Publications and communications of Marianne Fillet

Boclinville, A., Vandevenne, M., Ambroggio, E., Thelen, N., Thiry, M., Jacobs, N., Brans, A., Fillet, M., & Servais, A.-C. (April 2024). Interaction studies between human papillomavirus virus-like particles and laminin 332 by affinity capillary electrophoresis assisted by bio-layer interferometry. Talanta, 270, 125602. doi:10.1016/j.talanta.2023.125602

Gou, M.-J., Cobraiville, G., Caers, J., & Fillet, M. (28 February 2024). Capillary electrophoresis coupled to ion mobility mass spectrometry to discover surface antigens [Paper presentation]. CE-Forum, Aalen, Germany.

Faville, C.* , E Silva, B.* , Jassin, M., DUBOIS, S., Daulne, C., Cobraiville, G., De Voeght, A., Baron, F., Fillet, M.* , & Ehx, G.*. (06 February 2024). Discovery And Targeting of Persister-specific Antigens in Acute Myeloid Leukemia [Poster presentation]. Télévie Seminar.

Faville, C.* , E Silva, B.* , Jassin, M., DUBOIS, S., Daulne, C., Cobraiville, G., De Voeght, A., Baron, F., Fillet, M.* , & Ehx, G.*. (06 February 2024). Discovery And Targeting of Persister-specific Antigens in Acute Myeloid Leukemia [Paper presentation]. Télévie Seminar.

Davoine, C., Pochet Lionel, & Fillet, M. (31 January 2024). Fragment screening and binding site characterization using affinity capillary electrophoresis in the context of drug discovery [Paper presentation]. CIRM Day, Liege, Belgium.

Fillet, M. (25 January 2024). L’électrophorèse capillaire, une technique séparative fiable et pourtant négligée. Exemples d’applications soulignant les points à considérer pour son utilisation raisonnée [Paper presentation]. AFSEP, Lyon, France.

Nix, C., Sulejman, S., Cobraiville, G., Njock, M.-S., Paulissen, G., de Seny, D., & Fillet, M. (2024). Development of complementary analytical methods to characterize extracellular vesicles [Paper presentation]. CIRM Day, Liege, Belgium.

Fillet, M. (01 December 2023). State of the art of lipidomics workflows for the analysis of biological samples by mass spectrometry VUB lipidomics [Paper presentation]. Minisymposium on -omics approaches, Bruxelles, Belgium.

Davoine, C., Traina, A., Evrard, J., Lanners, S., Fillet, M., & Pochet, L. (05 November 2023). Coumarins as factor XIIa inhibitors: Potency and selectivity improvements using a fragment-based strategy. European Journal of Medicinal Chemistry, 259, 115636. doi:10.1016/j.ejmech.2023.115636

Davoine, C., Pochet, L., & Fillet, M. (27 October 2023). Activity and affinity assays by capillary electrophoresis in the context of drug screening [Paper presentation]. Jinan University, Guangzhou, China.

Villard, A., Goïta, A., Fillet, M., & Gilles, C. (27 October 2023). TF/FVIIa-mediated shedding of CD44 in EMT-shifted human breast tumor cells [Poster presentation]. BACR 2023, Bruxelles, Belgium.

Pierson, E., De Pol, F., Fillet, M., & Wouters, J. (10 October 2023). A morpheein equilibrium regulates catalysis in phosphoserine phosphatase SerB2 from Mycobacterium tuberculosis. Communications Biology, 6 (1), 1024. doi:10.1038/s42003-023-05402-z

Gou, M.-J., Charpentier, J., Cobraiville, G., Crommen, J., Caers, J., & Fillet, M. (October 2023). Improvement of untargeted proteomics workflow for surfaceome profiling and its evaluation through the implementation of quality controls: Application to multiple myeloma. Analytica Chimica Acta, 1279, 341764. doi:10.1016/j.aca.2023.341764

Davoine, C., Pochet, L., & Fillet, M. (28 September 2023). Intérêt de l’EC dans le contexte du développement de médicaments pour le screening de ligands et la caractérisation de leur interaction avec la cible thérapeutique [Paper presentation]. Conférence « La Chimie Analytique au service de la Santé », Geneve, Switzerland.

Kumari, P., Van Laethem, T., Duroux, D., Fillet, M., Hubert, P., Sacre, P.-Y., & Hubert, C. (04 September 2023). A multi-target QSRR approach to model retention times of small molecules in RPLC. Journal of Pharmaceutical and Biomedical Analysis, 236, 115690. doi:10.1016/j.jpba.2023.115690

Davoine, C., Pochet, L., & Fillet, M. (September 2023). Advances in analytical technologies detecting and characterizing noncovalent interactions for fragment-based drug discovery. TrAC: Trends in Analytical Chemistry, 166, 117161. doi:10.1016/j.trac.2023.117161

Gallez, A., Nys, G., Wuidar, V., Dias Da Silva, I., Taziaux, M., Kinet, V., Tskitishvili, E., Noël, A., Foidart, J.-M., Piel, G., Fillet, M., & Pequeux, C. (03 June 2023). Comparison of Estetrol Exposure between Women and Mice to Model Preclinical Experiments and Anticipate Human Treatment. International Journal of Molecular Sciences, 24 (11), 9718. doi:10.3390/ijms24119718

Fillet, M. (02 June 2023). Contribution of capillary electrophoresis in the context of drug development and quality control [Paper presentation]. CIP, Liege, Belgium.

Laurent, A., Nix, C.* , Cobraiville, G., Crommen, J., & Fillet, M. (2023). A targeted UHPLC-MS/MS method to monitor lipidomic changes during a physical effort: Optimzation and application to blood microsamples from athletes. Journal of Pharmaceutical and Biomedical Analysis. doi:10.1016/j.jpba.2023.115373

Laurent, A.* , Nix, C.* , Cobraiville, G., Crommen, J., & Fillet, M. (30 May 2023). A targeted UHPLC-MS/MS method to monitor lipidomic changes during a physical effort: Optimization and application to blood microsamples from athletes. Journal of Pharmaceutical and Biomedical Analysis, 229, 115373. doi:10.1016/j.jpba.2023.115373

Nix, C., Ciregia Frederica, Cobraiville, G., de Seny, D., & Fillet, M. (24 May 2023). Microfluidic liquid chromatography coupled to drift-tube ion mobility and high-resolution mass spectrometry for the analysis of fibroblast-like synoviocytes stimulated with SAA variants [Paper presentation]. 39th International Symposium on Microscale Separation and Bioanalysis (MSB), Tallahassee, United States.

PIERSON, E., Nix, C., Wouters, J., & Fillet, M. (24 May 2023). Identification of a morpheein - like behavior of a phosphoserine phosphatase through biophysical characterization of its oligomerization states [Poster presentation]. 39th International Symposium on Microscale Separation and Bioanalysis (MSB), Tallahassee, United States.

Fillet, M. (28 March 2023). Suivi des interactions protéine-ligand et protéine-protéine par électrophorèse capillaire dans le contexte du développement de médicaments [Paper presentation]. AFSEP, Paris, France.

Ghasemi Kakroodi, M., & Fillet, M. (28 March 2023). Improvement of chemo- and stereoselectivity for phosphorothioate oligonucleotides in capillary electrophoresis using cyclodextrins [Paper presentation]. AFSEP, Paris, France.

Kumari, P., Van Laethem, T., Hubert, P., Fillet, M., Sacre, P.-Y., & Hubert, C. (10 February 2023). Quantitative Structure Retention-Relationship Modeling: Towards an Innovative General-Purpose Strategy. Molecules, 28 (4), 1696. doi:10.3390/molecules28041696

Charpentier, J., Gou, M.-J., Caers, J., KOSE Murat Cem, & Fillet, M. (01 February 2023). Multiple myeloma cells surface proteomics using microfluidic reverse phase liquid chromatography coupled to drift tube ion mobility quadrupole time-of-flight: optimization of sample preparation protocol and application to patient samples [Paper presentation]. CIRM Day, Liege, Belgium.

Ghasemi Kakroodi, M., & Fillet, M. (01 February 2023). Application of cyclodextrins in capillary electrophoresis to improve stereo- and chemo selectivity of phosphorothioate oligonucleotides [Paper presentation]. CIRM Day, Liege, Belgium.

Gou, M.-J., Köse, M. C., Nix, C., Cobraiville, G., Caers, J., & Fillet, M. (01 February 2023). Complementarity of CZE-DTIMS-QTOF to microfluidic-RPLC-DTIMS-QTOF for multiple myeloma cells surface antigen discovery [Paper presentation]. CIRM Day, Liège, Belgium.

Nix, C., Ciregia, F., Cobraiville, G., de Seny, D., & Fillet, M. (01 February 2023). Micropillar array column coupled to drift-tube ion mobility and mass spectrometry for the analysis of fibroblast-like synoviocytes [Paper presentation]. CIRM Day, Liege, Belgium.

Priyanka Kumari, Van Laethem, T., Hubert, P., Fillet, M., Sacre, P.-Y., & Hubert, C. (01 February 2023). A multi-target QSRR(mT-QSRR) approach to model retention time of small pharmaceutical compounds in RPLC [Paper presentation]. CIRM DAY 2023, Liege, Belgium.

Lejeune, M., Köse, M. C., Jassin, M., Gou, M.-J., Herbet, A., Duray, E., Cobraiville, G., FOGUENNE, J., Boquet, D., Gothot, A., Beguin, Y., Fillet, M., & Caers, J. (2023). Integrative Analysis of Proteomics and Transcriptomics Reveals Endothelin Receptor B as Novel Single Target and Identifies New Combinatorial Targets for Multiple Myeloma. HemaSphere, 22, 901. doi:10.1097/HS9.0000000000000901

Schmitz, L., Pirotte, M., Lebeau, A., Ernst, M., Fillet, M., DEVEY, A., SCHMITT, J., Cobraiville, G., BINSFELD, M., Gofflot, S., Beguin, Y.* , & Vertenoeil, G.*. (2023). Alterations of erythropoiesis in Covid-19 patients: prevalence of positive Coombs tests and iron metabolism. Therapeutic Advances in Hematology, 14, 20406207231199837. doi:10.1177/20406207231199837

Van Laethem, T., Kumari, P., Boulanger, B., Hubert, P., Fillet, M., Sacre, P.-Y., & Hubert, C. (28 November 2022). User-Driven Strategy for In Silico Screening of Reversed-Phase Liquid Chromatography Conditions for Known Pharmaceutical-Related Small Molecules. Molecules, 27 (23), 8306. doi:10.3390/molecules27238306

Köse, M. C., Lejeune, M., Gou, M.-J., Duray, E., Cobraiville, G., Gothot, A., Beguin, Y., Fillet, M., & Caers, J. (15 November 2022). Integrative Analysis of Proteomics and Transcriptomics Reveals the Etrb As Novel Single Target and New Combinatorial Targets for Multiple Myeloma [Paper presentation]. ASH 2022 Symposium, New orleans, United States.

Villard, A., Özsoy, B., Fillet, M., & Gilles, C. (07 November 2022). TF/FVIIa-mediated shedding of CD44 in EMT-shifted human breast tumor cells [Poster presentation]. TEMTIA X Congress, Paris, France.

Villard, A., Özsoy, B., Fillet, M., & Gilles, C. (07 November 2022). TF/FVIIa-mediated shedding of CD44 in EMT-shifted human breast tumor cells [Paper presentation]. TEMTIA X Congress, Paris, France.

Farre Segura, J., Le Goff, C., LUKAS, P., Cobraiville, G., Fillet, M., Servais, A.-C., Delanaye, P., & Cavalier, E. (03 November 2022). Validation of an LC-MS/MS Method Using Solid-Phase Extraction for the Quantification of 1-84 Parathyroid Hormone: Toward a Candidate Reference Measurement Procedure. Clinical Chemistry, 68 (11), 1399-1409. doi:10.1093/clinchem/hvac135

Gou, M.-J., Köse, M. C., Crommen, J., Nix, C., Cobraiville, G., Caers, J., & Fillet, M. (01 November 2022). Contribution of Capillary Zone Electrophoresis Hyphenated with Drift Tube Ion Mobility Mass Spectrometry as a Complementary Tool to Microfluidic Reversed Phase Liquid Chromatography for Antigen Discovery. International Journal of Molecular Sciences, 23 (21), 13350. doi:10.3390/ijms232113350

Nix, C.* , Ghassemi, M.* , Crommen, J., & Fillet, M. (October 2022). Overview on microfluidics devices for monitoring brain disorder biomarkers. TrAC: Trends in Analytical Chemistry, 155, 116693. doi:10.1016/j.trac.2022.116693

Boclinville, A., Ambroggio, E., Brans, A., Thelen, N., Thiry, M., Jacobs, N., Fillet, M., & Servais, A.-C. (28 September 2022). Analytical strategies for the study of HPV / host cell receptors interactions [Paper presentation]. 14e journée de l'AFIPP, Sedan, France.

Gou, M.-J., Köse, M. C., Cobraiville, G., Caers, J., & Fillet, M. (13 September 2022). Use of CE-IM-MS as a complementary tool to microfluidic-LC-IM-MS for cell surface antigen discovery [Paper presentation]. 39th International Symposium of Pharmaceutical and Biomedical analysis (PBA), Mons, Belgium.

Boclinville, A., Ambroggio, E., Brans, A., Thelen, N., Thiry, M., Jacobs, N., Fillet, M., & Servais, A.-C. (11 September 2022). Investigation of the interaction between HPV and host cell receptor by affinity capillary electrophoresis and bio-layer interferometry [Paper presentation]. 12th International Symposium on Drug Analysis and 32nd International Symposium on Pharmaceutical and Biomedical Analysis, Mons, Belgium.

Davoine, C., Pochet, L., & Fillet, M. (11 September 2022). Affinity Capillary Electrophoresis for Fragment-based Drug Discovery Projects: Hit Discovery and Binding Site Characterization [Paper presentation]. 12th International Symposium on Drug Analysis and the 32nd International Symposium on Pharmaceutical and Biomedical Analysis (DA-PBA 2022), Mons, Belgium.

Lu, L., Liu, X., Zuo, C., Zhou, J., Zhu, C., Zhang, Z., Fillet, M., Crommen, J., Jiang, Z., & Wang, Q. (08 September 2022). In vitro/in vivo degradation analysis of trastuzumab by combining specific capture on HER2 mimotope peptide modified material and LC-QTOF-MS. Analytica Chimica Acta, 1225, 340199. doi:10.1016/j.aca.2022.340199

Ghassemi K, M., Demelenne, A., Crommen, J., Servais, A.-C., & Fillet, M. (02 August 2022). Improvement of chemo- and stereoselectivity for phosphorothioate oligonucleotides in capillary electrophoresis by addition of cyclodextrins. Journal of Chromatography. A, 1676, 463270. doi:10.1016/j.chroma.2022.463270

Nyssen, L., Fillet, M., Cavalier, E., & Servais, A.-C. (14 July 2022). Qualitative and quantitative comparison of different commercially available 1-84 parathyroid hormone proteins to the WHO international standard 95/646 using orthogonal methods. Journal of Pharmaceutical and Biomedical Analysis, 219, 114942. doi:10.1016/j.jpba.2022.114942

Gou, M.-J., Cobraiville, G., Nys, G., Caers, J., & Fillet, M. (06 July 2022). Interest of capillary zone electrophoresis coupled to mass spectrometry for clinical proteomics analysis : how to improve sensitivity? [Paper presentation]. 38th International Symposium on Microscale Separations and Bioanalysis, Liège, Belgium.

Nix, C., Cobraiville, G., Gou, M.-J., & Fillet, M. (06 July 2022). Potential of Single Pulse and Multiplexed Drift-Tube Ion Mobility Spectrometry Coupled to Micropillar Array Column for Proteomics Studies. International Journal of Molecular Sciences, 23 (14), 7497. doi:10.3390/ijms23147497

Kumari, P., Van Laethem, T., Hubert, P., Fillet, M., Sacre, P.-Y., & Hubert, C. (04 July 2022). QSRR for small pharmaceutical compounds in RPLC: A Machine learning approach [Paper presentation]. 18th Chemometrics in Analytical Chemistry Conference, Rome, Italy.

Boclinville, A., Jacobs, N., Thelen, N., Thiry, M., Fillet, M., & Servais, A.-C. (03 July 2022). Interaction studies between HPV and host cell receptor by affinity capillary electrophoresis [Poster presentation]. 38th International Symposium on Microscale Separations and Bioanalysis.

Davoine, C., Pochet, L., & Fillet, M. (03 July 2022). Affinity Capillary Electrophoresis in Fragment-based Drug Discovery Projects, A tool for Hit discovery and Binding site Characterization [Paper presentation]. 38th International Symposium on Microscale Separations and Bioanalysis (MSB 2022), Liège, Belgium.

Gou, M.-J., Cobraiville, G., Caers, J., & Fillet, M. (03 July 2022). Interest of CE-IM-MS as a complementary tool to chromatographic-based methods for cell surface antigen discovery: proof-of-concept using human myeloma LP-1 cell line [Poster presentation]. 38th International Symposium on Microscale Separations and Bioanalysis (MSB 2022), Liège, Belgium.

Dispas, A., Emonts, P., Vandormael Denis, Bernier Damien, Dortu Fabian, Ziemons, E., Hubert, P., & Fillet, M. (July 2022). Hydrodynamic injection for microchip electrophoresis: development of an innovative prototype [Poster presentation]. MSB2022.

Van Laethem, T., Kumari, P., Hubert, P., Fillet, M., Sacre, P.-Y., & Hubert, C. (June 2022). A pharmaceutical-related molecules dataset for reversed-phase chromatography retention time prediction built on combining pH and gradient time conditions. Data in Brief, 42, 108017. doi:10.1016/j.dib.2022.108017

Davoine, C., Fillet, M., & Pochet, L. (19 May 2022). Discovery of Potent FXIIa Inhibitors using a Fragment-based Strategy [Paper presentation]. FNRS Med Chem Meeting, Namur, Belgium.

Van Laethem, T., Kumari, P., Fillet, M., Hubert, P., Hubert, C., & Sacre, P.-Y. (18 May 2022). In-silico screening for the development of robust reversed-phase liquid chromatography methods of known small molecules based on QSRR and desirability index [Paper presentation]. 17th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology (HTC-17), Gent, Belgium.

Farre Segura, J., COBRAIVILLE, G., LUKAS, P., LE GOFF, C., Servais, A.-C., Fillet, M., DELANAYE, P., & CAVALIER, E. (11 April 2022). Development and validation of a candidate reference method for 1-84 PTH by LC-MS/MS [Poster presentation]. EuroMedLab 2021 Munich, Munich, Germany.

Coic, L., Sacre, P.-Y., Dispas, A., De Bleye, C., Fillet, M., Ruckebusch, C., Hubert, P., & Ziemons, E. (March 2022). Selection of essential spectra to improve the multivariate curve resolution of minor compounds in complex pharmaceutical formulations. Analytica Chimica Acta, 1198, 339532. doi:10.1016/j.aca.2022.339532

Lebeau, A.* , Bruyère, D.* , RONCARATI, P., Peixoto, P., Hervouet, E., COBRAIVILLE, G., Taminiau, B., Masson, M., Gallego, C., Mazzucchelli, G., Smargiasso, N., Fleron, M., Baiwir, D., Hendrick, E., Pilard, C., Lerho, T., Reynders, C., Ancion, M., GREIMERS, R., ... Herfs, M. (28 February 2022). HPV infection alters vaginal microbiome through down-regulating host mucosal innate peptides used by Lactobacilli as amino acid sources. Nature Communications, 13 (1), 1076. doi:10.1038/s41467-022-28724-8

Boclinville, A., Jacobs, N., Thelen, N., Thiry, M., Fillet, M., & Servais, A.-C. (02 February 2022). Interaction studies between HPV-VLP and laminin 332 receptor by affinity capillary electrophoresis [Poster presentation]. CIRM Day 2022.

Davoine, C., Pochet, L., & Fillet, M. (02 February 2022). Development of Factor XIIa Inhibitors Assisted by Affinity Capillary Electrophoresis, A Fragment-based Lead Discovery Project [Paper presentation]. CIRM day 2022, Liège, Belgium.

Faville, C., Nix, C., Baron, F., Ehx, G., & Fillet, M. (02 February 2022). Discovery of tumor-specific antigens presented by diapaused acute myeloid leukemia (AML) cells using ion-mobility mass spectrometry [Paper presentation]. CIRM-Day.

Gou, M.-J., COBRAIVILLE, G., CAERS, J., & Fillet, M. (02 February 2022). Optimization of OPM-2 cell surface protein isolation process for multiple myeloma proteomics using LC-Chip coupled with IM-QTOF [Poster presentation]. 4th CIRM Day, Liege, Belgium.

Van Laethem, T., Kumari, P., Fillet, M., Hubert, P., Hubert, C., & Sacre, P.-Y. (02 February 2022). Elaboration of a strategy for in silico screening for reversed-phase liquid chromatography method development [Paper presentation]. CIRM-day 2022, Liège, Belgium.

Demelenne, A., Nys, G., Nix, C., Fjeldsted, J. C., Crommen, J., & Fillet, M. (25 January 2022). Separation of phosphorothioated oligonucleotide diastereomers using multiplexed drift tube ion mobility mass spectrometry. Analytica Chimica Acta, 1191, 339297. doi:10.1016/j.aca.2021.339297

Nix, C., & Fillet, M. (2022). Chapter 10-Microfluidics in three key aspects of the drug-development process: biomarker discovery, preclinical studies and drug delivery systems. In Multidisciplinary Microfluidic and Nanofluidic Lab-on-a-chip (pp. 275-295). Elsevier. doi:10.1016/B978-0-444-59432-7.00017-0

Davoine, C., Pardo, A., Pochet, L., & Fillet, M. (09 November 2021). Fragment Hit Discovery and Binding Site Characterization by Indirect Affinity Capillary Electrophoresis: Application to Factor XIIa. Analytical Chemistry, 93, 14802–14809. doi:10.1021/acs.analchem.1c03611

Van Laethem, T., Kumari, P., Fillet, M., Hubert, P., Hubert, C., & Sacre, P.-Y. (05 October 2021). Modélisation du temps de rétention de petites molécules pharmaceutiques en chromatographie liquide en phase inverse basée sur le QSRR et les surfaces de réponse [Poster presentation]. 14ème Congrès Francophone sur les Sciences Séparatives et les Couplages de l'AFSEP, Paris, France.

Emonts, P., Avohou, T. H., Hubert, P., Ziemons, E., Fillet, M., & Dispas, A. (October 2021). Optimization of a robust and reliable FITC labeling process for CE-LIF analysis of pharmaceutical compounds using design of experiments strategy. Journal of Pharmaceutical and Biomedical Analysis, 205, 114304. doi:10.1016/j.jpba.2021.114304

Emonts, P., Avohou, T. H., Hubert, P., Ziemons, E., Fillet, M., & Dispas, A. (October 2021). Development of a sensitive MEKC-LIF method for the analysis of synthetic cathinones and amphetamines Paul Emonts [Poster presentation]. SEP2021, Paris, France.

Davoine, C., Simon, F., Bouckaert, C., Fillet, M., & Pochet, L. (09 September 2021). Using Biochemical Assay and Capillary Electrophoresis to Explore Fragments against Coagulation Factor XIIa [Poster presentation]. 8th EFMC Young Medicinal Chemists' Symposium.

Demelenne, A., Servais, A.-C., Crommen, J., & Fillet, M. (16 August 2021). Analytical techniques currently used in the pharmaceutical industry for the quality control of RNA-based therapeutics and ongoing developments. Journal of Chromatography. A, 1651, 462283. doi:10.1016/j.chroma.2021.462283

CIREGIA, F., Nys, G., Cobraiville, G., Badot, V., Di Romana, S., Sidiras, P., Sokolova, T., Durez, P., Fillet, M., Malaise, M., & de Seny, D. (2021). A Cross-Sectional and Longitudinal Study to Define Alarmins and A-SAA Variants as Companion Markers in Early Rheumatoid Arthritis. Frontiers in Immunology. doi:10.3389/fimmu.2021.638814

Ilangala Booka, A., Lechanteur, A., Fillet, M., & Piel, G. (2021). Therapeutic peptides for chemotherapy: trends and challenges for advanced delivery systems. European Journal of Pharmaceutics and Biopharmaceutics. doi:10.1016/j.ejpb.2021.07.010

Kumari, P., Van Laethem, T., Hubert, P., Fillet, M., Hubert, C., & Sacre, P.-Y. (22 July 2021). A QSRR modelling of small pharmaceutical compounds in Reverse Phase Liquid Chromatography [Paper presentation]. MLSS 2021 TAIPEI (Machine Learning Summer School), TAIPEI, Taiwan.

Gou, M.-J., COBRAIVILLE, G., CAERS, J., & Fillet, M. (12 July 2021). Multiple myeloma cells surface proteome analysis using LC-Chip coupled with IM-qTOF: optimization of cell surface protein isolation procedure [Poster presentation]. 37th International Symposium on Microscale Separation and Bioanalysis, Boston, United States.

Nyssen, L., Fillet, M., CAVALIER, E., & Servais, A.-C. (July 2021). Analytical strategies for the quality control of parathyroid hormone standards [Poster presentation]. 37th International Symposium on Microscale Separations and Bioanalysis - Virtual edition, Boston, United States - Massachusetts.

Dispas, A., Emonts, P., & Fillet, M. (June 2021). Microchip electrophoresis: A suitable analytical technique for pharmaceuticals quality control ? A critical review. TrAC: Trends in Analytical Chemistry, 139, 116226. doi:10.1016/j.trac.2021.116266

Davoine, C., Simon, F., Lanners, S., Fillet, M., & Pochet, L. (28 May 2021). Exploring Fragments to Design FXIIa Inhibitors with Biochemical Assay and Capillary Electrophoresis [Paper presentation]. FNRS Med Chem Meeting.

Davoine, C., Fillet, M., & Pochet, L. (26 May 2021). Uncovering biochemical assay’s false positives by counter-screening a fragment library with affinity capillary electrophoresis [Poster presentation]. CIRM-day 2021.

Van Laethem, T., Kumari, P., Hubert, P., Fillet, M., Hubert, C., & Sacre, P.-Y. (24 May 2021). Adaptive response surface model of small pharmaceutical compounds in reverse phase liquid chromatography [Paper presentation]. CIRM-day 2021, Liège, Belgium.

Davoine, C., Fillet, M., & Pochet, L. (01 May 2021). Capillary electrophoresis as a fragment screening tool to cross-validate hits from chromogenic assay: Application to FXIIa. Talanta, 226. doi:10.1016/j.talanta.2021.122163

Coic, L., Sacre, P.-Y., Dispas, A., De Bleye, C., Fillet, M., Ruckebusch, C., Hubert, P., & Ziemons, E. (22 April 2021). Pixel-based Raman hyperspectral identification of complex pharmaceutical formulations. Analytica Chimica Acta, 1155, 338361. doi:10.1016/j.aca.2021.338361

Kumari, P., Van Laethem, T., Hubert, P., Fillet, M., Hubert, C., & Sacre, P.-Y. (03 February 2021). Quantitative structure-retention relationship modelling of small pharmaceutical compounds in reverse phase liquid chromatography [Paper presentation]. e-CHIMIOMETRIE 2021.

Kumari, P., Van Laethem, T., Hubert, P., Fillet, M., Hubert, C., & Sacre, P.-Y. (03 February 2021). Quantitative structure-retention relationship modelling of small pharmaceutical compounds in reverse phase liquid chromatography [Paper presentation]. Chimiométrie.

Ciregia, F., DEROYER, C., COBRAIVILLE, G., PLENER, Z., MALAISE, O., GILLET, P., Fillet, M., MALAISE, M., & DE SENY, D. (2021). Modulation of αVβ6 integrin in osteoarthritis-related synovitis and the interaction with VTN (381-397 a.a.) competing for TGF-β1 activation. Experimental and Molecular Medicine. doi:10.1038/s12276-021-00558-2

Coic, L., Sacre, P.-Y., Dispas, A., De Bleye, C., Fillet, M., Ruckebusch, C., Hubert, P., & Ziemons, E. (February 2021). Pixel-based identification of Raman hyperspectral data: application to pharmaceutical tablets impurities detection [Paper presentation]. e-Chimiométrie 2021.

Buscato, M., Davezac, M., Zahreddine, R., Adlanmerini, M., Métivier, R., Fillet, M., COBRAIVILLE, G., Moro, C., Foidart, J.-M., Lenfant, F., Gourdy, P., Amal, J.-F., & Fontaine, C. (2021). Estetrol prevents western diet-induced obesity and atheroma independently of hepatic estrogen receptor (ER)α. American Journal of Physiology - Endocrinology and Metabolism, 320. doi:10.1152/ajpendo.00211.2020

de Bournonville, M.-P., de Bournonville, C., Vandries, L., Nys, G., Fillet, M., Ball, G., Balthazart, J., & Cornil, C. (2021). Rapid changes in brain estrogen concentration during male sexual behavior are site and stimulus specific. Scientific Reports, 11 (1), 20130. doi:10.1038/s41598-021-99497-1

Delage, C., Nys, G., Fillet, M., & Cornil, C. (2021). Effect of cyclo-oxygenase inhibition on embryonic microglia and the sexual differentiation of the brain and behavior of Japanese quail (Coturnix japonica). Hormones and Behavior, 134, 105024. doi:10.1016/j.yhbeh.2021.105024

Demelenne, A., Ben Yahia, A., Lempereur, D., Crommen, J., Servais, A.-C., Fradi, I., & Fillet, M. (2021). Comparison of Three Complementary Analytical Techniques for the Evaluation of the Biosimilar Comparability of a Monoclonal Antibody and an Fc-Fusion Protein. Frontiers in Chemistry, 9, 782099. doi:10.3389/fchem.2021.782099

Emonts, P., Servais, A.-C., Ziemons, E., Hubert, P., Fillet, M., & Dispas, A. (January 2021). Development of a sensitive MEKC‐LIF method for synthetic cathinones analysis. Electrophoresis, 0, 1-8. doi:10.1002/elps.202000331

Kumari, P., Van Laethem, T., Hubert, P., Fillet, M., Sacre, P.-Y., & Hubert, C. (2021). QSRR modelling of small pharmaceutical compounds in Liquid Chromatography [Paper presentation]. Summer Research internship, Milan, Italy.

Nix, C., & Fillet, M. (2021). The promise of blood microsampling in pre-clinical and clinical studies [Paper presentation]. Journée scientifique du club Ile-de-France de l'AFSEP.

Nix, C., Hemmati, M., COBRAIVILLE, G., Servais, A.-C., & Fillet, M. (2021). Potential of hemaPEN microsampling devices to monitor training load and health of sport practitioners using a targeted metabolomics approach [Poster presentation]. 37th International Symposium on Microscale Separation and Bioanalysis.

Nix, C., Hemmati, M., COBRAIVILLE, G., Servais, A.-C., & Fillet, M. (2021). Fluxomics analysis on blood microsampling for metabolites monitoring during sport [Poster presentation]. Thrid CIRM day.

Nix, C., Hemmati, M., COBRAIVILLE, G., Servais, A.-C., & Fillet, M. (2021). Blood Microsampling to Monitor Metabolic Profiles During Physical Exercise. Frontiers in Molecular Biosciences. doi:10.3389/fmolb.2021.681400

PIROTTE, M., Fillet, M., SEIDEL, L., JASPERS, A., Baron, F., & Beguin, Y. (2021). Erythroferrone and hepcidin as mediators between erythropoiesis and iron metabolism during allogeneic hematopoietic stem cell transplant. American Journal of Hematology, 96 (10), 1275-1286. doi:10.1002/ajh.26300

Davoine, C., Bouckaert, C., Fillet, M., & Pochet, L. (15 December 2020). Factor XII/XIIa inhibitors: Their discovery, development, and potential indications. European Journal of Medicinal Chemistry, 208. doi:10.1016/j.ejmech.2020.112753

CIREGIA, F., Nys, G., COBRAIVILLE, G., Badot, V., Di Romana, S., Sidiras, P., Sokolova, T., Durez, P., Fillet, M., Malaise, M., & DE SENY, D. (December 2020). Caractérisation de l’expression des alarmines et des variants A-SAA dans la polyarthrite rhumatoïde débutante. Revue du Rhumatisme, 87 (S1), 126. doi:10.1016/j.rhum.2020.10.218

Gou, M.-J., Nys, G., COBRAIVILLE, G., Demelenne, A., Servais, A.-C., CAERS, J., & Fillet, M. (30 September 2020). CE-MS/MS: investigation of two hyphenating approaches for proteomics studies in the context of multiple myeloma [Paper presentation]. 36th International Symposium on Microscale Separations and Bioanalysis, Saint-Malo, France.

Drouin, N., Van Mever, M., Zhang, W., Tobolkina, E., Ferre, S., Servais, A.-C., Gou, M.-J., Nyssen, L., Fillet, M., Lageveen-Kammeijer, G. S. M., Nouta, J., Chetwynd, A. J., Lynch, I., Thorn, J. A., Meixner, J., Lössner, C., Taverna, M., Liu, S., Tran, N. T., ... Ramautar, R. (22 September 2020). Capillary Electrophoresis-Mass Spectrometry at Trial by Metabo-Ring: Effective Electrophoretic Mobility for Reproducible and Robust Compound Annotation. Analytical Chemistry, 92 (20), 14103-14112. doi:10.1021/acs.analchem.0c03129

Emonts, P., Dispas, A., Fillet, M., & Servais, A.-C. (Other coll.). (September 2020). Development of a sensitive MEKC-LIF method for the analysis of synthetic cathinones and amphetamines [Poster presentation]. 36th International Synopsium on Microscale Separations and Bioanalysis.

Fillet, M. (September 2020). Contribution of capillary electrophoresis in the context of drug development and quality control [Paper presentation]. 36th International Symposium on Microscale Separations and Bioanalysis.

Gou, M.-J., Nys, G., COBRAIVILLE, G., Demelenne, A., Servais, A.-C., Caers, J., & Fillet, M. (September 2020). Capillary electrophoresis tandem mass spectrometry for proteomics in the context of multiple myeloma: investigation of two hyphenating approaches [Paper presentation]. 36th International Symposium on Microscale Separations and Bioanalysis.

Nix, C., COBRAIVILLE, G., Nys, G., & Fillet, M. (September 2020). Micro pillar array columns in the context of proteomics studies [Poster presentation]. 36th International Symposium on Microscale Separations and Bioanalysis.

Yazdani, R., Shams-Bakhsh, M., Hassani-Mehraban, A., Arab, S. S., Thelen, N., Thiry, M., Crommen, J., Fillet, M., Jacobs, N., Brans, A., & Servais, A.-C. (September 2020). Characterization of virus-like particles of grapevine fanleaf virus presenting L2 epitope of human papillomavirus minor capsid protein [Poster presentation]. 36th International Symposium on Microscale Separations and Bioanalysis (e-MSB 2020).

Coic, L., Sacre, P.-Y., Dispas, A., Dumont, E., Horne, J., De Bleye, C., Fillet, M., Hubert, P., & Ziemons, E. (01 July 2020). Evaluation of the analytical performances of two Raman handheld spectrophotometers for pharmaceutical solid dosage form quantitation. Talanta, 214, 120888. doi:10.1016/j.talanta.2020.120888

Hemmati, M., Nix, C., Crommen, J., Servais, A.-C., & Fillet, M. (June 2020). Benefits of microsampling and microextraction for metabolomics studies. TrAC: Trends in Analytical Chemistry, 127, 115899. doi:10.1016/j.trac.2020.115899

Ledoux, A., Coelho Cristino Mamede, L. C., Palazzo, C., Furst, T., Jansen, O., De Tullio, P., Kagisha, V., Pendeville-Samain, H., Fillet, M., Piel, G., & Frederich, M. (18 May 2020). Heparin-Coated Liposomes Improve Antiplasmodial Activity and Reduce the Toxicity of Poupartone B. Planta Medica International Open, 7 (e), 73–80. doi:10.1055/a-1158-0569

Nix, C., Nys, G., COBRAIVILLE, G., & Fillet, M. (April 2020). Development and optimization of a micro pillar array column method in the context of proteomics studies [Poster presentation]. The 36th International Symposium on Microscale Separations and Bioanalysis.

Nix, C., Gou, M.-J., Nys, G., COBRAIVILLE, G., & Fillet, M. (February 2020). Microfluidic separation systems coupled to ion-mobility-Q-TOF for comprehensive proteomic analysis in the context of new therapeutic approaches [Paper presentation]. 6th International Ion Mobility Spectrometry (IMS) meeting, Duisburg-Essen, Germany.

Aune, E., Diepeveen, L., Laarallers, C., Klaver, S., Armitage, A., Bansal, S., Chen, M., Fillet, M., Han, H., Herkert, M., Itkonen, O., van der Kerkhof, D., Krygier, A., Lefebvre, T., Neyer, P., Rieke, M., Tomosugi, N., Weykamp, C., & Swinkels, D. (2020). Optimizing hepcidin measurement with a proficiency test framework and standardization improvement. Clinical Chemistry and Laboratory Medicine. doi:10.1515/cclm-2020-0928

Coic, L., Sacre, P.-Y., Dispas, A., Dumont, E., De Bleye, C., Fillet, M., Hubert, P., & Ziemons, E. (January 2020). How to analyse big data in hyperspectral imaging? Application for the elucidation of medicine composition [Poster presentation]. Chimiométrie 2020, Liège, Belgium.

Davoine, C., Simon, F., Bouckaert, C., Lanners, S., Fillet, M., & Pochet, L. (January 2020). Using fragment-based lead discovery to generate new scaffolds for the development of FXIIa inhibitors [Poster presentation]. 2nd Alpine Winter Conference on Medicinal and Synthetic Chemistry, St. Anton, Austria.

Demelenne, A., Gou, M.-J., Nys, G., Parulski, C., Crommen, J., Servais, A.-C., & Fillet, M. (2020). Evaluation of Hydrophilic Interaction Liquid Chromatography, Capillary Zone Electrophoresis and Drift Tube Ion-Mobility Quadrupole Time Of Flight mass spectrometry for the characterization of phosphodiester and phosphorothioate oligonucleotides. Journal of Chromatography. A. doi:10.1016/j.chroma.2019.460716

Dispas, A., Emonts, P., Avohou, T. H., Ziemons, E., Hubert, P., & Fillet, M. (January 2020). Design of experiments approach to optimize FITC labeling process [Poster presentation]. Chimiométrie 2020, Liège, Belgium.

Gou, M.-J., Nys, G., COBRAIVILLE, G., Demelenne, A., Servais, A.-C., & Fillet, M. (2020). Hyphenation of capillary zone electrophoresis with mass spectrometry for proteomic analysis: Optimization and comparison of two coupling interfaces. Journal of Chromatography. A. doi:10.1016/j.chroma.2020.460873

Nix, C., Nys, G., COBRAIVILLE, G., & Fillet, M. (January 2020). Multidimensional performance assessment of micro pillar array column chromatography combined to ion mobility-mass spectrometry for proteomics research [Paper presentation]. 16th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology, Ghent, Belgium.

Nys, G., Nix, C., COBRAIVILLE, G., Servais, A.-C., & Fillet, M. (2020). Enhancing protein discoverability by data independent acquisition assisted by ion mobility mass spectrometry. Talanta. doi:10.1016/j.talanta.2020.120812

Oury, C., MARECHAL, P., Donis, N., Hulin, A., Hego, A., TRIDETTI, J., Nguyen, M.-L., DULGHERU, R. E., Fillet, M., Nchimi Longang, A., & Lancellotti, P. (2020). Dexfenfluramine and Pergolide Cause Heart Valve Disease via Valve Metabolic Reprogramming and Ongoing Matrix Remodeling. International Journal of Molecular Sciences, 21 (11). doi:10.3390/ijms21114003

Pawluski, J. L., Paravatou, R., Even, A., COBRAIVILLE, G., Fillet, M., Kobras, N., Dalla, C., & Charlier, T. D. (2020). Effect of sertraline on central serotonin and hippocampal plasticity in pregnant and non- pregnant rats. Neuropharmacology, 166. doi:10.1016/j.neuropharm.2020.107950

Sambon, M., Gorlova, A., Demelenne, A., Alhama-Riba, J., Coumans, B., Lakaye, B., Wins, P., Fillet, M., Anthony, D. C., Strekalova, T., & Bettendorff, L. (2020). Dibenzoylthiamine has powerful antioxidant and anti-inflammatory properties in cultured cells and in mouse models of stress and neurodegeneration. Biomedicines, 8, 361. doi:10.3390/biomedicines8090361

Coic, L., Sacre, P.-Y., Dispas, A., Dumont, E., De Bleye, C., Fillet, M., Hubert, P., & Ziemons, E. (11 December 2019). Which tools can help to thwart “out of memory” issues during analysis of big data? [Poster presentation]. CIRM Day 2nd edition.

Davoine, C., Farcas, E., Bouckaert, C., Pochet, L., & Fillet, M. (11 December 2019). Flow-through partial-filling affinity capillary electrophoresis for the detection of weak ligand-target interactions: application to coagulation factor XIIa [Poster presentation]. CIRM-day 2019, Liège, Belgium.

Demelenne, A., Gou, M.-J., Nys, G., Parulski, C., Servais, A.-C., & Fillet, M. (11 December 2019). Ion mobility high resolution mass spectrometry coupled to HILIC and CZE for the characterization of phosphodiester and phosphorothioate oligonucleotides [Paper presentation]. 2nd Cirm Day, Liège, Belgium.

Emonts, P., Dispas, A., Servais, A.-C., & Fillet, M. (11 December 2019). Development of a sensitive CE-LIF method for the analysis of synthetic cathinones [Poster presentation]. Paul Emonts, Liege, Belgium.

Gils, M., Ledoux, A., Davoine, C., Desdemoustier, P., Clain, M.-E., Castillo Cabello, G., Frederich, M., & Fillet, M. (11 December 2019). Affinity capillary electrophoresis as a tool for the discovery of new antimalarial natural compounds [Poster presentation]. 2nd CIRM Scientific Day.

Gou, M.-J., Nys, G., COBRAIVILLE, G., Demelenne, A., Servais, A.-C., & Fillet, M. (11 December 2019). Proteomic analysis using capillary electrophoresis hyphenated with high resolution mass spectrometry: comparison of two coupling interfaces [Poster presentation]. 2nd Cirm Day, Liège, Belgium.

Ilangala Booka, A., COBRAIVILLE, G., EVRARD, A., Sonveaux, Lechanteur, A., Piel, G., & Fillet, M. (11 December 2019). LC-UV as tool for nanovectorized anticancer peptide quality control: evaluation of encapsulation efficiency [Poster presentation]. 2nd Edition of CIRM day, Liege, Belgium.

Davoine, C., Farcas, E., Simon, F., Bouckaert, C., Lanners, S., Pochet, L., & Fillet, M. (22 November 2019). Affinity capillary electrophoresis as a powerful tool for fragment-based screening: application to the inhibition of S1A serine proteases implicated in the coagulation cascade [Poster presentation]. Annual One-Day Meeting on Medicinal Chemistry of KVCV & SRC - MedChem2019, Brussels, Belgium.

Nys, G., COBRAIVILLE, G., Servais, A.-C., Malaise, M., DE SENY, D., & Fillet, M. (2019). Targeted proteomics reveals serum amyloid A variants and alarmins S100A8-S100A9 as key plasma biomarkers of rheumatoid arthritis. Talanta. doi:10.1016/j.talanta.2019.06.044

Nys, G., COBRAIVILLE, G., Servais, A.-C., & Fillet, M. (October 2019). Chromatographic and electrophoretic techniques coupled to ion-mobility mass spectrometry for the deciphering of molecular networks [Paper presentation]. 3rd International Symposium on Advances in Pharmaceutical Analysis (APA 2019), Xian, China.

Nyssen, L., Fillet, M., CAVALIER, E., & Servais, A.-C. (26 September 2019). Separation of Intact Parathyroid Hormone and Variants Using a Highly Sensitive Sheathless CE-ESI-MS/MS Method [Poster presentation]. MSACL 2019 EU.

Demelenne, A., Gou, M.-J., Nys, G., Parulski, C., Servais, A.-C., & Fillet, M. (17 September 2019). Quality control of therapeutic phosphorothioate oligonucleotides by hydrophilic interaction liquid chromatography coupled with ION-MOBILITY QTOF [Paper presentation]. 30 th INTERNATIONAL SYMPOSIUM ON PHARMACEUTICAL & BIOMEDICAL ANALYSIS, Tel Aviv, Israel.

Gou, M.-J., Nys, G., Demelenne, A., COBRAIVILLE, G., Servais, A.-C., & Fillet, M. (17 September 2019). Comparison of two capillary electrophoresis-mass spectrometry interfaces for proteomic analysis [Poster presentation]. 30th International Symposium on Pharmaceutical and Biomedical Analysis, Tel Aviv, Israel.

Gou, M.-J., Nys, G., Demelenne, A., COBRAIVILLE, G., Servais, A.-C., & Fillet, M. (01 September 2019). Capillary electrophoresis tandem mass spectrometry for proteomic analysis: optimization and comparison of two coupling interfaces [Poster presentation]. 26th International Symposium on Electroseparation and Liquid Phase-Separation Techniques, Toulouse, France.

Nys, G., COBRAIVILLE, G., Servais, A.-C., & Fillet, M. (September 2019). Evaluation and comparison of different separation techniques coupled to ion-mobility mass spectrometry for the deciphering of molecular networks [Paper presentation]. 26th International Symposium on Electroseparation and liquid-phase separation techniques (ITP 2019), Toulouse, France.

Ion, V., Le Goff, C., Cavalier, E., Delanaye, P., Servais, A.-C., Muntean, D.-L., & Fillet, M. (August 2019). Determination of iohexol by capillary blood microsampling and UHPLC-MS/MS. Journal of Pharmaceutical Analysis, 9 (4), 259-265. doi:10.1016/j.jpha.2019.06.003

Coic, L.* , Sacre, P.-Y.* , Dispas, A., sakira, A. K., Fillet, M., Marini Djang'Eing'A, R., Hubert, P., & Ziemons, E. (01 June 2019). Comparison of hyperspectral imaging techniques for the elucidation of falsified medicines composition. Talanta, 198, 457-463. doi:10.1016/j.talanta.2019.02.032

Coic, L., Sacre, P.-Y., Dispas, A., Fillet, M., Hubert, P., & Ziemons, E. (20 May 2019). HANDHELD RAMAN SPECTROSCOPY: AN ESSENTIAL TOOL TO TACKLE THE SUBSTANDARD MEDICINES ISSUE? [Paper presentation]. BSPS 2019 Forum of Pharmaceutical Sciences, Bruxelles, Belgium.

Demelenne, A., Gou, M.-J., Parulski, C., Servais, A.-C., & Fillet, M. (20 May 2019). Optimisation of the separation of therapeutic phosphorothioate oligonucleotides by hydrophilic interaction liquid chromatography and capillary zone electrophoresis [Paper presentation]. 20th Forum of Pharmaceutical Sciences.

Gou, M.-J., Nys, G., COBRAIVILLE, G., Servais, A.-C., & Fillet, M. (20 May 2019). CE-MS/MS for bottom-up proteomics: comparaison of two coupling interfaces with ion mobility qTOF [Paper presentation]. 20th Forum of Pharmaceutical Sciences, Brussels, Belgium.

DE SENY, D., DEROYER, C., Charlier, E., CIREGIA, F., COBRAIVILLE, G., MEUWIS, M.-A., LOUIS, E., Fillet, M., & MALAISE, M. (May 2019). Increased serological levels of vitronectin(amino acid 381-397) and C3f peptides in osteoarthritis, lupus and scleroderma. Interaction with TGF-β [Poster presentation]. OARSI, Toronto, Canada.

Delage, C., Nys, G., Fillet, M., & Cornil, C. (May 2019). Microglia and prostanoids, potential players in sexual differentiation of the brain and behavior of the Japanese quail [Paper presentation]. Sex differences, dimorphisms, divergences: impact on brain and behavior in health and disease.

Radermecker, R., Demelenne, A., Desaive, T., & Fillet, M. (2019). Analyse des concentrations de quatre type d'insulines différentes ( humaine 100 IU/ml, aspart 100 IU/ml, lispro 200 IU/ml et glargine 300 IU/ml) provenant de trois sources différentes (pharmacie hospitalière , officine de ville , et échantillons procurés au diabétologue par les représentants de l’industrie ). . Diabetes and Metabolism.

Davoine, C., Farcas, E., Thabault, L., Simon, F., Bouckaert, C., Frédérick, R., Lanners, S., Pochet, L., & Fillet, M. (24 March 2019). Capillary electrophoresis and microscale thermophoresis in fragment-based drug discovery : development of screening bioassays towards FXIIa [Poster presentation]. 7th RSC-BMCS Fragment-based Drug Discovery meeting (Fragment 2019), Cambridge, United Kingdom.

Emonts, P., Penoy, N., Rocks, N., Piel, G., Fillet, M., Hubert, P., Ziemons, E., & Evrard, B. (19 January 2019). Update of the progresses and development prospects of the FEDER project Phare [Paper presentation]. CIRM seminars, Liege, Belgium.

Coic, L., Sacre, P.-Y., Avohou, T. H., Ciza, P., Marini Djang'Eing'A, R., Fillet, M., Hubert, P., & Ziemons, E. (01 January 2019). Authentication of falsified medicine tablets by handheld Raman spectroscopy class modeling [Paper presentation]. Chimiométrie 2019, Montpellier, France.

Demelenne, A., NAPP, A., Bouillenne, F., Crommen, J., Servais, A.-C., & Fillet, M. (2019). Insulin aggregation assessment by capillary gel electrophoresis without sodium dodecyl sulfate: Comparison with size-exclusion chromatography. Talanta, 199, 457-463. doi:10.1016/j.talanta.2019.02.074

Huang, Y., Jansen, O., Frederich, M., Mouithys-Mickalad, A., Nys, G., Servais, A.-C., Crommen, J., Jiang, Z., & Fillet, M. (2019). Capillary electrophoresis, high-performance liquid chromatography, and thin-layer chromatography analyses of phenolic compounds from rapeseed plants and evaluation of their antioxidant activity. Journal of Separation Science, 1-10. doi:10.1002/jssc.201800712

Huang, Y., Wang, T., Fillet, M., Crommen, J., & Jiang, Z. (2019). Simultaneous determination of amino acids in different teas using supercritical fluid chromatography coupled with single quadrupole mass spectrometry. Journal of Pharmaceutical Analysis, 9, 254-258. doi:10.1016/j.jpha.2019.05.001

Ion, V., Nys, G., COBRAIVILLE, G., Cavalier, E., Crommen, J., Servais, A.-C., Muntean, D.-L., & Fillet, M. (2019). Ultra-high-performance liquid chromatography-mass spectrometry method for neutrophil gelatinase-associated lipocalin as a predictive biomarker in acute kidney injury. Talanta, 195, 668-675. doi:10.1016/j.talanta.2018.11.050

Kok, M., Nix, C., Nys, G., & Fillet, M. (2019). Targeted metabolomics of whole blood using volumetric absorptive microsampling. Talanta, 197, 49-58. doi:10.1016/j.talanta.2019.01.014

Moldovan, R.-C., Bodoki, E., Servais, A.-C., Crommen, J., Oprean, R., & Fillet, M. (2019). Selectivity evaluation of phenyl based stationary phases for the analysis of amino acid diastereomers by liquid chromatography coupled with mass spectrometry. Journal of Chromatography. A. doi:10.1016/j.chroma.2018.12.068

Nys, G., COBRAIVILLE, G., & Fillet, M. (2019). Multidimensional performance assessment of micro pillar array column chromatography combined to ion mobility-mass spectrometry for proteome research. Analytica Chimica Acta, 1086, 1-13. doi:10.1016/j.aca.2019.08.068

Nyssen, L., Fillet, M., Cavalier, E., & Servais, A.-C. (2019). Highly sensitive and selective separation of intact parathyroid hormone and variants by sheathless CE-ESI-MS/MS. Electrophoresis. doi:10.1002/elps.201800507

Palazzo, C., Laloy, J., Delvigne, A. S., Nys, G., Fillet, M., Dogne, J. M., Pequeux, C., Foidart, J.-M., Evrard, B., & Piel, G. (2019). Development of injectable liposomes and drug-in-cyclodextrin-in-liposome formulations encapsulating estetrol to prevent cerebral ischemia of premature babies. European Journal of Pharmaceutical Sciences, 9 (127), 52-59. doi:10.1016/j.ejps.2018.10.006

Sambon, M., NAPP, A., Demelenne, A., Vignisse, J., Wins, P., Fillet, M., & Bettendorff, L. (2019). Thiamine and benfotiamine protect neuroblastoma cells against paraquat and ß- amyloid toxicity by a coenzyme-independent mechanism. Heliyon, 5, 01710. doi:10.1016/j.heliyon.2019.e01710

Servais, A.-C., & Fillet, M. (2019). Enantioseparations in nonaqueous capillary electrophoresis using charged cyclodextrins. In Methods in Molecular biology: Chiral Separations (pp. 373-381). Humana Press Inc. doi:10.1007/978-1-4939-9438-0_21

Servais, A.-C., & Fillet, M. (2019). Application of dual-cyclodextrin systems in capillary electrophoresis enantioseparations. In Methods in Molecular biology: Chiral Separations (pp. 357-364). Humana Press Inc. doi:10.1007/978-1-4939-9438-0_19

Yazdani, R., Shams-Bakhsh, M., Hassani-Mehraban, A., Arab, S. S., Thelen, N., Thiry, M., Crommen, J., Fillet, M., Jacobs, N., Brans, A., & Servais, A.-C. (2019). Production and characterization of virus-like particles of grapevine fanleaf virus presenting L2 epitope of human papillomavirus minor capsid protein. BMC Biotechnology, 19 (1), 81. doi:10.1186/s12896-019-0566-y

Yazdani, R., Shams-Bakhsh, M., Hassani-Mehraban, A., Shahriar Arab, S., Thelen, N., Thiry, M., Crommen, J., Fillet, M., Jacobs, N., Brans, A., & Servais, A.-C. (2019). Characterization of plant virus-based virus-like particles displaying human papillomavirus L2 epitope [Paper presentation]. 3rd International Symposium on Advances in Pharmaceutical Analysis (APA 2019), Xian, China.

Coelho Cristino Mamede, L. C., Ledoux, A., Desdemoustier, P., Jansen, O., Piel, G., Fillet, M., De Tullio, P., & Frederich, M. (19 December 2018). Quantitative analysis of a natural compound and heparin by HPLC-DAD and 1H NMR for the characterization of a liposomal formulation [Poster presentation]. The first CIRM scientific Day, Liège, Belgium.

Coic, L., Sacre, P.-Y., Dispas, A., Fillet, M., Hubert, P., & Ziemons, E. (19 December 2018). Development of graphical user interface (GUI) for database building and for falsification applications [Paper presentation]. CIRM Day, Belgium.

Davoine, C., Farcas, E., Bouckaert, C., Pochet, L., & Fillet, M. (19 December 2018). Development of fragments screening bioassays towards thrombin and FXIIa using capillary electrophoresis [Poster presentation]. CIRM-day, Liège, Belgium.

Demelenne, A., Napp, A., Radermecker, R., Servais, A.-C., & Fillet, M. (19 December 2018). Quality control and aggregation follow-up of insulin formulations [Paper presentation]. First CIRM scientific day, Liège, Belgium.

Emonts, P., Dispas, A., Ninane, C. (Other coll.), Hubert, P. (Other coll.), Servais, A.-C. (Other coll.), Ziemons, E. (Other coll.), & Fillet, M. (Other coll.). (19 December 2018). Development and optimization of a derivatization protocol for phenethylamine compounds using FITC-CE-LIF method [Poster presentation]. 1st CIRM Scientific Day, Liège, Belgium.

Gou, M.-J., Demelenne, A., Parulski, C., Servais, A.-C., & Fillet, M. (19 December 2018). Quality control of therapeutic oligonucleotides using HILIC-UV and CZE-UV [Poster presentation]. CIRM Day, Liège, Belgium.

Ion, V., Nys, G., COBRAIVILLE, G., CAVALIER, E., Servais, A.-C., Muntean, D.-L., & Fillet, M. (19 December 2018). Targeted LC-MS/MS proteomics approach for the analysis of Neutrophyl Gelatinase Associated Lipocalin in AKI patients [Poster presentation]. 1st CIRM Day, Liège, Belgium.

Kok, M., Nix, C., Nys, G., De Tullio, P., Lecomte, J., LAMBERT, V., & Fillet, M. (19 December 2018). Fluxomics of AMD using mass spectrometry from 10 µL of mice whole blood; investigation of DCA treatment [Poster presentation]. First CIRM Day.

Nys, G., COBRAIVILLE, G., Servais, A.-C., & Fillet, M. (19 December 2018). Data independent acquisition for proteomics studies using ion mobility mass spectrometry [Paper presentation]. CIRM Day, Liège, Belgium.

Nyssen, L., Fillet, M., CAVALIER, E., & Servais, A.-C. (19 December 2018). High sensitive and selective separation of intact parathyroid hormone and related forms by sheathless CE-ESI-MS/MS [Poster presentation]. 1st CIRM Day, Liège, Belgium.

Yazdani, R., Shams-Bakhsh, M., Thelen, N., Thiry, M., Fillet, M., Jacobs, N., Brans, A., & Servais, A.-C. (19 December 2018). Strategies for the study of plant virus-based virus-like particles (VLP) displaying human papillomavirus (HPV) L2 epitope [Poster presentation]. 1st CIRM Day, Liège, Belgium.

DE SENY, D., COBRAIVILLE, G., DEROYER, C., MEUWIS, M.-A., LOUIS, E., Fillet, M., & MALAISE, M. (10 December 2018). Elévation des taux sériques des peptides C3f et vitronectine (acide aminés 381-397) dans l’arthrose, le lupus et la sclérodermie. Interaction avec le TGF-β [Poster presentation]. 31ème Congrès Français de Rhumatologie, Paris, France.

Davoine, C., Farcas, E., Bouckaert, C., Pochet, L., & Fillet, M. (23 November 2018). Development of capillary electrophoresis bioassays for the screening of fragments : application to thrombin and FXIIa [Poster presentation]. Annual One-Day Symposium on Medicinal Chemistry of SRC & KVCV (Medchem 2018), Namur, Belgium.

Legrand, N., Tian, J., Douny, C., Scippo, M.-L., Cambier, C., Fillet, M., Chiap, P., Dubrowski, T., Vandeweerd, J., & Gustin, P. (26 October 2018). Triamcinolone acetonide after intra-articular injection in knee in sheep [Poster presentation]. Proceedings of the 5th FARAH-Day, Liège, Belgium.

Bettonville, V., Nicol, J., Furst, T., Thelen, N., Piel, G., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (October 2018). Study of virus-like particles of human papillomavirus in CE [Paper presentation]. In the framework of High-end Foreign Experts program, Guangzhou, China.

Nys, G., COBRAIVILLE, G., Farcas, E., Demelenne, A., Kok, M., Servais, A.-C., & Fillet, M. (October 2018). Microfluidic analytical approaches to drive drug development [Paper presentation]. In the framework of High-end Foreign Experts program, Guangzhou, China.

Nyssen, L., Fillet, M., CAVALIER, E., & Servais, A.-C. (October 2018). CESI-MS Workflow for Protein Quantification [Poster presentation]. CESI-MS symposium 2018, Leiden, Netherlands.

Yazdani, R., Shams-Bakhsh, M., Hassani-Mehraban, A., Thiry, M., Fillet, M., Brans, A., & Servais, A.-C. (12 September 2018). Combination of analytical approaches for the characterization of plant virus-based VLP displaying HPV L2 epitope [Paper presentation]. 11th International Symposium on Drug Analysis and 29th International Symposium on Pharmaceutical and Biomedical Analysis (DA-PBA 2018), Leuven, Belgium.

Demelenne, A., Napp, A., Servais, A.-C., & Fillet, M. (10 September 2018). Insulin aggregation assessment by size-exclusion chromatography and capillary gel electrophoresis [Poster presentation]. the 11th International Symposium on Drug Analysis and the 29th International Symposium on Pharmaceutical and Biomedical Analysis.

Farcas, E., Servais, A.-C., Hanson, J., Pochet, L., & Fillet, M. (10 September 2018). Partial filling capillary electrophoretic mobility shift competition assay: a versatile and reliable tool for the assessment of weak biomolecular interactions [Paper presentation]. The 11th International Symposium on Drug Analysis and the 29th International Symposium on Pharmaceutical and Biomedical Analysis, Leuven, Belgium.

Kaux, J.-F., Libertiaux, V., Leprince, P., Fillet, M., Denoël, V., LECUT, C., Gothot, A., Le Goff, C., Croisier, J.-L., & Drion, P. (2018). Eccentric training for tendon healing after acute lesion: a rat model. In Towards healthy tendon ageing (pp. 45).

Nys, G., COBRAIVILLE, G., Kok, M., Servais, A.-C., & Fillet, M. (September 2018). Microfluidics coupled to mass spectrometry to decipher molecular networks and monitor active molecules in body fluids [Paper presentation]. 11th International Symposium on Drug Analysis and 29th International Symposium on Pharmaceutical and Biomedical Analysis (DA-PBA 2018), Leuven, Belgium.

Nys, G., COBRAIVILLE, G., Servais, A.-C., & Fillet, M. (31 July 2018). (Nano)-LC coupled to Ion Mobility Q-TOF for an improved sensitivity and proteome coverage [Poster presentation]. HPLC 2018, United States - District of Columbia.

Bettonville, V., Nicol, J., Furst, T., Thelen, N., Piel, G., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (13 July 2018). Strategies for the identification and quantitation of intact virus-like particles of human papillomavirus in CE [Paper presentation]. 2nd International Symposium on Advances in Pharmaceutical Analysis (APA 2018), Lille, France.

Demelenne, A., NAPP, A., Servais, A.-C., & Fillet, M. (12 July 2018). Follow-up of Insulin Aggregation productions in the context of formulation quality control [Poster presentation]. Second international symposium on advanced in Pharmaceutical analysis, Lilles, France.

Farcas, E., Servais, A.-C., Crommen, J., Pochet, L., & Fillet, M. (July 2018). Electrodriven methodologies for the screening of new antithrombotic drugs [Paper presentation]. 2nd International Symposium on Advances in Pharmaceutical Analysis (APA 2018), Lille, France.

Nys, G., COBRAIVILLE, G., Demelenne, A., Servais, A.-C., & Fillet, M. (12 June 2018). ion mobility Q-TOF, an attractive tool for biomarker discovery and biopharmaceutical analysis [Paper presentation]. Agilent Day BELUX, Gent, Belgium.

Farcas, E., Pochet, L., & Fillet, M. (June 2018). Transverse diffusion of laminar flow profiles as a generic capillary electrophoresis method for in-line nanoreactor mixing: application to the investigation of antithrombotic activity. Talanta, 188, 516-521. doi:10.1016/j.talanta.2018.06.014

Kok, M., Nys, G., & Fillet, M. (23 May 2018). Volumetric absorptive microsampling for targeted metabolomics of whole blood [Paper presentation]. 11ème Journées Scientifiques du Réseau Francophone de Métabolomique et Fluxomique (RFMF), Liège, Belgium.

Bettonville, V., Nicol, J., Furst, T., Thelen, N., Piel, G., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (15 March 2018). Analyse de pseudo-particules virales intactes de papillomavirus humain par électrophorèse capillaire : stratégies pour l’identification et la quantification [Paper presentation]. Analytics & Biologics : de la cellule à la petite molécule ?.

STREEL, S., Vercheval, C., Servais, A.-C., Fillet, M., & Van Hees, T. (24 February 2018). Stability of 90 mg/ml cefuroxime sodium solution for administration by continuous infusion [Poster presentation]. Assemble Générale de l'Association Francophone des Pharmaciens Hospitaliers de Belgique, Mons, Belgium.

Nys, G., COBRAIVILLE, G., & Fillet, M. (18 January 2018). Strategies to improve sensitivity and proteome coverage using ion mobility Q-TOF [Paper presentation]. European Ion mobility meeting, Utrecht, Netherlands.

Diepeveen, L. E., Laarakkers, C. M. M., Martos, G., Pawlak, M. E., Uǧuz, F. F., Verberne, K. E. S. A., Van Swelm, R. P. L., Klaver, S., De Haan, A. F. J., Pitts, K. R., Bansal, S. S., Abbas, I. M., Fillet, M., Lefebvre, T., Geurts-Moespot, A. J., Girelli, D., Castagna, A., Herkert, M., Itkonen, O., ... Swinkels, D. W. (2018). Provisional standardization of hepcidin assays: Creating a traceability chain with a primary reference material, candidate reference method and a commutable secondary reference material. Clinical Chemistry and Laboratory Medicine. doi:10.1515/cclm-2018-0783

Farcas, E., Hanson, J., Pochet, L., & Fillet, M. (2018). Capillary electrophoretic mobility shift displacement assay for the assessment of weak drug-protein interactions. Analytica Chimica Acta. doi:10.1016/j.aca.2018.06.024

Gemmel, M., Harmeyer, D., Bögi, E., Fillet, M., Hill, L. A., Hammond, G. L., Charlier, T. D., & Pawluski, J. L. (2018). Perinatal fluoxetine increases hippocampal neurogenesis and reverses the lasting effects of pre-gestational stress on serum corticosterone, but not on maternal behavior, in the rat dam. Behavioural Brain Research, 339, 222-231. doi:10.1016/j.bbr.2017.11.038

Huang, Y., Tang, G., Zhang, T., Fillet, M., Crommen, J., & Jiang, Z. (2018). Supercritical Fluid Chromatography in Traditional Chinese Medicine Analysis. Journal of Pharmaceutical and Biomedical Analysis, 147, 65-80. doi:10.1016/j.jpba.2017.08.021

Kok, M., & Fillet, M. (2018). Volumetric absorptive microsampling: Current advances and applications. Journal of Pharmaceutical and Biomedical Analysis, 147 (5), 288-296. doi:10.1016/j.jpba.2017.07.029

Moldovan, R.-C., Bodoki, E., Servais, A.-C., Chankvetadze, B., Crommen, J., Oprean, R., & Fillet, M. (2018). Capillary electrophoresis-mass spectrometry of derivatized amino acids for targeted neurometabolomics – pH mediated reversal of diastereomer migration order. Journal of Chromatography. A, 1564, 199-206. doi:10.1016/j.chroma.2018.06.030

Napp, A., Houbart, V., Demelenne, A., Merville, M.-P., Crommen, J., Dumoulin, M., Garraux, G., Servais, A.-C., & Fillet, M. (2018). Separation and determination of alpha-synuclein monomeric and oligomeric species using two electrophoretic approaches. Electrophoresis, 39 (23), 3022-3031. doi:10.1002/elps.201800224

Nys, G., & Fillet, M. (2018). Microfluidics contribution to pharmaceutical sciences: From drug discovery to post marketing product management. Journal of Pharmaceutical and Biomedical Analysis, 159, 348-362. doi:10.1016/j.jpba.2018.07.011

Tang, G., Huang, Y., Zhang, T., Wang, Q., Crommen, J., Fillet, M., & Jiang, Z. (2018). Determination of phenolic acids in extra virgin olive oil using supercritical fluid chromatography coupled with single quadrupole mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 157, 217-225. doi:10.1016/j.jpba.2018.05.025

Vercheval, C., STREEL, S., Servais, A.-C., Fillet, M., & Van Hees, T. (2018). Stability of 90 mg/mL cefuroxime sodium solution for administration by continuous infusion. Journal of Chemotherapy, 30 (6-8), 371-374. doi:10.1080/1120009X.2018.1535950

BEKAERT, S., Fillet, M., Detry, B., Pichavant, M., Marée, R., Noël, A., Rocks, N., & Cataldo, D. (21 December 2017). Inflammation-Generated Extracellular Matrix Fragments Drive Lung Metastasis. Cancer Growth and Metastasis, 10, 1-11. doi:10.1177/1179064417745539

Nys, G., Kok, M., Servais, A.-C., & Fillet, M. (December 2017). Beyond dried blood spot: Current microsampling techniques in the context of biomedical applications. TrAC: Trends in Analytical Chemistry, 97, 326-332. doi:10.1016/j.trac.2017.10.002

Amorim, C., Andris, F., Arckens, L., Arnould, T., Aron, S., Bakker, J., Balligand, M., Balthazart, J., Baron, F., Beck, B., Beguin, Y., Behets, C., Bellefroid, E., Bertrand, L., Bettendorff, L., Bindels, L., Blankert, B., Blanpain, C., Bondue, A., ... Wittamer, V. (2017). L’expérimentation animale reste indispensable (OPINION). La Libre Belgique.

Nys, G., COBRAIVILLE, G., DE SENY, D., & Fillet, M. (14 November 2017). Targeted analysis of potential biomarkers of rheumatoid arthritis by LC-MS/MS [Paper presentation]. CIRM seminar, Liège, Belgium.

Nys, G., Kok, M., & Fillet, M. (14 November 2017). Metabolomic and proteomic biomarker quantification in the context of personalized medicin [Paper presentation]. Séminaires Scientifiques du CIRM.

Kok, M., & Fillet, M. (08 November 2017). Quantitative profiling of endogenous polar metabolites from low volumes of blood samples [Paper presentation]. 46th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Jeju, South Korea.

Nys, G., COBRAIVILLE, G., Kok, M., Wéra, O., Servais, A.-C., & Fillet, M. (November 2017). Comparison of nanofluidic and ultra-high performance liquid chromatography-tandem mass spectrometry for high sensitive pharmacokinetic studies of estrogens starting from whole blood microsampling. Journal of Chromatography. A, 1524, 160-168. doi:10.1016/j.chroma.2017.10.006

Kok, M., & Fillet, M. (05 October 2017). Quantitative profiling of endogenous polar metabolites from low volumes of blood samples [Poster presentation]. Conférence de Spectrométrie de Masse, Métabolomique et Fluxomique & Electrophorèse et Analyse Protéomique (SMMAP), Marne-la-Vallée, France.

Bettonville, V., Nicol, J., Furst, T., Thelen, N., Piel, G., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (19 September 2017). Identification and quantitation of intact virus-like particles of human papillomavirus (HPV-VLP) using capillary electrophoresis [Paper presentation]. CE Pharm 2017.

Napp, A., Houbart, V., Demelenne, A., Servais, A.-C., & Fillet, M. (18 September 2017). Challenges in the determination of amyloid oligomeric species by two electrophoretic techniques [Poster presentation]. CE-PHARM 2017, Boston, United States.

Farcas, E., Servais, A.-C., Bouckaert, C., Crommen, J., Pochet, L., & Fillet, M. (13 September 2017). Partial filling affinity capillary electrophoresis as a useful tool for fragment-based drug discovery: A proof of concept on thrombin [Paper presentation]. EDT PhD day, Spa, Belgium.

Kok, M., Thiry, J., Evrard, B., Nys, G., & Fillet, M. (12 September 2017). Sampling only 10 μL of whole blood to study the bioavailability of itraconazole formulations in rats [Paper presentation]. International Symposium on Electro- and Liquid Phase- Separation Techniques (ITP), Sopot, Poland.

Fillet, M., Thiry, J., Evrard, B., Nys, G., Servais, A.-C., & Kok, M. (September 2017). Blood microsampling for itraconazole pharmacokinetic study on individual rodent in the context of drug formulation optimization [Paper presentation]. Recent Developments in Pharmaceutical Analysis (RDA 2017), Rimini, Italy.

Fillet, M. (August 2017). Analytical strategies for sensitive quantitation of drugs and biomarkers from low blood sample volumes [Paper presentation]. 8th Annual Congress on Analytical and Bioanalytical techniques, Brussels, Belgium.

Huang, Y., Fillet, M., Crommen, J., & Jiang, Z. (02 July 2017). Simultaneous Determination of Free Amino Acid Content in Different Teas using Supercritical Fluid Chromatography Coupled with Single Quadrupole Mass Spectrometry [Poster presentation]. 28th International Symposium on Pharmaceutical and Biomedical Analysis, Madrid, Spain.

Crommen, J., Moldovan, R.-C., Bodoki, E., Servais, A.-C., Oprean, R., & Fillet, M. (July 2017). Fully automated MEKC-MS method with in-capillary derivatization for the chiral analysis of amino acids [Paper presentation]. 28th International Symposium on Pharmaceutical and Biomedical Analysis, Madrid, Spain.

Fillet, M., Nys, G., Servais, A.-C., & Kok, M. (July 2017). Evaluation of crude biofluid microsampling methods from living animal models for sensitive quantitation of pharmacologically active molecules [Paper presentation]. 28th International Symposium on Pharmaceutical and Biomedical Analysis (PBA 2017), Madrid, Spain.

Demelenne, A., Napp, A., Lamalle, C., Servais, A.-C., & Fillet, M. (21 June 2017). Quality control of insulin formulations: API , protamine and aggregates follow-up [Poster presentation]. The 45th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC), Prague, Czechia.

Chira, R., Bodoki, E., Sandor, V., Fillet, M., Kilar, F., & Blankert, B. (20 June 2017). Recent advances on the oxidative biotransformation of several beta-blockers [Poster presentation]. 45th International Symposium on High Performance Liquid Phase Separations and Related Techniques- HPLC, Prague, Czechia.

Farcas, E., Bouckaert, C., Servais, A.-C., Crommen, J., Pochet, L., & Fillet, M. (20 June 2017). Optimization of an electrophoretic approach for the screening and the development of new antithrombotic drugs [Paper presentation]. The 45th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC), Prague, Czechia.

Farcas, E., Bouckaert, C., Servais, A.-C., Crommen, J., Pochet, L., & Fillet, M. (19 June 2017). Optimiaztion of an electrophoretic approach for the screening and the development of new antithrombotic drugs [Poster presentation]. The 45th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC), Prague, Czechia.

Huang, Y., Jiang, Z., Fillet, M., & Crommen, J. (18 June 2017). DEVELOPMENT AND VALIDATION OF A FAST SFC METHOD FOR THE ANALYSIS OF FLAVONOIDS IN PLANT EXTRACTS [Poster presentation]. HPLC 2017- 45th International Symposium on High Performance Liquid Separations and Related Techniques, Prague, Czechia.

Nys, G., Gallez, A., Kok, M., COBRAIVILLE, G., Servais, A.-C., Piel, G., Pequeux, C.* , & Fillet, M.*. (05 June 2017). Whole blood microsampling for the quantitation of estetrol without derivatization by liquid chromatography-tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 140, 258-265. doi:10.1016/j.jpba.2017.02.060

Moldovan, R.-C., Bodoki, E., Servais, A.-C., Crommen, J., Oprean, R., & Fillet, M. (June 2017). Separation of FLEC diastereomers by CE vs. LC approaches in the context of neurometabolomics [Poster presentation]. 45th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Prague, Czechia.

Delage, C., Nys, G., Fillet, M., & Cornil, C. (2017). Potential role of microglia and prostaglandins in the sexual differentiation of brain and behavior of Japanese quail. Frontiers in Neuroscience. doi:10.3389/conf.fnins.2017.94.00103

Delage, C., Nys, G., Fillet, M., & Cornil, C. (May 2017). Role of microglia and prostaglandins in estrogen-dependent sexual differentiation of brain and behavior [Poster presentation]. Euron PhD workshop & Symposium: Microglia in development and disease, Hasselt, Belgium.

Delage, C., Nys, G., Fillet, M., & Cornil, C. (May 2017). Potential role of microglia and prostaglandins in the sexual differentiation of brain and behavior of Japanese quail [Poster presentation]. 12ième congrès national de la société belge de neuroscience, Ghent, Belgium.

Kaux, J.-F., Libertiaux, V., Leprince, P., Fillet, M., Denoël, V., Wyss, C., LECUT, C., Gothot, A., Le Goff, C., Croisier, J.-L., Crielaard, J.-M., & Drion, P. (May 2017). Eccentric training for tendon healing after lesion: a rat model. American Journal of Sports Medicine, 45 (6), 1440-1446. doi:10.1177/0363546517689872

Nys, G., Servais, A.-C., Pequeux, C., & Fillet, M. (29 March 2017). Lc-chip versus UHPLC-tandem mass spectrometry for the quantitation of estetrol and estradiol without derivatization after whole blood microsampling [Paper presentation]. 12éme congrès francophone sur les sciences séparatives et les couplages, Paris, France.

Bettonville, V., Nicol, J., Furst, T., Thelen, N., Piel, G., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (March 2017). Strategies for the identification and quantitation of virus-like particles of human papillomavirus using capillary electrophoresis [Poster presentation]. Analytical Technologies Europe 2017.

Fillet, M., Nys, G., Servais, A.-C., & Pequeux, C. (March 2017). MICROSAMPLING AND MICROPREPARATION OF BIOLOGICAL FLUIDS FOR SENSITIVE QUANTITATION OF ESTETROL BY LC-(CHIP)-MS/MS [Paper presentation]. Microscale separation and bioanalysis (MSB).

Nys, G., Servais, A.-C., Pequeux, C., & Fillet, M. (March 2017). Microsampling and micropreparation of biological fluids for sensitive quantitation of estetrol by LC-(Chip)-MS/MS [Paper presentation]. 33th International Symposium on Microscale Bioseparations (MSB), Madrid, Spain.

Thiry, J., Kok, M., Collard, L., Frere, A., Krier, F., Fillet, M., & Evrard, B. (01 March 2017). Bioavailability enhancement of itraconazole-based solid dispersions produced by hot melt extrusion in the framework of the Three Rs rule. European Journal of Pharmaceutical Sciences, 99, 1-8. doi:10.1016/j.ejps.2016.12.001

Delage, C., Nys, G., Fillet, M., & Cornil, C. (01 February 2017). Investigating the role of microglia and prostaglandins in sexual differentiation of brain and behavior mediated by estrogens [Paper presentation]. GIGA Day, Liège, Belgium.

Bettonville, V., Nicol, J., Furst, T., Thelen, N., Piel, G., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (2017). Study of virus-like particles of human papillomavirus in capillary electrophoresis [Poster presentation]. 33rd International Symposium on Microscale Separations and Bioanalysis (MSB 2017), Noordwijkerhout, Netherlands.

Bettonville, V., Nicol, J. T. J., Furst, T., Thelen, N., Piel, G., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (2017). Quantitation and biospecific identification of virus-like particles of human papillomavirus by capillary electrophoresis. Talanta, 175, 325-330. doi:10.1016/j.talanta.2017.07.046

COBRAIVILLE, G., Fillet, M., Sharif, M., Ourradi, K., Nys, G., Malaise, M., & DE SENY, D. (2017). Validation of a new method by nano-liquid chromatography on chip tandem mass spectrometry for combined quantitation of C3f and the V65 vitronectin fragment as biomarkers of diagnosis and severity of osteoarthritis. Talanta, 169, 170-180. doi:10.1016/j.talanta.2017.03.078

Delplanques, T., Boulahjar, R., Charton, J., Houze, C., Howsam, M., Servais, A.-C., Fillet, M., & Lipka, E. (2017). Single and dual cyclodextrins systems for the enantiomeric and diastereoisomeric separations of structurally related dihydropyridone analogues. Electrophoresis. doi:10.1002/elps.201600536

Farcas, E., Bouckaert, C., Servais, A.-C., Hanson, J., Pochet, L., & Fillet, M. (2017). Partial filling affinity capillary electrophoresis as a useful tool for fragment-based drug discovery: A proof of concept on thrombin. Analytica Chimica Acta, 984, 211-222. doi:10.1016/j.aca.2017.06.035

Farcas, E., Pochet, L., Crommen, J., Servais, A.-C., & Fillet, M. (2017). Capillary electrophoresis in the context of drug discovery. Journal of Pharmaceutical and Biomedical Analysis. doi:10.1016/j.jpba.2017.02.022

Fettweis, G., Di Valentin, E., L'homme, L., Lassence, C., Dequiedt, F., Fillet, M., Coupienne, I., & Piette, J. (2017). RIP3 antagonizes a TSC2-mediated pro-survival pathway in glioblastoma cell death. Biochimica et Biophysica Acta. doi:10.1016/j.bbamcr.2016.10.014

Huang, Y., Feng, Y., Tang, G., Li, M., Zhang, T., Fillet, M., Crommen, J., & Jiang, Z. (2017). Development and validation of a fast SFC method for the analysis of flavonoids in plant extracts. Journal of Pharmaceutical and Biomedical Analysis, 140, 384-391. doi:10.1016/j.jpba.2017.03.012

Huang, Y., Zhang, T., Zhao, Y., Zhou, H., Tang, G., Fillet, M., Crommen, J., & Jiang, Z. (2017). Simultaneous analysis of nucleobases, nucleosides and ginsenosides in ginseng extracts using supercritical fluid chromatography coupled with single quadrupole mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 144, 213-219. doi:10.1016/j.jpba.2017.03.059

Moldovan, R.-C., Bodoki, E., Servais, A.-C., Crommen, J., Oprean, R., & Fillet, M. (2017). (+) or (-)-1-(9-fluorenyl)ethyl chloroformate as chiral derivatizing agent: A review. Journal of Chromatography. A, 1513, 1-17. doi:10.1016/j.chroma.2017.07.045

Thiry, J., Evrard, B., Nys, G., Fillet, M., & Kok, M. (2017). Sampling only ten microliters of whole blood for the quantification of poorly soluble drugs: Itraconazole as case study. Journal of Chromatography. A, 1479, 161-168. doi:10.1016/j.chroma.2016.12.009

Palazzo, C., Laloy, J., Delvigne, A.-S., Nys, G., Dogne, J.-M., Fillet, M., Foidart, J.-M., Evrard, B., & Piel, G. (December 2016). NEW INJECTABLE LIPOSOME AND DRUG-IN-CYCLODEXTRIN-IN LIPOSOME SYSTEMS ENCAPSULATING ESTETROL FOR THE TREATMENT OF ISCHEMIA DISEASES IN PREMATURE BABIES [Poster presentation]. Journées annuelles SFNano, Paris 2016, Paris, France.

Thiry, J., Kok, M., Collard, L., Frère, A., Krier, F., Fillet, M., & Evrard, B. (15 November 2016). Original study of the bioavailability enhancement of itraconazole-based solid dispersions produced by hot melt extrusion in the framework of the three Rs rule [Poster presentation]. AAPS 2016 Denver.

Bettonville, V., Nicol, J., Thelen, N., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (14 November 2016). Quantitation and biospecific identification of virus-like particles of human papillomavirus using capillary electrophoresis [Paper presentation]. 27th International Symposium on Pharmaceutical and Biomedical Analysis (PBA 2016), Guangzhou, China.

Huang, Y., Fillet, M., Zhang, T., Crommen, J., & Jiang, Z. (13 November 2016). Determination of saccharides in honey using supercritical fluid chromatography coupled with single quadrupole mass spectrometry [Poster presentation]. 27th International Symposium on Pharmaceutical and Biomedical Analysis.

Nys, G., Servais, A.-C., Pequeux, C., & Fillet, M. (17 October 2016). Pharmacokinetic study of estetrol in murin model developing a whole blood microsampling, extraction procedure and an UHPLC-MS/MS method [Paper presentation]. Forum of pharmaceutical sciences, Brussels, Belgium.

Chira, R., Ede, B., Moldovan, R.-C., Fillet, M., & Oprean, R. (01 October 2016). Study of oxidative metabolization of beta-blockers by capillary electrophoresis and mass spectrometry techniques [Paper presentation]. 16th National Congress for Pharmacy, Bucharest, Romania.

Demelenne, A., Napp, A., Servais, A.-C., & Fillet, M. (October 2016). Study of insulin aggregation by SEC and CGE [Paper presentation]. 19th Forum of Pharmaceutical Sciences, Bruxelles, Belgium.

Farcas, E., Servais, A.-C., Lamalle, C., CHIAP, P., Pochet, L., & Fillet, M. (01 October 2016). OPTIMIZATION OF A FULLY AUTOMATED ELECTROPHORETICALLY MEDIATED MICROANALYSIS SYSTEM FOR CYP1A1 ACTIVITY MONITORING [Paper presentation]. The 16th Edition of National Congress of Pharmacy in Romania, Bucharest, Romania.

Bettonville, V., Nicol, J., Thelen, N., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (28 September 2016). Stratégies pour l'identification et la quantification de pseudo-particules virales de papillomavirus humain par électrophorèse capillaire [Paper presentation]. 9èmes journées scientifiques de l'Association Francophone pour l'étude des Infections à Papillomavirus et Polyomavirus.

Palazzo, C., Laloy, J., Delvigne, A.-S., Nys, G., Dogne, J.-M., Karim, R., Fillet, M., Foidart, J.-M., Evrard, B., & Piel, G. (28 September 2016). INNOVATIVE INJECTABLE LIPOSOME AND DRUG-IN-CYCLODEXTRIN-IN LIPOSOME SYSTEMS ENCAPSULATING ESTETROL FOR THE TREATMENT OF ISCHEMIA DISEASES IN PREMATURE BABIES [Paper presentation]. 4th Congress on Innovation in Drug Delivery, Antibes-Juan-Les-Pins, France.

DE SENY, D., COBRAIVILLE, G., Leprince, P., Fillet, M., Collin, C., Mathieu, M., HAUZEUR, J.-P., Gangji, V., & Malaise, M. (2016). Biomarkers of inflammation and innate immunity in atrophic nonunion fracture. Journal of Translational Medicine. doi:10.1186/s12967-016-1019-1

LE GOFF, C., Kaux, J.-F., D'OTREPPE DE BOUVETTE, S., Goffaux, S., Fillet, M., Chapelle, J.-P., & Cavalier, E. (August 2016). Release of cardiac biomarkers during a cycling race. World Journal of Cardiovascular Diseases, 6 (8), 285-294.

Chira, R., Bodoki, E., Moldovan, R.-C., Fillet, M., & Oprean, R. (10 July 2016). Study of the oxidative metabolic patway of beta-blockers by capillary electrophoresis coupled with mass spectrometry [Paper presentation]. 16th CEEPUS Symposium and Summer School on Bioanalysis, Warsaw, Poland.

Furst, T., Bettonville, V., Farcas, E., Frère, A., Lechanteur, A., Evrard, B., Fillet, M., Piel, G., & Servais, A.-C. (2016). Capillary electrophoresis method to determine siRNA complexation with cationic liposomes. Electrophoresis. doi:10.1002/elps.201600249

Fillet, M. (19 May 2016). Discovery and quantification of new biomarkers for preventive and predictive medicine [Paper presentation]. CIRM seminars, Liege, Belgium.

Napp, A., Houbart, V., Servais, A.-C., Merville, M.-P., Garraux, G., & Fillet, M. (19 May 2016). Analytical Challenges for the determination of alpha-synuclein and its oligomeric forms in the context of parkinson disease [Paper presentation]. Séminaire du CIRM.

Houbart, V., COBRAIVILLE, G., Nys, G., Servais, A.-C., & Fillet, M. (May 2016). Volumetric Absorptive Microsampling for Hepcidin Peptide Extraction from Whole Blood. LC GC North America, 34 (5).

Houbart, V., Napp, A., Rudaz, S., Schappler, J., & Fillet, M. (April 2016). Alpha-synuclein as biomarker in Parkinson’s disease: strategies for detection in CGE-LIF [Paper presentation]. 32nd International Symposium on Microscale Separations and Bioanalysis (MSB 2016), Niagara-on-the-lake, Canada.

Houbart, V., Napp, A., Rudaz, S., Schappler, J., & Fillet, M. (April 2016). Alpha-synuclein as biomarker in Parkinson’s disease: strategies for detection in CGE-LIF [Poster presentation]. 32nd International Symposium on Microscale Separations and Bioanalysis (MSB 2016), Niagara-on-the-lake, Canada.

Bettonville, V., Nicol, J., Thelen, N., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (2016). Study of intact virus-like particles of human papillomavirus by capillary electrophoresis. Electrophoresis, 37, 579-586. doi:10.1002/elps.201500431

Denamur, S., Boland, L., Beyaert, M., Verstraeten, S. L., Fillet, M., Tulkens, P. M., Bontemps, F., & Mingeot-Leclercq, M.-P. (2016). Subcellular mechanisms involved in apoptosis induced by aminoglycoside antibiotics: Insights on p53, proteasome and endoplasmic reticulum. Toxicology and Applied Pharmacology, 309, 24-36. doi:10.1016/j.taap.2016.08.020

Farcas, E., Servais, A.-C., Lamalle, C., CHIAP, P., Pochet, L., & Fillet, M. (2016). Fully automated electrophoretically mediated microanalysis for CYP1A1 activity monitoring optimized by multivariate approach. Electrophoresis, 37 (2), 248-255. doi:10.1002/elps.201500214

Frederich, M., Pirotte, B., Fillet, M., & De Tullio, P. (2016). Metabolomics as a Challenging Approach for Medicinal Chemistry and Personalized Medicine. Journal of Medicinal Chemistry, 59 (19), 8649–8666. doi:10.1021/acs.jmedchem.5b01335

Heusschen, R., Muller, J., Fillet, M., Vanderkerken, K., Thijssen, V., Cohen-Solal, M., BEGUIN, Y., & CAERS, J. (2016). Lectin-glycoprotein interactions in the diagnosis and biology of myeloma-related bone disease [Poster presentation]. 2nd Herbert Fleisch Workshop of the International Bone and Mineral Society, Brugge, Belgium.

Houbart, V., COBRAIVILLE, G., Nys, G., Merville, M.-P., & Fillet, M. (2016). Impact of injection solvent composition on protein identification incolumn-switching chip-liquid chromatography/mass spectrometry. Journal of Chromatography. A, 1445, 27-35. doi:10.1016/j.chroma.2016.03.056

Lamalle, C., Servais, A.-C., Demelenne, A., Crommen, J., & Fillet, M. (2016). Analysis of protamine peptides in insulin pharmaceutical formulations by capillary electrophoresis. Journal of Separation Science, 39 (6), 1189-94. doi:10.1002/jssc.201501093

Moldovan, R.-C., Bodoki, E., Kacso, T., Servais, A.-C., Crommen, J., Oprean, R., & Fillet, M. (2016). A micellar electrokinetic chromatography–mass spectrometry approach using in-capillary diastereomeric derivatization for fully automatized chiral analysis of amino acids. Journal of Chromatography. A. doi:10.1016/j.chroma.2016.08.035

Prior, A., Moldovan, R.-C., Crommen, J., Servais, A.-C., Fillet, M., de Jong, G. J., & Somsen, G. W. (2016). Enantioselective capillary electrophoresis-mass spectrometry of amino acids in cerebrospinal fluid using a chiral derivatizing agent and volatile surfactant. Analytica Chimica Acta, 940, 150-8. doi:10.1016/j.aca.2016.08.040

Servais, A.-C., Janicot, B., Takam, A., Crommen, J., & Fillet, M. (2016). Liquid chromatography separation of the chiral prodrug eslicarbazepine acetate and its main metabolites in polar organic mode. Application to their analysis after in vitro metabolism. Journal of Chromatography. A, 1467, 306-311. doi:10.1016/j.chroma.2016.07.022

van der Vorm, L. N., Hendriks, J. C. M., Laarakkers, C. M., Klaver, S., Armitage, A. E., Bamberg, A., Geurts-Moespot, A. J., Girelli, D., Herkert, M., Itkonen, O., Konrad, R. J., Tomosugi, N., Westerman, M., Bansal, S. S., Campostrini, N., Drakesmith, H., Fillet, M., Olbina, G., Pasricha, S.-R., ... Swinkels, D. W. (2016). Toward Worldwide Hepcidin Assay Harmonization: Identification of a Commutable Secondary Reference Material. Clinical Chemistry, 62 (7), 993-1001. doi:10.1373/clinchem.2016.256768

Fillet, M. (14 October 2015). Optimisation of analytical methods [Paper presentation]. In the framework of High-end Foreign Experts program, Guangzhou, China.

Houbart, V., COBRAIVILLE, G., Crommen, J., Servais, A.-C., & Fillet, M. (13 October 2015). Peptide biomarker quantitation from small volume of blood [Paper presentation]. In the framework of High-end Foreign Experts program, Guangzhou, China.

Fillet, M. (12 October 2015). Is quality control of medicines important? [Paper presentation]. In the framework of High-end Foreign Experts program.

Bettonville, V., Nicol, J., Thelen, N., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (08 September 2015). Analysis of intact virus-like particles of human papillomavirus (HPV-VLP) in capillary electrophoresis [Poster presentation]. UniGR workshop: from drug target to drug development.

Farcas, E., Servais, A.-C., Lamalle, C., Chiap, P., Pochet, L., & Fillet, M. (08 September 2015). OPTIMIZATION OF A FULLY AUTOMATED ELECTROPHORETICALLY MEDIATED MICROANALYSIS SYSTEM FOR CYP1A1 ACTIVITY MONITORING [Poster presentation]. UniGR workshop: From drug target to drug development.

HANNON, M., BEGUIN, Y., Ehx, G., SERVAIS, S., SEIDEL, L., Graux, C., Maertens, J., Kerre, T., Daulne, C., de Bock, M., Fillet, M., ORY, A., WILLEMS, E., GOTHOT, A., Humblet-Baron, S., & BARON, F. (15 July 2015). Immune Recovery after Allogeneic Hematopoietic Stem Cell Transplantation following Flu-TBI versus TLI-ATG Conditioning. Clinical Cancer Research, 21 (14), 3131-9. doi:10.1158/1078-0432.CCR-14-3374

Bettonville, V., Nicol, J., Thelen, N., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (July 2015). Characterization of intact virus-like particles of human papillomavirus 16 (HPV16-VLP) in capillary electrophoresis [Paper presentation]. 26th International Symposium on Pharmaceutical and Biomedical Analysis (PBA 2015), Tbilisi, Georgia.

Houbart, V., COBRAIVILLE, G., Crommen, J., Servais, A.-C., & Fillet, M. (July 2015). Analytical strategies for sensitive peptide quantitation from low blood sample volumes [Paper presentation]. 26th International Symposium on Pharmaceutical and Biomedical Analysis (PBA 2015), Tbilisi, Georgia.

Moldovan, R.-C., Kacso, T., Servais, A.-C., Crommen, J., Oprean, R., & Fillet, M. (01 July 2015). D and L amino acid profiling using in-line derivatization and MEKC-ESI-MS [Poster presentation]. 21st International Symposium on Separation Science, Ljubljana, Slovenia.

Bettonville, V., Nicol, J., Thelen, N., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (24 June 2015). Analysis of intact virus-like particles of human papillomavirus (HPV-VLP) in capillary electrophoresis [Paper presentation]. HPLC 2015.

Farcas, E., Servais, A.-C., Lamalle, C., Chiap, P., Pochet, L., & Fillet, M. (23 June 2015). FULLY AUTOMATED ELECTROPHORETICALLY MEDIATED MICROANALYSIS SYSTEM FOR CYP1A1 ACTIVITY MONITORING [Poster presentation]. HPLC 2015, Geneva, Switzerland.

Bettonville, V., Nicol, J., Thelen, N., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (28 May 2015). Capillary electrophoretic analysis of intact virus-like particles of human papillomavirus (HPV-VLP) [Paper presentation]. 18th Forum of Pharmaceutical Sciences.

Farcas, E., Servais, A.-C., Lamalle, C., Chiap, P., Pochet, L., & Fillet, M. (28 May 2015). Fully automated electrophoretically mediated microanalysis system for CYP1A1 activity monitoring [Paper presentation]. THE 18th FORUM OF PHARMACEUTICAL SCIENCES, Blankenberge, Belgium.

Bettonville, V., Nicol, J., Thelen, N., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (23 April 2015). Study of virus-like particules of human papillomavirus (HPV-VLP) by capillary electrophoresis [Paper presentation]. Séminaire du CIRM.

Crommen, J., Lamalle, C., Servais, A.-C., & Fillet, M. (2015). Separation and determination of insulins and analogs by micellar electrokinetic chromatography [Paper presentation]. 26th International Symposium on Pharmaceutical and Biomedical Analysis (PBA), Tbilisi, Georgia.

Deroyer, C., Magne, J., Moonen, M., Le Goff, C., Dupont, L., Hulin, A., Radermecker, M., Colige, A., Cavalier, E., Kolh, P., Pierard, L., LANCELLOTTI, P., Merville, M.-P., & Fillet, M. (2015). New biomarkers for primary mitral regurgitation. Clinical Proteomics, 12, 25. doi:10.1186/s12014-015-9097-2

Fillet, M. (2015). Microfluidic analytical techniques in drug discovery [Paper presentation]. UniGR workshop: From Drug Target To Drug Development, Arlon, Belgium.

Fillet, M., & Frederich, M. (2015). The emergence of metabolomics as a key discipline in the drug discovery process. Drug Discovery Today. Technologies, 13, 19-24. doi:10.1016/j.ddtec.2015.01.006

Houbart, V., COBRAIVILLE, G., Servais, A.-C., & Fillet, M. (2015). Dried spot sampling for hepcidin quantitation in human blood by microfluidic LC-MS/MS: comparison of DBS and VAMS [Paper presentation]. 42nd International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC), Geneva, Switzerland.

Houbart, V., COBRAIVILLE, G., Servais, A.-C., Napp, A., Merville, M.-P., & Fillet, M. (2015). Hepcidin determination in dried blood by microfluidic LC-MS/MS: comparison of DBS and volumetric absorptive microsampling for matrix effect and recovery. Bioanalysis, 7 (21), 2789-99. doi:10.4155/bio.15.181

Lamalle, C., Roland, D., Crommen, J., Servais, A.-C., & Fillet, M. (2015). Separation of human, bovine, and porcine insulins, three very closely related proteins, by micellar electrokinetic chromatography. Electrophoresis, 36 (19), 2504-6. doi:10.1002/elps.201500178

Lamalle, C., Servais, A.-C., RADERMECKER, R., Crommen, J., & Fillet, M. (2015). Simultaneous determination of insulin and its analogues in pharmaceutical formulations by micellar electrokinetic chromatography. Journal of Pharmaceutical and Biomedical Analysis. doi:10.1016/j.jpba.2014.12.038

Fettweis, G., Coupienne, I., Fillet, M., Lassence, C., Di Valentin, E., & Piette, J. (October 2014). TSC2 and 14-3-3 proteins down-regulate a RIP3 dependent PDT-induced Necroptosis in Glioblastoma [Poster presentation]. Keystone Symposia : "Cell death Signaling in Cancer and the Immune System".

De Bock, M., BEGUIN, Y., Leprince, P., WILLEMS, E., BARON, F., Deroyer, C., Seidel, L., CAVALIER, E., DE SENY, D., MALAISE, M., GOTHOT, A., MERVILLE, M.-P., & Fillet, M. (July 2014). Comprehensive plasma profiling for the characterization of graft-versus-host disease biomarkers. Talanta, 125, 265-275. doi:10.1016/j.talanta.2014.03.017

LE GOFF, C., Devaux, S., BREVERS, E., PEETERS, S., Kaux, J.-F., Fillet, M., Mélon, P., & Cavalier, E. (July 2014). Galectin-3: a new promising cardiac biomarker in sports endurance? Cardiovascular Research, 103 (Supplement 1), 255.

Bettonville, V., Bastin, R., Thelen, N., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (25 June 2014). Study of virus-like particles of human papillomavirus (HPV-VLP) by capillary electrophoresis [Paper presentation]. Drug Analysis 2014.

Farcas, E., Servais, A.-C., Lamalle, C., CHIAP, P., & Fillet, M. (22 June 2014). DEVELOPMENT OF AN ELECTROPHORETICALLY MEDIATED MICROANALYSIS FOR THE IN-LINE METABOLISM STUDY OF 7-ETHOXYCOUMARIN [Poster presentation]. 10th International Symposium on Drug Analysis - 25th International Symposium on Pharmaceutical and Biomedical Analysis, Liege, Belgium.

Houbart, V., Charlier, T., Pawluski, J., Servais, A.-C., & Fillet, M. (June 2014). Fluoxetine and norfluoxetine quantitation in rat serum by LC-chip-MS/MS [Poster presentation]. Drug Analysis 2014.

Houbart, V., Servais, A.-C., & Fillet, M. (June 2014). Quantitation of hepcidin in dried blood spots by microfluidic LC-chip-MS/MS [Paper presentation]. Drug Analysis 2014.

Napp, A., Garraux, G., Servais, A.-C., Merville, M.-P., & Fillet, M. (June 2014). EVALUATION OF α-SYNUCLEIN AS BIOMARKER OF PARKINSON'S DISEASE [Poster presentation]. 10th International Symposium on Drug Analysis.

Lamalle, C., Baptiste, E., Marini Djang'Eing'A, R., Crommen, J., Hubert, P., Servais, A.-C., & Fillet, M. (May 2014). Développement de méthodes séparatives pour détecter la contrefaçon de molécules biosynthétiques comme l'insuline et les GHRP. Spectra Analyse, 43, 47-50.

LE GOFF, C., Kaux, J.-F., Fillet, M., MELON, P., & Cavalier, E. (April 2014). Two biomarkers for the screening of cardiac risk among runners ? British Journal of Sports Medicine, 48 (7), 174.

LE GOFF, C., Kaux, J.-F., Fillet, M., MELON, P., & Cavalier, E. (April 2014). Cardiac troponins and natriuretic peptides in runners: useful for cardiac risk screening ? British Journal of Sports Medicine, 48 (7), 173. doi:10.1136/bjsports-2014-093494.173

Farcas, E., & Fillet, M. (20 January 2014). Thrombosis prevention without bleeding: myth or reality? Development of selective inhibitors of FXIIa [Paper presentation]. Forum des jeunes chercheurs, Liege, Belgium.

Deroyer, C., Renert, A.-F., Merville, M.-P., & Fillet, M. (2014). New role for Emerin, a key inner nuclear membrane protein, as an enhancer of the autophagosome formation in the C16-ceramide autophagy pathway. Autophagy. doi:10.4161/auto.28777

Fillet, M. (2014). Avancées récentes en métabolomique et protéomique [Paper presentation]. Séance publique ordinaire de l'Académie Royale de Médecine de Belgique, Bruxelles, Belgium.

Fradi, I., Farcas, E., Said, A. B., Yans, M.-L., Lamalle, C., Somsen, G. W., Prior, A., de Jong, G. J., Kallel, M., Crommen, J., Servais, A.-C.* , & Fillet, M.*. (2014). In-capillary derivatization with (-)-1-(9-fluorenyl)ethyl chloroformate as chiral labeling agent for the electrophoretic separation of amino acids. Journal of Chromatography. A, 1363, 338-47. doi:10.1016/j.chroma.2014.07.022

Houbart, V., Lecomte, F., COBRAIVILLE, G., Crommen, J., Hubert, P., & Fillet, M. (2014). Influence of sample and mobile phase composition on peptide retention behavior and detector response in miniaturized LC-MS [Poster presentation]. Hyphenated Techniques in Chromatography and Separation Technology 2014.

Lamalle, C., Servais, A.-C., Crommen, J., & Fillet, M. (2014). Micellar electrokinetic chromatography against the counterfeiting of insulin formulations [Poster presentation]. 10th International Symposium on Drug Analysis 25th International Symposium on Pharmaceutical and Biomedical Analysis.

Pawluski, J., van Donkelaar, E., Abrams, Z., Houbart, V., Fillet, M., Steinbusch, H. W. M., & Charlier, T. (2014). Fluoxetine dose and administration method differentially affect hippocampal plasticity in adult female rats. Neural Plasticity, 2014, 123026. doi:10.1155/2014/123026

Servais, A.-C., Moldovan, R.-C., Farcas, E., Crommen, J., ROLAND, I., & Fillet, M. (2014). Development and validation of a liquid chromatographic method for the stability study of a pharmaceutical formulation containing voriconazole using cellulose tris(4-chloro-3-methylphenylcarbamate) as chiral selector and polar organic mobile phases. Journal of Chromatography. A, 1363, 178-82. doi:10.1016/j.chroma.2014.06.082

Houbart, V., Rozet, E., Matagne, A., Crommen, J., Servais, A.-C., & Fillet, M. (01 November 2013). Influence of sample and mobile phase composition on peptide retention behaviour and sensitivity in reversed-phase liquid chromatography/mass spectrometry. Journal of Chromatography. A, 1314, 199-207. doi:10.1016/j.chroma.2013.09.036

Napp, A., Garraux, G., Servais, A.-C., Merville, M.-P., & Fillet, M. (17 October 2013). EVALUATION OF α-SYNUCLEIN AS BIOMARKER OF PARKINSON'S DISEASE [Paper presentation]. 17th Forum of Pharmaceutical Sciences, Spa, Belgium.

Fettweis, G., Coupienne, I., Fillet, M., & Piette, J. (04 September 2013). Role of RIP3 in PDT-induced glioblastoma Cell Death [Poster presentation]. 15th Congress of the European Society for Photobiology, Liège, Belgium.

LE GOFF, C., Kaux, J.-F., MELON, P., Fillet, M., CHAPELLE, J.-P., & Cavalier, E. (September 2013). Running races: study of the stress and cardiac biomarkers. European Journal of Sports Medicine, 1 (Supplement 1), 212.

Houbart, V., Rozet, E., Crommen, J., Servais, A.-C., & Fillet, M. (June 2013). Développement de méthodes de quantification en milieu complexe par chromatographie liquide microfluidique couplée à la spectrometrie de masse [Paper presentation]. 10ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages, Paris, France.

Lamalle, C., Sacre, P.-Y., Marini Djang'Eing'A, R., Servais, A.-C., Hubert, P., Fillet, M., & Crommen, J. (June 2013). ANALYTICAL STRATEGIES FOR THE DETECTION AND CHARACTERIZATION OF COUNTERFEIT MEDICINES [Paper presentation]. 24th Symposium on Pharmaceutical and Biomedical Analysis (PBA2013) / RDPA 2013, Bologna, Italy.

Lamalle, C., Servais, A.-C., Crommen, J., & Fillet, M. (June 2013). L’électrophorèse capillaire micellaire pour la détermination simultanée de l’insuline et de ses analogues dans des formulations pharmaceutiques [Poster presentation]. SEP 2013 10ème congrès francophone sur les sciences séparatives.

LE GOFF, C., MELON, P., BREVERS, E., Fillet, M., Kaux, J.-F., Chapelle, J.-P., & Cavalier, E. (2013). Comparison of the Heart-type fatty acid-binding protein (H-FABP) with the high sensitive cardiac troponin T in healthy runners. In Book of abstracts of 18th Annual Congress of the ECSS (pp. 465).

Servais, A.-C., Moldovan, R.-C., Farcas, E., ROLAND, I., & Fillet, M. (June 2013). DEVELOPMENT AND VALIDATION OF A LC METHOD FOR THE STABILITY STUDY OF A PHARMACEUTICAL FORMULATION CONTAINING VORICONAZOLE USING CELLULOSE TRIS(4-CHLORO-3-METHYLPHENYLCARBAMATE) AS CHIRAL SELECTOR AND POLAR NON-AQUEOUS MOBILE PHASE [Poster presentation]. 39th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Amsterdam, Netherlands.

Napp, A., & Fillet, M. (23 May 2013). Les biomarqueurs de la maladie de Parkinson [Paper presentation]. Séminaire du Centre Interfacultaire de Recherche du Médicament (C.I.R.M), Liege, Belgium.

LE GOFF, C., Kaux, J.-F., BREVERS, E., Fillet, M., MELON, P., CHAPELLE, J.-P., & Cavalier, E. (May 2013). Comparison of the Heart-type fatty acid-binding protein (H-FABP) with the high sensitive cardiac troponin T in healthy runners. Biochimica Clinica, 37 (SS), 544.

LE GOFF, C., Kaux, J.-F., MELON, P., Fillet, M., CHAPELLE, J.-P., & Cavalier, E. (May 2013). Race Cycling: biological evolution. Biochimica Clinica, 37 (SS), 544.

LE GOFF, C., MELON, P., Kaux, J.-F., Fillet, M., CHAPELLE, J.-P., & Cavalier, E. (May 2013). Impact of strenuous exercise on the release of cardiac biomarkers. Biochimica Clinica, 37 (SS), 545.

Marini Djang'Eing'A, R., Fillet, M., Vancauwenberghe, R., Crommen, J., Frederich, M., & Hubert, P. (24 April 2013). Falsification des médicaments: mythe ou réalité ? [Paper presentation]. Cours-conférences 2013 Sciences Biologiques et Médicales, Namur, Belgium.

Esters, V., Karangwa, C., Tits, M., Francotte, P., Pirotte, B., Servais, A.-C., Fillet, M., Crommen, J., Robbrecht, E., MINET, A., Grisar, T., Angenot, L., & Frederich, M. (March 2013). Unusual Amino Acids and Monofluoroacetate from Dichapetalum michelsonii (Umutambasha), a Toxic Plant from Rwanda. Planta Medica, 79, 334-337. doi:10.1055/s-0032-1328283

Crommen, J., Houbart, V., Servais, A.-C., & Fillet, M. (2013). Quantification of fluoxetine and norfluoxetine by HPLC-Chip/MS2 [Paper presentation]. 11th Annual Congress of International Drug Discovery Science and Technology (IDDST), Haikou, Hainan, China.

Crommen, J., Servais, A.-C., Rousseau, A., & Fillet, M. (2013). Fast method development for chiral separations by non-aqueous capillary electrophoresis (NACE) [Paper presentation]. 2nd Annual Conference and Exposition of Analytics (AnalytiX), Suzhou, Jiansu, China.

De Bock, M., Fillet, M., Hannon, M., Seidel, L., Merville, M.-P., Gothot, A., Beguin, Y., & Baron, F. (2013). Kinetics of IL-7 and IL-15 Levels after Allogeneic Peripheral Blood Stem Cell Transplantation following Nonmyeloablative Conditioning. PLoS ONE, 8 (2), 55876. doi:10.1371/journal.pone.0055876

Fillet, M., Deroyer, C., COBRAIVILLE, G., LE GOFF, C., Cavalier, E., Chapelle, J.-P., Marée, R., Legrand, V., Pierard, L., Kolh, P., & Merville, M.-P. (2013). Identification of protein biomarkers associated with cardiac ischemia by a proteomic approach. Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals, 18 (7), 614-24. doi:10.3109/1354750X.2013.838306

Fradi, I., Lamalle, C., Kallel, M., Crommen, J., Servais, A.-C., & Fillet, M. (2013). Amino acids chiral separation by capillary electrophoresis with in-capillary sample preconcentration and chemical derivatisation [Paper presentation]. 29th International Symposium on Microscale Bioseparations (MSB), Charlottesville, VA, United States.

Houbart, V., Servais, A.-C., Crommen, J., & Fillet, M. (2013). Peptide behaviour in RP-HPLC coupled to MS: practical considerations based on a quantitative structure-retention relationship study [Paper presentation]. 39th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC), Amsterdam, Netherlands.

Houbart, V., Servais, A.-C., Crommen, J., & Fillet, M. (2013). Influence of sample and mobile phase composition on peptide retention behaviour and detector response in LC-MS [Paper presentation]. 40th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC), Hobart, Tasmania, Australia.

Knaepen, L., Rayen, I., Charlier, T., Fillet, M., Houbart, V., van Kleef, M., Steinbusch, H. W., Patijn, J., Tibboel, D., Joosten, E. A., & Pawluski, J. (2013). Developmental fluoxetine exposure normalizes the long-term effects of maternal stress on post-operative pain in Sprague-Dawley rat offspring. PLoS ONE, 8 (2), 57608. doi:10.1371/journal.pone.0057608

Lamalle, C., Servais, A.-C., Crommen, J., & Fillet, M. (2013). Simultaneous determination of insulin and its analogues in pharmaceutical formulations by micellar electrokinetic chromatography (MEKC) [Poster presentation]. 24th INTERNATIONAL SYMPOSIUM ON PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, Bologna, Italy.

Nistor, I., Lebrun, P., Ceccato, A., Lecomte, F., Slama, I., Oprean, R., Badarau, E., Dufour, F., Dossou, K. S. S., Fillet, M., Liégeois, J.-F., Hubert, P., & Rozet, E. (2013). Implementation of a Design Space Approach for Enantiomeric Separations in Polar Organic Solvent Chromatography. Journal of Pharmaceutical and Biomedical Analysis, 74, 273-283. doi:10.1016/j.jpba.2012.10.015

Pochet, L.* , Servais, A.-C.* , Farcas, E., Bettonville, V., Bouckaert, C., & Fillet, M. (2013). Determination of inhibitory potency of argatroban toward thrombin by electrophoretically mediated microanalysis. Talanta, 116, 719-725. doi:10.1016/j.talanta.2013.07.030

Servais, A.-C., & Fillet, M. (2013). Enantioseparations in nonaqueous capillary electrophoresis using charged cyclodextrins. In Methods in Molecular Biology 970: Chiral Separations (pp. 297-305). United States: Springer. doi:10.1007/978-1-62703-263-6_19

Servais, A.-C., & Fillet, M. (2013). Application of dual cyclodextrin systems in capillary electrophoresis enantioseparations. In Methods in Molecular biology 970: Chiral Separations (pp. 289-95). United States: Springer. doi:10.1007/978-1-62703-263-6_18

Houbart, V., COBRAIVILLE, G., Servais, A.-C., & Fillet, M. (November 2012). Development of a nano liquid chromatography on chip tandem mass spectrometry method for the quantitation of hepcidin biomarker in biological fluids [Paper presentation]. BIT’s 3rd Annual World Congress of Nanomedicine-2012, Shenzhen, China.

Kohn, G., Delvaux, D., Lakaye, B., Servais, A.-C., Scholer, G., Fillet, M., Elias, B., Derochette, J.-M., Crommen, J., Wins, P., & Bettendorff, L. (12 September 2012). High inorganic triphosphatase activities in bacteria and mammalian cells: Identification of the enzymes involved. PLoS ONE, 7 (9), 43879. doi:10.1371/journal.pone.0043879

Lamalle, C., Marini Djang'Eing'A, R., Debrus, B., Lebrun, P., Crommen, J., Hubert, P., Servais, A.-C., & Fillet, M. (07 August 2012). Development of a generic micellar electrokinetic chromatography method for the separation of 15 antimalarial drugs as a tool to detect medicine counterfeiting. Electrophoresis, 33, 1669-1678. doi:10.1002/elps.201100621

Close, P., Gillard, M., Ladang, A., Jiang, Z., Papuga, J., Hawkes, N., Nguyen, L., CHAPELLE, J.-P., Bouillenne, F., Svejstrup, J., Fillet, M., & Chariot, A. (2012). DERP6 (ELP5) and C3ORF75 (ELP6) regulate tumorigenicity and migration of melanoma cells as subunits of Elongator. Journal of Biological Chemistry. doi:10.1074/jbc.M112.402727

LE GOFF, C., Kaux, J.-F., Goffaux, S., COUFFIGNAL, V., Coubard, R., LAURENT, T., MELON, P., Fillet, M., & Chapelle, J.-P. (2012). Race cycling: biological evolution. In R. Meeusen, J. Duchateau, B. Roelands, M. Klass, B. De Geus, S. Baudry, ... E. Tsolakidis (Eds.), Book of Abstracts of the 17th annual Congress of the ECSS (pp. 245). ECSS.

LE GOFF, C., MELON, P., Kaux, J.-F., Fillet, M., & Chapelle, J.-P. (2012). Impact of strenous exercise on the release of cardiac biomarkers. In R. Meeusen, J. Duchateau, B. Roelands, M. Klass, B. De Geus, S. Baudry, ... E. Tsolakidis (Eds.), Book of Abstracts of the 17th annual Congress of the ECSS (pp. 36). ECSS.

Grammenos, A., Fillet, M., Collodoro, M., Lecart, S., Quoilin, C., Fontaine-Aupart, M.-P., & Hoebeke, M. (2012). An ESR, Mass Spectrometry and Fluorescence microscopy approach to study the stearic acid derivatives anchoring in cells. Applied Magnetic Resonance. doi:10.1007/s00723-012-0375-0

DEROYER, C., Renert, A.-F., Merville, M.-P., & Fillet, M. (25 May 2012). Identification of new emerin partners in ceramide signalling pathway [Paper presentation]. Belgian Society of Biochemistry and Molecular Biology: Proteomics and interactomics in signaling networks.

LE GOFF, C., Kaux, J.-F., Goffaux, S., MELON, P., Fillet, M., & Chapelle, J.-P. (2012). Biological variations during a race cycling. In Biomedica 2012 (pp. 157).

Chankvetadze, L., Servais, A.-C., Fillet, M., Salgado, A., Crommen, J., & Chankvetadze, B. (2012). Comparative enantioseparation of talinolol in aqueous and non-aqueous capillary electrophoresis and study of related selector-selectand interactions by nuclear magnetic resonance spectroscopy. Journal of Chromatography. A, 1267, 206-16. doi:10.1016/j.chroma.2012.08.063

Crommen, J., Dossou, K. S. S., Farcas, E., Servais, A.-C., & Fillet, M. (2012). HPLC separation and determination of drug enantiomers using chlorine-containing cellulose-based chiral stationary phases and polar organic mobiles phases [Paper presentation]. 10th Annual Congress of International Drug Discovery Science and Technology (IDDST), Nanjing, Jiangsu, China.

Crommen, J., Houbart, V., Servais, A.-C., & Fillet, M. (2012). High sensitivity plasma determination of hepcidin, a peptide biomarker for iron metabolism, using HPLC-Chip-ESI-MS [Paper presentation]. 5th Annual Congress and Exposition of Molecular Diagnostics (CEMD), Guangzhou, Guangdong, China.

Dossou, K. S. S., Farcas, E., Servais, A.-C., CHIAP, P., Chankvetadze, B., Crommen, J., & Fillet, M. (2012). Optimization of the liquid chromatography enantioseparation of chiral acidic compounds using cellulose tris(3-chloro-4-methylphenylcarbamate) as chiral selector and polar organic mobile phases. Journal of Chromatography. A, 1234, 56-63. doi:10.1016/j.chroma.2012.01.072

Fradi, I., Servais, A.-C., Lamalle, C., Kallel, M., Abidi, M., Crommen, J., & Fillet, M. (2012). Chemo- and enantio-selective method for the analysis of amino acids by capillary electrophoresis with in-capillary derivatization. Journal of Chromatography. A, 1267, 121-6. doi:10.1016/j.chroma.2012.05.098

Houbart, V., Servais, A.-C., Charlier, T., Pawluski, J., Abts, F., & Fillet, M. (2012). A validated microfluidics-based LC-chip-MS/MS method for the quantitation of fluoxetine and norfluoxetine in rat serum. Electrophoresis. doi:10.1002/elps.201200168

Houbart, V., Servais, A.-C., Crommen, J., & Fillet, M. (2012). Microfluidics-based LC-CHIP-MS/MS method for fluoxetine and norfluoxetine in rat serum [Paper presentation]. 16th Forum of Pharmaceutical Sciences, Blankenberge, Belgium.

Houbart, V., Servais, A.-C., Crommen, J., & Fillet, M. (2012). Development of LC-chip-nano-ESI-MS/MS methods for high sensitivity quantitation in complex matrix [Paper presentation]. 27th International symposium on Microscale Bioseparations and Analysis (MSB 2012), Geneva, Switzerland.

Houbart, V., Servais, A.-C., Crommen, J., & Fillet, M. (2012). Development and validation a LC-chip-MS/MS method for the quantitation of fluoxetine and norfluoxetine in rat serum [Poster presentation]. 19th International Symposium, Exhibit & Workshops on Electro- and Liquid Phase-separation Techniques, Baltimore, United States - Maryland.

Lamalle, C., Servais, A.-C., Crommen, J., & Fillet, M. (2012). Migration behaviour study of charged and uncharged compounds in micellar electrokinetic chromatography systems containing various proportions of SDS micelles and acetonitrile as organic modifier [Poster presentation]. 27th International Symposium on MicroScale Bioseparations and Analyses, Genève, Switzerland.

Lamalle, C., Servais, A.-C., Fradi, I., Crommen, J., & Fillet, M. (2012). Micellar electrokinetic chromatography systems for the separation of mixtures of charged and uncharged compounds. Journal of Separation Science, 35 (15), 1933-1939. doi:10.1002/jssc.201200293

Lamalle, C., Servais, A.-C., Fradi, I., Crommen, J., & Fillet, M. (2012). Micellar electrokinetic chromatography (MEKC) systems for the separation of mixtures of charged and uncharged compounds [Poster presentation]. 19th International Symposium on Electro- and Liquid Phase-separation Techniques (ITP), Baltimore, United States.

Lecat, A., Di Valentin, E., Somja, J., Jourdan, S., Fillet, M., Kufer, T., Habraken, Y., Sadzot-Delvaux, C., Louis, E., Delvenne, P., Piette, J., & Legrand-Poels, S. (2012). The c-jun N-terminal Kinase (JNK)-binding Protein (JNKBP1) Acts as a Negative Regulator of NOD2 Protein Signaling by Inhibiting Its Oligomerization Process. Journal of Biological Chemistry, 287 (35), 29213-26. doi:10.1074/jbc.M112.355545

Nesseim, T. D. T., Fillet, M., Mergeai, G., Dieng, A., & Hornick, J.-L. (2012). Principes toxiques, toxicité et technologie de détoxification de la graine de Jatropha curcas L. (synthèse bibliographique). Biotechnologie, Agronomie, Société et Environnement, 16 (4), 531-540.

Pawluski, J., Charlier, T., Fillet, M., Houbart, V., Crispin, H., Steinbusch, H., & van den Hove, D. (2012). Chronic fluoxetine treatment and maternal adversity differentially alter neurobiohavioral outcomes in rat dam. Behavioural Brain Research. doi:10.1016/j.bbr.2011.11.043

Servais, A.-C., Fillet, M., Chankvetadze, B., & Crommen, J. (2012). Comparative enantioseparation of chiral drug compounds with different cyclodextrins in aqueous and non-aqueous CE and study of related selector-solute interactions by NMR spectroscopy [Paper presentation]. 19th International Symposium on Electro- and Liquid Phase-separation Techniques (ITP), Baltimore, MA, United States.

Servais, A.-C., Rousseau, A., Dive, G., Frederich, M., Crommen, J., & Fillet, M. (2012). Combination of capillary electrophoresis, molecular modelling and nuclear magnetic resonance to study the interaction mechanisms between single-isomer anionic cyclodextrin derivatives and basic drug enantiomers in a methanolic background electrolyte. Journal of Chromatography. A, 1232, 59-64. doi:10.1016/j.chroma.2011.10.010

Houbart, V., COBRAIVILLE, G., Lecomte, F., Debrus, B., Hubert, P., & Fillet, M. (16 December 2011). Development of a nano-liquid chromatography on chip tandem mass spectrometry method for high-sensitivity hepcidin quantitation. Journal of Chromatography. A, 1218 (50), 9046-9054. doi:10.1016/j.chroma.2011.10.030

Lamalle, C., Marini Djang'Eing'A, R., Debrus, B., Lebrun, P., Crommen, J., Hubert, P., Servais, A.-C., & Fillet, M. (September 2011). GENERIC MEKC METHOD FOR THE SEPARATION OF 15 ANTIMALARIAL DRUGS [Poster presentation]. Recent Development in Pharmaceutical Analysis (RDPA), Pavia, Italy.

Marini Djang'Eing'A, R., Mbinze Kindenge, J., Debrus, B., Lebrun, P., Mantanus, J., Ziemons, E., Lamalle, C., Fillet, M., Rudaz, S., & Hubert, P. (September 2011). IMPLEMENTATION OF GENERIC ANALYTICAL METHODS TO FIGHT AGAINST COUNTERFEIT MEDICINES [Paper presentation]. Recent Development in Pharmaceutical Analysis (RDPA), Pavia, Italy.

Mansion, F., Chiap, P., Houbart, V., Crommen, J., Servais, A.-C., & Fillet, M. (July 2011). Optimization of micro-HPLC peak focusing for the detection and quantification of low hepcidin concentrations. Journal of Separation Science, 34 (15), 1820-1827. doi:10.1002/jssc.201100244

Houbart, V., Lecomte, F., COBRAIVILLE, G., Servais, A.-C., Hubert, P., & Fillet, M. (20 June 2011). Development and Prevalidation of a Nano-LC-Chip-MS/MS Method for High Sensitivity Hepcidin Quantitation [Poster presentation]. 36th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Budapest, Hungary.

Lamalle, C., Marini Djang'Eing'A, R., Debrus, B., Lebrun, P., Servais, A.-C., Crommen, J., Hubert, P., & Fillet, M. (June 2011). Development of a Generic MEKC Method for the Separation of 15 Antimalarial Drugs by a Design Space Approach [Poster presentation]. 36th International symposium on HPLC and Related Techniques, Budapest, Hungary.

Servais, A.-C., Rousseau, A., Dive, G., Frederich, M., Crommen, J., & Fillet, M. (June 2011). Combination of capillary electrophoresis, molecular modelling and nuclear magnetic resonance to study the interaction mechanisms between single-isomer anionic CD derivatives and basic drug enantiomers in a methanolic background electrolyte [Poster presentation]. 36th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2011), Budapest, Hungary.

Ziemons, E., Frederich, M., Fillet, M., Hubert, P., & Quetin-Leclercq, J. (May 2011). Espectroscopia aplicada [Paper presentation]. Maestra en Ciencia y Tecnologia de Productos Naturales, Cochabamba, Bolivia.

Servais, A.-C., Rousseau, A., Dive, G., Frederich, M., Pirotte, B., Crommen, J., & Fillet, M. (23 March 2011). Systèmes génériques pour la séparation d’énantiomères de molécules basiques et acides à l’aide de cyclodextrines en électrophorèse capillaire en milieu non aqueux [Paper presentation]. 9ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages (SEP 11), Toulouse, France.

Close, P., Gillard, M., Ladang, A., Jiang, Z., Fillet, M., & Chariot, A. (12 March 2011). DERP6 and C3orf75 regulate the invasive potential of melanoma cells as subunits of the elongator complex [Poster presentation]. Stem Cells, Cancer and Metastasis, United States.

Lecat, A., Di Valentin, E., Fillet, M., Piette, J., & Legrand-Poels, S. (27 January 2011). identification of new parterns of the NOD2 protein [Poster presentation]. cell signalomics 2011, Luxembourg, Luxembourg.

Crommen, J., Rousseau, A., Fradi, I., Servais, A.-C., & Fillet, M. (2011). Enantioseparations in non-aqueous capillary electrophoresis (NACE) [Paper presentation]. 18th International Symposium on Electro- and Liquid Phase-Separation Techniques (ITP), Tbilisi, Georgia.

DE SENY, D., Sharif, M., Fillet, M., COBRAIVILLE, G., Meuwis, M.-A., Marée, R., HAUZEUR, J.-P., Wehenkel, L., Louis, E., Merville, M.-P., Kirwan, J., Ribbens, C., & Malaise, M. (2011). Discovery and biochemical characterisation of four novel biomarkers for osteoarthritis. Annals of the Rheumatic Diseases, 70 (6), 1144-52. doi:10.1136/ard.2010.135541

De Tullio, P., Servais, A.-C., Fillet, M., Gillotin, F., Somers, F., CHIAP, P., Lebrun, P., & Pirotte, B. (2011). Hydroxylated analogues of ATP-sensitive potassium channel openers belonging to the group of 6- and/or 7-substituted 3-Isopropylamino-4H-1,2,4- benzothiadiazine 1,1-dioxides: Toward an improvement in sulfonylurea receptor 1 selectivity and metabolism stability. Journal of Medicinal Chemistry, 54, 8353-8361. doi:10.1021/jm200786z

Dossou, K. S. S., Chiap, P., Chankvetadze, B., Servais, A.-C., Fillet, M., & Crommen, J. (2011). LC enantioseparation of basic pharmaceuticals using chlorine containing cellulose based chiral stationary phases and polar organic mobile phases [Paper presentation]. Recent Development in Pharmaceutical Analysis (RDPA), Pavia, Italy.

Dossou, K. S. S., CHIAP, P., Servais, A.-C., Fillet, M., & Crommen, J. (2011). Evaluation of chlorine containing cellulose-based chiral stationary phases for the LC enantioseparation of basic pharmaceuticals using polar non-aqueous mobile phases. Journal of Separation Science, 34 (6), 617-22. doi:10.1002/jssc.201000774

Dossou, K. S. S., CHIAP, P., Servais, A.-C., Fillet, M., & Crommen, J. (2011). Development and validation of a LC method for the enantiomeric purity determination of S-ropivacaine in a pharmaceutical formulation using a recently commercialized cellulose-based chiral stationary phase and polar non-aqueous mobile phase. Journal of Pharmaceutical and Biomedical Analysis, 54 (4), 687-93. doi:10.1016/j.jpba.2010.10.020

Dossou, K. S. S., Edorh, P. A., Chiap, P., Chankvetadze, B., Servais, A.-C., Fillet, M., & Crommen, J. (2011). Determination of enantiomeric purity of S-amlodipine by chiral LC with emphasis on reversal of enantiomer elution order. Journal of Separation Science, 34, 1772-1780. doi:10.1002/jssc.201100339

Fillet, M. (2011). LC-MS for metabolomics [Paper presentation]. Second Belgian Symposium on Metabolomics and Metabonomics, Liege, Belgium.

Martin, G., Mansion, F., Houbart, V., PAQUET, P., RORIVE, A., CHIAP, P., Crommen, J., Servais, A.-C., & Fillet, M. (2011). Pre-study and in-study validation of a SPE-LC-MS-MS method for the determination of 5-S-cysteinyldopa, a melanoma biomarker, in human plasma. Talanta, 84 (2), 280-6. doi:10.1016/j.talanta.2010.12.047

Quesada Calvo, F.* , Fillet, M.* , Renaut, J., Crahay, C., Guéders, M., Hacha, J., Paulissen, G., Foidart, J.-M., Noël, A., Rocks, N., Leprince, P., & Cataldo, D. (2011). Potential Therapeutic Target Discovery by 2D-DIGE Proteomic Analysis in Mouse Models of Asthma. Journal of Proteome Research, 10 (9), 4291-4301. doi:10.1021/pr200494n

Rousseau, A., Gillotin, F., Chiap, P., Bodoki, E., Crommen, J., Fillet, M., & Servais, A.-C. (2011). Generic systems for the enantioseparation of basic drugs in NACE using single-isomer anionic CDs. Journal of Pharmaceutical and Biomedical Analysis, 54, 154-159. doi:10.1016/j.jpba.2010.08.004

Servais, A.-C., Rousseau, A., CHIAP, P., Fillet, M., & Crommen, J. (2011). Determination of drug enantiomers in various matrices by non-aqueous capillary electrophoresis (NACE) [Paper presentation]. 23rd International Symposium on Pharmaceutical and Biomedical Analysis (PBA), Joao Pessoa PB, Brazil.

Servais, A.-C., Rousseau, A., Fillet, M., & Crommen, J. (2011). Fast method development for the enantioseparation of acidic and basic compounds by non-aqueous capillary electrophoresis (NACE) [Paper presentation]. 17th International Symposium on Separation Sciences (ISSS), Cluj-Napoca, Romania.

Fillet, M., Servais, A.-C., Rousseau, A., Fradi, I., Chankvetadze, B., & Crommen, J. (September 2010). Cyclodextrin-based Chiral Separations by Capillary Electrophoresis in J. Crommen’s lab : a Twenty Years Story [Paper presentation]. Drug Analysis 2010, Antwerp, Belgium.

Fradi, I., Servais, A.-C., Kallel, M., Oueslati, H., Crommen, J., & Fillet, M. (September 2010). Amino acids chiral separation by capillary electrophoresis with in-capillary sample preconcentration and chemical derivatisation [Paper presentation]. Drug Analysis 2010, Antwerp, Belgium.

Houbart, V., Lecomte, F., Cobraiville, G., Crommen, J., Hubert, P., & Fillet, M. (September 2010). A LC-chip nanoelectrospray MS/MS method for hepcidin quantitation in human plasma [Poster presentation]. 9th International Symposium on Drug Analysis - 22nd International Symposium on Pharmaceutical and Biomedical Analysis, Antwerp, Belgium.

Lamalle, C., Marini Djang'Eing'A, R., Debrus, B., Servais, A.-C., Crommen, J., Hubert, P., & Fillet, M. (September 2010). A DESIGN SPACE APPROACH TO DEVELOP A GENERIC CE METHOD FOR THE SEPARATION OF 19 ANTIMALARIAL DRUGS [Poster presentation]. International Symposium on Drug Analysis, Anvers, Belgium.

Servais, A.-C., Rousseau, A., Fillet, M., Lomsadze, K., Salgado, A., Crommen, J., & Chankvetadze, B. (September 2010). Combination of capillary electrophoresis and nuclear magnetic resonance spectroscopy to study the opposite affinity pattern of propranolol enantiomers towards various cyclodextrins [Poster presentation]. Drug Analysis 2010, Anvers, Belgium.

Keutgens, A., Shostak, K., Close, P., Zhang-Shao, X., Hennuy, B., Aussems, M., Chapelle, J.-P., Viatour, P., Gothot, A., Fillet, M., & Chariot, A. (August 2010). The repressing function of the oncoprotein BCL-3 requires CtBP while its polyubiquitination and degradation involve the E3 ligase TBLR1. Molecular and Cellular Biology, 30, 4006-4021. doi:10.1128/MCB.01600-09

Le Goff, C., Garweg, C., Laurent, T., Kaux, J.-F., Deroyer, C., Merville, M.-P., Melon, P., Fillet, M., Legrand, V., & Chapelle, J.-P. (July 2010). Assessment of high sensitive troponin T and I immunoassays in patients with acute chest. Clinical Chemistry, 56 (S6), 127.

Le Goff, C., Laurent, T., Garweg, C., Kaux, J.-F., Deroyer, C., Fillet, M., Lancellotti, P., Pierard, L., & Chapelle, J.-P. (July 2010). Does echocardiographic stress test induced release of hsTnT and TnI II? Clinical Chemistry, 56 (S6), 128.

Rousseau, A., Florence, X., Pirotte, B., Varenne, A., Gareil, P., Villemin, D., Chiap, P., Crommen, J., Fillet, M., & Servais, A.-C. (March 2010). Development and validation of a nonaqueous capillary electrophoretic method for the enantiomeric purity determination of a synthetic intermediate of new R/S-3,4-dihydro-2,2-dimethyl-2H-1-benzopyrans using a single-isomer anionic cyclodextrin derivative and an ionic liquid [Poster presentation]. 25th International Symposium on MicroScale Bioseparations (MSB 2010), Prague, Czechia.

Rousseau, A., Gillotin, F., Chiap, P., Crommen, J., Servais, A.-C., & Fillet, M. (March 2010). Association of two single-isomer anionic CDs in NACE for the chiral and achiral separation of fenbendazole, its sulphoxide and sulphone metabolites: Application to their determination after in vitro metabolism [Poster presentation]. 25th International Symposium on MicroScale Bioseparations (MSB 2010), Prague, Czechia.

Servais, A.-C., Rousseau, A., Chankvetadze, B., Crommen, J., & Fillet, M. (March 2010). Enantioseparation using sulfated beta-cyclodextrins in aqueous and nonaqueous capillary electrophoresis: Study of the mechanisms of enantioselective intermolecular interactions [Poster presentation]. 25th International Symposium on MicroScale Bioseparations (MSB 2010), Prague, Czechia.

Lecat, A., Di Valentin, E., Fillet, M., Rambout, X., Twizere, J.-C., Dequiedt, F., Piette, J., & Legrand-Poels, S. (28 January 2010). NOD2 interactome [Poster presentation]. inflammation 2010, Luxembourg, Luxembourg.

Hubert, C., Houari, S., Lecomte, F., Houbart, V., De Bleye, C., Fillet, M., Piel, G., Rozet, E., & Hubert, P. (26 January 2010). Développement et validation d'une méthode de dosage de la glucosamine par SPE/LC/MS dans le plamsa canin [Paper presentation]. Forum des jeunes chercheurs du C.I.R.M, Liège, Belgium.

Crommen, J., Rousseau, A., Fradi, I., CHIAP, P., Fillet, M., & Servais, A.-C. (2010). Selective determination of drug enantiomers by non-aqueous capillary electrophoresis [Paper presentation]. 14th National Congress of Pharmacy (CNFR), Targu-Mures, Romania.

Crommen, J., Rousseau, A., Fradi, I., Servais, A.-C., & Fillet, M. (2010). L’électrophorèse capillaire: un outil de choix pour l’analyse chirale [Paper presentation]. 3ème Congrès des Sciences Analytiques (CSA), Casablanca, Morocco.

De Bock, M., De Seny, D., Meuwis, M.-A., Servais, A.-C., Minh, T. Q., Closset, J., Chapelle, J.-P., Louis, E., Malaise, M., Merville, M.-P., & Fillet, M. (2010). Comparison of three methods for fractionation and enrichment of low molecular weight proteins for SELDI-TOF-MS differential analysis. Talanta, 82, 245-254. doi:10.1016/j.talanta.2010.04.029

Dossou, K. S. S., Chiap, P., Chankvetadze, B., Servais, A.-C., Fillet, M., & Crommen, J. (2010). Optimization of the LC enantioseparation of chiral pharmaceuticals using cellulose tris(4-chloro-3-methylphenylcarbamate) as chiral selector and polar non-aqueous mobile phases. Journal of Separation Science, 33, 1699-1707. doi:10.1002/jssc.201000049

Hubert, C., Houari, S., Lecomte, F., Houbart, V., De Bleye, C., Fillet, M., Piel, G., Rozet, E., & Hubert, P. (2010). Development and validation of a sensitive solid phase extraction/hydrophilic interaction liquid chromatography/mass spectrometry method for the accurate determination of glucosamine in dog plasma. Journal of Chromatography. A, 1217, 3275-3281. doi:10.1016/j.chroma.2010.01.024

Rousseau, A., Florence, X., Pirotte, B., Varenne, A., Gareil, P., Villemin, D., Chiap, P., Crommen, J., Fillet, M., & Servais, A.-C. (2010). Development and validation of a nonaqueous capillary electrophoretic method for the enantiomeric purity determination of a synthetic intermediate of new 3,4-dihydro-2,2-dimethyl-2H-1-benzopyrans using a single-isomer anionic cyclodextrin derivative and an ionic liquid. Journal of Chromatography. A, 1217 (51), 7949-55. doi:10.1016/j.chroma.2010.07.005

Rousseau, A., Gillotin, F., Chiap, P., Crommen, J., Fillet, M., & Servais, A.-C. (2010). Association of two single-isomer anionic CD in NACE for the chiral and achiral separation of fenbendazole, its sulphoxide and sulphone metabolites: Application to their determination after in vitro metabolism. Electrophoresis, 31, 1482-1487. doi:10.1002/elps.200900723

Rozet, E., Bouabidi, A., Fillet, M., Ziemons, E., Chapuzet, E., Mertens, B., Klinkenberg, R., Ceccato, A., Talbi, M., Streel, B., Bouklouze, A., Boulanger, B., & Hubert, P. (2010). Critical analysis of several analytical method validation strategies in the framework of the fit for purpose concept. Journal of Chromatography. A, 1217, 3180-3192. doi:10.1016/j.chroma.2009.08.051

Servais, A.-C., Crommen, J., & Fillet, M. (2010). Factors Influencing Cyclodextrin-Mediated Chiral Separations. In Chiral Separations by Capillary Electrophoresis (pp. 87-107). Boca Raton, United States - Florida: CRC Press.

Servais, A.-C., Fillet, M., Mol, R., Rousseau, A., Crommen, J., Somsen, G. W., & de Jong, G. J. (2010). Influence of the BGE composition on analyte response in CD-mediated NACE-MS. Electrophoresis, 31 (7), 1157-1161. doi:10.1002/elps.200900649

Servais, A.-C., Rousseau, A., Fillet, M., Lomsadze, K., Salgado, A., Crommen, J., & Chankvetadze, B. (2010). Separation of propranolol enantiomers by CE using sulfated beta-CD derivatives in aqueous and non-aqueous electrolytes: Comparative CE and NMR study. Electrophoresis, 31, 1467-1474. doi:10.1002/elps.200900738

Servais, A.-C., Rousseau, A., Fillet, M., Lomsadze, K., Salgado, A., Crommen, J., & Chankvetadze, B. (2010). Capillary electrophoretic and nuclear magnetic resonance studies on the opposite affinity pattern of propranolol enantiomers towards various cyclodextrins. Journal of Separation Science, 33, 1617-1624. doi:10.1002/jssc.201000040

Hubert, C., Houari, S., Lecomte, F., Houbart, V., De Bleye, C., Fillet, M., Piel, G., Rozet, E., & Hubert, P. (01 December 2009). Développement et validation d'une méthode de dosage de la glucosamine par SPE/HILIC/MS dans le plamsa de chien [Poster presentation]. 8ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages, Marseille, France.

Hubert, C., Houari, S., Houbart, V., De Bleye, C., Fillet, M., Rozet, E., & Hubert, P. (June 2009). Development and validation of a sensitive SPE/LC/MS method for the determination of glucosamine in dog plasma [Poster presentation]. 34th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Dresden, Germany.

Castagne, D., Fillet, M., Delattre, L., Evrard, B., Nusgens, B., & Piel, G. (2009). Study of the cholesterol extraction capacity of β-cyclodextrin and its derivatives, relationships with their effects on endothelial cell viability and on membrane models. Journal of Inclusion Phenomena and Macrocyclic Chemistry, 63 (3-4), 225-231. doi:10.1007/s10847-008-9510-9

Crommen, J., Rousseau, A., Chankvetadze, B., Fillet, M., & Servais, A.-C. (2009). Contribution à l’étude des mécanismes de reconnaissance chirale intervenant lors de la séparation énantiomérique à l’aide de cyclodextrines en électrophorèse capillaire en milieux aqueux et non aqueux [Paper presentation]. 8ème Congrès francophone sur les techniques séparatives et les couplages (SEP'09), Marseille, France.

Crommen, J., Servais, A.-C., Fillet, M., Rousseau, A., Somsen, G. W., & De Jong, G. J. (2009). Influence of the BGE composition on ionization performance in CD mediated NACE-ESI-MS [Paper presentation]. 24th International Symposium on MicroScale Bioseparations (MSB), Dalian, Liaoning, China.

Dahouda, M., Toleba, S. S., Youssao, A. K. I., Hambuckers, A., Dangou-Sapoho, R., Martin, G., Fillet, M., & Hornick, J.-L. (2009). Nutrient digestibility of Mucuna (Mucuna pruriens var. utilis) bean in guinea fowl (Numida meleagris, L): Effects of heat treatment and levels of incorporation in diets. British Poultry Science, 50 (5), 564-72. doi:10.1080/00071660903193774

De Bock, M., De Seny, D., Meuwis, M.-A., Chapelle, J.-P., Louis, E., Malaise, M., Merville, M.-P., & Fillet, M. (2009). Challenges for Biomarker Discovery in Body Fluids Using SELDI-TOF-MS. Journal of Biomedicine and Biotechnology. doi:10.1155/2010/906082

De Bock, M., Merville, M.-P., Fillet, M., & Mansion, F. (Other coll.). (2009). Comparison of sample preparation for fractionation and enrichment of low molecular weight proteins [Poster presentation]. HPLC2009, Dresden, Germany.

De Seny, D., Ribbens, C., Cobraiville, G., Meuwis, M.-A., Marée, R., Geurts, P., Wehenkel, L., Louis, E., Merville, M.-P., Fillet, M., & Malaise, M. (2009). Protéomique par SELDI-TOF-MS des maladies inflammatoires articulaires: identification des protéines S100 comme protéines d'intérêt. Revue Médicale de Liège, 64 (Spec No), 29-35.

Dossou, K. S. S., Chiap, P., Chankvetadze, B., Servais, A.-C., Crommen, J., & Fillet, M. (2009). Evaluation of recently developed cellulose based chiral stationary phases for the LC enantioseparation of basic pharmaceuticals using polar non-aqueous mobile phases [Poster presentation]. 34th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2009), Dresden, Germany.

Dossou, K. S. S., Chiap, P., Chankvetadze, B., Servais, A.-C., Fillet, M., & Crommen, J. (2009). Enantioresolution of basic pharmaceuticals using cellulose tris(4-chloro-3-methylphenylcarbamate) as chiral stationary phase and polar organic mobile phases. Journal of Chromatography. A, 1216 (44), 7450-5. doi:10.1016/j.chroma.2009.05.081

Martin, G., Mansion, F., Servais, A.-C., Debrus, B., Rozet, E., Hubert, P., Crommen, J., & Fillet, M. (2009). CE-MS method development for peptides analysis, especially hepcidin, an iron metabolism marker. Electrophoresis, 30 (15), 2624-31. doi:10.1002/elps.200800794

Quesada Calvo, F.* , Fillet, M.* , De Seny, D., Meuwis, M.-A., Marée, R., Crahay, C., Paulissen, G., Rocks, N., Guéders, M., Wehenkel, L., Merville, M.-P., Louis, R., Foidart, J.-M., Noël, A., & Cataldo, D. (2009). Biomarker discovery in asthma-related inflammation and remodeling. Proteomics, 9 (8), 2163-2170. doi:10.1002/pmic.200800643

Renert, A.-F., Leprince, P., Dieu, M., Renaut, J., Raes, M., Bours, V., Chapelle, J.-P., Piette, J., Merville, M.-P., & Fillet, M. (2009). The proapoptotic C16-ceramide-dependent pathway requires the death-promoting factor Btf in colon adenocarcinoma cells. Journal of Proteome Research, 8 (10), 4810-22. doi:10.1021/pr9005316

Rousseau, A., Chiap, P., Oprean, R., Crommen, J., Fillet, M., & Servais, A.-C. (2009). Effect of the nature of the single-isomer anionic cyclodextrin and the BGE composition on the enantiomeric separation of β-blockers in nonaqueous capillary electrophoresis [Poster presentation]. 34th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2009), Dresden, Germany.

Rousseau, A., Chiap, P., Oprean, R., Crommen, J., Fillet, M., & Servais, A.-C. (2009). Effect of the nature of the single-isomer anionic CD and the BGE composition on the enantiomeric separation of beta-blockers in NACE. Electrophoresis, 30 (16), 2862-8. doi:10.1002/elps.200800824

Rozet, E., Fillet, M., Bouabidi, A., Ziemons, E., Talbi, M., Bouklouze, A., Boulanger, B., & Hubert, P. (2009). Critical analysis of several analytical method validation strategies in the framework of the fit for purpose concept [Poster presentation]. HPLC.

Servais, A.-C., Rousseau, A., CHIAP, P., Fradi, I., Fillet, M., & Crommen, J. (2009). Recent developments in enantioseparations of acidic and basic drug compounds by non-aqueous capillary electrophoresis using charged cyclodextrins as chiral selectors [Paper presentation]. 20th International Symposium on Pharmaceutical and Biomedical Analysis (PBA), Agra, India.

Servais, A.-C., Rousseau, A., Fillet, M., Somsen, G. W., De Jong, G. J., & Crommen, J. (2009). Separation and quantification of low amounts of drug enantiomers using chiral non-aqueous CE with charged cyclodextrins and UV or MS detection [Paper presentation]. 15th Latin American Symposium on Biotechnology, Biomedical, Biopharmaceutical and Industrial Applications of Capillary Electrophoresis and Microchip Technology (LACE), Seville, Spain.

Castagne, D., Fillet, M., Evrard, B., Nusgens, B., & Piel, G. (April 2008). Determination of the ideal cyclodextrin concentrations to study their effect in the lipid rafts by the use of cholesterol extraction and cell viability studies in endothelial cells [Poster presentation]. 6th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Barcelona, Spain.

De Seny, D., Fillet, M., Ribbens, C., Marée, R., Meuwis, M.-A., Lutteri, L., Chapelle, J.-P., Wehenkel, L., Louis, E., Merville, M.-P., & Malaise, M. (2008). Monomeric calgranulins measured by SELDI-TOF mass spectrometry and calprotectin measured by ELISA as biomarkers in arthritis. Clinical Chemistry, 54, 1066-1075. doi:10.1373/clinchem.2007.099549

Dossou, K. S. S., Chiap, P., Servais, A.-C., Fillet, M., & Crommen, J. (2008). Comparison of different cellulose based chiral stationary phases for the LC enantioseparation of basic drugs using polar organic mobile phases [Paper presentation]. 19th International Symposium on pharmaceutical and biomedical analysis (PBA 2008), Gdansk, Poland.

Dossou, K. S. S., Chiap, P., Servais, A.-C., Fillet, M., & Crommen, J. (2008). A screening study of chiral pharmaceuticals using tris(4-chloro-3-methylphenylcarbamate) of cellulose-based stationary phase and polar organic mobile phases [Poster presentation]. 33rd International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2008), Kyoto, Japan.

Meuwis, M.-A., Fillet, M., Chapelle, J.-P., Malaise, M., Louis, E., & Merville, M.-P. (2008). New biomarkers of Crohn's disease: serum biomarkers and development of diagnostic tools. Expert Review of Molecular Diagnostics, 8, 327-37. doi:10.1586/14737159.8.3.327

Meuwis, M.-A.* , Fillet, M.* , Lutteri, L., Marée, R., Geurts, P., De Seny, D., Malaise, M., Chapelle, J.-P., Wehenkel, L., Belaiche, J., Merville, M.-P., & Louis, E. (2008). Proteomics for prediction and characterization of response to infliximab in Crohn's disease: a pilot study. Clinical Biochemistry, 41 (12), 960-7. doi:10.1016/j.clinbiochem.2008.04.021

Rousseau, A., Chiap, P., Ivanyi, R., Crommen, J., Fillet, M., & Servais, A.-C. (2008). Validation of a nonaqueous capillary electrophoretic method for the enantiomeric purity determination of R-flurbiprofen using a single-isomer amino cyclodextrin derivative [Poster presentation]. 22nd International Symposium on MicroScale Bioseparations (MSB 2008), Berlin, Germany.

Rousseau, A., Chiap, P., Ivanyi, R., Crommen, J., Fillet, M., & Servais, A.-C. (2008). Validation of a nonaqueous capillary electrophoretic method for the enantiomeric purity determination of R-flurbiprofen using a single-isomer amino cyclodextrin derivative. Journal of Chromatography. A, 1204 (2), 219-225. doi:10.1016/j.chroma.2008.06.006

Rousseau, A., Pedrini, M., Chiap, P., Ivanyi, R., Crommen, J., Fillet, M., & Servais, A.-C. (2008). Determination of flurbiprofen enantiomers in plasma using a single-isomer amino cyclodextrin derivative in nonaqueous capillary electrophoresis. Electrophoresis, 29 (17), 3641-8. doi:10.1002/elps.200700919

Servais, A.-C., Fillet, M., Rousseau, A., Somsen, G., de Jong, G. J., & Crommen, J. (2008). Influence of the background electrolyte composition and electrospray parameters on the analyte response in cyclodextrin mediated nonaqueous capillary electrophoresis-mass spectrometry [Paper presentation]. 33rd International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2008), Kyoto, Japan.

Castagne, D., Fillet, M., Delattre, L., Evrard, B., Nusgens, B., & Piel, G. (November 2007). Interaction de la b-cyclodextrine et de ses dérivés avec des cellules endothéliales: dosage du cholestérol résiduel [Paper presentation]. 10èmes Journées du Club français des Cyclodextrines, Lens, France.

Castagne, D., Delattre, L., Evrard, B., Fillet, M., Nusgens, B., & Piel, G. (October 2007). Cell membrane destructuration using cyclodextrins: effect on cholesterol content of endothelial cells [Paper presentation]. XIIIth Forum of Pharmaceutical Sciences, Spa, Belgium.

Mol, R., Servais, A.-C., Fillet, M., Crommen, J., de Jong, G. J., & Somsen, G. W. (03 August 2007). Nonaqueous electrokinetic chromatography-electrospray ionization mass spectrometry using anionic cyclodextrins. Journal of Chromatography. A, 1159 (1-2), 51-57. doi:10.1016/j.chroma.2007.05.050

Marini Djang'Eing'A, R., Servais, A.-C., Rozet, E., Chiap, P., Boulanger, B., Rudaz, S., Crommen, J., Hubert, P., & Fillet, M. (June 2007). Enantiomeric purity testing of S-timolol by non-aqueous CE using heptakis(2,3-di-O-methyl-6-O-Sulfo)-β-cyclodextrin as chiral additive – Validation using the accuracy profile strategy and estimation of uncertainty [Poster presentation]. 31st International Symposium on HPLC and Related techniques, Gand, Belgium.

Dossou, K. S. S., Chiap, P., Servais, A.-C., Fillet, M., & Crommen, J. (2007). HPLC enantioseparations of basic drugs using recently developed polysaccharide based chiral stationary phases and polar organic mobile phases [Paper presentation]. 12th International meeting on recent developments in pharmaceutical analysis (RDPA 2007), Elba, Italy.

Dossou, K. S. S., Ghiani, S., Chiap, P., Servais, A.-C., Fillet, M., & Crommen, J. (2007). HPLC enantioseparation of basic pharmaceuticals using a new polysaccharide based chiral stationary phase and non-aqueous polar mobile phases [Poster presentation]. 31st International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2007), Ghent, Belgium.

Mansion, F., Chen, F., Martin, G., Servais, A.-C., Rozet, E., Hubert, P., Crommen, J., & Fillet, M. (2007). Study of the influence of the peak focusing effect in capillary LC columns on detection sensitivity - application to the determination of low concentrations of hepcidine in biofluids [Poster presentation]. 31st international symposium on high performance liquid phase separations and related techniques, Gand, Belgium.

Marini Djang'Eing'A, R., Rozet, E., Vanderheyden, Y., Ziemons, E., Boulanger, B., Bouklouze, A., Servais, A.-C., Fillet, M., Crommen, J., & Hubert, P. (2007). Robustness testing of a chiral NACE method for R-timolol determination in S-timolol maleate and uncertainty assessment from quantitative data. Journal of Pharmaceutical and Biomedical Analysis, 44 (3), 640-51. doi:10.1016/j.jpba.2006.08.018

Martin, G., Chiap, P., Paquet, P., Pierard, G., De Tullio, P., Martin, Y., Rozet, E., Hubert, P., Crommen, J., & Fillet, M. (2007). Development of a mass spectrometry method for the determination of a melanoma biomarker, 5-S-cysteinyldopa, in human plasma using solid phase extraction for sample clean-up. Journal of Chromatography. A, 1156 (1-2), 141-8. doi:10.1016/j.chroma.2006.12.088

Meuwis, M.-A.* , Fillet, M.* , Geurts, P., De Seny, D., Lutteri, L., Chapelle, J.-P., Bours, V., Wehenkel, L., Belaiche, J., Malaise, M., Louis, E., & Merville, M.-P. (2007). Biomarker discovery for inflammatory bowel disease, using proteomic serum profiling. Biochemical Pharmacology, 73 (9), 1422-1433. doi:10.1016/j.bcp.2006.12.019

Rousseau, A., Pedrini, M., Chiap, P., Fillet, M., Crommen, J., & Servais, A.-C. (2007). Determination of flurbiprofen enantiomers in plasma using a single-isomer amino cyclodextrin derivative in non-aqueous capillary electrophoresis [Poster presentation]. 31st International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2007), Ghent, Belgium.

Servais, A.-C., Rousseau, A., Pedrini, M., Crommen, J., & Fillet, M. (2007). Enantioseparation of pharmaceutical compounds using single-isomer cyclodextrin derivatives as chiral additives in nonaqueous capillary electrophoresis [Paper presentation]. 31st International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2007), Ghent, Belgium.

Seumois, G., Fillet, M., Gillet, L., Faccinetto, C., Desmet, C., Francois, C., Dewals, B. G., Oury, C., Vanderplasschen, A., Lekeux, P., & Bureau, F. (2007). De novo C16- and C24-ceramide generation contributes to spontaneous neutrophil apoptosis. Journal of Leukocyte Biology, 81 (6), 1477-1486. doi:10.1189/jlb.0806529

Fradi, I.* , Servais, A.-C.* , Pedrini, M., Chiap, P., Ivanyi, R., Crommen, J., & Fillet, M. (September 2006). Enantiomeric separation of acidic compounds using single-isomer amino cyclodextrin derivatives in nonaqueous capillary electrophoresis. Electrophoresis, 27 (17), 3434-3442. doi:10.1002/elps.200500643

Servais, A.-C., Crommen, J., & Fillet, M. (July 2006). Capillary electrophoresis-mass spectrometry, an attractive tool for drug bioanalysis and biomarker discovery. Electrophoresis, 27 (13), 2616-2629. doi:10.1002/elps.200500934

Marini Djang'Eing'A, R., Rozet, E., Ziemons, E., Chiap, P., Boulanger, B., Rudaz, S., Servais, A.-C., Fillet, M., Crommen, J., & Hubert, P. (May 2006). COMPARISON OF THREE DIFFERENT APPROACHES FOR UNCERTAINTY ESTIMATION CONSIDERING LC AND CE METHODS [Paper presentation]. A joint meeting of two distinguished series: the 8th International Symposium on Drug Analysis and the 17th International Symposium on Pharmaceutical and Biomedical Analysis, Namur, Belgium.

Servais, A.-C.* , Fillet, M.* , Mol, R., Somsen, G. W., Chiap, P., de Jong, G. J., & Crommen, J. (February 2006). On-line coupling of cyclodextrin mediated nonaqueous capillary electrophoresis to mass spectrometry for the determination of salbutamol enantiomers in urine. Journal of Pharmaceutical and Biomedical Analysis, 40 (3), 752-757. doi:10.1016/j.jpba.2005.08.004

Crommen, J., Servais, A.-C., Fradi, I., Chiap, P., & Fillet, M. (2006). Enantiomeric separation of acidic compounds in nonaqueous capillary electrophoresis using single-isomer amino cyclodextrin derivatives as chiral selectors [Paper presentation]. 20th International Symposium on Microscale Bioseparations, Amsterdam, Netherlands.

Crommen, J., Servais, A.-C., Rousseau, A., Fradi, I., Chiap, P., & Fillet, M. (2006). Enantioseparations in nonaqueous capillary electrophoresis using charged cyclodextrin derivatives as chiral selectors [Paper presentation]. 30th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2006), San Francisco, United States.

Fillet, M., Fradi, I., Pedrini, M., Chiap, P., Ivanyi, R., Crommen, J., & Servais, A.-C. (2006). Enantioseparation of nonsteroidal anti-inflammatory drugs using single-isomer amino cyclodextrin derivatives in nonaqueous capillary electrophoresis [Poster presentation]. 20th International Symposium on Microscale Bioseparations, Amsterdam, Netherlands.

Marini Djang'Eing'A, R., Groom, C., Doucet, F. R., Hawari, J., Bitar, Y., Holzgrabe, U., Gotti, R., Schappler, J., Rudaz, S., Veuthey, J.-L., Mol, R., Somsen, G. W., de Jong, G. J., Ha, P. T. T., Zhang, J., Van Schepdael, A., Hoogmartens, J., Brione, W., Ceccato, A., ... Hubert, P. (2006). Interlaboratory study of a NACE method for the determination of R-timolol content in S-timolol maleate: assessment of uncertainty. Electrophoresis, 27 (12), 2386-99. doi:10.1002/elps.200500832

Marini Djang'Eing'A, R.* , Servais, A.-C.* , Rozet, E., Chiap, P., Boulanger, B., Rudaz, S., Crommen, J., Hubert, P., & Fillet, M. (2006). Nonaqueous capillary electrophoresis method for the enantiomeric purity determination of S-timolol using heptakis(2,3-di-O-methyl-6-O-sulfo)-beta-cyclodextrin: validation using the accuracy profile strategy and estimation of uncertainty. Journal of Chromatography. A, 1120 (1-2), 102-11. doi:10.1016/j.chroma.2006.03.104

Martin, G., Chiap, P., Paquet, P., Pierard, G., Hubert, P., Crommen, J., & Fillet, M. (2006). Determination of catecholamines in human plasma using solid phase extraction and LC-ESI-MS-MS [Poster presentation]. Drug Analysis, Namur, Belgium.

Martin, G., Chiap, P., Paquet, P., Pierard, G., Rozet, E., Hubert, P., Crommen, J., & Fillet, M. (2006). Determination of a melanoma biomarker in human plasma the 5-S-cysteinyl-l-dopa by LC-ESI-MS-MS [Paper presentation]. 30rd international symposium on high performance liquid phase separation and related techniques, San Francisco, United States.

Martin, G., Chiap, P., Pierard, G., Hubert, P., Crommen, J., & Fillet, M. (2006). LC-ESI-MS-MS determination of 5-S-L-cysteinyl-L-dopa, a melanoma biomarker, in human plasma [Poster presentation]. Drug Analysis, Namur, Belgium.

Rousseau, A., Fradi, I., Servais, A.-C., Pedrini, M., Ivanyi, R., Fillet, M., & Crommen, J. (2006). Enantiomeric separation of nonsteroidal anti-inflammatory drugs in nonaqueous capillary electrophoresis using single-isomer amino cyclodextrin derivatives [Poster presentation]. Drug Analysis 2006, Namur, Belgium.

Servais, A.-C., Fillet, M., Mol, R., Somsen, G., Chiap, P., de Jong, G. J., & Crommen, J. (2006). Determination of salbutamol enantiomers in urine by nonaqueous capillary electrophoresis-mass spectrometry [Poster presentation]. Drug Analysis 2006, Namur, Belgium.

Tokarski, C., Cren-Olive, C., Fillet, M., & Rolando, C. (2006). High-sensitivity staining of proteins for one- and two-dimensional gel electrophoresis using post migration covalent staining with a ruthenium fluorophore. Electrophoresis, 27 (7), 1407-16. doi:10.1002/elps.200500426

Yi, F., Zhang, A. Y., Li, N., Muh, R. W., Fillet, M., Renert, A.-F., & Li, P.-L. (2006). Inhibition of ceramide-redox signaling pathway blocks glomerular injury in hyperhomocysteinemic rats. Kidney International, 70 (1), 88-96. doi:10.1038/sj.ki.5001517

Crommen, J., Marini Djang'Eing'A, R., Servais, A.-C., Chiap, P., Rozet, E., Hubert, P., & Fillet, M. (June 2005). Validation of a NACE method for the enantiomeric purity determination of S-timolol using heptakis(2,3-di-O-methyl-6-O-sulfo)-B-CD [Paper presentation]. 29th International Symposium on High Perfomance Liquid Phase Separations and Related Techniques, Stockholm, Sweden.

Servais, A.-C., Fillet, M., Chiap, P., Dewé, W., Hubert, P., & Crommen, J. (11 March 2005). Influence of the nature of the electrolyte on the chiral separation of basic compounds in nonaqueous capillary electrophoresis using heptakis(2,3-di-O-methyl-6-O-sulfo)-beta-cyclodextrin. Journal of Chromatography. A, 1068 (1), 143-150. doi:10.1016/j.chroma.2004.12.010

Crommen, J., Servais, A.-C., Fradi, I., Chiap, P., & Fillet, M. (2005). Enantioselective determination of pharmaceutical compounds in biofluids by coupling SPE to non-aqueous CE with charged cyclodextrins as chiral additives [Paper presentation]. 4th International Symposium on Separations in the BioSciences (SBS’05), Utrecht, Netherlands.

Crommen, J., Servais, A.-C., Fradi, I., Fillet, M., & Chiap, P. (2005). Enantioseparation of ionizable compounds in non-aqueous capillary electrophoresis using charged cyclodextrin derivatives as chiral additives [Paper presentation]. 29th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2005), Stockholm, Sweden.

Crommen, J., Servais, A.-C., Fradi, I., Marini Djang'Eing'A, R., Chiap, P., Hubert, P., & Fillet, M. (2005). Enantiomeric separation of acidic and basic chiral drugs in non-aqueous capillary electrophoresis using cyclodextrin with the opposite charge [Paper presentation]. 11th meeting on recent developments in pharmaceutical analysis (RDPA), Rimini, Italy.

De Seny, D.* , Fillet, M.* , Meuwis, M.-A., Geurts, P., Lutteri, L., Ribbens, C., Bours, V., Wehenkel, L., Piette, J., Malaise, M., & Merville, M.-P. (2005). Discovery of new rheumatoid arthritis biomarkers using the surface-enhanced laser desorption/ionization time-of-flight mass spectrometry ProteinChip approach. Arthritis and Rheumatism, 52 (12), 3801-12. doi:10.1002/art.21607

Fillet, M., Cren-Olive, C., Renert, A.-F., Piette, J., Vandermoere, F., Rolando, C., & Merville, M.-P. (2005). Differential expression of proteins in response to ceramide-mediated stress signal in colon cancer cells by 2-D gel electrophoresis and MALDI-TOF-MS. Journal of Proteome Research, 4 (3), 870-80. doi:10.1021/pr050006t

Geurts, P., Fillet, M., De Seny, D., Meuwis, M.-A., Malaise, M., Merville, M.-P., & Wehenkel, L. (2005). Proteomic mass spectra classification using decision tree based ensemble methods. Bioinformatics, 21 (14), 3138-45. doi:10.1093/bioinformatics/bti494

Mol, R., Servais, A.-C., Fillet, M., Crommen, J., De Jong, G. J., & Somsen, G. W. (2005). Coupling of non-aqueous electrokinetic chromatography to electrospray ionization mass spectrometry (NAEKC-ESI-MS) for drug analysis [Poster presentation]. 4th International Symposium on Separations in the BioSciences (SBS’05), Utrecht, Netherlands.

Olivier, S., Fillet, M., Malaise, M., Piette, J., Bours, V., Merville, M.-P., & Franchimont, N. (2005). Sodium nitroprusside-induced osteoblast apoptosis is mediated by long chain ceramide and is decreased by raloxifene. Biochemical Pharmacology, 69 (6), 891-901. doi:10.1016/j.bcp.2004.11.030

Christiaens, B., Fillet, M., Chiap, P., Rbeida, O., Ceccato, A., Streel, B., De Graeve, J., Crommen, J., & Hubert, P. (12 November 2004). Fully automated method for the liquid chromatographic-tandem mass spectrometric determination of cyproterone acetate in human plasma using restricted access material for on-line sample clean-up. Journal of Chromatography. A, 1056 (1-2), 105-110. doi:10.1016/j.chroma.2004.06.107

De Seny, D., Fillet, M., Meuwis, M.-A., Lutteri, L., Geurts, P., Wehenkel, L., Bours, V., Piette, J., Malaise, M., & Merville, M.-P. (September 2004). Discovery of new rheumatoid arthritis biomarkers using SELDI-TOF-MS ProteinChip approach. Arthritis and Rheumatism, 50 (9, Suppl. S), 124.

Servais, A.-C., Fillet, M., Chiap, P., Dewé, W., Hubert, P., & Crommen, J. (August 2004). Enantiomeric separation of basic compounds usin heptakis(2,3-di-O-methyl-6-O-sulfo)-beta-cyclodextrin in combination with potassium camphorsulfonate in nonaqueous capillary electrophoresis: Optimization by means of an experimental design. Electrophoresis, 25 (16), 2701-2710. doi:10.1002/elps.200405962

Servais, A.-C., Chiap, P., Hubert, P., Crommen, J., & Fillet, M. (June 2004). Determination of salbutamol enantiomers in human urine using heptakis(2,3-di-O-acetyl-6-O-sulfo)-beta-cyclodextrin in nonaqueous capillary electrophoresis. Electrophoresis, 25 (10-11), 1632-1640. doi:10.1002/elps.200405854

Marini Djang'Eing'A, R., Boulanger, B., Abushoffa, A., Fillet, M., Chiap, P., Hubert, P., & Crommen, J. (February 2004). ENANTIOMERIC PURITY TESTING OF S-KETOPROFEN IN PHARMACEUTICAL FORMULATIONS BY CE USING A DUAL CYCLODEXTRIN SYSTEM [Poster presentation]. 17th International Symposium on Microscale Separations and Capillary Electrophoresis, Salzburg, Austria.

Christiaens, G., Chiap, P., Fillet, M., Rbeida, O., Ceccato, A., Streel, B., De Graeve, J., Crommen, J., & Hubert, P. (2004). New fully automated method for the LC-MS/MS determination of cyproterone acetate in human plasma using restricted access material for sample clean-up [Poster presentation]. 8th International Symposium on Hyphenated Techniques in Chromatography and Hyphenated Chromatographic Analyzers (HTC-8), Bruges, Belgium.

Christians, B., Fillet, M., Chiap, P., Rbeida, O., Ceccato, A., Streel, B., De Graeve, J., Crommen, J., & Hubert, P. (2004). Fully automated method for the liquid chromatographic-tandem mass spectrometric determination of cyproterone acetate in human plasma using restricted access material for on-line sample clean-up. Journal of Chromatography. A, 1056 (1-2), 105-10.

Crommen, J., Servais, A.-C., Fillet, M., Chiap, P., Dewé, W., & Hubert, P. (2004). Enantiomeric separation of ionisable compounds in non-aqueous capillary electrophoresis using charged cyclodextrins in combination with ion-pairing reagents [Paper presentation]. 25th International Symposium on Chromatography (ISC 04), Paris, France.

Crommen, J., Servais, A.-C., Fillet, M., Chiap, P., Dewé, W., & Hubert, P. (2004). Enantiomeric separation of basic drugs using anionic cyclodextrins in non-aqueous capillary electrophoresis : optimization of the background electrolyte composition [Paper presentation]. 17th International Symposium on Microscale Separations an Capillary Electro-phoresis, Salzburg, Austria.

Crommen, J., Servais, A.-C., Fillet, M., Chiap, P., & Hubert, P. (2004). Enantiomeric separation in non-aqueous capillary electrophoresis using charged cyclodextrins in combination with other ionic additives [Paper presentation]. 15th International Symposium on pharmaceutical and biomedical analysis (PBA), Florence, Italy.

Crommen, J., Servais, A.-C., Fillet, M., & Hubert, P. (2004). Enantioseparation of basic pharmaceuticals in non-aqueous capillary electrophoresis using anionic cyclodextrins as chiral selectors [Paper presentation]. 12th International Cyclodextrin Symposium, Montpellier, France.

Jans, D., Martinet, W., Fillet, M., Kockx, M. M., Merville, M.-P., Bult, H., Herman, A. G., & De Meyer, G. R. Y. (2004). Effect of non-steroidal anti-inflammatory drugs on amyloid-beta formation and macrophage activation after platelet phagocytosis. Journal of Cardiovascular Pharmacology, 43 (3), 462-70. doi:10.1097/00005344-200403000-00019

Servais, A.-C., Fillet, M., Chiap, P., Hubert, P., & Crommen, J. (2004). Validation d’une méthode de dosage des énantiomères du salbutamol dans l’urine par électrophorèse capillaire en milieu non aqueux en utilisant une cyclodextrine anionique comme sélecteur chiral [Poster presentation]. Forum labo et forum biotech, Paris, France.

Servais, A.-C., Fillet, M., Chiap, P., Hubert, P., & Crommen, J. (2004). First application of non-aqueous capillary electrophoresis for the determination of the enantiomers of a basic chiral drug in biological samples: Quantification of salbutamol in human urine [Poster presentation]. 15th International Symposium on pharmaceutical and biomedical analysis (PBA), Florence, Italy.

Servais, A.-C., Fillet, M., Chiap, P., Hubert, P., & Crommen, J. (2004). Determination of salbutamol enantiomers in human urine using anionic cyclo-dextrins in non-aqueous capillary electrophoresis [Poster presentation]. 17th International Symposium on Microscale Separations an Capillary Electro-phoresis, Salzburg, Austria.

Seumois, G., Fillet, M., Gillet, L., Vanderplasschen, A., Lekeux, P., & Bureau, F. (2004). Ceramides play a critical role in spontaneous neutrophil apoptosis. Pflügers Archiv: European Journal of Physiology, 447, 9-25.

Olivier, S., Fillet, M., Malaise, M., Piette, J., Bours, V., Merville, M.-P., & Franchimont, N. (September 2003). Raloxifene protects Osteoblasts from apoptosis induced by sodium nitroprusside: Potential involvement of ceramide. Journal of Bone and Mineral Research, 18 (Suppl. 2), 136.

Fillet, M., Servais, A.-C., & Crommen, J. (May 2003). Effects of background electrolyte composition and addition of selectors on separation selectivity in nonaqueous capillary electrophoresis. Electrophoresis, 24 (10), 1499-1507. doi:10.1002/elps.200305412

Abushoffa, A. M., Fillet, M., Marini Djang'Eing'A, R., Hubert, P., & Crommen, J. (2003). Enantiomeric separation of aminoglutethimide by capillary electrophoresis using native cyclodextrins in single and dual systems. Journal of Separation Science, 26 (6-7), 536-542. doi:10.1002/jssc.200390073

Abushoffa, A. M., Fillet, M., Servais, A.-C., Hubert, P., & Crommen, J. (2003). Enhancement of selectivity and resolution in the enantioseparation of uncharged compounds using mixtures of oppositely charged cyclodextrins in capillary electrophoresis. Electrophoresis, 24 (3), 343-50. doi:10.1002/elps.200390044

Bentires-Alj, M., Barbu, V., Fillet, M., Chariot, A., Relic, B., Jacobs, N., Gielen, J., Merville, M.-P., & Bours, V. (2003). NF-κB transcription factor induces drug resistance through MDR1 expression in cancer cells. Oncogene, 22, 90-97. doi:10.1038/sj.onc.1206056

Crommen, J., Servais, A.-C., Dewé, W., Chiap, P., Fillet, M., & Hubert, P. (2003). Enantiomeric separation of basic pharmaceuticals in non-aqueous capillary electrophoresis using an anionic cyclodextrin in combination with an ion-pairing reagent [Paper presentation]. 3th International Symposium on Separations in Biosciences (SBS 2003), Moscow, Russia.

Crommen, J., Servais, A.-C., Fillet, M., Abushoffa, A., Chiap, P., & Hubert, P. (2003). Modulation of selectivity for the enantiomeric separation of basic compounds in non-aqueous CE using anionic cyclodextrins in combination with ion-pairing re-agents [Paper presentation]. 27th International Symposium on high performance liquid phase separations and related techniques, Nice, France.

Crommen, J., Servais, A.-C., Fillet, M., & Hubert, P. (2003). New approaches for enantiomeric separation in non-aqueous camillary electrophoresis (NACE) [Paper presentation]. 4th International Symposium on Pharmaceutical Chemistry, Istanbul, Turkey.

Fillet, M., Bentires-Alj, M., Deregowski, V., Greimers, R., Gielen, J.-L., Piette, J., Bours, V., & Merville, M.-P. (2003). Mechanisms involved in exogenous C2- and C6-ceramide-induced cancer cell toxicity. Biochemical Pharmacology, 65 (10), 1633-42. doi:10.1016/S0006-2952(03)00125-4

Servais, A.-C., Dewé, W., Chiap, P., Fillet, M., Abushoffa, A., Hubert, P., & Crommen, J. (2003). Separation énatiomérique de substances médicamenteuses basiques par électrophorèse capillarie en milieu non aqueux : effet de l’utilisation simul-tanée d’une cyclodextrine anionique et d’un agent d’appariement d’ions [Paper presentation]. 5e Congrès francophone sur les techniques séparatives et les couplages (SEP 2003), Lyon, France.

Servais, A.-C., Fillet, M., Abushoffa, A. M., Hubert, P., & Crommen, J. (2003). Synergistic effects of ion-pairing in the enantiomeric separation of basic compounds with cyclodextrin derivatives in nonaqueous capillary electrophoresis. Electrophoresis, 24 (3), 363-369. doi:10.1002/elps.200390046

Seumois, G., Fillet, M., Gillet, L., Vanderplasschen, A., Lekeux, P., & Bureau, F. (2003). Ceramides play a critical role in spontaneous neutrophil apoptosis [Poster presentation]. Autumn Meeting of the Belgian Society of Fundamental and Clinical Physiology and Pharmacology, Liège, Belgium.

Servais, A.-C., Fillet, M., Chiap, P., Abushoffa, A. M., Hubert, P., & Crommen, J. (December 2002). Optimization of the separation of beta-blockers by ion-pair capillary electrophoresis in non-aqueous media using univariate and multivariate approaches. Journal of Separation Science, 25 (15-17), 1087-1095. doi:10.1002/1615-9314(20021101)25:15/17<1087::AID-JSSC1087>3.0.CO;2-A

Abushoffa, A., Fillet, M., Hubert, P., & Crommen, J. (2002). Selectivity enhancement for the CE enantioseparation of uncharged compounds using mixtures of cationic and anionic cyclodextrin derivatives [Poster presentation]. 15th International Symposium on Microscale Separations and Analyses (HPCE 2002), Stockholm, Sweden.

Abushoffa, A. M., Fillet, M., Hubert, P., & Crommen, J. (2002). Prediction of selectivity for enantiomeric separations of uncharged compounds by capillary electrophoresis involving dual cyclodextrin systems. Journal of Chromatography. A, 948 (1-2), 321-9. doi:10.1016/S0021-9673(01)01371-1

Abushoffa, A., Fillet, M., Servais, A.-C., Hubert, P., & Crommen, J. (2002). Enantioseparation of uncharged compounds using combinations of octakis-(2,3-dihydroxy-6-sulfato)--cyclodextrin and heptakis-(2,3,6-tri-O-methyl)--cyclodextrin in capillary electrophoresis [Poster presentation]. 26th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2002), Montreal, Canada.

Crommen, J., Abushoffa, A., Fillet, M., & Hubert, P. (2002). The design of dual systems for amplification of selectivity in CE enantioseparations [Paper presentation]. 15th International Symposium on Microscale Separations and Analyses (HPCE 2002), Stockholm, Sweden.

Crommen, J., Servais, A.-C., Abushoffa, A., Fillet, M., & Hubert, P. (2002). Selectivity enhancement in chiral and achiral separations of basic drugs by ion-pairing in non-aqueous capillary electrophoresis [Paper presentation]. 26th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2002), Montreal, Canada.

Fillet, M., Servais, A.-C., Van Heugen, J.-C., De Graeve, J., & Crommen, J. (2002). Identification and quantification of endogenous ceramides in human cancer cells by LC-ESI-MS-MS [Poster presentation]. 7th International Symposium on Drug Analysis, Bruges, Belgium.

Fillet, M., Van Heugen, J.-C., Servais, A.-C., De Graeve, J., & Crommen, J. (2002). Separation, identification and quantitation of ceramides in human cancer cells by liquid chromatography–electrospray ionization tandem mass spectrometry. Journal of Chromatography. A, 949, 225-233. doi:10.1016/S0021-9673(01)01422-4

Servais, A.-C., Fillet, M., Chiap, P., Abushoffa, A., Hubert, P., & Crommen, J. (2002). Multivariate optimization approach for the separation of beta-blockers by ion-pair capillary electrophoresis in non-aqueous media [Poster presentation]. 7th International Symposium on Drug Analysis, Bruges, Belgium.

Abushoffa, A., Fillet, M., Hubert, P., & Crommen, J. (2001). Prediction of selectivity and resolution in enatiomeric separations of uncharged compounds by capillary electrophoresis using dual cyclodextrin systems [Poster presentation]. HPCE 2001, Boston, United States.

Abushoffa, A., Fillet, M., Hubert, P., & Crommen, J. (2001). CE determination of binding constants between profen enantiomers and single-isomer anionic and neutral cyclodextrins [Poster presentation]. HPLC 2001, Maastricht, Netherlands.

Crommen, J., Abushoffa, A., Fillet, M., Chankvetadze, B., & Hubert, P. (2001). The use of two chiral selectors in combination for the enantioseparation of drugs by capillary electrophoresis : benefits and limitations [Paper presentation]. 9th International Meeting on Recent Developments in Pharmaceutical Analysis (RDPA) 2001, Lipari, Aeolian Islands, Messina, Italy.

Crommen, J., Abushoffa, A., Fillet, M., & Hubert, P. (2001). Prédiction de la sélectivité lors de séparations chirales en électrophorèse capillaire à l’aide de mélanges de cyclodextrines (systèmes duaux) [Paper presentation]. SEP 2001, Paris, France.

Crommen, J., Abushoffa, A., Fillet, M., & Hubert, P. (2001). Optimization of the CE enantioseparation of uncharged compounds in dual cyclodextrin systems [Paper presentation]. HPCE 2001, Boston, United States.

Crommen, J., Abushoffa, A., Fillet, M., & Hubert, P. (2001). Modulation of selectivity for enantiomeric separation in CE using mixtures of cationic and anionic cyclodextrins [Paper presentation]. HPLC 2001, Maastricht, Netherlands.

Servais, A.-C., Fillet, M., Hubert, P., & Crommen, J. (2001). Separation of closely related basic drugs by ion-pair capillary electrophoresis in non-aqueous media [Paper presentation]. Forum des Sciences Pharmaceutiques, Montréal, Canada.

Servais, A.-C., Fillet, M., Hubert, P., & Crommen, J. (2001). Separation of beta-blockers by ion-pair capillary electrophoresis in non-aqueous media [Poster presentation]. HPLC 2001, Maastricht, Netherlands.

Fillet, M., Hubert, P., & Crommen, J. (14 April 2000). Enantiomeric Separations of Drugs Using Mixtures of Charged and Neutral Cyclodextrins. Journal of Chromatography. A, 875 (1-2), 123-34. doi:10.1016/S0021-9673(00)00084-4

Abushoffa, A., Fillet, M., Marini Djang'Eing'A, R., & Crommen, J. (07 April 2000). Separation of aminoglutethimide enantiomers using single and dual cyclodextrin system in capillary electrophoresis [Paper presentation]. 9th Forum of Pharmaceutical Sciences, Blankenberge, Belgium.

Abushoffa, A., Fillet, M., Marini Djang'Eing'A, R., Chankvetadze, B., & Crommen, J. (February 2000). Enantiomeric separation of aminoglutethimide by capillary electrophoresis using native cyclodextrins in single and dual systems [Poster presentation]. 13th International Symposium on High Performance Capillary Electrophoresis & Related Microscale Techniques, Saarbrücken, Germany.

Abushoffa, A., Fillet, M., Hubert, P., & Crommen, J. (2000). Separation of aminoglutethimide enantiomers using single and dual cyclodextrin systems in capillary electrophoresis [Paper presentation]. 9e Forum des Sciences Pharmaceutiques, Blankenberge, Belgium.

Chankvetadze, B., Fillet, M., Burjanadze, N., Bergenthal, D., Bergander, C., Luftmann, H., Crommen, J., & Blaschke, G. (2000). Enantioseparation of aminoglutethimide with cyclodextrins in capillary electrophoresis and studies of selector-selectand interactions using NMR spectroscopy and electrospray ionization mass spectrometry. Enantiomer, 5 (3-4), 313-22.

Crommen, J., Abushoffa, A., Fillet, M., & Hubert, P. (2000). Enantiomeric separation of drugs by capillary electrophoresis using dual cyclodextrin systems [Paper presentation]. EUFEPS 2000, Budapest, Hungary.

Crommen, J., Fillet, M., Abushoffa, A., & Hubert, P. (2000). The use of dual cyclodextrin systems for enantiomeric separations in capillary electrophoresis : is it the panacea ? [Paper presentation]. XXIIIrd International Symposium on Capillary Chromatography, Riva del garda, Italy.

Fillet, M., Abushoffa, A., Hubert, P., & Crommen, J. (2000). Model for selectivity optimizations by capillary electrophoresis using dual cyclodextrin systems [Paper presentation]. XIIIth International Symposium on High Performance Capillary Electrophoresis, Saarbrucken, Germany.

Fillet, M., Bechet, I., Fotsing, L., Piette, V., & Crommen, J. (2000). Separation of non-steroidal anti-inflammatory drugs by capillary electrophoresis using non-aqueous electrolyte. Biomedical Chromatography: BMC, 14 (1), 12-3. doi:10.1002/(sici)1099-0801(200002)14:1<12::aid-bmc948>3.0.co;2-%23

Fotsing, L., Boulanger, B., Chiap, P., Fillet, M., Hubert, P., & Crommen, J. (2000). Multivariate optimization approach for the separation of water-soluble vitamins and related compounds by capillary electrophoresis. Biomedical Chromatography: BMC, 14 (1), 10-1. doi:10.1002/(SICI)1099-0801(200002)14:1<10::AID-BMC947>3.0.CO;2-8

Fotsing, L., Fillet, M., Boulanger, B., Chiap, P., Hubert, P., & Crommen, J. (2000). Determination of water-soluble vitamins and related compounds by capillary electrophoresis using a multivariate approach for method development [Poster presentation]. XIIIth International Symposium on High Performance Capillary Electrophoresis, Saarbrucken, Germany.

Piette, V., Fillet, M., Lindner, W., & Crommen, J. (2000). Non-aqueous capillary electrophoretic enantioseparation of N-derivatized amino acids using cinchona alkaloids and derivatives as chiral counter-ions. Journal of Chromatography. A, 875 (1-2), 353-60. doi:10.1016/S0021-9673(00)00083-2

Piette, V., Fillet, M., Lindner, W., & Crommen, J. (2000). Enantiomeric separation of amino acid derivatives by non-aqueous capillary electrophoresis using quinine and related compounds as chiral additives. Biomedical Chromatography: BMC, 14 (1), 19-21. doi:10.1002/(SICI)1099-0801(200002)14:1<19::AID-BMC951>3.0.CO;2-Z

Crommen, J., Fillet, M., Abushoffa, A., Fotsing, L., & Hubert, P. (1999). Design of dual cyclodextrin systems in capillary electrophoresis for selectivity optimisation in enantiomeric separations [Paper presentation]. Balaton Symposium’99, Siofok, Hungary.

Crommen, J., Fillet, M., Abushoffa, A., Fotsing, L., & Hubert, P. (1999). Design of dual cyclodextrin systems in capillary electrophoresis for selectivity optimisation in chiral analysis [Paper presentation]. 8th International Meeting on Recent Development in Pharmaceutical Analysis (RDPA’99), Rome, Italy.

Crommen, J., Fillet, M., Fotsing, L., & Hubert, P. (1999). Method development strategies for enantiomeric separations by capillary electrophoresis using charged and neutral cyclodextrin derivatives as chiral selectors [Paper presentation]. IIIrd Miniaturisation in Liquid Chromatography versus Capillary Electrophoresis Conference, Gent, Belgium.

Crommen, J., Fotsing, L., Fillet, M., Chiap, P., & Hubert, P. (1999). Method development and validation for the CE analysis of multi-vitamin formulations [Paper presentation]. Xth International Symposium on Pharmaceutical and Biomedical Analysis, Washington, United States.

Fillet, M., Bechet, I., Piette, V., & Crommen, J. (1999). Separation of nonsteroidal anti-inflammatory drugs by capillary electrophoresis using nonaqueous electrolytes. Electrophoresis, 20 (9), 1907-15. doi:10.1002/(SICI)1522-2683(19990701)20:9<1907::AID-ELPS1907>3.0.CO;2-L

Fillet, M., Chankvetadze, B., Crommen, J., & Blaschke, G. (1999). Designed combination of chiral selectors for adjustment of enantioseparation selectivity in capillary electrophoresis. Electrophoresis, 20 (13), 2691-7. doi:10.1002/(SICI)1522-2683(19990901)20:13<2691::AID-ELPS2691>3.0.CO;2-S

Fillet, M., Chankvetadze, B., Hubert, P., & Crommen, J. (1999). Selectivity enhancement for enantiomeric separations in capillary electrophoresis using dual cyclodextrin systems [Paper presentation]. 23rd International Symposium on high performance liquid phase separations and related techniques, Grenade, Spain.

Fotsing, L., Boulanger, B., Chiap, P., Fillet, M., Hubert, P., & Crommen, J. (1999). Multivariate optimisation approach for the separation of water-soluble vitamins and related compounds by capillary electrophoresis [Poster presentation]. IIIrd Miniaturisation in Liquid Chromatography versus Capillary Electrophoresis Conference, Gand, Belgium.

Fotsing, L., Boulanger, B., Chiap, P., Fillet, M., Hubert, P., & Crommen, J. (1999). Determination of copper, iron and zinc in pharmaceutical formulations by capillary electrophoresis [Poster presentation]. 23rd International Symposium on high performance liquid phase separations and related techniques, Grenade, Spain.

Fotsing, L., Fillet, M., Chiap, P., Hubert, P., & Crommen, J. (1999). Study of adsorption effects in the analysis of pharmaceutical formulations by CE. Journal de Pharmacie de Belgique, 54.

Fotsing, L., Fillet, M., Chiap, P., Hubert, P., & Crommen, J. (1999). Studies on the variability of migration times observed in the analysis of pharmaceutical formulations by capillary electrophoresis [Paper presentation]. 8e Forum des Sciences Pharmaceutiques, Spa, Belgium.

Fotsing, L., Fillet, M., Chiap, P., Hubert, P., & Crommen, J. (1999). Elimination of adsorption effects in the analysis of water-soluble vitamins in pharmaceutical formulations by capillary electrophoresis. Journal of Chromatography. A, 853 (1-2), 391-401. doi:10.1016/S0021-9673(99)00524-5

Fotsing, L., Fillet, M., Chiap, P., Hubert, P., & Crommen, J. (1999). Elimination of adsorption effects in the analysis of pharmaceutical formulations by capillary electrophoresis [Poster presentation]. XIIth International Symposium on High Performance Capillary Electrophoresis, Palm Springs, United States.

Khelili, S., De Tullio, P., Lebrun, P., Fillet, M., Antoine, M.-H., Ouedraogo, R., Dupont, L., Fontaine, J., Felekidis, A., Leclerc, G., Delarge, J., & Pirotte, B. (1999). Preparation and pharmacological evaluation of the R- and S-enantiomers of 3-(2’-butylamino)-4H- and 3-(3’-methyl-2’-butylamino)-4H-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxide, two tissue selective ATP-sensitive potassium channel openers. Bioorganic and Medicinal Chemistry, 7 (8), 1513-1520. doi:10.1016/S0968-0896(99)00082-6

Piette, V., Fillet, M., Hubert, P., & Crommen, J. (1999). Enantiomeric separation of N-derivatised amino acids by non-aqueous capillary electrophoresis using cinchona alkaloids and derivatives as chiral selectors [Poster presentation]. 23rd International Symposium on high performance liquid phase separations and related techniques, Grenade, Spain.

Piette, V., Fillet, M., Hubert, P., & Crommen, J. (1999). Enantiomeric separation of amino acid derivatives by non-aqueous capillary electrophoresis using quinine and related compounds as chiral additives [Poster presentation]. IIIrd Miniaturisation in Liquid Chromatography versus Capillary Electrophoresis Conference, Gent, Belgium.

Fillet, M., Hubert, P., & Crommen, J. (November 1998). Method Development Strategies for the Enantioseparation of Drugs by Capillary Electrophoresis Using Cyclodextrins as Chiral Additives. Electrophoresis, 19 (16-17), 2834-40. doi:10.1002/elps.1150191608

De Tullio, P., Khelili, S., Fillet, M., Ouedraogo, R., Dupont, L., Antoine, M. H., Lebrun, P., Fontaine, J., Delarge, J., & Pirotte, B. (May 1998). Résolutions énantiomériques et évaluations biologiques des isomères du BPDZ 42 et du BPDZ 44 [Poster presentation]. Douzièmes Journées Franco-Belges de Pharmacochimie, Caen, France.

Crommen, J., Ceccato, A., Fillet, M., Chiap, P., Toussaint, B., & Hubert, P. (1998). Method development and validation for the individual quantitation of drug en-antiomers using liquid chromatography or capillary electrophoresis [Paper presentation]. 3rd course on chiral chemistry, Project Tempus S-JEP-09101-95 « New Curriculum in Chiral Chemistry ».

Fillet, M., Fotsing, L., Bonnard, J., & Crommen, J. (1998). Stereoselective determination of S-naproxen in tablets by capillary electrophoresis. Journal of Pharmaceutical and Biomedical Analysis, 18 (4-5), 799-805. doi:10.1016/S0731-7085(98)00218-0