, M., riva, L., lambert, J., Rambout, X., Thiry, M., blondeau, C., Twizere, J.-C., Dequiedt, F., & Sadzot-Delvaux, C. (20 May 2016). Role of Varicella Zoster virus ORF9p in the secondary egress : importance of its interaction with the cellular Adaptin Protein-1 [Poster presentation]. 2015 Colorado Alphaherpesvirus Latency Society Symposium, Vail, United States - Colorado. |
Rambout, X., Detiffe, C., Bruyr, J., Mariavelle, E., Cherkaoui, M., Brohee, S., Demoitie, P., Lebrun, M., Soin, R., Lesage, B., Guedri, K., Beullens, M., Bollen, M., Farazi, T. A., Kettmann, R., Struman, I., Hill, D. E., Vidal, M., Kruys, V., ... Dequiedt, F. (2016). The transcription factor ERG recruits CCR4-NOT to control mRNA decay and mitotic progression. Nature Structural and Molecular Biology. doi:10.1038/nsmb.3243 |
Lebrun, M., riva, L., Rambout, X., Thiry, M., Blondeau, C., Twizere, J.-C., Dequiedt, F., & Sadzot-Delvaux, C. (26 July 2015). Identification of VZV ORF9p potential cellular partners that could be important for the viral egress [Poster presentation]. 40th international herpesvirus workshop, boise, United States - Idaho. |
Lebrun, M., Thiry, M., & Sadzot-Delvaux, C. (15 May 2015). Varicella-Zoster Virus (VZV) assemblons interplay with PML bodies [Poster presentation]. 2015 alphaherpesvirus latency symposium, vail, United States - Colorado. |
Lebrun, M. (24 March 2015). Varicella-Zoster Virus (VZV) capsids trapped in PML-bodies: antiviral defense or stress response? [Paper presentation]. séminaire FARAH. |
Blondeau, C., Istaz, B., Lebrun, M., thiry, M., Colson, C., & Sadzot-Delvaux, C. (2015). Role of Kinases in VZV Nuclear Egress [Poster presentation]. 40th Annual International Herpesvirus Workshop, boise, United States. |
Lebrun, M. (2014). Nuclear capsid aggregates of Varicella-Zoster virus: assembly sites or dead-end depot? [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/168326 |
Lebrun, M., Thelen, N., Thiry, M., Riva, L., Ote, I., Condé, C., Vandevenne, P., Di Valentin, E., BONTEMS, S., & Sadzot-Delvaux, C. (2014). Varicella-zoster virus induces the formation of dynamic nuclear capsid aggregates. Virology, 454-455, 311-27. doi:10.1016/j.virol.2014.02.023 |
Riva, L., Thiry, M., Lebrun, M., L'Homme, L., Piette, J., & Sadzot-Delvaux, C. (2014). Deletion of the ORF9p acidic cluster impairs the nuclear egress of Varicella-zoster virus capsids. Journal of Virology. doi:10.1128/JVI.03215-14 |
Rambout, X., Simonis, N., Brohée, S., Cherkaoui, M., Lebrun, M., Vidal, M., Kruys, V., Twizere, J.-C., Soin, R., & Dequiedt, F. (28 January 2013). Interactomic map of the Ets factors family : Identification of unexpected functions in mRNA processing [Poster presentation]. GIGA Day 2013. |
Riva, L., Thiry, M., BONTEMS, S., Joris, A., Piette, J., Lebrun, M., & Sadzot-Delvaux, C. (28 January 2013). ORF9p phosphorylation by ORF47p is crucial for the formation and egress of Varicella-‐ Zoster Virus viral particles [Poster presentation]. GIGA-Day, Liège, Belgium. |
Martin, M., Geudens, I., Bruyr, J., Potente, M., Bleuart, A., Lebrun, M., Simonis, N., Deroanne, C., Twizere, J.-C., Soubeyran, P., Peixoto, P., Mottet, D., Janssens, V., Hofmann, W.-K., Claes, F., Carmeliet, P., Kettmann, R., Gerhardt, H., & Dequiedt, F. (2013). PP2A regulatory subunit Balpha controls endothelial contractility and vessel lumen integrity via regulation of HDAC7. EMBO Journal. doi:10.1038/emboj.2013.187 |
Riva, L., Thiry, M., BONTEMS, S., Joris, A., Piette, J., Lebrun, M.* , & Sadzot-Delvaux, C.*. (2013). ORF9p phosphorylation by ORF47p is crucial for the formation and egress of the Varicella-zoster virus (VZV) viral particles. Journal of Virology, 87 (5), 2868-2881. doi:10.1128/JVI.02757-12 * These authors have contributed equally to this work. |
Rambout, X., Simonis, N., Demoitié, P., Cherkaoui, M., Lebrun, M., Vidal, M., Kruys, V., Twizere, J.-C., & Dequiedt, F. (2012). Interactomic map of the Ets factors family : Identification of unexpected functions in mRNA processing. In Keystone symposium - Protein-RNA Interactions in Biology and Disease (C1). |
Condé, C., Rambout, X., Lebrun, M., Lecat, A., Di Valentin, E., Dequiedt, F., Piette, J., Gloire, G., & Legrand, S. (2012). The inositol phosphatase SHIP-1 inhibits NOD2-induced NF-κB activation by disturbing the interaction of XIAP with RIP2. PLoS ONE. doi:10.1371/journal.pone.0041005 |
Lebrun, M., Riva, L., Ote, I., Vandevenne, P., Di Valentin, E., Thiry, M., BONTEMS, S., & Sadzot-Delvaux, C. (2012). Varicella-Zoster virus (VZV) capsids trapped in PML-bodies: antiviral defense or stress response? [Poster presentation]. GIGA-DAY. |
Lebrun, M., Ote, I., Riva, L., Vandevenne, P., Condé, C., Piette, J., BONTEMS, S., & Sadzot-Delvaux, C. (July 2011). Characterization of the Varicella-Zoster Virus Tegument proteins encoded by ORF7, 21, 22 and 38 [Poster presentation]. 36th Annual International Herpesvirus Workshop / Varicella Zoster Virus satellite meeting, Gdansk, Poland. |
Riva, L., Lebrun, M., BONTEMS, S., Di Valentin, E., Piette, J., & Sadzot-Delvaux, C. (July 2011). Determination of the biological function of the Varicella Zoster Virus ORF9p [Poster presentation]. 36th Annual International Herpesvirus Workshop / Varicella Zoster Virus satellite meeting, Gdansk, Poland. |
Vandevenne, P., Lebrun, M., El Mjiyad, N., Ote, I., Di Valentin, E., Habraken, Y., Dortu, E., Piette, J., & Sadzot-Delvaux, C. (February 2011). The varicella-zoster virus ORF47 kinase interferes with host innate immune response by inhibiting the activation of IRF3. PLoS ONE, 9 (2). doi:10.1371/journal.pone.0016870 |
Ote, I., Vandevenne, P., Bontems, S., Medina-Palazon, C., Manet, E., Piette, J., Lebrun, M., & Sadzot-Delvaux, C. (18 November 2009). Varicella-Zoster Virus IE4 Protein Interacts with SR Proteins and Exports mRNAs through the TAP/NXF1 Pathway. PLoS ONE, 4 (11), 7882. doi:10.1371/journal.pone.0007882 |
Liao, S., Bentley, K., Lebrun, M., Lesslauer, W., Ruddle, F. H., & Ruddle, N. H. (2007). Transgenic LacZ under control of Hec-6st regulatory sequences recapitulates endogenous gene expression on high endothelial venules. Proceedings of the National Academy of Sciences of the United States of America, 104 (11), 4577-82. doi:10.1073/pnas.0700334104 |
Juan, A. H., Lei, H. Y., Bhargava, P., Lebrun, M., & Ruddle, F. H. (2006). Multiple roles of Hoxc8 in skeletal development. Annals of the New York Academy of Sciences, 1068, 87-94. doi:10.1196/annals.1346.046 |