Publications and communications of Philippe Hubert

Horne, J., Beckers, P., Kemik, K., De Bleye, C., Hubert, P., Ziemons, E., & Hubert, C. (31 January 2024). METALLIC NANOPARTICLES CHARACTERIZATION BY INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY [Poster presentation]. CIRMday 2024, Liege, Belgium.

Zhang, Y., Houari, S., Van Laethem, T., Dispas, A., Hubert, P., & Hubert, C. (31 January 2024). Development and validation of an LC-MS/MS method for screening and quantification of trace N-nitrosamines in a pharmaceutical formulation [Paper presentation]. CIRM-day.

Jambo, H., Dispas, A., Pérez-Mayán, L., Rodríguez, I., Ziemons, E., & Hubert, P. (2024). Comprehensive analysis of vitamin D3 impurities in oily drug products using supercritical fluid chromatography–mass spectrometry. Drug Testing and Analysis. doi:10.1002/dta.3670

Hubert, P., Thewissen, D., & Vandeleene, C. (15 June 2023). Formation tout au long de vie et Qualité [Paper presentation]. Se former tout au long de la vie, perspectives, enjeux, défis sous le patronage de l'UNESCO, Liège, Belgium.

Burniat, A., Noël, A., Colige, A., Vanderplasschen, A., de Kerchove d'Exaerde, A., Kupper Cardozo, A., Van Keymeulen, A., Moens, A., Bondue, A., Herpain, A., Marchant, A., Loumaye, A., Beck, B., Van den Heyden, B., Corvilain, B., Lakaye, B., Rogister, B., Malgrange, B., Michiels, C., ... Brunko, E. (2023). Cent scientifiques répliquent à SEA (Suppression des Expériences sur l’Animal vivant) et dénoncent sa désinformation. La Libre Belgique.

Widart, J., Beauvois, V., Lambert, V., Maesen, P., & Hubert, P. (2023). Rapport d'activités RQLab - Année 2022.

Zhang, Y., Van Laethem, T., Ziémons, T., Dispas, A., Hubert, P., & Hubert, C. (28 March 2023). Développement assisté in silico d’une méthode LC-MS/MS pour la détermination de 17 nitrosamines dans une matrice médicamenteuse [Paper presentation]. 15ème Congrès de l'Association Francophone des Sciences Séparatives (SEP23), Paris, France.

Kumari, P., Van Laethem, T., Hubert, P., Fillet, M., Sacre, P.-Y., & Hubert, C. (10 February 2023). Quantitative Structure Retention-Relationship Modeling: Towards an Innovative General-Purpose Strategy. Molecules, 28 (4), 1696. doi:10.3390/molecules28041696

Zhang, Y., Ziémons, T., Van Laethem, T., Dispas, A., Hubert, P., & Hubert, C. (01 February 2023). In-silico-assisted development of LC-MS/MS methods for the determination of 17 N-nitrosamines in a drug matrix [Paper presentation]. CIRM-day.

Van Laethem, T., Kumari, P., Boulanger, B., Hubert, P., Fillet, M., Sacre, P.-Y., & Hubert, C. (28 November 2022). User-Driven Strategy for In Silico Screening of Reversed-Phase Liquid Chromatography Conditions for Known Pharmaceutical-Related Small Molecules. Molecules, 27 (23), 8306. doi:10.3390/molecules27238306

Zhang, Y., Hubert, P., & Hubert, C. (2022). Investigation of potential substandard dry powder inhalers on EU and North African markets – Evaluation of the delivered and fine particle doses. Journal of Drug Assessment, 1-19. doi:10.1080/21556660.2022.2125727

Elderderi, S., Sacre, P.-Y., Wils, L., Chourpa, I., Elbashir, A. A., Hubert, P., Byrne, H. J., Boudesocque-Delaye, L., Ziemons, E., & Bonnier, F. (27 July 2022). Comparison of Vibrational Spectroscopic Techniques for Quantification of Water in Natural Deep Eutectic Solvents. Molecules, 27 (15), 4819. doi:10.3390/molecules27154819

Hamla, S., Sacre, P.-Y., Derenne, A., Cowper, B., Goormaghtigh, E., Hubert, P., & Ziemons, E. (09 July 2022). A New Alternative Tool to Analyse Glycosylation in Monoclonal Antibodies Based on Drop-Coating Deposition Raman imaging: A Proof of Concept. Molecules, 27 (14), 4405. doi:10.3390/molecules27144405

Van Laethem, T., Kumari, P., Hubert, P., Fillet, M., Sacre, P.-Y., & Hubert, C. (June 2022). A pharmaceutical-related molecules dataset for reversed-phase chromatography retention time prediction built on combining pH and gradient time conditions. Data in Brief, 42, 108017. doi:10.1016/j.dib.2022.108017

Widart, J., Beauvois, V., LAMBERT, V., Maesen, P., & Hubert, P. (2022). Rapport d'activités RQLab - Année 2021. autre.

Kagheni Mbayahi, E., Kitasuvirwa, W., Ciza Hamuli, P., Waffo Tchounga, C. A., Hubert, P., Sacre, P.-Y., Ziemons, E., Kalonji, N. J.-B., & Marini Djang'Eing'A, R. (02 February 2022). Quality control of anti-infective medicines : case of ciprofloxacin and metronidazole formulations in Butembo [Poster presentation]. CIRM Day 2022, Liège, Belgium.

Sacre, P.-Y., De Bleye, C., Hubert, P., Marini Djang'Eing'A, R., & Ziemons, E. (2022). Interest of Raman spectroscopy for the detection and analysis of poor-quality medicines [Paper presentation]. 9th International Conference on Advanced Applied Raman Spectroscopy (RamanFest2022), Paris, France.

Sacre, P.-Y., Waffo Tchounga, C. A., Ciza Hamuli, P., Avohou, T. H., De Bleye, C., Hubert, P., Marini Djang'Eing'A, R., & Ziemons, E. (2022). Applications of vibrational spectroscopy and hyperspectral imaging for the analysis of substandard and falsified medicines [Paper presentation]. 12th International Symposium on Drug Analysis and the 32nd International Symposium on Pharmaceutical and Biomedical Analysis, Mons, Belgium.

Dispas, A., Hubert, C., & Hubert, P. (December 2021). Perspective: What constitutes a quality paper in drug analysis? Talanta Open, 4, 100054. doi:10.1016/j.talo.2021.100054

Borive Amani, M.* , Marini Djang'Eing'A, R., Kindenge, J. M. (Other coll.), Baruti, E. T. (Other coll.), Bakiantima, E. N. (Other coll.), Agasa, S. B. (Other coll.), & Hubert, P. (Other coll.). (August 2021). Quality Control of Tramadol in Kisangani: Development, Validation, and Application of a UV-Vis Spectroscopic Method. American Journal of Analytical Chemistry, 12 (08), 295-309. doi:10.4236/ajac.2021.128018

Deidda, R.* , Coppey, F.* , Damergi, D., Schelling, C., Coic, L., Veuthey, J.-L., Sacre, P.-Y., De Bleye, C., Hubert, P., Esseiva, P., & Ziemons, E. (2021). New perspective for the in-field analysis of cannabis samples using handheld near-infrared spectroscopy: A case study focusing on the determination of Δ9-tetrahydrocannabinol. Journal of Pharmaceutical and Biomedical Analysis. doi:10.1016/j.jpba.2021.114150

Deidda, R., Schelling, C., Roussel, J.-M., Dispas, A., De Bleye, C., Ziemons, E., Hubert, P., & Veuthey, J.-L. (2020). The analysis of cannabinoids in cannabis samples bysupercritical fluid chromatography and ultra-high-performanceliquid chromatography: A comparison study. Analytical Science Advances, 1-13. doi:10.1002/ansa.202000091

Lecomte, F.* , Aerts, J.* , Plenevaux, A., Defraiteur, C., Chappuis-Hugon, F., Rozet, E., CHIAP, P., Luxen, A., Pichon, V., Hubert, P.* , & Hubert, C.*. (20 February 2020). Performance evaluation of a MIP for the MISPE-LC determination of p-[18F]MPPF and a potential metabolite in human plasma. Journal of Pharmaceutical and Biomedical Analysis, 180. doi:10.1016/j.jpba.2019.113015

Beauvois, V., Widart, J., Hubert, P., Dumont, F., & Janssen, E. (2020). Rapport d'activité RQLab Année 2019.

Ciza Hamuli, P., Sacre, P.-Y., Kanyonyo, M., Waffo Tchounga, C. A., Coic, L., mbinze, J., Ziemons, E., Hubert, P., & Marini Djang'Eing'A, R. (28 January 2020). Application of vibrationnal spectroscopy and chemometrics to access the quality of Locally produced antimalarial medicines in the Democratic Republic of Congo [Poster presentation]. Conférence Chimiométrie 2020, ULiège - Université de Liège, Belgium.

Deidda, R., Damergi, D., Coppey, F., De Bleye, C., Coic, L., Sacre, P.-Y., Hubert, P., Ziemons, E., Esseiva, P., & Veuthey, J.-L. (28 January 2020). Handheld Near Infrared spectroscopy for cannabis analysis: from the analytical problem to the chemometric solution [Paper presentation]. Chimiométrie 2020, Liège, Belgium.

Mavungu Landu, D. J., Frederich, M., Manzambi Kuwekita, J., Bongo-Pasi Nswe, C., Mbinze Kindenge, J., Liégeois, S., Kalenda Tshilombo, N., Mineze Kwete Minga, Ciza Hamuli, P., Hubert, P., & Marini Djang'Eing'A, R. (2020). Quality of antimalarials in Kinshasa peri-urban areas with regard to local pharmaceutical legislation and regulation. International Health, 12 (4), 253–263. doi:10.1093/inthealth/ihz070

Mavungu Landu, D. J., Marini Djang'Eing'A, R., Hubert, P., Frederich, M., Michel, B., Gretry, L., Messina Ndzomo, J. P., Bruyère, O., Reginster, J.-Y., & Manzambi Kuwekita, J. (2020). Les déterminants de l’accès à des médicaments antipaludiques de qualité en territoires périurbains africains : résultats d’une enquête menée à Kinshasa (Congo). Journal d’Épidémiologie et de Santé Publique, 21, 85-100.

De Bleye, C., Cailletaud, J., Dumont, E., Sacré, P.-Y., Gut, Y., Ginot, Y.-M., Hubert, P., & Ziemons, E. (11 October 2019). Application of surface-enhanced Raman chemical imaging (SER-CI) to quantification in pharmaceutical tablets. American Pharmaceutical Review, 22 (6).

Ciza Hamuli, P., Sacre, P.-Y., Waffo Tchounga, C. A., Coic, L., Marini Djang'Eing'A, R., Hubert, P., & Ziemons, E. (14 June 2019). Identification of pharmaceutical products using Handheld NIR and Raman spectrophotometers [Paper presentation]. Journées Internationales de Recherche en Sciences de la Santé 2019, Lubumbashi, Congo - Brazzaville.

Alaoui Mansouri, M., Sacre, P.-Y., Coic, L., De Bleye, C., Dumont, E., Bouklouze, A., Hubert, P., Marini Djang'Eing'A, R., & Ziemons, E. (20 May 2019). COMPARATIVE STUDY OF ACTIVE PHARMACEUTICAL INGREDIENT QUANTITATION THROUGH THE PACKAGING USING HANDHELD SPECTROPHOTOMETERS BASED ON CONVENTIONAL AND SPATIALLY OFFSET RAMAN SCATTERING [Paper presentation]. 20th forum of Pharmaceutical Sciences, Brussels, Belgium.

Deidda, R., Avohou, T. H., Jambo, H., Dispas, A., Orlandini, S., Hubert, P., Ziemons, E., & Hubert, C. (20 May 2019). Principles of Analytical Quality by Design for the development of quality control methods in a pharmaceutical context [Paper presentation]. 20th Forum of Pharmaceutical Sciences - BSPS, Brussels, Belgium.

De Bleye, C., Widart, J., Sacre, P.-Y., Hubert, P., & Ziemons, E. (19 December 2018). Vibra-Santé Hub [Poster presentation]. 1st CIRM Scientific Day, Liège, Belgium.

Deidda, R., Avohou, T. H., Orlandini, S., Baronti, R., Pasquini, B., Furlanetto, S., Hubert, P., & Hubert, C. (19 December 2018). Control strategy applied to a LC-DAD quality control method as part of the analytical quality by design approach: one year of routine use [Paper presentation]. 1st CIRM Scientific Day, Liège, Belgium.

Emonts, P., Dispas, A., Ninane, C. (Other coll.), Hubert, P. (Other coll.), Servais, A.-C. (Other coll.), Ziemons, E. (Other coll.), & Fillet, M. (Other coll.). (19 December 2018). Development and optimization of a derivatization protocol for phenethylamine compounds using FITC-CE-LIF method [Poster presentation]. 1st CIRM Scientific Day, Liège, Belgium.

Castiglione, V., Sacre, P.-Y., Cavalier, E., Hubert, P., GADISSEUR, R., & Ziemons, E. (16 November 2018). Raman chemical imaging, a new tool in kidney stone structure analysis: Case-study and comparison to Fourier Transform Infrared spectroscopy [Poster presentation]. Joint Annual Meeting of the Royal Belgian Society of Laboratory Medicine and the Belgian Thyroid Club.

Clavaud, M., Sacre, P.-Y., Hubert, P., & Ziemons, E. (09 September 2018). Transfer of active pharmaceutical ingredients (API) Raman library from bench top towards handheld spectrometers [Paper presentation]. International Syposium DA-PBA 2018, Leuven, Belgium.

Castiglione, V., Sacre, P.-Y., CAVALIER, E., Hubert, P., GADISSEUR, R., & Ziemons, E. (03 August 2018). Raman Chemical Imaging, a new tool in kidney stone structure analysis: Case-study and comparison to Fourier Transform Infrared spectroscopy. PLoS ONE, 13 (8), 0201460. doi:10.1371/journal.pone.0201460

Nguyen, D., Dortu, F., Dispas, A., Hubert, P., Ziemons, E., & Hernandez, Y. (25 April 2018). Terahertz hyperspectral imaging of lab-prepared versus commercial paracetamol tablets and potential applications [Poster presentation]. SPIE Photonics Europe, Strasbourg, France.

Ciza Hamuli, P., Mbinze Kindenge, J., Sacre, P.-Y., Marini Djang'Eing'A, R., & Hubert, P. (31 January 2018). Développement d’une méthode générique proche infrarouge (PIR) dans le contrôle qualité et la contrefaçon des médicaments [Poster presentation]. 3èmes Journées Médicales, Pharmaceutiques et Odontologiques de Ouagadougou, Ouagadougou, Burkina Faso.

Hubert, P. (30 November 2017). Valider une méthode analytique,… Pourquoi et comment? [Paper presentation]. Chaire Francqui 2017-2018, Bruxelles, Belgium.

Mavungu Landu, D. J., Mikobi Mikobi, C., Beya, R., Pipo Tshiasuma, M., Kayembe, J. M., Gretry, L., Marini Djang'Eing'A, R., Hubert, P., Reginster, J.-Y., Michel, B., Manzambi Kuwekita, J., & Frederich, M. (10 November 2017). Expérience de l’intégration des cours de Médecine traditionnelle dans la Faculté de Médecine de l’Université Notre-Dame du Kasayi à Kananga [Paper presentation]. Médecines en Afrique, entre tradition et modernité, Liège, Belgium.

Hubert, P., Thewissen, D., & Vandeleene, C. (2017). Le référentiel EFQM - La qualité en formation [Paper presentation]. Lancement de la L-KMS, Kinshasa, Congo - Brazzaville.

Habyalimana, V., Mbinze Kindenge, J., Yemoa Loconon, A., Kadima Ntokamunda, J.-L., Hubert, P., & Marini Djang'Eing'A, R. (19 September 2017). Simple LC Isocratic Methods Development, Validation, and Application in the Analysis of Poor Quality Antimalarial Medicines. American Journal of Analytical Chemistry, 8, 582-603. doi:10.4236/ajac.2017.89042

Clavaud, M., Roggo, Y., Allmendinger, A., Martinez, C., Hubert, P., & Ziemons, E. (11 June 2017). Impact of formulation and process parameters on near-infrared spectra: Application for water determination in biopharmaceuticals [Poster presentation]. 18th International Conference on Near Infrared Spectroscopy, Copenhagen, Denmark.

Sacre, P.-Y., Netchacovitch, L., Dumont, E., Cailletaud, J., De Bleye, C., Boiret, M., Hubert, P., & Ziemons, E. (2017). Raman Hyperspectral Imaging: An essential tool in the pharmaceutical field. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/211869.

Clavaud, M., Roggo, Y., Dégardin, K., Lema-Martinez, C., Hubert, P., & Ziemons, E. (2017). Online-Restwasserbestimmung. ChemieXtra: die Fachzeitschrift für die Chemie- und Laborbranche.

Hubert, C., Lebrun, P., Boulanger, B., & Hubert, P. (11 May 2017). Cycle de vie des méthodes, vers une maîtrise intégrée des performances quantitatives [Paper presentation]. AFSEP - Comment garantir un résultat quantitatif ?, Lyon, France.

Marini Djang'Eing'A, R., Ziemons, E., Sacre, P.-Y., & Hubert, P. (2017). Le fléau des faux médicaments [Paper presentation]. Médicaments ou poisons, Liège, Belgium.

Sacre, P.-Y., De Bleye, C., Netchacovitch, L., Hubert, P., & Ziemons, E. (2017). Raman Hyperspectral Imaging: An essential tool in the pharmaceutical field [Paper presentation]. Live Webinar, Paris, France.

Kalenda Tshilombo, N., Ciza Hamuli, P., Mavungu Landu, D. J., Mwamba, P., Waffo Tchounga, C., Tidiane, D., Mbinze, J., Hubert, P., & Marini Djang'Eing'A, R. (March 2017). INVESTIGATION DE LA QUALITE D’ANTIBIOTIQUES A BASE D'AMOXICILLINE DANS LE CADRE DE LA SURVEILLANCE DU MARCHE OFFICIEL ET PERIPHERIQUE DE QUELQUES VILLES DE LA R.D. CONGO [Poster presentation]. 12ème Congrès Francophone sur les sciences séparatives et les couplages de AFSEP, Paris, France.

Habyalimana, V., Mbinze Kindenge, J., Yemoa, L., Waffo Tchounga, C., Diallo, T., Kalenda Tshilombo, N., Kadima Ntokamunda, J.-L., Lebrun, P., Hubert, P., & Marini Djang'Eing'A, R. (18 October 2016). APPLICATION OF DESIGN SPACE OPTIMIZATION STRATEGY TO THE DEVELOPMENT OF LC METHODS FOR SIMULTANEOUS ANALYSIS OF 18 ANTIRETROVIRAL MEDICINES AND 4 MAJOR EXCIPIENTS USED IN VARIOUS PHARMACEUTICAL FORMULATIONS [Paper presentation]. 19th Forum of Pharmaceutical Sciences / BELGIAN SOCIETY OF PHARMACEUTICAL SCIENCES, Brussels, Belgium.

Kalenda Tshilombo, N., Waffo Tchounga, C., Diallo, T., Mbinze Kindenge, J., Dibungi T. Kalenda, P., Hubert, P., & Marini Djang'Eing'A, R. (18 October 2016). QUALITY EVALUATION OF AMOXICILLIN AND COMBINATION OF AMOXICILLIN – POTASSIUM CLAVULANATE AS PART OF INVESTIGATION OF THE OFFICIAL AND PERIPHERAL DRUG MARKET IN KINSHASA, LUMBUBASHI AND KOLWEZI - DRC [Paper presentation]. 19th Forum of Pharmaceutical Sciences, Bruxelles, Belgium.

Sacre, P.-Y., Ziemons, E., Hubert, P., & Marini Djang'Eing'A, R. (Other coll.). (2016). Médicaments usage de faux. Moustique.

Widart, J., Beauvois, V., Dumont, F., LASRI, S., LAMBERT, V., PIRSON, L., & Hubert, P. (2016). Réseau Qualité des Laboratoire de l'ULg - Rapport d'activité Février 2016.

Andri, B., Dispas, A., Marini Djang'Eing'A, R., & Hubert, P. (January 2016). Overview of the Analytical Lifecycle of Supercritical Fluid Chromatography Methods. American Journal of Analytical Chemistry, 7, 75-91. doi:10.4236/ajac.2016.71008

Habyalimana, V., Mbinze Kindenge, J., Kalenda Tshilombo, N., Dispas, A., Yemoa Loconon, A., Sacre, P.-Y., Widart, J., De Tullio, P., Counerotte, S., Kadima Ntokamunda, J.-L., Ziemons, E., Hubert, P., & Marini Djang'Eing'A, R. (02 December 2015). Analytical Tools and Strategic Approach to Detect Poor Quality Medicines, Identify Unknown Components, and Timely Alerts for Appropriate Measures: Case Study of Antimalarial Medicines. American Journal of Analytical Chemistry, 6, 977-994. doi:10.4236/ajac.2015.613093

Mbinze Kidenge, J.* , Sacre, P.-Y.* , Yemoa, A., Mavar Tayey Mbay, J., Habyalimana, V., Kalenda, N., Hubert, P., Marini Djang'Eing'A, R., & Ziemons, E. (10 July 2015). Development, validation and comparison of NIR and Raman methods for the identification and assay of poor-quality oral quinine drops. Journal of Pharmaceutical and Biomedical Analysis, 111, 21-27. doi:10.1016/j.jpba.2015.02.049

Aerts, J., Giacomelli, F., Hubert, P., Ianniello, J., & Marini Djang'Eing'A, R. (09 May 2015). RADIOPHARMACY GMP QC HPLC VALIDATION [Paper presentation]. 17 th symposium the Belgian Society of Nuclear Medicine, Maastricht, Netherlands.

Ziemons, E., Chavez, P.-F., Netchacovitch, L., De Bleye, C., Sacre, P.-Y., & Hubert, P. (29 April 2015). Intérêt de la spectroscopie vibrationnelle dans le cadre de l'analyse pharmaceutique [Paper presentation]. Séminaire de l'école doctorale thématique en Sciences Pharmaceutiques, Bruxelles, Belgium.

Ziemons, E., Sacre, P.-Y., Marini Djang'Eing'A, R., & Hubert, P. (2015). Falsification des médicaments: Est-il possible d'améliorer la puissance des outils de détection ? [Paper presentation]. Liège Créative, Liège, Belgium.

Hubert, C., Houari, S., Rozet, E., Lebrun, P., & Hubert, P. (2015). Towards a full integration of optimization and validation phases: An Analytical-Quality-by-Design approach. Journal of Chromatography. A. doi:10.1016/j.chroma.2015.03.059

Sacre, P.-Y., Netchacovitch, L., De Bleye, C., Chavez, P.-F., Servais, C., Klinkenberg, R., Streel, B., Hubert, P., & Ziemons, E. (2015). Thorough characterization of a Self-Emulsifying Drug Delivery System with Raman hyperspectral imaging: A case study. International Journal of Pharmaceutics, 484, 85-94. doi:10.1016/j.ijpharm.2015.02.052

Netchacovitch, L., De Bleye, C., Chavez, P.-F., Sacre, P.-Y., Hubert, P., & Ziemons, E. (November 2014). Raman hyperspectral imaging: a single tool to characterise pharmaceutical products. European Pharmaceutical Review, 19 (5), 8-11.

Dispas, A., Lebrun, P., & Hubert, P. (June 2014). Quantitative performances of UHPSFC and UHPLC : a comparative study [Paper presentation]. Drug Analysis 2014, Liège, Belgium.

Habyalimana, V., Kalenda Tshilombo, N., Dispas, A., Andri, B., Loconon Yemoa, A., Kindenge Mbinze, J., Kadima Ntokamunda, J., Lebrun, P., Hubert, P., & Marini Djang'Eing'A, R. (June 2014). MULTI-TRANSFER OF GENERIC ANALYTICAL METHODS TO COMBAT POOR QUALITY ANTIMALARIAL MEDICINES: A LABORATORY BASED APPROACH TO SUPPORT DRUG QA/QC SYSTEMS [Poster presentation]. DRUG ANALYSIS 2014: 10th International Symposium on Drug Analysis & 25th International Symposium on Pharmaceutical and Biomedical Analysis.

Sacre, P.-Y., Lebrun, P., Chavez, P.-F., De Bleye, C., Netchacovitch, L., Rozet, E., Klinkenberg, R., Streel, B., Hubert, P., & Ziemons, E. (2014). A new criterion to assess distributional homogeneity in hyperspectral images of solid pharmaceutical dosage forms. Analytica Chimica Acta, 818, 7-14. doi:10.1016/j.aca.2014.02.014

Dispas, A., Lebrun, P., & Hubert, P. (October 2013). Robust SFC method optimization using design space strategy [Paper presentation]. 17e Forum des Sciences Pharmaceutiques, Spa, Belgium.

DUBOIS, N., HALLET, C., SEIDEL, L., Rozet, E., LUPPENS, D., ANSSEAU, M., Hubert, P., Albert, A., & Charlier, C. (October 2013). Estimation du délai entre la consommation d'héroïne et le prélèvement chez des consommateurs chroniques [Poster presentation]. 5èmes Journées Internationales de Toxicologie, Liège, Belgium.

Dispas, A., Mbinze Kindenge, J., Lebrun, P., Kalenda, N., Habyalimana, V., Rozet, E., Marini Djang'Eing'A, R., & Hubert, P. (July 2013). ANALYTICAL DESIGN SPACE STRATEGY FOR THE DEVELOPMENT OF LC METHODS TO COMBAT POTENTIALLY COUNTERFEIT ANTIBIOTIC DRUGS [Paper presentation]. 24th International Symposium on Pharmaceutical and Biomedical Analysis, Bologne, Italy.

Lamalle, C., Sacre, P.-Y., Marini Djang'Eing'A, R., Servais, A.-C., Hubert, P., Fillet, M., & Crommen, J. (June 2013). ANALYTICAL STRATEGIES FOR THE DETECTION AND CHARACTERIZATION OF COUNTERFEIT MEDICINES [Paper presentation]. 24th Symposium on Pharmaceutical and Biomedical Analysis (PBA2013) / RDPA 2013, Bologna, Italy.

Dias, A., Rozet, E., Chataigné, G., Margalho, L., Larondelle, Y., Hubert, P., Roger, H., & Quetin-Leclercq, J. (May 2013). NON-ANTHOCYANIN POLYPHENOLS QUANTIFICATION IN EUTERPE OLERACEA FRUITS BY A UHPLC−LTQ-ORBITRAP MS METHOD [Poster presentation]. Journées internationales AFERP & STOLON.

Chavez, P.-F., De Bleye, C., Sacre, P.-Y., Rozet, E., Hubert, P., & Ziemons, E. (February 2013). Validation methodologies of near infrared spectroscopy methods in pharmaceutical applications. European Pharmaceutical Review, 18 (1), 3-6.

DUBOIS, N., Demaret, I., ANSSEAU, M., Rozet, E., Hubert, P., & Charlier, C. (2013). Plasma level monitoring of the major metabolites of diacetylmorphine (heroin) by the "chasing the dragon" route in severe heroin addicts. Acta Clinica Belgica, 68 (5), 359-367. doi:10.2143/ACB.3323

Lebrun, P., Boulanger, B., Debrus, B., Lambert, P., & Hubert, P. (2013). A Bayesian Design Space for analytical methods based on multivariate models and predictions. Journal of Biopharmaceutical Statistics, 23, 1330–1351. doi:10.1080/10543406.2013.834922

Krier, F., mantanus, J., Ziemons, E., Hubert, P., & Evrard, B. (16 October 2012). Comparison of in-line active content determination of polymeric implant by near infrared spectroscopy and Raman spectroscopy [Poster presentation]. Congrés annuel de l'AAPS2012.

Dispas, A., Lebrun, P., Sassiat, P., Thiébaut, D., Vial, J., & Hubert, P. (October 2012). Innovative green supercritical fluid chromatography development for the separation of neurotransmitters using design space strategy [Paper presentation]. SFC2012, Bruxelles, Belgium.

Mbinze Kindenge, J., Lebrun, P., Debrus, B., Dispas, A., Hubert, C., Rozet, E., Marini Djang'Eing'A, R., & Hubert, P. (June 2012). APPLICATION OF AN INNOVATIVE DESIGN SPACE OPTIMIZATION STRATEGY TO THE DEVELOPMENT OF LC METHODS TO COMBAT POTENTIALLY COUNTERFEIT NSAIDS [Poster presentation]. HPLC 2012, Anaheim, California, United States.

Ziemons, E., De Bleye, C., Chavez, P.-F., Rozet, E., Lebrun, P., & Hubert, P. (10 May 2012). Development of near infrared spectroscopic methods using desirability indexes: How to select the most appropriate calibration model [Paper presentation]. EuPAT 5 - Fith pan-European QbD & PAT Science Conference, Ghent, Belgium.

Mbinze Kindenge, J., Lebrun, P., Debrus, B., Dispas, A., Hubert, P., & Marini Djang'Eing'A, R. (May 2012). THE DEVELOPMENT OF LC GENERIC ANALYTICAL METHODS TO FIGHT COUNTERFEIT NSAIDS USING DESIGN SPACE OPTIMISATION STRATEGY [Paper presentation]. 16ème FORUM DES SCIENCES PHARMACEUTIQUES, Blankenberge, Belgium.

Renard, J.-F., Lecomte, F., Arslan, D., Hubert, P., & Pirotte, B. (May 2012). Evaluation de l'impact au niveau pharmacocinétique de modulations structurales de N-(pyrid-4-yl)alcanesulfonamides [Poster presentation]. 26èmes Journées franco-belges de pharmacochimie, Orléans, France.

Ziemons, E., Mantanus, J., Rozet, E., Lebrun, P., Klinkerberg, R., Streel, B., Evrard, B., & Hubert, P. (March 2012). AN INNOVATIVE APPROACH TO SELECT THE PREDICTION MODEL IN THE DEVELOPMENT OF NIR SPECTROSCOPIC METHODS [Poster presentation]. AGROSTAT 2012, Paris, France.

Rozet, E., Bouabidi, A., Talbi, M., Bouklouze, A., Bourichi, H., El Karbane, M., Boulanger, B., & Hubert, P. (February 2012). ARE CAPABILITY INDICES USEFULL TO ASSESS ANALYTICAL METHODS VALIDITY ? [Poster presentation]. 12th International Symposium on Hyphenated Techniques for Chromatography (HTC-12), Bruges, Belgium.

Rozet, E., Boulanger, B., & Hubert, P. (February 2012). QUALITY BY DESIGN COMPLIANT METHOD VALIDATION [Poster presentation]. 12th International Symposium on Hyphenated Techniques for Chromatography (HTC-12), Bruges, Belgium.

Rozet, E., Debrus, B., Lebrun, P., Boulanger, B., & Hubert, P. (February 2012). COMBINATION OF INDEPENDENT COMPONENT ANALYSIS, DESIGN OF EXPERIMENTS AND DESIGN SPACE FOR A NOVEL METHODOLOGY TO DEVELOP CHROMATOGRAPHIC METHODS [Poster presentation]. 12th International Symposium on Hyphenated Techniques for Chromatography (HTC-12), Bruges, Belgium.

Rozet, E., & Hubert, P. (10 January 2012). Validation of Analytical Methods.

Dias, A. L. S., Rozet, E., Chataigne, G., Oliveira, A. C., Silva, C. A. R., Hubert, P., Roger, H., & Quetin-Leclercq, J. (2012). A RAPID VALIDATED UHPLC-PDA METHOD FOR ANTHOCYANINS QUANTIFICATION FROM EUTERPE OLERACEA FRUITS [Poster presentation]. The International Congress on Natural Products Research, New York City, United States.

Dispas, A., Lebrun, P., Mbinze Kindenge, J., Debrus, B., Mavar Tayer Mbay, J., Boulanger, B., Marini Djang'Eing'A, R., & Hubert, P. (December 2011). Application d'une nouvelle méthode de développement de méthodes chromatographiques pour lutter contre la contrefaçon des médicaments anti-inflammatoires [Paper presentation]. Chimiométrie 2011, Marseille, France.

Boulanger, B., Lebrun, P., Rozet, E., & Hubert, P. (29 November 2011). Design Space ou Espace de Conception [Paper presentation]. Liège Creative, Liege, Belgium.

Mantanus, J., Rozet, E., Van Butsele, K., De Bleye, C., Ceccato, A., Evrard, B., Hubert, P., & Ziemons, E. (October 2011). Silicone-based drug reservoirs manufacturing process - Critical quality attributes evaluation using NIR and Raman spectroscopy [Poster presentation]. AAPS Annual Meeting and Exposition, Washington, United States.

Rozet, E., Debrus, B., Lebrun, P., Boulanger, B., & Hubert, P. (08 September 2011). New Methodology for the Development of Chromatographic Methods [Paper presentation]. 17th International Symposium on Separation Sciences – ISSS 2011, Cluj, Romania.

Rozet, E., & Hubert, P. (08 September 2011). NEW TRENDS IN VALIDATION OF ANALYTICAL METHODS [Paper presentation]. 18th International Symposium on Electro- and Liquid Phase-separation Techniques – ITP 2011, Tbilisi, Georgia.

De Bleye, C., Mantanus, J., Rozet, E., Van Butsele, K., Marini Djang'Eing'A, R., Ceccato, A., Evrard, B., Hubert, P., & Ziemons, E. (September 2011). BUILDING THE QUALITY INTO THE POLYMERIC SOLID DOSAGE FORM MANUFACTURING LINE - CRITICAL QUALITY ATTRIBUTES EVALUATION WITH NIR AND RAMAN PAT TOOLS [Poster presentation]. Recent Development in Pharmaceutical Analysis (RDPA), Pavia, Italy.

Marini Djang'Eing'A, R., Mbinze Kindenge, J., Debrus, B., Lebrun, P., Mantanus, J., Ziemons, E., Lamalle, C., Fillet, M., Rudaz, S., & Hubert, P. (September 2011). IMPLEMENTATION OF GENERIC ANALYTICAL METHODS TO FIGHT AGAINST COUNTERFEIT MEDICINES [Paper presentation]. Recent Development in Pharmaceutical Analysis (RDPA), Pavia, Italy.

Rozet, E., Marini Djang'Eing'A, R., Lebrun, P., Ziemons, E., Boulanger, B., & Hubert, P. (September 2011). A BAYESIAN PREDICTIVE PROBABILITY CRITERION TO ASSESS ANALYTICAL METHODS VALIDITY [Poster presentation]. Recent Development in Pharmaceutical Analysis (RDPA), Pavia, Italy.

Renard, J.-F., Lecomte, F., de Leval, X., Hubert, P., & Pirotte, B. (May 2011). Conception, synthèse et évaluation pharmacologique de N-(pyridin-4-yl)alcanesulfonamides en tant qu'inhibiteurs de cyclooxygénases [Poster presentation]. XVèmes Journées Franco-belges de pharmacochimie, Liège, Belgium.

Rozet, E., & Hubert, P. (04 April 2011). Comment adéquatement déclarer valide ou non valide une méthode analytique ? [Paper presentation]. Journées "Mesures, Normes et Statistique", Montpellier, France.

Marini Djang'Eing'A, R., Ziemons, E., & Hubert, P. (2011). Contrôle qualité. 15e Jour du Mois.

Renard, J.-F., Lecomte, F., de Leval, X., Hubert, P., & Pirotte, B. (January 2011). Pyridine Derivatives of Nimesulide as New Promising Anti-inflammatory Agents [Poster presentation]. Giga Days, Liège, Belgium.

Ziemons, E., Mantanus, J., Rozet, E., Lebrun, P., Klinkenberg, R., Streel, B., Moonen, F., Evrard, B., & Hubert, P. (08 December 2010). Vibrational spectroscopy in pharmaceutical industry: From development of the most appropriate predictive model to routine implementation [Poster presentation]. BioWin Day 2010, Louvain-la-Neuve, Belgium.

Rozet, E., Lebrun, P., Boulanger, B., Ziemons, E., & Hubert, P. (02 December 2010). Evaluating analytical results reliability using a Bayesian probability criterion [Poster presentation]. Congrès Chimimétrie 2010, Paris, France.

Ziemons, E., Mantanus, J., Rozet, E., Lebrun, P., Klinkenberg, R., Streel, B., Evrard, B., Moonen, F., & Hubert, P. (02 December 2010). Use of tolerance intervals in the development of near infrared spectroscopic methods: An innovative way to select the most appropriate calibration model [Poster presentation]. Chimiométrie 2010, Paris, France.

Lebrun, P., Lambert, P., Debrus, B., Hubert, P., Marini Djang'Eing'A, R., Moonen, F., & Boulanger, B. (December 2010). Developing and optimizing analytical chromatographic method in a Quality by Design environment. Bayesian multi-criteria risk-based Design Space to guarantee future quality [Poster presentation]. Chimiométrie 2010, Paris, France.

Krier, F., Brion, M., Debrus, B., Lebrun, P., Driesen, A., Ziemons, E., Evrard, B., & Hubert, P. (15 November 2010). Optimisation and validation of a fast HPLC method for the quantification of sulindac and its related impurities [Poster presentation]. The FIP Pharmaceutical Sciences World Congress 2010 in association with the AAPS Annual Meeting & Exposition, new orléans, United States.

Mantanus, J., Ziemons, E., Streel, B., Klinkenberg, R., Evrard, B., Rantanen, J., & Hubert, P. (15 November 2010). NIR monitoring of solid and liquid forms manufacturing – Development and validation of in-line quantitative methods [Poster presentation]. FIP Pharmaceutical Sciences 2010 world congress, New Orleans, United States.

Mantanus, J., Lebrun, P., Rozet, E., Evrard, B., Hubert, P., & Ziemons, E. (14 October 2010). La spectroscopie proche infrarouge et Raman: Nouvelles armes vertes dans le contrôle de la qualité du médicament [Poster presentation]. Journée Scientifique Annuelle de la Société Royale de Chimie: Chimie Verte, Gembloux, Belgium.

Hubert, P., Ziemons, E., Mantanus, J., Lebrun, P., Boulanger, B., & Rozet, E. (October 2010). RISK MANAGMENT IN THE VALIDATION OF ANALYTICAL METHODS [Paper presentation]. CNFR 2010 Congress, Targu-Mures, Romania.

Mantanus, J., Ziemons, E., Van Butsele, K., Evrard, B., Ceccato, A., & Hubert, P. (24 September 2010). NIR AND RAMAN SPECTROSCOPY AS PAT TOOLS FOR THE MANUFACTURING OF SILICONE-BASED DRUG RESERVOIRS [Paper presentation]. Drug Analysis 2010, Anvers, Belgium.

Dubois, N., Debrus, B., Hubert, P., & Charlier, C. (September 2010). Validated quantitative simultaneous determination of cocaine, opiates and amphetamines in serum by UHPLC-MS/MS [Poster presentation]. Drug Analysis 2010, Antwerp, Belgium.

Lecomte, F., Jasselette, C., Hubert, C., Demarche, S., De Bleye, C., Ceccato, A., Rozet, E., & Hubert, P. (September 2010). Validation of a HILIC method for the determination of cidofovir in plasma [Poster presentation]. Drug Analysis 2010 - International Symposium on Drug Analysis, Antwerp, Belgium.

Marini Djang'Eing'A, R., Lambert, V., Denooz, R., Charlier, C., Hubert, C., Hubert, P., & Rozet, E. (September 2010). TOLERANCE INTERVALS AS CONTROL CHART: COMPARISON TO CLASSIC SHEWHART X̅-R CONTROL CHART [Poster presentation]. International Symposium on Drug Analysis 2010, Anvers, Belgium.

Nistor, I., Debrus, B., Lebrun, P., Lecomte, F., Cao, M., Frederich, M., Angenot, L., Boulanger, B., Oprean, R., & Hubert, P. (September 2010). Application of experimental design and design for the separation of compounds extracted from the leaves of Strychnos Usambarensis [Poster presentation]. Drug analysis 2010, Antwerpen, Belgium.

Nistor, I., Lecomte, F., Mbinze Kindenge, J., Debrus, B., Lebrun, P., Marini Djang'Eing'A, R., Oprean, R., & Hubert, P. (September 2010). Transfer of a conventional LC method for the screening of conterfeit antimalarial medicines to UHPLC [Poster presentation]. Drug analysis 2010, Antwerpen, Belgium.

Rafamantanana, M. H., Debrus, B., Raoelison, G. E., Uverg-Ratsimamanga, S., Hubert, P., & Quetin-Leclercq, J. (September 2010). Application of experimental design for the HPLC-UV-MS separation of aporphine alkaloids from leaves of Spirospermum Penduliflorum thouars [Poster presentation]. Drug Analysis 2010, Antwerp, Belgium.

Ziemons, E., Mantanus, J., Rozet, E., Lebrun, P., Klinkenberg, R., Streel, B., Evrard, B., & Hubert, P. (September 2010). An innovative approach to select the prediction model in the development of NIR spectroscopy methods [Poster presentation]. Drug Analysis, Antwerpen, Belgium.

Renard, J.-F., Lecomte, F., de Leval, X., Hubert, P., & Pirotte, B. (21 May 2010). Nouveaux agents anti-inflammatoires en série N-(4-pyridyl)alcanesulfonamide [Paper presentation]. 24èmes JOURNEES FRANCO-BELGES DE PHARMACOCHIMIE, Woluwé-Saint-Lambert, Belgium.

Mantanus, J., Ziemons, E., Evrard, B., Van Butsele, K., Ceccato, A., & Hubert, P. (05 May 2010). NIR Real-time monitoring of a silicone-based drug reservoir crosslinking process [Poster presentation]. 4th Pan European Pat Science conference, Kuopio, Finland.

Mantanus, J., Ziemons, E., Streel, B., Klinkenberg, R., Evrard, B., Rantanen, J., & Hubert, P. (05 May 2010). NIR as a PAT tool for solid and liquid forms manufacturing - Development and validation of in-line quantitative methods [Poster presentation]. 4th Pan European Pat Science conference, Kuopio, Finland.

Hubert, C., Houari, S., Lecomte, F., Houbart, V., De Bleye, C., Fillet, M., Piel, G., Rozet, E., & Hubert, P. (26 January 2010). Développement et validation d'une méthode de dosage de la glucosamine par SPE/LC/MS dans le plamsa canin [Paper presentation]. Forum des jeunes chercheurs du C.I.R.M, Liège, Belgium.

Lecomte, F., Hubert, C., Rozet, E., & Hubert, P. (26 January 2010). Intérêt de la chromatographie en mode HILIC pour le dosage du cidofovir dans des fluides biologiques [Paper presentation]. Forum des jeunes chercheurs du CIRM - 26 janvier 2010 - ULg, Liège, Belgium.

Nistor, I., Debrus, B., Lebrun, P., Lecomte, F., Martine, C., Frederich, M., Angenot, L., Boulanger, B., Oprean, R., & Hubert, P. (26 January 2010). Optimisation de la séparation des alcaloïdes extraits des feuilles de Strychnos usambarensis au moyen du design space [Paper presentation]. Assemblée générale du CIRM et forum des jeunes chercheurs, Liège, Belgium.

Dubois, N., Debrus, B., Hubert, P., & Charlier, C. (2010). Validated quantitative simultaneous determination of cocaine opiates and amphetamines in serum by U-HPLC coupled to tandem mass spectrometry. Acta Clinica Belgica, 65 (1), 75-84. doi:10.1179/acb.2010.113

Michail, K., Rozet, E., Hubert, P., & Wintersteiger, R. (2010). A double-cartridge SPE-HPLC-UV method for monitoring a humanfriendly anticancer in plasma: Ketoglutarate levels in metastatic carcinoma [Poster presentation]. BioVisionAlexandria, Alexandrie, Belgium.

Rozet, E., & Hubert, P. (2010). Transfert des méthodes analytiques. (ULiège - Université de Liège, Formation Continuée Pharmacien d'Industrie).

Ziemons, E., & Hubert, P. (2010). Activités de recherche du laboratoire de Chimie Analytique [Paper presentation]. Forum des Seniors, Liège, Belgium.

Hubert, C., Houari, S., Lecomte, F., Houbart, V., De Bleye, C., Fillet, M., Piel, G., Rozet, E., & Hubert, P. (01 December 2009). Développement et validation d'une méthode de dosage de la glucosamine par SPE/HILIC/MS dans le plamsa de chien [Poster presentation]. 8ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages, Marseille, France.

Lecomte, F., Demarche, S., Evrard, S., Delaunay, S., Hubert, C., Rozet, E., & Hubert, P. (01 December 2009). Intérêt de la chromatographie liquide d'interactions hydrophiles pour l'analyse de composés polaires dans des matrices complexes [Paper presentation]. 8ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages - SEP09, Marseille, France.

Mbinze Kindenge, J., Marini Djang'Eing'A, R., Debrus, B., Lebrun, P., Lecomte, F., Boulanger, B., & Hubert, P. (December 2009). Développement d’une méthode pour la séparation de 19 antipaludéens par HPLC au moyen de la planification expérimentale et du Design Space [Poster presentation]. 7ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages (SEP'09), Marseille, France.

Nistor, I., Debrus, B., Lebrun, P., Lecomte, F., Cao, M., Frederich, M., Angenot, L., Boulanger, B., Oprean, R., & Hubert, P. (December 2009). Application de la planification expérimentale et du design space pour la séparation des composés extraits des feuilles de Strychnos usambarensis [Poster presentation]. 7ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages (SEP'09), Marseille, France.

Mantanus, J., Ziemons, E., Lebrun, P., Rozet, E., Klinkenberg, R., Streel, B., & Hubert, P. (November 2009). Active content determination of non-coated pharmaceutical pellets by near infrared spectroscopy: Method development, validation and reliability evaluation [Poster presentation]. Annual Meeting and Exposition of the American Association of Pharmaceutical Scientists, Los Angeles, United States.

Debrus, B., Broséus, J., Guillarme, D., Hubert, P., Veuthey, J.-L., Esseiva, P., & Rudaz, S. (October 2009). Implementation of new Fast-GC-MS and UHPLC-MS/MS data in a conventional GC-MS database for heroin profiling [Paper presentation]. 4èmes journées internationales de toxicologie hospitalière, Liège, Belgium.

Marini Djang'Eing'A, R., Rozet, E., Hubert, C., Ziemons, E., & Hubert, P. (October 2009). Estimation de l’incertitude à partir de la stratégie de l’erreur totale : Application pour des méthodes internes et des méthodes normatives [Poster presentation]. 4ème journées internationales de Toxicologie, Liège, Belgium.

Mantanus, J., Ziemons, E., Lebrun, P., Rozet, E., Rudaz, S., Klinkenberg, R., Streel, B., & Hubert, P. (September 2009). Validation of a near infrared spectroscopy method for the quantitative determination of an active ingredient in non-coated pharmaceutical pellets [Poster presentation]. 13th International Meeting of Recent Developments in Pharmaceutical Analysis, Milan, Italy.

Mantanus, J., Ziemons, E., Streel, B., Klinkenberg, R., Evrard, B., Hubert, P., & Rantanen, J. (September 2009). Production line real time near infrared (NIR) monitoring [Paper presentation]. 3rd Annual Pharmaceutical Solid State Research Cluster Symposium, Copenhagen, Denmark.

De Backer, B., Debrus, B., Lebrun, P., Dubois, N., Hubert, P., & Charlier, C. (August 2009). Innovative development and validation of an HPLC/DAD method for the qualitative and quantitative determination of major cannabinoïds in cannabis plant material [Poster presentation]. 47ème meeting de l'International Association of Forensic Toxicologists (TIAFT), Genève, Switzerland.

Debrus, B., Broséus, J., Guillarme, D., Hubert, P., Veuthey, J.-L., Esseiva, P., & Rudaz, S. (August 2009). Transfer of heroin profiling method from conventional GC-MS to Fast-GC-MS and UHPLC-MS/MS [Paper presentation]. TIAFT 2009, Genève, Switzerland.

Mantanus, J., Ziemons, E., Streel, B., Klinkenberg, R., Evrard, B., Hubert, P., & Rantanen, J. (August 2009). Quantitative in-line monitoring of pharmaceutical pellets active content using near infrared spectroscopy [Poster presentation]. 3rd Annual Pharmaceutical Solid State Research Cluster Symposium, Copenhagen, Denmark.

Hubert, C., Houari, S., Houbart, V., De Bleye, C., Fillet, M., Rozet, E., & Hubert, P. (June 2009). Development and validation of a sensitive SPE/LC/MS method for the determination of glucosamine in dog plasma [Poster presentation]. 34th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Dresden, Germany.

Mantanus, J., Ziemons, E., Streel, B., Klinkenberg, R., Evrard, B., Hubert, P., & Rantanen, J. (June 2009). Interfacing near infrared (NIR) spectroscopy with production line - Role of sample movement and density [Poster presentation]. Premier European Platform for Advancing Pharmaceutical Sciences, Nice, France.

Nistor, I., Debrus, B., Lebrun, P., Rozet, E., Ceccato, A., Caliaro, G., Oprean, R., Boulanger, B., & Hubert, P. (27 April 2009). Nouvelle méthodologie pour le développement automatisé de méthodes analytiques en chromatographie liquide pour l'analyse de mélanges de composés inconnus [Paper presentation]. Assemblée générale du CIRM et forum des jeunes chercheurs, Liège, Belgium.

Debrus, B., Lebrun, P., Rozet, E., Nistor, I., Ceccato, A., Caliaro, G., Oprean, R., Boulanger, B., & Hubert, P. (2009). Nouvelle méthodologie pour le développement automatisé de méthodes analytiques en chromatographie liquide pour l’analyse de mélanges de composés inconnus. Spectra Analyse, 268, 28-33.

Rozet, E., Boulanger, B., Rudaz, S., Marini Djang'Eing'A, R., Ziemons, E., & Hubert, P. (2009). Universal applicability of Total Error for the validation of bioanalytical methods [Paper presentation]. 4èmes JOURNEES INTERNATIONALES de toxicologie, liege, Belgium.

Rozet, E., Boulanger, B., Rudaz S, Marini Djang'Eing'A, R., Ziemons, E., & Hubert, P. (2009). Total Error for the Valildation of Bioanalytical methods. Annales de Toxicologie Analytique, 21 (S1), 35.

Hubert, P. (2008). Les techniques analytiques vertes au secours de la santé publique. (Le Pharmacien, N° 30, 8 décembre 2008). Bruxelles, Belgium: Roularta Medica.

Zalfen, A., Nizet, D., Jérôme, C., Jérôme, R., frankenne, F., Foidart, J.-M., Maquet, V., Lecomte, F., Hubert, P., & Evrard, B. (November 2008). Controlled release of drugs from multi-component biomaterials. Acta Biomaterialia, 4 (6), 1788-1796. doi:10.1016/j.actbio.2008.05.021

Ziemons, E., Bourichi, H., Mantanus, J., Lebrun, P., Bouklouze, A., Cherrah, Y., & Hubert, P. (October 2008). Analyse quantitative de mélanges binaires de deux formes cristallines du fluconazole par la spectroscopie proche infrarouge et par diffraction des rayons X: comparaison des deux méthodes [Paper presentation]. 2ème Congrès des Sciences Analytiques, Casablanca, Morocco.

Debrus, B., Lebrun, P., Ceccato, A., Caliaro, G., Rozet, E., Rupérez, J., Barbas, C., Boulanger, B., & Hubert, P. (July 2008). Chromatographic separation of a pharmaceutical formulation using Design of Experiment and Design Space [Poster presentation]. 11th conference on Chemometrics in Analytical Chemistry (CAC'2008), Montpellier, France.

Debrus, B., Lebrun, P., Ceccato, A., Caliaro, G., Jupérez, J., Barbas, C., Boulanger, B., & Hubert, P. (June 2008). Usefulness of design space for the optimization of chromatographic separations [Paper presentation]. 19th International Symposium on Pharmaceutical and Biomedical Analysis (PBA 2008), Gdansk, Poland.

Cavalier, E., Rozet, E., Dubois, N., Charlier, C., Hubert, P., Chapelle, J.-P., Krzesinski, J.-M., & Delanaye, P. (2008). Performance of iohexol determination in serum and urine by HPLC: validation, risk and uncertainty assessment. Clinica Chimica Acta, 396, 80-85. doi:10.1016/j.cca.2008.07.011

Mantanus, J., Ziemons, E., Lebrun, P., Rozet, E., Klinkenberg, R., Streel, B., Evrard, B., & Hubert, P. (2008). Determination of moisture content in pharmaceutical pellets using near infrared spectroscopy: Method development and validation [Paper presentation]. PAT Workshop, Gent, Belgium.

Mantanus, J., Ziemons, E., Lebrun, P., Rozet, E., Klinkenberg, R., Streel, B., & Hubert, P. (2008). Moisture content determination of pharmaceutical pellets by near infrared spectroscopy: model selection, evaluation and validation [Poster presentation]. 11th Conference on Chemometrics in Analytical Chemistry, Montpellier, France.

Rozet, E., Dewe, W., Boulanger, B., Ziemons, E., Hubert, C., Moonen, F., & Hubert, P. (2008). Simultaneous improvement of the predictive character of the validation data and estimation of measurement uncertainty [Paper presentation]. Agrostat, Louvain-la-Neuve, Belgium.

Ziemons, E., Mantanus, J., Lebrun, P., Rozet, E., & Hubert, P. (2008). Reflexions, La Chimie Analytique Verte. (Planet'ULg, ULiège - Université de Liège). Reflexions.

Dalmi, M., Hubert, C., Breuer, A., & Hubert, P. (November 2007). Spéciation et dosage de Sn(IV) dans un catalyseur, l'octanoate d'étain (II). Etude de deux paramètres importants du processus analytique [Poster presentation]. JSNES 2007, Mohammedia, Morocco.

Lecomte, F., Aerts, J., Plenevaux, A., Lignon, S., Chapuis-Hugon, F., Chiap, P., Crommen, J., Luxen, A., Pichon, V., & Hubert, P. (September 2007). PPERFORMANCE EVALUATION OF TWO MIPS FOR THE SPE-LC-UV DETERMINATION OF p-[18F]MPPF IN PLASMA [Poster presentation]. RDPA 2007, 12th Internatioinal Meeting on Recent Developments in Pharmaceutical Analysis, Island of Elba, Italy.

Hubert, C., streel, B., Sibenaler, R., Chiap, P., & Hubert, P. (July 2007). Development and pre-validation of a high sensitive method for the determination of levonorgestrel in human plasma by SPE/LC/MS-MS [Poster presentation]. 31th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Gand, Belgium.

Lebrun, P., Debrus, B., Boulanger, B., Caliaro, G., Ceccato, A., & Hubert, P. (June 2007). Numerical separation in HPLC-UV-DAD with Independent Component Analysis (ICA) using high order statistics for the automated identification of peaks [Poster presentation]. HPLC 2007, Gent, Belgium.

Lecomte, F., Aerts, J., Plenevaux, A., Lignon, S., Denjean, C., Chapuis-Hugon, F., Chiap, P., Crommen, J., Luxen, A., Pichon, V., & Hubert, P. (June 2007). DEVELOPMENT AND VALIDATION OF A METHOD FOR THE LC DETERMINATION p-[18F]MPPF IN PLASMA USING A MISPE [Poster presentation]. HPLC 2007 - 31st International Symposium on High Performance Liquid Phase Separations and Related Techniques, Ghent, Belgium.

Marini Djang'Eing'A, R., Servais, A.-C., Rozet, E., Chiap, P., Boulanger, B., Rudaz, S., Crommen, J., Hubert, P., & Fillet, M. (June 2007). Enantiomeric purity testing of S-timolol by non-aqueous CE using heptakis(2,3-di-O-methyl-6-O-Sulfo)-β-cyclodextrin as chiral additive – Validation using the accuracy profile strategy and estimation of uncertainty [Poster presentation]. 31st International Symposium on HPLC and Related techniques, Gand, Belgium.

Debrus, B., Lebrun, P., Boulanger, B., Dewé, W., Ceccato, A., & Hubert, P. (20 March 2007). Séparation numérique et quantification automatique de pics en CLHP-UV grâce à l’utilisation de l’analyse en composantes indépendantes (ICA) [Paper presentation]. SEP 2007, Grenoble, France.

Debrus, B., Lebrun, P., Boulanger, B., Dewé, W., Ceccato, A., & Hubert, P. (20 March 2007). Evaluation d'une nouvelle méthode pour le développement entièrement automatisé de méthodes analytiques en chromatographie liquide [Poster presentation]. SEP 2007, Grenoble, France.

Ziemons, E., Rozet, E., Lejeune, R., Angenot, L., & Hubert, P. (20 March 2007). Dosage en ligne d'une molécule d'origine naturelle dans le CO2 supercritique à l'aide d'une cellule à haute pression équipée de fibres optiques couplant un spectrophotomère IRTF à un extracteur à fluide supercritique [Poster presentation]. SEP 2007, Grenoble, France.

Hubert, C., Rozet, E., Ceccato, A., Dewé, W., Ziemons, E., Moonen, F., Michail, K., Wintersteiger, R., Streel, B., Boulanger, B., & Hubert, P. (March 2007). Validation versus routine : Evaluation de l'aspect prédictif de l'intervalle de tolérance [Poster presentation]. 7ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages, Grenoble, France.

Lecomte, F., Aerts, J., Houbart, V., Plenevaux, A., Lignon, S., Chiap, P., Crommen, J., Luxen, A., Pichon, V., & Hubert, P. (2007). EVALUATION DE DEUX POLYMERES A EMPREINTES MOLECULAIRES POUR LE DOSAGE DU p-[18F]MPPF DANS LE PLASMA [Poster presentation]. 7ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages - SEP07, Grenoble, France.

Martin, G., Chiap, P., Paquet, P., Pierard, G., De Tullio, P., Martin, Y., Rozet, E., Hubert, P., Crommen, J., & Fillet, M. (2007). Development of a mass spectrometry method for the determination of a melanoma biomarker, 5-S-cysteinyldopa, in human plasma using solid phase extraction for sample clean-up. Journal of Chromatography. A, 1156 (1-2), 141-8. doi:10.1016/j.chroma.2006.12.088

Boulanger, B., Dewé, W., Ceccato, A., Debrus, B., Lebrun, P., & Hubert, P. (December 2006). Utilisation de l’Analyse en Composantes Indépendantes (ICA) pour la séparation numérique des pics et la quantification automatique en CLHP-UV [Paper presentation]. Chimiométrie 2006, Paris, France.

Lebrun, P., Boulanger, B., Hubert, P., Debrus, B., & Govaerts, B. (December 2006). Statistical Models and Multi-Criteria Optimization Techniques in Chromatography [Paper presentation]. Chimiométrie 2006, Paris, France.

Marini Djang'Eing'A, R., Chiap, P., Boulanger, B., Rudaz, S., Rozet, E., Crommen, J., & Hubert, P. (November 2006). Comparaison de trois approches pour l'estimation de l'incertitude [Paper presentation]. 3ème journée internationale de toxicologie hospitalière, Liège, Belgium.

Lecomte, F., Aerts, J., Plenevaux, A., Lignon, S., Haber, G., Boulanger, B., Chiap, P., Luxen, A., & Hubert, P. (September 2006). EVALUATION OF MOLECULARLY IMPRINTED POLYMERS BY MEANS OF EXPERIMENTAL DESIGN PRIOR TO THE DETERMINATION OF p-[18F]MPPF IN PLASMA [Poster presentation]. MIP2006 - Fourth International Workshop on Molecularly Imprinted Polymers, Cardiff, United Kingdom.

Hubert, C., Lambert, A., Ziemons, E., Hubert, P., & Lejeune, R. (May 2006). Speciation analysis of Sn(II) and Sn(IV) in stannous octoate using differential pulse polarography [Poster presentation]. Drug Analysis 2006, Namur, Belgium.

Hubert, C., Rozet, E., Boulanger, B., Dewé, W., Breuer, A., Collard, L., Evrard, B., & Hubert, P. (May 2006). Validation of a LC method for the determination of levonorgestrel released from a polymeric matrix. A two days protocol [Poster presentation]. Drug Analysis 2006, Namur, Belgium.

Marini Djang'Eing'A, R., Rozet, E., Ziemons, E., Chiap, P., Boulanger, B., Rudaz, S., Servais, A.-C., Fillet, M., Crommen, J., & Hubert, P. (May 2006). COMPARISON OF THREE DIFFERENT APPROACHES FOR UNCERTAINTY ESTIMATION CONSIDERING LC AND CE METHODS [Paper presentation]. A joint meeting of two distinguished series: the 8th International Symposium on Drug Analysis and the 17th International Symposium on Pharmaceutical and Biomedical Analysis, Namur, Belgium.

Lecomte, F., Boulanger, B., Hall, A. J., Sellergren, B., Crommen, J., Chiap, P., & Hubert, P. (March 2006). Développement d’une méthode de dosage automatisé du méthotrexate dans le plasma humain par couplage direct à la chromatographie liquide de l’extraction sur phase solide à empreintes moléculaires [Poster presentation]. Forum LABO & Forum BIOTECH 2006, Paris, France.

Rozet, E., Boulanger, B., Dewe, W., Chiap, P., Moonen, F., Govaerts, B., Crommen, J., & Hubert, P. (2006). GERER LE RISQUE LORS DE LA VALIDATION DES METHODES ANALYTIQUES : APPLICATION A LA DETERMINATION D’IMPURETES [Paper presentation]. Congrès des Sciences Analytiques, Marrakech, Morocco.

Ziemons, E., Barillaro, V., Rozet, E., Wandij Mbakop, N., Lejeune, R., Angenot, L., Thunus, L., & Hubert, P. (2006). Use of the accuracy profile for the validation of a direct determination of tagitinin C in Tithonia diversifolia leaves by on-line coupling of supercritical CO2 extraction to FT-IR spectroscopy by means of optical fibres [Poster presentation]. Drug Analysis, Namur, Belgium.

Ziemons, E., Lejeune, R., Angenot, L., Thunus, L., & Hubert, P. (2006). Etude en temps réel du processus d'extraction de la tagitinine C en fonction des caractéristiques physico-chimiques du CO2 supercritique à l'aide de fibres optiques couplant un spectrophotomètre IRTF à un extracteur à fluide supercritique [Poster presentation]. Forum Labo & Forum Biotech, Paris, France.

Lecomte, F., Boulanger, B., Hall, A. J., Sellergren, B., Rozet, E., Crommen, J., Chiap, P., & Hubert, P. (September 2005). OPTIMIZATION OF MOLECULARLY IMPRINTED SOLID-PHASE EXTRACTION BY MEANS OF EXPERIMENTAL DESIGN PRIOR TO THE DETERMINATION OF METHOTREXATE IN HUMAN PLASMA [Poster presentation]. RDPA 2005 - 11th International Meeting on Recent Developments in Pharmaceutical Analysis, Rimini, Italy.

Lecomte, F., Hall, A. J., Sellegren, B., Crommen, J., Hubert, P., & Chiap, P. (June 2005). Evaluation of molecularly imprinted polymers for selective extraction of methotrexate from human plasma prior to its LC determination [Poster presentation].   HPLC 2005 - 29th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Stockholm, Sweden.

Servais, A.-C., Fillet, M., Chiap, P., Dewé, W., Hubert, P., & Crommen, J. (11 March 2005). Influence of the nature of the electrolyte on the chiral separation of basic compounds in nonaqueous capillary electrophoresis using heptakis(2,3-di-O-methyl-6-O-sulfo)-beta-cyclodextrin. Journal of Chromatography. A, 1068 (1), 143-150. doi:10.1016/j.chroma.2004.12.010

Chiap, P., Piette, M., Evrard, B., Frankenne, F., Christiaens, B., Piel, G., Cataldo, D., Foidart, J.-M., Delattre, L., Crommen, J., & Hubert, P. (05 March 2005). Automated method for the determination of a new matrix metalloproteinase inhibitor in ovine plasma and serum by coupling of restricted access material for on-line sample clean-up to liquid chromatography. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 817 (1), 109-117. doi:10.1016/j.jchromb.2004.08.042

Rozet, E., Dewé, W., Chiap, P., Lecomte, F., & Hubert, P. (2005). Le transfert d’une méthode de dosage automatisée de 3 catécholamines majeures dans l’urine humaine: utilisation de l’erreur totale comme critère de décision [Paper presentation]. 3èmes Journées Internationales de Toxicologie Hospitalière, Liege, Belgium.

Ziemons, E., Otte, X., Lejeune, R., Rozet, E., Thunus, L., & Hubert, P. (2005). Determination of fenofibrate, ciprofibrate and bezafibrate in mixtures by FTIR spectroscopy [Poster presentation]. 11th meeting on Recent Developments in Pharmaceutical Analysis, Rimini, Italy.

Christians, B., Fillet, M., Chiap, P., Rbeida, O., Ceccato, A., Streel, B., De Graeve, J., Crommen, J., & Hubert, P. (2004). Fully automated method for the liquid chromatographic-tandem mass spectrometric determination of cyproterone acetate in human plasma using restricted access material for on-line sample clean-up. Journal of Chromatography. A, 1056 (1-2), 105-10.

Marini Djang'Eing'A, R., Chiap, P., Hubert, P., & Crommen, J. (25 May 2001). Separation and simultaneous determination of S-timolol maleate, its optical antipode and related substances by liquid chromatography using a cellulose based chiral stationary phase [Paper presentation]. 10th Forum of Pharmaceutical Sciences, Montréal, Canada.

Marini Djang'Eing'A, R., Pantella, A., Chiap, P., Bimazubute, M. A., Hubert, P., & Crommen, J. (April 2000). Development and validation of an LC method for the determination of six corticosteroids, salicylic acid and parabens in different pharmaceutical formulations [Paper presentation]. IXth Forum of Pharmaceutical Sciences, Blankenberge, Belgium.

Fotsing, L., Boulanger, B., Chiap, P., Fillet, M., Hubert, P., & Crommen, J. (2000). Multivariate optimization approach for the separation of water-soluble vitamins and related compounds by capillary electrophoresis. Biomedical Chromatography: BMC, 14 (1), 10-1. doi:10.1002/(SICI)1099-0801(200002)14:1<10::AID-BMC947>3.0.CO;2-8

Bodart, P., Hubert, P., Angenot, L., & Noirfalise, A. (May 1999). Optimization of a high performance thin layer chromatography method to quantify solanines in potatoes [Paper presentation]. 8th Forum of Pharmaceutical Sciences, Spa, Belgium.

Fotsing, L., Fillet, M., Chiap, P., Hubert, P., & Crommen, J. (1999). Elimination of adsorption effects in the analysis of water-soluble vitamins in pharmaceutical formulations by capillary electrophoresis. Journal of Chromatography. A, 853 (1-2), 391-401. doi:10.1016/S0021-9673(99)00524-5

Fillet, M., Hubert, P., & Crommen, J. (1997). Enantioseparation of nonsteroidal anti-inflammatory drugs by capillary electrophoresis using mixtures of anionic and uncharged beta-cyclodextrins as chiral additives. Electrophoresis, 18 (6), 1013-8. doi:10.1002/elps.1150180625

Bechet, I., Hubert, P., Crommen, J., & Fillet, M. (April 1995). Quantitative Analysis of Non-Steroidal Anti-Inflammatory Drugs by Capillary Zone Electrophoresis. Journal of Pharmaceutical and Biomedical Analysis, 13 (4-5), 497-503. doi:10.1016/0731-7085(95)01339-M

Streel, B., Ceccato, A., Chiap, P., Hubert, P., & Crommen, J. (1995). Injection-generated solvent and pH gradients for sample enrichment on injection of large volumes in microclumn liquid chromatography. Biomedical Chromatography: BMC, 9, 254-256.