Layios, N., Gosset, C., Maes, N., Delierneux, C., Hego, A., Huart, J., LECUT, C., DAMAS, P., Oury, C., & Gothot, A. (2023). Prospective flow cytometry analysis of leucocyte subsets in critically ill patients who develop sepsis: a pilot study. Infection. doi:10.1007/s15010-023-01983-3 |
KAUX, J.-F., Libertiaux, V., Dupont, L., Colige, A., Denoël, V., LECUT, C., Hego, A., Gustin, M., Duwez, L., Oury, C., Gothot, A., Greimers, L., & Drion, P. (February 2020). Platelet-rich plasma (PRP) and tendon healing: comparison between fresh and frozen-thawed PRP. Platelets, 31 (2), 221-225. doi:10.1080/09537104.2019.1595563 |
Roels, E., Bauer, N., LECUT, C., Moritz, A., GOTHOT, A., & Clercx, C. (29 October 2019). Haemostatic, fibrinolytic and inflammatory profiles in West Highland white terriers with canine idiopathic pulmonary fibrosis and controls. BMC Veterinary Research, 15 (1), 379. doi:10.1186/s12917-019-2134-z |
Wéra, O., LECUT, C., Servais, L., Hego, A., Delierneux, C., Jiang, Z., Keutgens, A., Evans, R. J., Delvenne, P., Lancellotti, P., & Oury, C. (21 August 2019). P2X1 ion channel deficiency causes massive bleeding in inflamed intestine and increases thrombosis. Journal of Thrombosis and Haemostasis, 18 (1), 44-56. doi:10.1111/jth.14620 |
Wéra, O., Servais, L., Delierneux, C., Hego, A., LECUT, C., KEUTGENS, A., Delvenne, P., Nchimi Longang, A., Lancellotti, P., & Oury, C. (November 2018). P2X1 deficiency causes massive intestinal bleeding along with enhanced neutrophil-dependent thrombosis in colitis [Paper presentation]. Belgian Society on Thrombosis and Haemostasis BSTH 2018. |
Kaux, J.-F., Libertiaux, V., Dupont, L., Colige, A., Denoël, V., LECUT, C., GOTHOT, A., Greimers, L., & Drion, P. (2018). Platelet-Rich Plasma (PRP) and tendon healing: comparison between fresh and frozen-thawed PRP. In Towards healthy tendon ageing (pp. 39-40). |
Kaux, J.-F., Libertiaux, V., Leprince, P., Fillet, M., Denoël, V., LECUT, C., Gothot, A., Le Goff, C., Croisier, J.-L., & Drion, P. (2018). Eccentric training for tendon healing after acute lesion: a rat model. In Towards healthy tendon ageing (pp. 45). |
Oury, C., Wéra, O., Servais, L., Lancellotti, P., Hego, A., LECUT, C., Nchimi Longang, A., & Delvenne, P. (September 2018). A novel P2X1-G-CSF-CCL5 axis controls hemostasis via platelets and neutrophils in intestinal inflammation [Paper presentation]. 4th European Platelet Network Meeting. |
Greimers, L., Drion, P., Colige, A., Libertiaux, V., Denoël, V., LECUT, C., Gothot, A., & Kaux, J.-F. (March 2018). Effects of Allogeneic Platelet-Rich Plasma (PRP) on the Healing Process of Sectioned Achilles Tendons of Rats: A Methodological Description. Journal of Visualized Experiments, 133, 55759. doi:10.3791/55759 |
Montague, S.* , Delierneux, C.* , LECUT, C., LAYIOS, N., Dinsdale, R., Lee, C., Poulter, N., Andrews, R., Hampson, P., Wearn, C., MAES, N., Bishop, J., Bamford, A., Gardiner, C., Lee, W., Iqbal, T., Moiemen, N., Watson, S., Oury, C.* , ... Gardiner, E.*. (February 2018). Soluble GPVI is elevated in injured patients: shedding is mediated by fibrin activation of GPVI. Blood, 2 (3), 240/251. doi:10.1182/bloodadvances.2017011171 * These authors have contributed equally to this work. |
Momozawa, Y., Dmitrieva, J. B., Theatre, E., Deffontaine, V., Rahmouni, S., Charloteaux, B., Crins, F., Elansary, M., Gori, A.-S., LECUT, C., Mariman, R., Mni, M., Oury, C., Altukhov, I., Alexeev, D., Aulchenko, Y., Amininejad, L., van der Meulen-de Jong, A. E., van der Woude, C. J., ... Georges, M. (2018). IBD risk loci are enriched in multigenic regulatory modules encompassing causative genes. Nature Communications. doi:10.1038/s41467-018-04365-8 |
LAYIOS, N., Delierneux, C., Hego, A., HUART, J., GOSSET, C., LECUT, C., MAES, N., Geurts, P., Joly, A., LANCELLOTTI, P., Albert, A., DAMAS, P., GOTHOT, A., & Oury, C. (December 2017). Sepsis prediction in critically ill patients by platelet activation markers on ICU admission: a prospective pilot study. Intensive Care Medicine Experimental, 5 (1), 32. doi:10.1186/s40635-017-0145-2 |
Wéra, O., Servais, L., Delierneux, C., Hego, A., LECUT, C., DELVENNE, P., Nchimi Longang, A., LANCELLOTTI, P., & Oury, C. (November 2017). P2X1 ion channel regulates neutrophil NETosis in colitis [Paper presentation]. BSTH 2017, Mechelen, Belgium. |
Wéra, O., Delierneux, C., Servais, L., Hego, A., LECUT, C., DELVENNE, P., Nchimi Longang, A., LANCELLOTTI, P., & Oury, C. (July 2017). Interplay between platelets, neutrophils and coagulation in bleeding in a mouse model of inflammatory bowel disease [Poster presentation]. ISTH 2017, Berlin, Germany. |
Delierneux, C., Donis, N., Servais, L., Wéra, O., LECUT, C., Vandereyken, M., Musumeci, L., Rahmouni, S., Schneider, J., Eble, J., LANCELLOTTI, P., & Oury, C. (May 2017). Targeting of C-type lectin-like receptor 2 or P2Y12 for the prevention of platelet activation by immunotherapeutic CpG oligodeoxynucleotides. Journal of Thrombosis and Haemostasis, 15 (5), 983-997. doi:10.1111/jth.13669 |
Kaux, J.-F., Libertiaux, V., Leprince, P., Fillet, M., Denoël, V., Wyss, C., LECUT, C., Gothot, A., Le Goff, C., Croisier, J.-L., Crielaard, J.-M., & Drion, P. (May 2017). Eccentric training for tendon healing after lesion: a rat model. American Journal of Sports Medicine, 45 (6), 1440-1446. doi:10.1177/0363546517689872 |
PETERS, P., LECUT, C., BOSSU, O., & GOTHOT, A. (25 November 2016). Performance evaluation of the new point-of-care coagulation analyzer Xprecia stride for measuring INR in VKA-treated patients – comparison with local laboratory automated reference method [Poster presentation]. 24ème congrès annuel de la Société belge de Thrombose Hémostase, Mechelen, Belgium. |
Wéra, O., Delierneux, C., Servais, L., Hego, A., LECUT, C., Nchimi Longang, A., Lancellotti, P., & Oury, C. (November 2016). P2X1 ion channel is critical for vascular integrity in inflammation [Poster presentation]. BSTH 2016, Mechelen, Belgium. |
Roels, E., Bauer, N., LECUT, C., Billen, F., Soete, C., Peters, P., Moritz, A., Gothot, A., & Clercx, C. (September 2016). Investigation of the coagulation system in canine idiopathic pulmonary fibrosis [Poster presentation]. 26 th ECVIM-CA congress, Goteborg, Sweden. |
Wéra, O., Delierneux, C., Hego, A., LECUT, C., Servais, L., Nchimi Longang, A., Lancellotti, P., & Oury, C. (September 2016). P2X1 ion channel is critical for vascular integrity in inflammation [Paper presentation]. 3rd EUPLAN Conference, Bad Homburg, Germany. |
LAGNY, M.-G., GOTHOT, A., HANS, G., KOCH, J.-N., BLAFFART, F., HELLA, D., Donneau, A.-F., ROEDIGER, L., LECUT, C., PINCEMAIL, J., CHERAMY-BIEN, J.-P., & DEFRAIGNE, J. (2016). Efficacy of the RemoweLL cardiotomy reservoir for fat and leucocyte removal from shed mediastinal blood: a randomized controlled trial. Perfusion. doi:10.1177/0267659116649427 |
Guffins, A., FARHAT, N., GKIOUGKI, E., LECUT, C., VAN LINTHOUT, C., Gothot, A., & Seghaye, M.-C. (2016). Role of inflammatory- and growth factors in the pathophysiology of gestational diabetes-related complications in neonates. Belgian Journal of Paediatrics, 18 (1), 82. |
Wéra, O., Delierneux, C., Hego, A., LECUT, C., Servais, L., Nchimi Longang, A., LANCELLOTTI, P., & Oury, C. (2016). P2X1 ion channel is critical for vascular integrity in inflammation [Poster presentation]. ESC CONGRESS, ROMA, Italy. |
LECUT, C., PETERS, P., FIORE, M., Delierneux, C., JOIRET, M., Hego, A., Oury, C., & GOTHOT, A. (20 November 2015). Phenotypic characterization of a patient with Glanzmann Thrombasthenia caused by a novel homozygous mutation in the ITGA2B gene [Poster presentation]. 23ème congrès annuel de la Société Belge de Thrombose-Hémostase, Mechelen, Belgium. |
Wéra, O., Delierneux, C., Hego, A., LECUT, C., Servais, L., LANCELLOTTI, P., & Oury, C. (November 2015). P2X1 ion channels limit the formation of extra-intestinal neutrophil-rich thrombi in acute colitis [Poster presentation]. Belgian Society of Thrombosis and Hemostasis, Mechelen, Belgium. |
Delierneux, C., LAYIOS, N., Hego, A., HUART, J., Joly, A., Geurts, P., DAMAS, P., LECUT, C., GOTHOT, A., & Oury, C. (19 October 2015). Elevated basal levels of platelet-bound fibrinogen predict the occurrence of sepsis in ICU: a prospective study [Paper presentation]. Belgian Society on Thrombosis and Haemostasis (BSTH), Lamot, Belgium. |
Delierneux, C., LAYIOS, N., Hego, A., HUART, J., Joly, A., Geurts, P., DAMAS, P., LECUT, C., GOTHOT, A., & Oury, C. (23 June 2015). Prospective analysis of platelet activation markers to predict severe infection and mortality in intensive care units [Poster presentation]. XXV Congress of the International Society on Thrombosis and Haemostasis (ISTH), Toronto, Canada. |
Delierneux, C., Hego, A., LECUT, C., Vandereyken, M., MUSUMECI, L., Rahmouni, S., BOURS, V., LANCELLOTTI, P., & Oury, C. (22 June 2015). CLEC-2 is required for the activation of mouseplatelets by bacterial DNA mimetics [Paper presentation]. ISTH 2015 Congress, Toronto, Canada. |
Delierneux, C., Hego, A., LECUT, C., Vandereyken, M., MUSUMECI, L., Rahmouni, S., BOURS, V., Lancellotti, P., & Oury, C. (22 June 2015). CLEC-2 is required for the activation of mouse platelets by bacterial DNA mimetics [Paper presentation]. ISTH 2015 Congress, Toronto, Canada. |
LECUT, C., PETERS, P., MASSION, P., & GOTHOT, A. (April 2015). Quelle place pour le test de génération de thrombine au sein du laboratoire de biologie clinique? Annales de Biologie Clinique, 73 (2), 137-149. doi:10.1684/abc.2014.1018 |
Kaux, J.-F., Bouvard, M., LECUT, C., Oury, C., GOTHOT, A., Mikel, S., & Crielaard, J.-M. (March 2015). Reflections about the optimisation of the treatment of tendinopathies with PRP. Muscles, Ligaments and Tendons Journal, 5 (1 (eCollection 2015 Jan-Mar)), 1-4. doi:10.11138/mltj/2015.5.1.001 |
Musumeci, L., Kuijpers, M., Gilio, K., Hego, A., Theatre, E., Maurissen, L., Vandereyken, M., Diogo, C., LECUT, C., Guilmain, W., Bobkova, E., Eble, J., Dahl, R., Drion, P., Rascon, J., Mostofi, Y., Yuan, H., Sergienko, E., Chung, T., ... Rahmouni, S.*. (17 February 2015). DUSP3 Phosphatase Deficiency or Inhibition Limit Platelet Activation and Arterial Thrombosis. Circulation, 131 (7), 656-68. doi:10.1161/CIRCULATIONAHA.114.010186 * These authors have contributed equally to this work. |
GOTHOT, A., GOSSET, C., LECUT, C., PETERS, P., & MASSION, P. (30 January 2015). Point-of-care devices assessing platelet function and clotting in sepsis: effect of thrombocytopenia and analytical variables [Poster presentation]. 30th General Annual Meeting of the Belgian Hematological Society. |
LECUT, C., CLOTUCHE, C., LAGNY, M.-G., PETERS, P., Defraigne, J.-O., GOTHOT, A., & LARBUISSON, R. (30 January 2015). Hepcon(R) HMS and Hemochron(R) allow for similar anticoagulation management during cardiopulmonary bypass in low-risk patients undergoing cardiac surgery [Poster presentation]. 30th General Annual Meeting of the Belgian Hematological Society. |
Delierneux, C., Hego, A., LECUT, C., Vandereyken, M., Musumeci, L., Rahmouni, S., Thiry, M., Compère, P., BOURS, V., Lancellotti, P., & Oury, C. (27 January 2015). Bacterial DNA mimetics activate platelets and promote thrombosis via CLEC-2 [Poster presentation]. GIGA-DAY: Current advances in medical genetics and genomics, Liège, Belgium. |
Oury, C., LECUT, C., Hego, A., Wéra, O., & Delierneux, C. (16 January 2015). Purinergic control of inflammation and thrombosis: Role of P2X1 receptors. Computational and Structural Biotechnology Journal, 13, 106-110. doi:10.1016/j.csbj.2014.11.008 |
LAYIOS, N., Delierneux, C., Hego, A., HUART, J., Joly, A., Geurts, P., DAMAS, P., LECUT, C., Gothot, A., & Oury, C. (2015). Erratum: Elevated basal levels of circulating activated platelets predict ICU-acquired sepsis and mortality: a prospective study. Critical Care, 19 (1), 301. doi:10.1186/s13054-015-1005-7 |
Darbousset, R., Delierneux, C., Mezouar, S., Hego, A., LECUT, C., Guillaumat, I., Riederer, M., Evans, R., Dignat-George, F., Panicot-Dubois, L., Oury, C., & Dubois, C. (16 October 2014). P2X1 expressed on polymorphonuclear neutrophils and platelets is required for thrombosis in mice. Blood, 124, 2575-2585. doi:10.1182/blood-2014-04-571679 |
LECUT, C., PETERS, P., & GOTHOT, A. (02 October 2014). Quelle place pour le test de génération de thrombine au sein du laboratoire de biologie clinique? [Paper presentation]. 2ème congrès de biologie clinique, Reims, France. |
Onselaer, M.-B., Oury, C., Hunter, R. W., Eeckhoudt, S., Barile, N., LECUT, C., Morel, N., Jacquet, L.-M., Bertrand, L., Sakamoto, K., Vanoverschelde, J.-L., Beauloye, C., & Horman, S. (June 2014). CAMKKβ/AMPK-α1 pathway regulates phosphorylation of cytoskeletal targets in thrombin-stimulated human platelets. Journal of Thrombosis and Haemostasis, 12 (6), 973-986. doi:10.1111/jth.12568 |
Gori, A.-S., LECUT, C., Theatre, E., Momozawa, Y., Docampo Martínez, E., Mariman, R., Dmitrieva, J. B., Elansary, M., Charloteaux, B., Defontaine, V., Mni, M., Crins, F., LOUIS, E., Georges, M., & Oury, C. (24 April 2014). Combined use of GWAS and eQTL information to identify genes controlling platelet biology [Poster presentation]. BeMGI. doi:10.13140/RG.2.1.4044.9763 |
Castanares-Zapatero, D., Bouleti, C., Sommereyns, C., Gerber, B., LECUT, C., Mathivet, T., Horckmans, M., Communi, D., Foretz, M., Vanoverschelde, J.-L., Germain, S., Bertrand, L., Laterre, P.-F., Oury, C., Viollet, B., Horman, S., & Beauloye, C. (December 2013). Connection between cardiac vascular permeability, myocardial oedema and inflammation during sepsis: role of the alpha1AMPK isoform. Critical Care Medicine, 41 (12), 411-22. |
GOTHOT, A., GOSSET, C., FOGUENNE, J., LECUT, C., DAMAS, P., Oury, C., & MASSION, P. (2013). Identification of biomarkers of hemostatic, endothelial and immune function in sepsis. Belgian Journal of Hematology. |
GOTHOT, A., GOSSET, C., FOGUENNE, J., LECUT, C., DAMAS, P., Oury, C., & MASSION, P. (2013). Identification of biomarkers of hemostatic, endothelial and immune function in sepsis [Poster presentation]. 28th General Annual Meeting of the Belgian Hematological Society, Gent, Belgium. |
Theatre, E., Frederix, K., Guilmain, W., Delierneux, C., Lecut, C., Bettendorff, L., BOURS, V., & Oury, C. (August 2012). Overexpression of CD39 in mouse airways promotes bacteria induced inflammation. Journal of Immunology, 189 (4), 1966-1974. doi:10.4049/jimmunol.1102600 |
Castanares-Zapatero, D., Overtus, M., Communi, D., Horckmans, M., Bertrand, L., Oury, C., LECUT, C., Laterre, P., De Man, S., Sommereyns, C., Horman, S., & Beauloye, C. (March 2012). AMP-activated protein kinase controls liposaccharide-induced hyperpermeability. Critical Care, 16 (suppl 1), 17. |
Lecut, C., Faccinetto, C., Delierneux, C., van Oerle, R., Spronk, H., Evans, R. J., El Benna, J., Bours, V., & Oury, C. (2012). ATP-gated P2X1 ion channels protect from endotoxemia by dampening neutrophil activation. Journal of Thrombosis and Haemostasis, 10 (3), 453-65. doi:10.1111/j.1538-7836.2011.04606.x |
Lecut, C., Faccinetto, C., Evans, R. J., BOURS, V., & Oury, C. (2011). Lack of P2X1 ion channels increases endotoxemia associated coagulation and organ damage through neutrophil hyperresponsiveness. Journal of Thrombosis and Haemostasis, 9 (suppl S2). |
Lecut, C., Frederix, K., Johnson, D. M., Deroanne, C., Thiry, M., Faccinetto, C., Marée, R., Evans, R. J., Volders, P. G., Bours, V., & Oury, C. (2009). P2X1 Ion Channels Promote Neutrophil Chemotaxis through Rho Kinase Activation. Journal of Immunology. doi:10.4049/jimmunol.0804007 |
Lecut, C., Frederix, K., Johnson, D., Faccinetto, C., Volders, P., Bours, V., & Oury, C. (2008). Contribution of ATP-gated P2X1 ion channels to the control of neutrophil chemotaxis. Purinergic Signalling, 4, 30. |
Faccinetto, C., Lecut, C., Jacobs, N., Bours, V., & Oury, C. (2007). P2X1 receptors as new regulators of neutrophil life span. Journal of Thrombosis and Haemostasis. |
Faccinetto, C., Lecut, C., Greimers, R., Bours, V., & Oury, C. (2006). New role for ATP P2X1 receptors in the control of neutrophil apoptosis and respiratory burst activity. Blood, 108 (11, Part 1), 1647. |
Cosemans, J. M. E. M., Kuijpers, M. J. E., Lecut, C., Loubele, S. T. B. G., Heeneman, S., Jandrot-Perrus, M., & Heemskerk, J. W. M. (2005). Contribution of platelet glycoprotein VI to the thrombogenic effect of collagens in fibrous atherosclerotic lesions. Atherosclerosis, 181 (1), 19-27. doi:10.1016/j.atherosclerosis.2004.12.037 |
Lecut, C., Feijge, M. A. H., Cosemans, J. M. E. M., Jandrot-Perrus, M., & Heemskerk, J. W. M. (2005). Fibrillar type I collagens enhance platelet-dependent thrombin generation via glycoprotein VI with direct support of alpha2beta1 but not alphaIIbbeta3 integrin. Thrombosis and Haemostasis, 94 (1), 107-14. doi:10.1160/TH04-12-0783 |
Lecut, C., Arocas, V., Ulrichts, H., Elbaz, A., Villeval, J.-L., Lacapere, J.-J., Deckmyn, H., & Jandrot-Perrus, M. (2004). Identification of residues within human glycoprotein VI involved in the binding to collagen: evidence for the existence of distinct binding sites. Journal of Biological Chemistry, 279 (50), 52293-9. doi:10.1074/jbc.M406342200 |
Lecut, C., Schoolmeester, A., Kuijpers, M. J. E., Broers, J. L. V., van Zandvoort, M. A. M. J., Vanhoorelbeke, K., Deckmyn, H., Jandrot-Perrus, M., & Heemskerk, J. W. M. (2004). Principal role of glycoprotein VI in alpha2beta1 and alphaIIbbeta3 activation during collagen-induced thrombus formation. Arteriosclerosis, Thrombosis and Vascular Biology, 24 (9), 1727-33. doi:10.1161/01.ATV.0000137974.85068.93 |
Nurden, P., Jandrot-Perrus, M., Combrie, R., Winckler, J., Arocas, V., Lecut, C., Pasquet, J.-M., Kunicki, T. J., & Nurden, A. T. (2004). Severe deficiency of glycoprotein VI in a patient with gray platelet syndrome. Blood, 104 (1), 107-14. doi:10.1182/blood-2003-11-3842 |
Lecut, C., Feeney, L. A., Kingsbury, G., Hopkins, J., Lanza, F., Gachet, C., Villeval, J.-L., & Jandrot-Perrus, M. (2003). Human platelet glycoprotein VI function is antagonized by monoclonal antibody-derived Fab fragments. Journal of Thrombosis and Haemostasis, 1 (12), 2653-62. doi:10.1111/j.1538-7836.2003.00495.x |
Lagrue-Lak-Hal, A. H., Debili, N., Kingbury, G., Lecut, C., Le Couedic, J. P., Villeval, J. L., Jandrot-Perrus, M., & Vainchenker, W. (2001). Expression and function of the collagen receptor GPVI during megakaryocyte maturation. Journal of Biological Chemistry, 276 (18), 15316-25. doi:10.1074/jbc.M009117200 |
Mounier, C. M., Luchetta, P., Lecut, C., Koduri, R. S., Faure, G., Lambeau, G., Valentin, E., Singer, A., Ghomashchi, F., Beguin, S., Gelb, M. H., & Bon, C. (2000). Basic residues of human group IIA phospholipase A2 are important for binding to factor Xa and prothrombinase inhibition comparison with other mammalian secreted phospholipases A2. European Journal of Biochemistry, 267 (16), 4960-9. doi:10.1046/j.1432-1327.2000.01523.x |