Publications and communications of Silvia Blacher

Squatrito, M., Vervier, J., Bindels, J., Bernet, L., Blacher, S., Nisolle, M., & Munaut, C. (01 May 2024). Impaired fertility in adenomyosis: a murine model reveals endometrial receptivity and progesterone resistance imbalances. Reproduction, 167 (5). doi:10.1530/REP-24-0019

Gommes, C., Louis, T., Bourgot, I., Blacher, S., Noël, A., & Maquoi, E. (2023). Remodelling of the fibre-aggregate structure of collagen gels by cancer-associated fibroblasts: a time-resolved grey-tone image analysis based on stochastic modelling. Frontiers in Immunology, 13. doi:10.3389/fimmu.2022.988502

Porquet, F., Weidong, L., Jehasse, K., Gazon, H., Kondili, M., Blacher, S., Massotte, L., Di Valentin, E., Furling, D., Gillet, N., Klein, A. F., Seutin, V., & Willems, L. (2023). Specific DMPK-promoter targeting by CRISPRi reverses myotonic dystrophy type 1-associated defects in patient muscle cells. Molecular Therapy: Nucleic Acids, 32, 857 - 871. doi:10.1016/j.omtn.2023.05.007

Squatrito, M., Blacher, S., Henry, L., LABIED, S., Noël, A., Nisolle, M., & Munaut, C. (19 October 2022). Comparison of Morphological and Digital-Assisted Analysis for BCL6 Endometrial Expression in Women with Endometriosis. Journal of Clinical Medicine, 11 (20), 6164. doi:10.3390/jcm11206164

Buntinx, F.* , Lebeau, A.* , Gillot, L., Baudin, L., Ndong Penda, R., Morfoisse, F., LALLEMAND, F., Vottero, G., NIZET, C., Nizet, J.-L., Blacher, S., & Noël, A. (18 October 2022). Single and combined impacts of irradiation and surgery on lymphatic vasculature and fibrosis associated to secondary lymphedema. Frontiers in Pharmacology, 13. doi:10.3389/fphar.2022.1016138

Meçe, O., Houbaert, D., Sassano, M.-L., Durré, T., Maes, H., Schaaf, M., More, S., Ganne, M., García-Caballero, M., Borri, M., Verhoeven, J., Agrawal, M., Jacobs, K., Bergers, G., Blacher, S., Ghesquière, B., Dewerchin, M., Swinnen, J. V., Vinckier, S., ... Agostinis, P. (19 May 2022). Lipid droplet degradation by autophagy connects mitochondria metabolism to Prox1-driven expression of lymphatic genes and lymphangiogenesis. Nature Communications, 13 (1), 2760. doi:10.1038/s41467-022-30490-6

Gillot, L., Lebeau, A., Baudin, L., POTTIER, C., Louis, T., Durré, T., Longuespée, R., Mazzucchelli, G., NIZET, C., BLACHER, S., KRIDELKA, F., & Noël, A. (14 May 2022). Periostin in lymph node pre-metastatic niches governs lymphatic endothelial cell functions and metastatic colonization. Cellular and Molecular Life Sciences, 79 (6), 295. doi:10.1007/s00018-022-04262-w

Dupont, L.* , Noël, A.* , Colige, A.* , Joannes, L. (Other coll.), Morfoisse, F. (Other coll.), BLACHER, S. (Other coll.), Monseur, C. (Other coll.), & Deroanne, C. (Other coll.). (2022). ADAMTS2 and ADAMTS14 substitute ADAMTS3 in adults for proVEGFC activation and lymphatic homeostasis. JCI Insight. doi:10.1172/jci.insight.151509

PAYE, A., Truong, A., Yip, C., Cimino, J., Blacher, S., Munaut, C., Cataldo, D., Foidart, J. M., Maquoi, E., Collignon, J., Delvenne, P., Jerusalem, G., Noël, A., & Sounni, N. E. (15 February 2022). Editor's Note: EGFR Activation and Signaling in Cancer Cells Are Enhanced by the Membrane-Bound Metalloprotease MT4-MMP. Cancer Research, 82 (4), 734. doi:10.1158/0008-5472.CAN-21-4292

LALLEMAND, F., LEROI, N., Blacher, S., Bahri, M. A., Balteau, E., COUCKE, P., Noël, A., Plenevaux, A., & Martinive, P. (2021). Tumor Microenvironment Modifications Recorded With IVIM Perfusion Analysis and DCE-MRI After Neoadjuvant Radiotherapy: A Preclinical Study. Frontiers in Oncology. doi:10.3389/fonc.2021.784437

Neyrinck-Leglantier, D., Lesage, J., Blacher, S., Bonnomet, A., Hunziker, W., Noël, A., Dormoy, V., Nawrocki-Raby, B., Gilles, C.* , & Polette, M.*. (December 2021). ZO-1 Intracellular Localization Organizes Immune Response in Non-Small Cell Lung Cancer. Frontiers in Cell and Developmental Biology, 9, 749364. doi:10.3389/fcell.2021.749364

López-Rodríguez, D., Aylwin, C. F., Delli, V., Sevrin, E., Campanile, M., Martin, M., Franssen, D., Gérard, A., Blacher, S., Tirelli, E., Noël, A., Lomniczi, A., & PARENT, A.-S. (August 2021). Multi- and Transgenerational Outcomes of an Exposure to a Mixture of Endocrine-Disrupting Chemicals (EDCs) on Puberty and Maternal Behavior in the Female Rat. Environmental Health Perspectives, 129 (8), 87003. doi:10.1289/EHP8795

Gallez, A., Blacher, S., Maquoi, E., Konradowski, E., Joiret, M., Primac, I., Gérard, C., Taziaux, M., Houtman, R., Geris, L., Lenfant, F., Marangoni, E., Sounni, N. E., Foidart, J.-M., Noël, A., & Pequeux, C. (2021). Estetrol combined to progestogen for menopause or contraception indication is neutral on breast cancer. Cancers. doi:10.3390/cancers13102486

Luis, G.* , Godfroid, A.* , Nishiumi, S., Cimino, J., Blacher, S., Maquoi, E., Wery, C., Collignon, A., Longuespée, R., MONTERORUIZ, L., Dassoul, I., Maloujahmoum, N., Pottier, C., Mazzucchelli, G., De Pauw, E., Bellahcene, A., Yoshida, M., Noël, A., & Sounni, N. E. (2021). Tumor resistance to ferroptosis driven by Stearoyl-CoA Desaturase-1 (SCD1) in cancer cells and Fatty Acid Biding Protein-4 (FABP4) in tumor microenvironment promote tumor recurrence. Redox Biology, 43, 102006. doi:10.1016/j.redox.2021.102006

Van de Velde, M., Ebroin, M., Durré, T., Joiret, M., Gillot, L., Blacher, S., Geris, L., Kridelka, F., & Noël, A. (2021). Tumor exposed-lymphatic endothelial cells promote primary tumor growth via IL6. Cancer Letters, 497, 154-164. doi:10.1016/j.canlet.2020.10.020

Gallez, A., BLACHER, S., Primac, I., Foidart, J.-M., & Pequeux, C. (04 March 2020). Comparison of Estradiol and Estetrol on Estrogen Receptor alpha signaling [Paper presentation]. ISGE 2020.

Hympanova, L., Rynkevic, R., Mori Da Cunha, M. G. M. C., Diedrich, C. M., BLACHER, S., DE LANDSHEERE, L., Mackova, K., Krofta, L., Roovers, J.-P., & Deprest, J. (2020). The ewe as an animal model of vaginal atrophy and vaginal Er:YAG laser application. Menopause (New York, N.Y.), 28 (2), 198-206. doi:10.1097/GME.0000000000001679

Tack, J., Munaut, C., Blacher, S., Noël, A., Nisolle, M., & CHANTRAINE, F. (2020). Abnormal vascular architecture at the placental-maternal interface in preeclampsia. European Gynecology and Obstetrics, 2 (1), 42-46.

Ancel, J., Birembaut, P., de Wolf, M., Durlach, A., Nawrocki-Raby, B., Dalstein, V., Delepine, G., Blacher, S., Deslée, G., Gilles, C., & Polette, M. (19 September 2019). Programmed death–ligand 1 and vimentin: A tandem marker as prognostic factor in NSCLC. Cancers, 11 (10), 1411. doi:10.3390/cancers11101411

Primac, I., Maquoi, E., Blacher, S., Heljasvaara, R., Van Deun, J., Smeland, H. Y. H., Canale, A., Louis, T., Stuhr, L., Sounni, N. E., Cataldo, D., Pihlajaniemi, T., Pequeux, C., De Wever, O., Gullberg, D., & Noël, A. (09 July 2019). Stromal integrin alpha11 regulates PDGFR-beta signaling and promotes breast cancer progression. Journal of Clinical Investigation, 130. doi:10.1172/JCI125890

Dubois, C., Rocks, N., Blacher, S., Primac, I., Gallez, A., Garcia-Caballero, M., Gérard, C., Brouchet, L., Noël, A., Lenfant, F., Cataldo, D., & Pequeux, C. (2019). Lymph/angiogenesis contributes to sex differences in lung cancer through oestrogen receptor alpha signalling. Endocrine-Related Cancer, 26 (2), 201-216. doi:10.1530/ERC-18-0328

Hympanova, L., Rynkevic, R., Urbankova, I., BLACHER, S., DE LANDSHEERE, L., Mackova, K., Krofta, L., & Deprest, J. (2019). Morphological and Functional Changes in the Vagina following Critical Lifespan Events in the Ewe. Gynecologic and Obstetric Investigation, 84 (4), 360-368. doi:10.1159/000495348

Luis, G., Godfroid, A., Blacher, S., Noël, A., Sounni, N. E., Cimino, J. (Other coll.), Nishiumi, S. (Other coll.), & Yoshida, M. (Other coll.). (01 February 2018). Importance of fatty acid desaturation in tumor growth and oxidative stress response occurring during antiangiogenic treatment [Poster presentation]. Séminaire des chercheurs Télévie.

Gérard, C., Hubeau, C., Carnet, O., Bellefroid, M., Sounni, N. E., Blacher, S., Bendavid, G., Moser, M., Fässler, R., Noël, A., Cataldo, D.* , & Rocks, N.*. (2018). Microenvironment-derived ADAM28 prevents cancer dissemination. Oncotarget, 9 (98), 37185-37199. doi:10.18632/oncotarget.26449

Noël, A., Balsat, C., Garcia Caballero, M., Van De Velde, M., Blacher, S., & Kridelka, F. (08 June 2017). Characterization of the pre-metastatic niche in lymph node, in experimental and clinical settings [Poster presentation]. "LYMPHATIC FORUM 2017« Exploring the lymphatic continuum, Chicago, United States.

BALSAT, C., Signolle, N., Goffin, F., DELBECQUE, K., Plancoulaine, B., Sauthier, P., Samouëlian, V., BELIARD, A., Munaut, C., Foidart, J.-M., BLACHER, S., Noël, A., & Kridelka, F. (01 February 2017). Improved computer-assisted analysis of the global lymphatic network in human cervical tissues. Modern Pathology, 30 (2), 313. doi:10.1038/modpathol.2016.196

Donati, K., Sepult, C., Rocks, N., Blacher, S., Gérard, C., Noël, A., & Cataldo, D. (2017). Neutrophil-Derived Interleukin 16 in Premetastatic Lungs Promotes Breast Tumor Cell Seeding. Cancer Growth and Metastasis, 10, 1179064417738513. doi:10.1177/1179064417738513

Garcia-Caballero, M., Paupert, J., Blacher, S., Van De Velde, M., Quesada, A. R., Medina, M. A., & Noël, A. (2017). Targeting VEGFR-3/-2 signaling pathways with AD0157: a potential strategy against tumor-associated lymphangiogenesis and lymphatic metastases. Journal of Hematology and Oncology, 10 (1), 122. doi:10.1186/s13045-017-0484-1

García Caballero, M., Van De Velde, M., Blacher, S., LAMBERT, V., BALSAT, C., Erpicum, C., Durré, T., Kridelka, F., & Noël, A. (2017). Modeling pre-metastatic lymphvascular niche in the mouse ear sponge assay. Scientific Reports, 7, 41494. doi:10.1038/srep41494

Dubois, C., Blacher, S., García Caballero, M., Rocks, N., Pequeux, C., & Cataldo, D. (08 December 2016). Gender differences in lung tumor development: implication of estrogens [Poster presentation]. Séminaire Télévie, Bruxelles, Belgium.

Dubois, C., Blacher, S., García Caballero, M., Rocks, N., Pequeux, C., & Cataldo, D. (09 September 2016). Gender differences in lung tumor development: implication of estrogens [Poster presentation]. Annual Mini symposium 2016, Bruxelles, Belgium.

Truong, A., Yip, C., PAYE, A., Blacher, S., Munaut, C., Deroanne, C., Noël, A., & Sounni, N. E. (February 2016). Dynamics of Internalization and Recycling of the Pro-Metastatic Membrane Type 4-Matrix Metalloproteinase (MT4-MMP) in Breast Cancer Cells. FEBS Journal, 283 (4), 704-22. doi:10.1111/febs.13625

Bourcy, M., Suarez-Carmona, M., Lambert, J., Francart, M.-E., SCHROEDER, H., Delierneux, C., Skrypek, N., Thompson, E. W., JERUSALEM, G., Berx, G., Thiry, M., Blacher, S., Hollier, B. G., Noël, A., Oury, C., Polette, M., & Gilles, C. (2016). Tissue factor induced by epithelial-mesenchymal transition triggers a pro-coagulant state that drives metastasis of circulating tumor cells. Cancer Research, 76 (14), 4270-4282.

HENRY, L., Fransolet, M., LABIED, S., Blacher, S., MASEREEL, M.-C., Foidart, J.-M., Noël, A., Nisolle, M., & Munaut, C. (2016). Supplementation of transport and freezing media with anti-apoptotic drugs improves ovarian cortex survival. Journal of Ovarian Research. doi:10.1186/s13048-016-0216-0

Munaut, C., TEBACHE, L., Blacher, S., Noël, A., Nisolle, M., & CHANTRAINE, F. (2016). Dysregulated circulating miRNAs in preeclampsia. Biomedical Reports, 5 (6), 686-692. doi:10.3892/br.2016.779

Carnet, O.* , Lecomte, J.* , Masset, A., Primac, I., Durré, T., Maertens, L., Detry, B., Blacher, S., Gilles, C., Péqueux, C., Paupert, J., Foidart, J.-M., Jerusalem, G., Cataldo, D., & Noël, A. (2015). Mesenchymal stem cells shed amphiregulin at the surface of lung carcinoma cells in a juxtacrine manner. Neoplasia, 17 (7), 552-63. doi:10.1016/j.neo.2015.07.002

Fransolet, M., Henry, L., LABIED, S., Masereel, M.-C., Blacher, S., Noël, A., Foidart, J.-M., Nisolle, M., & Munaut, C. (2015). Influence of mouse strain on ovarian tissue recovery after engraftment with angiogenic factor. Journal of Ovarian Research, 8 (1), 14. doi:10.1186/s13048-015-0142-6

Henry, L., LABIED, S., Fransolet, M., Kirschvink, N., Blacher, S., Noël, A., Foidart, J.-M., Nisolle, M., & Munaut, C. (2015). Isoform 165 of vascular endothelial growth factor in collagen matrix improves ovine cryopreserved ovarian tissue revascularisation after xenotransplantation in mice. Reproductive Biology and Endocrinology, 13 (1), 15. doi:10.1186/s12958-015-0015-2

Leroi, N., Sounni, N. E., Van Overmeire, E., Blacher, S., Marée, R., Van Ginderachter, J., Lallemand, F., LENAERTS, E., COUCKE, P., Noël, A.* , & MARTINIVE, P.*. (2015). The timing of surgery after neoadjuvant radiotherapy influences tumor dissemination in a preclinical model. Oncotarget. doi:10.18632/oncotarget.5931

Suarez-Carmona, M., Bourcy, M., LESAGE, J., Leroi, N., Syne, L., Blacher, S., Hubert, P., Erpicum, C., Foidart, J.-M., Delvenne, P., Birembaut, P., Noël, A., Polette, M., & Gilles, C. (2015). Soluble factors regulated by epithelial-mesenchymal transition mediate tumour angiogenesis and myeloid cell recruitment. Journal of Pathology, 236 (4), 491-504. doi:10.1002/path.4546

Paye, A., Truong, A., Yip, C., Cimino, J., Blacher, S., Munaut, C., Cataldo, D., Foidart, J.-M., Maquoi, E., COLLIGNON, J., Delvenne, P., Jerusalem, G., Noël, A.* , & Sounni, N. E.*. (October 2014). EGFR activation and signaling in cancer cells are enhanced by the membrane-bound metalloprotease MT4-MMP. Cancer Research, 74 (23), 6758-70. doi:10.1158/0008-5472.CAN-13-2994

Leroi, N., Blacher, S., Marée, R., Noël, A., COUCKE, P., & MARTINIVE, P. (29 June 2014). Does neoadjuvant radiotherapy and the timing of surgery modify metastatic dissemination? [Paper presentation]. 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany.

Amand, M., Erpicum, C., BAJOU, K., Cerignoli, F., Blacher, S., Martin, M., Dequiedt, F., Drion, P., Singh, P., Zurashvili, T., Vandereyken, M., Musumeci, L., Mustelin, T., Moutschen, M., Gilles, C., Noël, A., & Rahmouni, S. (2014). DUSP3/VHR is a pro-angiogenic atypical dual-specificity phosphatase. Molecular Cancer. doi:10.1186/1476-4598-13-108

Blacher, S., Erpicum, C., Lenoir, B., Paupert, J., Moraes, G., Ormenese, S., Bullinger, E., & Noël, A. (2014). Cell invasion in the spheroid sprouting assay: a spatial organisation analysis adaptable to cell behaviour. PLoS ONE, 9 (5), 97019. doi:10.1371/journal.pone.0097019

Lenoir, B., Wagner, D. R., Blacher, S., Sala-Newby, G. B., Newby, A. C., Noël, A., & Devaux, Y. (2014). Effects of adenosine on lymphangiogenesis. PLoS ONE, 9 (3), 92715. doi:10.1371/journal.pone.0092715

Maertens, L., Erpicum, C., Detry, B., Blacher, S., Lenoir, B., Carnet, O., Pequeux, C., Cataldo, D., Lecomte, J., Paupert, J., & Noël, A. (2014). Bone marrow-derived mesenchymal stem cells drive lymphangiogenesis. PLoS ONE, 9 (9), 106976. doi:10.1371/journal.pone.0106976

CANTINIEAUX, D., QUERTAINMONT, R., Blacher, S., Rossi, L., Wanet, T., Noël, A., BROOK, G., Schoenen, J., & Franzen, R. (2013). Conditioned Medium from Bone marrow-derived Mesenchymal Stem Cells improves recovery after Spinal Cord Injury in rats: an original strategy to avoid cell transplantation. PLoS ONE, 8 (8), 69515. doi:10.1371/journal.pone.0069515

Cimino, J., Calligaris, D., Far, J., Debois, D., Blacher, S., Sounni, N. E., Noël, A., & De Pauw, E. (2013). Towards Lipidomics of Low-Abundant Species for Exploring Tumor Heterogeneity Guided by High-Resolution Mass Spectrometry Imaging. International Journal of Molecular Sciences, 14, 24560-24580. doi:10.3390/ijms141224560

Detry, B., Blacher, S., Erpicum, C., Paupert, J., Maertens, L., Maillard, C., Munaut, C., Sounni, N. E., LAMBERT, V., Foidart, J.-M., Rakic, J.-M., Cataldo, D., & Noël, A. (2013). Sunitinib inhibits inflammatory corneal lymphangiogenesis. Investigative Ophthalmology and Visual Science, 54 (5), 3082-93. doi:10.1167/iovs.12-10856

LAMBERT, V., Lecomte, J., Hansen, S., Blacher, S., Alvarez Gonzalez, M.-L., Struman, I., Sounni, N. E., Rozet, E., De Tullio, P., Foidart, J.-M., Rakic, J.-M., & Noël, A. (2013). Laser-induced choroidal neovascularization model to study age-related macular degeneration in mice. Nature Protocols, 8 (11), 2197-2211. doi:10.1038/nprot.2013.135

Otjacques, E., Binsfeld, M., Rocks, N., Blacher, S., Vanderkerken, K., Noël, A., Beguin, Y., Cataldo, D., & CAERS, J. (2013). Mithramycin Exerts an Anti-Myeloma Effect and Displays Anti-Angiogenic Effects through Up-Regulation of Anti-Angiogenic Factors. PLoS ONE, 8 (5), 62818. doi:10.1371/journal.pone.0062818

Fransolet, M., HENRY, L., Rozet, E., Blacher, S., Masereel, M.-C., Kirschvink, N., Noël, A., Foidart, J.-M., NISOLLE, M., Labied, S., & Munaut, C. (10 December 2012). Use of Sheep Ovarian Tissue as a Model to Restore Fertility in Young Cancerous Women [Poster presentation]. Séminaire des chercheurs Télévie 2013.

Pequeux, C., Raymond-Letron, I., Blacher, S., Boudou, F., Adlanmerini, M., Fouque, M., Rochaix, P., Noël, A., Foidart, J.-M., Krust, A., Chambon, P., Brouchet, L., Arnal, J., & Lenfant, F. (2012). Stromal Estrogen Receptor-α Promotes Tumor Growth by Normalizing an Increased Angiogenesis. Cancer Research, 72 (12), 3010-3019. doi:10.1158/0008-5472.CAN-11-3768

Nguyen, N.-Q.-N., Castermans, K., Berndt, S., Herkenne, S., Tabruyn, S., Blacher, S., Lion, M., Noël, A., Martial, J., & Struman, I. (07 November 2011). The Antiangiogenic 16K Prolactin Impairs Functional Tumor Neovascularization by Inhibiting Vessel Maturation. PLoS ONE, 6 (11), 27318-27318. doi:10.1371/journal.pone.0027318

Balsat, C., Blacher, S., Signolle, N., BELIARD, A., Munaut, C., GOFFIN, F., Noël, A., Foidart, J.-M., & Kridelka, F. (2011). Whole Slide Quantification of Stromal Lymphatic Vessel Distribution and Peritumoral Lymphatic Vessel Density in Early Invasive Cervical Cancer: A Method Description. ISRN Obstetrics and Gynecology, 2011, 354861. doi:10.5402/2011/354861

Labied, S., Blacher, S., Carmeliet, P., Noël, A., Frankenne, F., Foidart, J.-M., & Munaut, C. (2011). Transient reduction of placental angiogenesis in PAI-1 deficient mice. Physiological Genomics, 43 (4), 188-98. doi:10.1152/physiolgenomics.00147.2010

Lecomte, J., Louis, K., Detry, B., Blacher, S., Lambert, V., Bekaert, S., Munaut, C., Paupert, J., Blaise, P., Foidart, J.-M., Rakic, J.-M., Krane, S. M., & Noël, A. (2011). Bone marrow-derived mesenchymal cells and MMP13 contribute to experimental choroidal neovascularization. Cellular and Molecular Life Sciences, 68, 677-686. doi:10.1007/s00018-010-0476-6

Lottaz, D., Maurer, C. A., Noël, A., Blacher, S., Huguenin, M., Nievergelt, A., Niggli, V., Kern, A., Müller, S., Seibold, F., Friess, H., Becker-Pauly, C., Stöcker, W., & Sterchi, E. E. (2011). Enhanced Activity of Meprin-a, a Pro-Migratory and Pro-Angiogenic Protease, in Colorectal Cancer. PLoS ONE, 6 (11), 26450. doi:10.1371/journal.pone.0026450

Bruyere, F.* , Melen-Lamalle, L.* , Blacher, S., Detry, B., Masset, A., Lecomte, J., Lambert, V., Maillard, C., Hoyer-Hansen, G., Lund, L. R., Foidart, J.-M., & Noël, A. (2010). Does plasminogen activator inhibitor-1 drive lymphangiogenesis? PLoS ONE, 5 (3), 9653. doi:10.1371/journal.pone.0009653

El Hour, M., Moncada-Pazos, A., Blacher, S., Masset, A., Cal, S., Berndt, S., Detilleux, J., Host, L., Obaya, A. J., Maillard, C., Foidart, J.-M., Noël, A.* , & Lopez-Otin, C.*. (2010). Higher sensitivity of Adamts12-deficient mice to tumor growth and angiogenesis. Oncogene, 29 (20), 3025-32. doi:10.1038/onc.2010.49

Hemmer, M., Kempen, I., De Tullio, P., Frankenne, F., Lambert, V., Blacher, S., Bueb, J.-L., Foidart, J.-M., Noël, A., Tschirhart, E., & Pirotte, B. (2010). New Biological Investigations on 3-Bromophenyl 6-Acetoxymethyl-2-oxo-2H-1-Benzopyran-3-Carboxylate as Anti-angiogenic Agent. Drug Development Research, 71, 1-10. doi:10.1002/ddr.20364

Henno, A., Blacher, S., Lambert, C., Deroanne, C., Noël, A., Lapière, C., de LA BRASSINNE, M., Nusgens, B., & Colige, A. (2010). Histological and transcriptional study of angiogenesis and lymphangiogenesis in uninvolved skin, acute pinpoint lesions and established psoriasis plaques: an approach of vascular development chronology in psoriasis. Journal of Dermatological Science, 57 (3), 162-169. doi:10.1016/j.jdermsci.2009.12.006

LORQUET, S., Berndt, S., Blacher, S., Gengoux, E., Peulen, O., Maquoi, E., Noël, A., Foidart, J.-M., Munaut, C., & Pequeux, C. (2010). Soluble forms of VEGF receptor-1 and -2 promote vascular maturation via mural cell recruitment. FASEB Journal, 24 (10), 3782-95. doi:10.1096/fj.09-149070

Gommes, C., Bons, A.-J., Blacher, S., Dunsmuir, J., & Tsou, A. (August 2009). Practical Methods for Measuring the Tortuosity of Porous Materials from Binary or Gray-Tone Tomographic Reconstructions. AIChE Journal, 55 (8), 2000-2012. doi:10.1002/aic.11812

Almazan, M. D. C., Léonard, A., López-Garzón, J., Abdullah, J., Marchot, P., & Blacher, S. (2009). 3D characterisation of the structure of activated carbon packed beds using X-ray microtomography. In 3rd International Workshop on Process Tomography (CD Rom).

Berndt, S., Blacher, S., PERRIER d'HAUTERIVE, S., Thiry, M., Tsampalas, M., Cruz, A., Pequeux, C., LORQUET, S., Munaut, C., Noël, A.* , & Foidart, J.-M.*. (2009). Chorionic Gonadotropin Stimulation of Angiogenesis and Pericyte Recruitment. Journal of Clinical Endocrinology and Metabolism, 94 (11), 4567-74. doi:10.1210/jc.2009-0443

Chabottaux, V., Ricaud, S., Host, L., Blacher, S., Paye, A., Thiry, M., Anikitos, G., Pestourie, C., Gombert, K., Bruyere, F., Lewandowsky, D., Tavitian, B., Foidart, J.-M., Duconge, F., & Noël, A. (2009). Membrane-Type 4 Matrix Metalloproteinase (MT4-MMP) induces lung metastasis by alteration of primary breast tumor vascular architecture. Journal of Cellular and Molecular Medicine. doi:10.1111/j.1582-4934.2009.00764.x

Henno, A., Blacher, S., Lambert, C., Colige, A., Seidel, L., Noël, A., Lapière, C., De La Brassinne, M., & Nusgens, B. (2009). Altered expression of angiogenesis and lymphangiogenesis markers in the uninvolved skin of plaque-type psoriasis. British Journal of Dermatology, 160 (3), 581-90. doi:10.1111/j.1365-2133.2008.08889.x

Tondi, G., Blacher, S., Léonard, A., Pizzi, A., Fierro, V., Leban, J. M., & Celzard, A. (2009). X-Ray Microtomography Studies of Tannin-Derived Organic and Carbon Foams. Microscopy and Microanalysis, 15, 384-394. doi:10.1017/S1431927609990444

Kempen, I., Hemmer, M., Counerotte, S., Pochet, L., De Tullio, P., Foidart, J.-M., Blacher, S., Noël, A., Frankenne, F., & Pirotte, B. (December 2008). 6-Substituted 2-Oxo-2h-1-Benzopyran-3-Carboxylic Acid Derivatives in a New Approach of the Treatment of Cancer Cell Invasion and Metastasis. European Journal of Medicinal Chemistry, 43 (12), 2735-50. doi:10.1016/j.ejmech.2008.01.024

Léonard, A., Calberg, C., Kerckhofs, G., Wevers, M., Jérôme, R., Pirard, J.-P., Germain, A., & Blacher, S. (August 2008). Characterization of the porous structure of biodegradable scaffolds obtained with supercritical CO2 as foaming agent. Journal of Porous Materials, 15 (4), 397-403. doi:10.1007/s10934-006-9094-y

Blacher, S., Jost, M., Melen-Lamalle, L., Lund, L. R., Romer, J., Foidart, J.-M., & Noël, A. (March 2008). Quantification of in Vivo Tumor Invasion and Vascularization by Computerized Image Analysis. Microvascular Research, 75 (2), 169-78. doi:10.1016/j.mvr.2007.09.002

Léonard, A., Blacher, S., Nimmol, C., & Devahastin, S. (March 2008). Effect of far-infrared radiation assisted drying on microstructure of banana slices: An illustrative use of X-ray microtomography in microstructural evaluation of a food product. Journal of Food Engineering, 85 (1), 154-162. doi:10.1016/j.jfoodeng.2007.07.017

Bruyere, F., Melen-Lamalle, L., Blacher, S., Roland, G., Thiry, M., Moons, L., Frankenne, F., Carmeliet, P., Alitalo, K., Libert, C., Sleeman, J. P., Foidart, J.-M., & Noël, A. (2008). Modeling Lymphangiogenesis in a three-dimensional culture system. Nature Methods, 5 (5), 431-437. doi:10.1038/nmeth.1205

Gommes, C., Job, N., Pirard, J.-P., Blacher, S., & Goderis, B. (2008). Critical opalescence points to thermodynamic instability:relevance to small-angle X-ray scattering of resorcinol–formaldehyde gel formation at low pH. Journal of Applied Crystallography, 41 (4), 663-668. doi:10.1107/S0021889808014994

Léonard, A., Blacher, S., Crine, M., & Jomaa, W. (2008). Evolution of mechanical properties and final textural properties of resorcinol-formaldehyde xerogels during ambient air drying. Journal of Non-Crystalline Solids, 354 (10-11), 831-838. doi:10.1016/j.jnoncrysol.2007.08.024

Léonard, A., Wullens, H., Blacher, S., Marchot, P., Toye, D., Crine, M., & Lodewyckx, P. (2008). In situ observation of wall effects in activated carbon filters by X-ray microtomography. Separation and Purification Technology, 64 (1), 127-130. doi:10.1016/j.seppur.2008.08.008

Lorquet, S., Berndt, S., Blacher, S., Noël, A., Munaut, C., Foidart, J.-M., & Pequeux, C. (2008). Implication of VEGF receptor soluble forms, sVEGFR-1 and sVEGFR-2, in angiogenesis. Acta Clinica Belgica, 63/1, 48-58.

Lorquet, S., Berndt, S., Blacher, S., Noël, A., Munaut, C., Foidart, J.-M., & Pequeux, C. (2008). Implication of soluble receptors of VEGF, sVEGFR-1 and sVEGFR-2, in angiogenesis. American Journal of Reproductive Immunology, 60/1, 85.

Munaut, C., Lorquet, S., Pequeux, C., Blacher, S., Berndt, S., Frankenne, F., & Foidart, J.-M. (2008). Hypoxia is responsible for soluble vascular endothelial growth factor receptor-1 (VEGFR-1) but not for soluble endoglin induction in villous trophoblast. Human Reproduction, 23 (6), 1407-15. doi:10.1093/humrep/den114

Ravet, S., Munaut, C., Blacher, S., Brichant, G., Labied, S., Beliard, A., Chabbert-Buffet, N., Bouchard, P., Foidart, J.-M., & Pintiaux, A. (2008). Persistence of an intact endometrial matrix and vessels structure in women exposed to VA-2914, a selective progesterone receptor modulator. Journal of Clinical Endocrinology and Metabolism, 93 (11), 4525-31. doi:10.1210/jc.2008-0731

Zilli, D., Blacher, S., Cukierman, A. L., Pirard, J.-P., & Gommes, C. (2008). Formation mechanism of Y-junctions in arrays of multi-walled carbon nanotubes. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 327 (1-3), 140-143. doi:10.1016/j.colsurfa.2008.05.042

Nguyen, N.-Q.-N., Cornet, A., Blacher, S., Tabruyn, S., Foidart, J.-M., Noël, A., Martial, J., & Struman, I. (December 2007). Inhibition of tumor growth and metastasis establishment by adenovirus-mediated gene transfer delivery of the antiangiogenic factor 16K hPRL. Molecular Therapy, 15 (12), 2094-2100. doi:10.1038/sj.mt.6300294

Ravet, S., Labied, S., Blacher, S., Frankenne, F., Munaut, C., Fridman, V., Beliard, A., Foidart, J.-M., & Nisolle, M. (December 2007). Endometrial vessel maturation in women exposed to levonorgestrel-releasing intrauterine system for a short or prolonged period of time. Human Reproduction, 22 (12), 3084-3091. doi:10.1093/humrep/dem238

Léonard, A., Guiot, L. P., Pirard, J.-P., Crine, M., Balligand, M., & Blacher, S. (March 2007). Non-destructive characterization of deer (Cervus Elaphus) antlers by X-ray microtomography coupled with image analysis. Journal of Microscopy, 225 (Pt 3), 258-263. doi:10.1111/j.1365-2818.2007.01740.x

Gommes, C., Job, N., Blacher, S., & Pirard, J.-P. (2007). Compressing some sol-gel materials reduces their stiffness: a textural analysis. Studies in Surface Science and Catalysis, 160, 193-200. doi:10.1016/s0167-2991(07)80026-7

Chabottaux, V., Sounni, N. E., Pennington, C. J., English, W. R., van den Brule, F., Blacher, S., Gilles, C., Munaut, C., Maquoi, E., Lopez-Otin, C., Murphy, G., Edwards, D. R., Foidart, J.-M., & Noël, A. (15 May 2006). Membrane-type 4 matrix metalloproteinase promotes breast cancer growth and metastases. Cancer Research, 66 (10), 5165-5172. doi:10.1158/0008-5472.CAN-05-3012

Jost, M., Folgueras, A. R., Frerart, F., Pendas, A. M., Blacher, S., Houard, X., Berndt, S., Munaut, C., Cataldo, D., Alvarez Gonzalez, M.-L., Melen-Lamalle, L., Foidart, J.-M., Lopez-Otin, C., & Noël, A. (May 2006). Earlier onset of tumoral anglogenesis in matrix metalloproteinase-19-deficient mice. Cancer Research, 66 (10), 5234-5241. doi:10.1158/0008-5472.CAN-05-4315

Jost, M., Maillard, C., Lambert, V., Tjwa, M., Blaise, P., Lecomte, J., Bajou, K., Blacher, S., Motte, P., Humblet, C., Defresne, M.-P., Thiry, M., Frankenne, F., Gothot, A., Carmeliet, P., Rakic, J.-M., Foidart, J.-M., & Noël, A. (2006). Plasminogen activator inhibitor type I (PAI-1) controls bone marrow-dependent and independent vascularization. Acta Clinica Belgica, 61 (2, MAR-APR), 87.

Lodewyckx, P., Blacher, S., & Léonard, A. (January 2006). Use of x-ray microtomography to visualise dynamic adsorption of organic vapour and water vapour on activated carbon. Adsorption, 12 (1), 19-26. doi:10.1007/s10450-006-0135-2

Léonard, A., Job, N., Blacher, S., Pirard, J.-P., Crine, M., & Jomaa, W. (July 2005). Suitability of convective air drying for the production of porous resorcinol-formaldehyde and carbon xerogels. Carbon, 43 (8), 1808-1811. doi:10.1016/j.carbon.2005.02.016

Léonard, A., Blacher, S., Marchot, P., Pirard, J.-P., & Crine, M. (February 2005). Moisture profiles determination during convective drying using x-ray microtomography. Canadian Journal of Chemical Engineering, 83 (1), 127-131. doi:10.1002/cjce.5450830121

Laurent-Matha, V., Maruani-Herrmann, Glondu, M., Prebois, C., Gilles, C., Noël, A., Alvarez Gonzalez, M.-L., Blacher, S., Freiss, G., Vignon, F., & Liaudet-Coopman, E. (2005). Catalytically-inactive human cathepsin D triggers fibroblast invasive growth. Journal of Cell Biology, 168 (3), 489-99. doi:10.1083/jcb.200403078

Li, X. R., Tjwa, M., Moons, L., Fons, P., Noël, A., Ny, A., Zhou, J. M., Lennartsson, J., Li, H., Luttun, A., Ponten, A., Devy, L., Bouche, A., Oh, H., Manderveld, A., Blacher, S., Communi, D., Savi, P., Bono, F., ... Carmeliet, P. (January 2005). Revascularization of ischemic tissues by PDGF-CC via effects on endothelial cells and their progenitors. Journal of Clinical Investigation, 115 (1), 118-127. doi:10.1172/JCI19189

Blacher, S., Léonard, A., Heinrichs, B., Tcherkassova, N., Ferauche, F., Crine, M., Marchot, P., Loukine, E., & Pirard, J.-P. (14 July 2004). Image analysis of X-ray microtomograms of Pd-Ag/SiO2 xerogel catalysts supported on Al2O3 foams. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 241 (1-mars Sp. Iss. SI), 201-206. doi:10.1016/j.colsurfa.2004.04.006

Deumens, R., Koopmans, G. C., Den Bakker, C. G. J., Maquet, V., Blacher, S., Honig, W. M. M., Jérôme, R., Pirard, J.-P., Steinbusch, H. W. M., & Joosten, E. A. J. (2004). Alignment of glial cells stimulates directional neurite growth of cns neurons in vitro. Neuroscience, 125 (3), 591-604. doi:10.1016/j.neuroscience.2004.02.010

Gommes, C., Blacher, S., Dupont-Pavlovsky, N., Bossuot, C., Lamy, M., Brasseur, A., Marguillier, D., Fonseca, A., McRae, E., Nagy, J. B., & Pirard, J.-P. (2004). Comparison of different methods for characterizing multi-walled carbon nanotubes. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 241 (1-3), 155-164. doi:10.1016/j.colsurfa.2004.04.050

Blacher, S., Maquet, V., Luyckx, F., Martin, D., Schoenen, J., Moonen, G., Jérôme, R., & Pirard, J.-P. (March 2003). Image analysis of the axonal ingrowth into poly(D,L-lactide) porous scaffolds in relation to the 3-D porous structure. Biomaterials, 24 (6), 1033-1040. doi:10.1016/S0142-9612(02)00423-4

Gommes, C., Blacher, S., Masenelli-Varlot, K., Bossuot, C., McRae, E., Fonseca, A., Nagy, J. B., & Pirard, J.-P. (2003). Image analysis characterization of multi-walled carbon nanotubes. Carbon, 41 (13), 2561-2572. doi:10.1016/S0008-6223(03)00375-0

Groslambert, S., Blacher, S., & Crine, M. (2003). Hydrodynamique et morphologie d'une bactérie filamenteuse dans un fermenteur à cuve agitée. Tribune de l'Eau, 56 (622), 58-64.

Léonard, A., Blacher, S., Pirard, R., Marchot, P., Pirard, J.-P., & Crine, M. (2003). Multiscale texture characterization of wastewater sludges dried in a convective rig. Drying Technology, 21 (8), 1507-1526. doi:10.1081/DRT-120024490

Masson, V., Devy, L., Grignet, C., Berndt, S., Bajou, K., Blacher, S., Roland, G., Chang, Y., Fong, T., Carmeliet, P., Foidart, J.-M., & Noël, A. (28 October 2002). Mouse Aortic Ring Assay: A New Approach of the Molecular Genetics of Angiogenesis. Biological Procedures Online, 4, 24-31. doi:10.1251/bpo30

Groslambert, S., Blacher, S., & Crine, M. (2002). Modelling of hydrodynamics of a stirred tank fermenter, and of its influence on the morphology of filamentous bacteria [Poster presentation]. CHISA 2002 - 15th International Congress of Chemical and Process Engineering, Praha, Czechia.

Léonard, A., Blacher, S., Marchot, P., & Crine, M. (2002). Use of X-ray microtomography to follow the convective heat drying of wastewater sludges. Drying Technology, 20 (4-5), 1053-1069. doi:10.1081/DRT-120004013

Van Valckenborgh, E., De Raeve, H., Devy, L., Blacher, S., Munaut, C., Noël, A., Van Marck, E., Van Riet, I., Van Camp, B., & Vanderkerken, K. (2002). Murine 5T multiple myeloma cells induce angiogenesis in vitro and in vivo. British Journal of Cancer, 86 (5), 796-802. doi:10.1038/sj.bjc.6600137

Blacher, S., Devy, L., Burbridge, M. F., Roland, G., Tucker, G., Noël, A., & Foidart, J.-M. (2001). Improved Quantification of Angiogenesis in the Rat Aortic Ring Assay. Angiogenesis, 4 (2), 133-42. doi:10.1023/A:1012251229631

Blacher, S., Maquet, V., Pirard, R., Pirard, J.-P., & Jérôme, R. (2001). Image analysis, impedance spectroscopy and mercury porosimetry characterisation of freeze-drying porous materials. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 187-188, 375-383. doi:10.1016/S0927-7757(01)00652-5

Carmeliet, P., Moons, L., Luttun, A., Vincenti, Compernolle, V., De mol, M., Wu, Y., Bono, F., Devy, L., Beck, H., Scholz, D., Acker, T., Dipalma, T., Dewerchin, M., Noël, A., Stalmans, I., Barra, A., Blacher, S., Vandendriessche, T., ... Persico, G. (2001). Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions. Nature Medicine, 7 (5), 575-583. doi:10.1038/87904

Groslambert, S., Blacher, S., & Crine, M. (2001). Étude de l'influence de l'hydrodynamique sur une bactérie filamenteuse par analyse d'images. Récents Progrès en Génie des Procédés, 78 (18), 153-158.

Calberg, C., Blacher, S., Gubbels, F., Brouers, F., Deltour, R., & Jérôme, R. (1999). Electrical and dielectric properties of carbon black filled co-continuous two-phase polymer blends. Journal of Physics: D Applied Physics, 32 (13), 1517-1525. doi:10.1088/0022-3727/32/13/313

Tian, D., Blacher, S., Dubois, P., Pirard, J.-P., & Jérôme, R. (1998). Porous silica obtained from biodegradable and biocompatible inorganic-organic hybrid materials. Journal of Sol-Gel Science and Technology, 13 (1-3), 415-419. doi:10.1023/A:1008617126855

Brouers, F., Royen, I., Blacher, S., Pirard, R., Gubbels, F., Jérôme, R., & Sarychev, A. (1996). AC Properties of Carbon Black Filled Polymer Blends. Materials Research Society Symposia Proceedings, 411, 339-343.

Blacher, S., Brouers, F., Fayt, R., & Teyssié, P. (1993). Multifractal analysis. A new method for the characterization of the morphology of multicomponent polymer systems. Journal of Polymer Science. Part B, Polymer Physics, 31 (6), 655-662. doi:10.1002/polb.1993.090310605

Fayt, R., Harrats, C., Blacher, S., Jérôme, R., & Teyssié, P. (1993). Stability of co-continuous phase morphologies in emulsified polyethylene-polystyrene blends. Polymeric Materials: Science and Engineering, 69, 178-179.