Publications and communications of Sylvie Legrand

Iovino, M., Colonval, M., Wilkin, C., L'Homme, L., Lassence, C., Campas, M., Peulen, O., De Tullio, P., Piette, J., & Legrand, S. (2023). Novel XBP1s-independent function of IRE1 RNase in HIF-1α-mediated glycolysis upregulation in human macrophages upon stimulation with LPS or saturated fatty acid. Frontiers in Immunology. doi:10.3389/fimmu.2023.1204126

Wilkin, C., Colonval, M., Dehairs, J., Esser, N., Iovino, M., Gianfrancesco, M. A., FADEUR, M., Swinnen, J. V., PAQUOT, N., Piette, J., & Legrand, S. (2021). New insights on the PBMCs phospholipidome in obesity demonstrate modulations associated with insulin resistance and glycemic status. Nutrients. doi:10.3390/nu13103461

Iovino, M., Colonval, M., Paquot, N., & Legrand, S. (January 2019). Metabolic reprogramming of human monocytes/macrophages in obesity ; implications in obesity-linked inflammation and cancers [Poster presentation]. Télévie Cancer Seminar 2019.

Gianfrancesco, M., Paquot, N., Piette, J., & Legrand, S. (2018). Lipid bilayer stress in obesity-linked inflammatory and metabolic disorders. Biochemical Pharmacology. doi:10.1016/j.bcp.2018.02.022

Gianfrancesco, M., Dehairs, J., L’homme, L., Herinckx, G., Bloch, K., Piette, J., Rider, M., Swinnen, J., Paquot, N., Esser, N., & Legrand, S. (2018). La saturation des phospholipides membranaires induit un efflux de K+ et une activation de l’inflammasome NLRP3 dans des macrophages humains via l’intermédiaire de la Na, K-ATPase. Nutrition Clinique et Metabolisme, 32 (1), 38. doi:10.1016/j.nupar.2017.11.006

Gianfrancesco, M., Dehairs, J., Bloch, K., L’homme, L., Jansen, O., Frederich, M., Piette, J., Swinnen, J., Paquot, N., Esser, N., & Legrand, S. (2017). Implication du remodelage de la membrane plasmique par les acides gras dans la régulation de l’activité de l’inflammasome NLRP3 dans des macrophages humains. Nutrition Clinique et Metabolisme, 31 (3), 255. doi:10.1016/j.nupar.2017.06.002

TIMA, H. G., AL DULAYYMI, J. A. R., DENIS, O., LEHEBEL, P., BAOLS, K. S., MOHAMMED, M. O., L’HOMME, L., SAHB, M. M., POTEMBERG, G., Legrand, S., LANG, R., BEYAERT, R., PIETTE, J., BAIRD, M. S., HUYGEN, K.* , & ROMANO, M.*. (2016). Inflammatory properties and adjuvant potential of synthetic glycolipids homologous to mycolate esters of the cell wall of Mycobacterium tuberculosis. Journal of Innate Immunity. doi:10.1159/000450955

ESSER, N., Legrand-Poels, S., Piette, J., Paquot, N., & Scheen, A. (2014). Inflammasome NLRP3 et graisse viscerale. Revue Médicale de Liège, 69 Spec No, 57-61.

ESSER, N., Legrand, S., Piette, J., SCHEEN, A., & PAQUOT, N. (2014). Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes. Diabetes Research and Clinical Practice. doi:10.1016/j.diabres.2014.04.006

ESSER, N., L'Homme, L., DE ROOVER, A., KOHNEN, L., SCHEEN, A., MOUTSCHEN, M., Piette, J., Legrand-Poels, S., & PAQUOT, N. (November 2013). Obesity phenotype is related to NLRP3 inflammasome activity and immunological profile of visceral adipose tissue. Diabetologia, 56, 2487-2497. doi:10.1007/s00125-013-3023-9

Esser, N., L'Homme, L., DE ROOVER, A., KOHNEN, L., SCHEEN, A., MOUTSCHEN, M., Piette, J., Legrand-Poels, S., & PAQUOT, N. (2013). Increased Inflammasome and Caspase-1 Activation in Visceral adipose tissue from Metabolically Unhealthy Obese compared to Metabolically Healthy Obese subjects. Diabetes, (62/suppl.1), 555.

Esser, N., L'Homme, L., DE ROOVER, A., KOHNEN, L., SCHEEN, A., Moutschen, M., Piette, J., Legrand-Poels, S., & PAQUOT, N. (March 2013). Différences d’activité de l’inflammasome NLRP3 entre sujets obèses avec et sans anomalies métaboliques. Diabetes and Metabolism, 39 (suppl 1), 102.

Esser, N., L'Homme, L., SCHEEN, A., MOUTSCHEN, M., Piette, J., PAQUOT, N., & Legrand, S. (January 2013). Differences in inflammasome activation between metabolically healthy and unhealthy obese individuals [Poster presentation]. Metabolic control of inflammation and immunity, Breckenridge, Colorado, United States.

L'Homme, L., Esser, N., PAQUOT, N., Piette, J., & Legrand, S. (January 2013). Unsaturated fatty acids inhibit saturated fatty acids-induced NLRP3 inflammasome activation [Poster presentation]. Keystone Symposia meeting on "Metabolic Control of Inflammation and Immunity", Breckenridge, Colorado, United States.

Condé, C., Rambout, X., Lebrun, M., Lecat, A., Di Valentin, E., Dequiedt, F., Piette, J., Gloire, G., & Legrand, S. (2012). The inositol phosphatase SHIP-1 inhibits NOD2-induced NF-κB activation by disturbing the interaction of XIAP with RIP2. PLoS ONE. doi:10.1371/journal.pone.0041005

Lecat, A., Piette, J., & Legrand-Poels, S. (2010). The protein Nod2: an innate receptor more complex than previously assumed. Biochemical Pharmacology, 80 (12), 2021-31. doi:10.1016/j.bcp.2010.07.016

Legrand, S., Kustermans, G., Bex, F., Kufer, T., Kremmer, E., & Piette, J. (01 April 2007). Modulation of Nod2-dependent NF-kappa B signaling by the actin cytoskeleton. Journal of Cell Science, 120 (7), 1299-1310. doi:10.1242/jcs.03424

Gloire, G., Legrand-Poels, S., & Piette, J. (30 November 2006). NF-kappa B activation by reactive oxygen species: Fifteen years later. Biochemical Pharmacology, 72 (11), 1493-1505. doi:10.1016/j.bcp.2006.04.011

JOSSE, C., Legrand-Poels, S., Piret, B., Sluse, F., & Piette, J. (1998). Impairment of the mitochondrial electron chain transport prevents NF-kappa B activation by hydrogen peroxide. Free Radical Biology and Medicine, 25 (1), 104-112. doi:10.1016/S0891-5849(98)00057-4

Legrand-Poels, S., Bours, V., Piret, B., Pflaum, M., Epe, B., Rentier, B., & Piette, J. (24 March 1995). Transcription factor NF-kB is activated by photosensitization generating oxidative DNA damages. Journal of Biological Chemistry, 270 (12), 6925-6934. doi:10.1074/jbc.270.12.6925

Legrand, S., Hoebeke, M., Vaira, D., Rentier, B., & Piette, J. (March 1993). HIV-1 promoter activation following an oxidative stress mediated by singlet oxygen. Journal of Photochemistry and Photobiology B: Biology, 17 (3), 229-237. doi:10.1016/1011-1344(93)80020-A