Dhehibi, A., Terrak, M., Seddik, M.-M., Hammadi, M., & Salhi, I. (March 2024). Development of a bispecific Nanobody anti-F17 fimbria as a potential therapeutic tool. Protein Expression and Purification, 215, 106411. doi:10.1016/j.pep.2023.106411 |
Dhehibi, A., Allaoui, A., Raouafi, A., Terrak, M., Bouhaouala-Zahar, B., Hammadi, M., Raouafi, N., & Salhi, I. (20 February 2023). Nanobody-Based Sandwich Immunoassay for Pathogenic Escherichia coli F17 Strain Detection. Biosensors, 13 (2), 299. doi:10.3390/bios13020299 |
Li, Y.* , Boes, A.* , Cui, Y., Zhao, S., Liao, Q., Gong, H., Breukink, E., Lutkenhaus, J., Terrak, M.* , & Du, S.*. (2022). Identification of the potential active site of the septal peptidoglycan polymerase FtsW. PLoS Genetics, 18 (1), 1009993. doi:10.1371/journal.pgen.1009993 * These authors have contributed equally to this work. |
Terrak, M., & Frère, J.-M. (2021). β‐Lactam Antibiotics. In S. Offermanns & W. Rosenthal (Eds.), Encyclopedia of Molecular Pharmacology (3rd ed. Encyclopedia of Molecular Pharmacology). Springer, Cham. doi:10.1007/978-3-030-21573-6_29-1 |
Boes, A., Brunel, J. M., Derouaux, A., Kerff, F., Bouhss, A., Touze, T., Breukink, E., & Terrak, M. (2020). Squalamine and Aminosterol Mimics Inhibit the Peptidoglycan Glycosyltransferase Activity of PBP1b. Antibiotics. doi:10.3390/antibiotics9070373 |
Boes, A., Kerff, F., Herman, R., Touze, T., Breukink, E., & Terrak, M. (2020). Biochemical and structural insights into the activation of PBP1b by the essential domain of FtsN. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/248617. |
Boes, A., Kerff, F., Herman, R., Touze, T., Breukink, E., & Terrak, M. (2020). The bacterial cell division protein fragment (E)FtsN binds to and activates the major peptidoglycan synthase PBP1b. The Journal of biological chemistry, 295 (52), 18256-18265. doi:10.1074/jbc.RA120.015951 |
Boes, A., Olatunji, S., Mohammadi, T., Breukink, E., & Terrak, M. (2020). Fluorescence anisotropy assays for high throughput screening of compounds binding to lipid II, PBP1b, FtsW and MurJ. Scientific Reports, 10 (1), 6280. doi:10.1038/s41598-020-63380-2 |
Pazos, M., Peters, K., Boes, A., Safaei, Y., Kenward, C., Caveney, N. A., Laguri, C., Breukink, E., Strynadka, N. C. J., Simorre, J.-P., Terrak, M., & Vollmer, W. (2020). SPOR Proteins Are Required for Functionality of Class A Penicillin-Binding Proteins in Escherichia coli. MBio, 11 (6). doi:10.1128/mBio.02796-20 |
Boes, A., & Terrak, M. (December 2019). Biochemical and structural insights into the activation of PBP1b by the essential domain of FtsN [Poster presentation]. Symposium Currents trends in membrane protein biophysics. |
Boes, A., Terrak, M., Kerff, F., Touzé, T., & Breukink, E. (15 November 2019). Biochemical and structural insights into the interaction of the essential domain of FtsN with PBP1b [Poster presentation]. SFMBBM. |
Terrak, M. (11 June 2019). Regulation of the peptidoglycan synthases PBPs within the divisome [Paper presentation]. EMBO Workshop Bacterial cell division: Closing the gap, Lund, Sweden. |
Boes, A., olatunji, S., Breukink, E., & Terrak, M. (08 January 2019). Regulation of the Peptidoglycan Polymerase Activity of PBP1b by Antagonist Actions of the Core Divisome Proteins FtsBLQ and FtsN. MBio, 10. doi:10.1128/mBio.01912-18 |
Terrak, M. (2019). Bacterial cell wall biosynthesis and regulation [Paper presentation]. Invitation de UM6P, Ben Guerir, Morocco. |
Boes, A., & Terrak, M. (November 2018). Interaction and activities regulation within the septal peptidoglycan enzymatic core in E. coli [Poster presentation]. SFMBBM. |
Dahmane, I., Montagner, C., Matagne, A., Dumbre, S., Herdewijn, P., & Terrak, M. (2018). Peptidoglycan glycosyltransferase-ligand binding assay based on tryptophan fluorescence quenching. Biochimie. doi:10.1016/j.biochi.2018.06.010 |
Boes, A., & Terrak, M. (December 2017). Study of the interactions and activities within the enzymatic core of the E. coli divisome [Paper presentation]. IPROS meeting. |
Boes, A., & Terrak, M. (25 September 2017). Antagonist activities of the FtsQLB complex and FtsN on peptidoglycan synthesis suggests a regulation mechanism of the divisome [Poster presentation]. Greatwall symposium 2017. |
Olatunji, S., & Terrak, M. (15 May 2017). Identification and characterization of interactions between MurJ (MviN) and proteins of bacterial division and elongation machineries in E. coli [Poster presentation]. Membrane Proteins: Structure & Function. Suzhou, China. May 15-19, 2017. |
Leclercq, S., Derouaux, A., Olatunji, S., Fraipont, C., Egan, A. J. F., Vollmer, W., Breukink, E., & Terrak, M. (24 February 2017). Interplay between Penicillin-binding proteins and SEDS proteins promotes bacterial cell wall synthesis. Scientific Reports, 7, 43306. doi:10.1038/srep43306 |
Collienne, S., Mouithys-Mickalad, A., Terrak, M., & Hoebeke, M. (20 May 2016). Electron paramagnetic resonance and fluorescence studies on potential anticancer properties of two Ru(II) complexes [Poster presentation]. 24th Benelux EPR society Meeting, Liège, Belgium. |
Sauvage, E., & Terrak, M. (17 February 2016). Glycosyltransferases and Transpeptidases/Penicillin-Binding Proteins: Valuable Targets for New Antibacterials. Antibiotics, 5 (1). doi:10.3390/antibiotics5010012 |
Sosic, I., Anderluh, M., Sova, M., Gobec, M., Mlinaric Rascan, I., Derouaux, A., Amoroso, A. M., Terrak, M., Breukink, E., & Gobec, S. (2015). Structure-Activity Relationships of Novel Tryptamine-Based Inhibitors of Bacterial Transglycosylase. Journal of Medicinal Chemistry. doi:10.1021/acs.jmedchem.5b01482 |
Leclercq, S., Olatunji, S., Derouaux, A., Breukink, E., & Terrak, M. (September 2015). In vitro reconstitution of multi-proteins complexes of the peptidoglycan synthesis machinery of Escherichia coli [Poster presentation]. 4th Great Wall Symposium, Florence, Italy. |
Collienne, S., Terrak, M., Mouithys-Mickalad, A., Delaude, L., & Hoebeke, M. (22 May 2015). Electron paramagnetic resonance and fluorescence studies on potential anticancer properties of two new Ru(II) complexes : preliminary results [Poster presentation]. 23rd Benelux EPR Society Meeting, Ghent, Belgium. |
Bury, D., Dahmane, I., Derouaux, A., Dumbre, S., Herdewijn, P., Matagne, A., Breukink, E., Mueller-Seitz, E., Petz, M., & Terrak, M. (2015). Positive cooperativity between acceptor and donor sites of the peptidoglycan glycosyltransferase. Biochemical Pharmacology, 93 (2), 141-50. doi:10.1016/j.bcp.2014.11.003 |
Derouaux, A., Terrak, M., Den Blaauwen, T., & Vollmer, W. (2014). Bacterial cell wall growth, shape and division. In Bacterial Membranes: Structural and Molecular Biology. Horizon Scientific Press. |
Leclercq, S., Derouaux, A., & Terrak, M. (23 September 2013). Study of the activities of PBP3/PBP1b from Escherichia coli and the effect of the immediate divisome partners [Poster presentation]. The 3rd Great Wall Symposium “The Dynamics of Peptidoglycan Structure and Function: New Insights into the 'Great Wall', Paris, France. |
Arguelles Arias, A., Ongena, M., Devreese, B., Terrak, M., Joris, B., & Fickers, P. (2013). Characterization of amylolysin, a novel lantibiotic from Bacillus amyloliquefaciens GA1. PLoS ONE, 8 (12). doi:10.1371/journal.pone.0083037 |
Derouaux, A., Sauvage, E., & Terrak, M. (2013). Peptidoglycan glycosyltransferase substrate mimics as templates for the design of new antibacterial drugs. Frontiers in Immunology, 4, 78. doi:10.3389/fimmu.2013.00078 |
Rocaboy, M., Herman, R., Sauvage, E., Remaut, H., Moonens, K., Terrak, M., Charlier, P., & Kerff, F. (2013). The crystal structure of the cell division amidase AmiC reveals the fold of the AMIN domain, a new peptidoglycan binding domain. Molecular Microbiology. doi:10.1111/mmi.12361 |
Terrak, M. (11 December 2012). Exploration of the Glycosyltransferases as new antibacterial target [Paper presentation]. Invited conference, Ljubljana, Slovenia. |
Kerff, F., Rocaboy, M., Herman, R., Sauvage, E., Moonens, K., Remaut, H., Charlier, P., & Terrak, M. (25 June 2012). Structure of the E. coli amidase AmiC and its activation by the LytM cofactor NlpD [Poster presentation]. Gordon Research Conference on bacterial Cell Surfaces, West Dover, VT, United States. |
Banzhaf, M., van den Berg van Saparoea, B., Terrak, M., Fraipont, C., Egan, A., Philippe, J., Zapun, A., Breukink, E., Nguyen-Distèche, M., den Blaauwen, T., & Vollmer, W. (2012). Cooperativity of peptidoglycan synthases active in bacterial cell elongation. Molecular Microbiology, 85 (1), 179-94. doi:10.1111/j.1365-2958.2012.08103.x |
Dumbre, S., Derouaux, A., Lescrinier, E., Piette, A., Joris, B., Terrak, M., & Herdewijn, P. (2012). Synthesis of Modified Peptidoglycan Precursor Analogues for the Inhibition of Glycosyltransferase. Journal of the American Chemical Society. doi:10.1021/ja302099u |
Terrak, M., Herdewijn, & Bumbre, S. (29 September 2011). Specificity of E. coli PBP1b for the substrate and inhibition of its GT activity [Paper presentation]. The 2d Great Wall Symposium “The Dynamics of Peptidoglycan Structure and Function: New Insights into the 'Great Wall', Lisbon, Portugal. |
Terrak, M., Breukink, E., Gobec, S., Chopra, I., & Vernet, T. (26 May 2011). Tryptamine-derived compounds as antibacterial agents. |
Derouaux, A., Turk, S., Olrichs, N. K., Gobec, S., Breukink, E., Amoroso, A. M., Offant, J., Bostock, J., Mariner, K., Chopra, I., Vernet, T., Zervosen, A., Joris, B., Frère, J.-M., Nguyen Van, M., & Terrak, M. (2011). Small molecule inhibitors of peptidoglycan synthesis targeting the lipid II precursor. Biochemical Pharmacology, 81 (9), 1098-105. doi:10.1016/j.bcp.2011.02.008 |
Reed, P., Veiga, H., Jorge, A. M., Terrak, M., & Pinho, M. G. (2011). Monofunctional transglycosylases are not essential for Staphylococcus aureus cell wall synthesis. Journal of Bacteriology, 193 (10), 2549-56. doi:10.1128/JB.01474-10 |
Offant, J., Terrak, M., Derouaux, A., Breukink, E., Nguyen Van, M., Zapun, A., & Vernet, T. (2010). Optimization of conditions for the glycosyltransferase activity of penicillin-binding protein 1a from Thermotoga maritima. FEBS Journal, 277 (20), 4290-8. doi:10.1111/j.1742-4658.2010.07817.x |
Derouaux, A., Turk, S., Offant, J., Amoroso, A. M., Breukink, E., Bostock, J., Chopra, I., Zervosen, A., Joris, B., Nguyen Van, M., Vernet, T., Gobec, S., & Terrak, M. (November 2009). Identification and characterization of novel peptidoglycan glycosyltransferase inhibitors with antibacterial activity [Poster presentation]. Exploration and exploitation of bacterial cell wall biosynthesis, Warwick, United Kingdom. |
Terrak, M. (15 December 2008). Penicillin-binding proteins: function in the bacterial cell wall assembly and their targeting with antibacterial agents [Paper presentation]. Invited conference, Varese, Italy. |
Derouaux, A., Wolf, B., Fraipont, C., Breukink, E., Nguyen-Distèche, M., & Terrak, M. (March 2008). The Monofunctional Glycosyltransferase of Escherichia Coli Localizes to the Cell Division Site and Interacts with Penicillin-Binding Protein 3, FtsW, and FtsN. Journal of Bacteriology, 190 (5), 1831-4. doi:10.1128/JB.01377-07 |
Sauvage, E.* , Kerff, F.* , Terrak, M., Ayala, J. A., & Charlier, P. (March 2008). The Penicillin-Binding Proteins: Structure and Role in Peptidoglycan Biosynthesis. FEMS Microbiology Reviews, 32 (2), 234-58. doi:10.1111/j.1574-6976.2008.00105.x * These authors have contributed equally to this work. |
Terrak, M. (2008). Peptidoglycan Glycosyltransferase Inhibition: New Perspectives for An Old Target. Anti-Infective Agents in Medicinal Chemistry. doi:10.2174/187152108784911241 |
Terrak, M., Sauvage, E., Derouaux, A., Dehareng, D., Bouhss, A., Breukink, E., Jeanjean, S., & Nguyen-Distèche, M. (2008). Importance of the conserved residues in the peptidoglycan glycosyltransferase module of the class A penicillin-binding protein 1b of Escherichia coli. Journal of Biological Chemistry, 283 (42), 28464-70. doi:10.1074/jbc.M803223200 |
Muller, P., Ewers, C., Bertsche, U., Anstett, M., Kallis, T., Breukink, E., Fraipont, C., Terrak, M., Nguyen-Distèche, M., & Vollmer, W. (14 December 2007). The essential cell division protein FtsN interacts with the murein (peptidoglycan) synthase PBP1B in Escherichia coli. Journal of Biological Chemistry, 282 (50), 36394-36402. doi:10.1074/jbc.M706390200 |
Terrak, M. (March 2007). Bacterial cell wall biosynthesis [Paper presentation]. The first international fungal/plant cell wall meeting: cell wall polysaccharides of fungi and plants, Biaritz, France. |
Terrak, M., & Nguyen-Distèche, M. (April 2006). Kinetic characterization of the monofunctional glycosyltransferase from Staphylococcus aureus. Journal of Bacteriology, 188 (7), 2528-2532. doi:10.1128/JB.188.7.2528-2532.2006 |
Zawadzka-Skomial, J., Markiewicz, Z., Nguyen-Distèche, M., Devreese, B., Frère, J.-M., & Terrak, M. (March 2006). Characterization of the bifunctional glycosyltransferase/acyltransferase penicillin-binding protein 4 of Listeria monocytogenes. Journal of Bacteriology, 188 (5), 1875-1881. doi:10.1128/JB.188.5.1875-1881.2006 |
Terrak, M., Rebowski, G., Lu, R. C., Grabarek, Z., & Dominguez, R. (2005). Structure of the light chain-binding domain of myosin V. Proceedings of the National Academy of Sciences of the United States of America, 102 (36), 12718-23. doi:10.1073/pnas.0503899102 |
Rebowski, Terrak, M., Lu, R. C., Dominguez, R., & Grabarek. (January 2004). The Iq motif defines the conformation of the interacting calmodullin. Biophysical Journal, 86, 571A-571. |
Terrak, M., Kerff, F., Langsetmo, K., Gong, B. J., Tao, T., & Dominguez, R. (2004). PP1 targeting and regulation as revealed by the structure of a PP1 delta-MYPT1 complex. Biophysical Journal, 86 (1), 172A-172. |
Terrak, M.* , Kerff, F.* , Langsetmo, K., Tao, T., & Dominguez, R. (2004). Structural basis of protein phosphatase 1 regulation. Nature, 429 (6993), 780-4. doi:10.1038/nature02582 * These authors have contributed equally to this work. |
Terrak, M., Staford, W., & Lu, R. (2004). The neck domain of myosin V. Biophysical Journal, 86, 572A-572. |
Terrak, M., Wu, G., Stafford, W. F., Lu, R. C., & Dominguez, R. (2003). Two distinct myosin light chain structures are induced by specific variations within the bound IQ motifs-functional implications. EMBO Journal, 22 (3), 362-71. doi:10.1093/emboj/cdg058 |
Terrak, M., Otterbein, L. R., Wu, G., Palecanda, L. A., Lu, R. C., & Dominguez, R. (2002). Crystallization, X-ray characterization and selenomethionine phasing of Mlc1p bound to IQ motifs from myosin V. Acta Crystallographica. Section D, Biological Crystallography, 58 (Pt 10 Pt 2), 1882-5. doi:10.1107/S0907444902013951 |
Terrak, M. (2000). Structure-function relationship of the Escherichia coli PBP1B modules [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/188950 |
Terrak, M., Ghosh, T. K., van Heijenoort, J., Van Beeumen, J., Lampilas, M., Aszodi, J., Ayala, J. A., Ghuysen, J.-M., & Nguyen-Distèche, M. (October 1999). The Catalytic, Glycosyl Transferase and Acyl Transferase Modules of the Cell Wall Peptidoglycan-Polymerizing Penicillin-Binding Protein 1b of Escherichia Coli. Molecular Microbiology, 34 (2), 350-364. doi:10.1046/j.1365-2958.1999.01612.x |
Goffin, C., Fraipont, C., Ayala, J., Terrak, M., Nguyen-Distèche, M., & Ghuysen, J.-M. (September 1996). The non-penicillin-binding module of the tripartite penicillin-binding protein 3 of Escherichia Coli is required for folding and/or stability of the penicillin-binding module and the membrane-anchoring module confers cell septation activity on the folded structure. Journal of Bacteriology, 178 (18), 5402-5409. doi:10.1128/jb.178.18.5402-5409.1996 |