Koch, N., Jennotte, O., Lechanteur, A., DEVILLE, M., Charlier, C., Cardot Jean-Michel, CHIAP, P., & Evrard, B. (2024). An Intravenous Pharmacokinetic Study of Cannabidiol Solutions in Piglets through the Application of a Validated Ultra-High-Pressure Liquid Chromatography Coupled to Tandem Mass Spectrometry Method for the Simultaneous Quantification of CBD and Its Carboxylated Metabolite in Plasma. Pharmaceutics. doi:10.3390/pharmaceutics16010140 |
Lecomte, F.* , Aerts, J.* , Plenevaux, A., Defraiteur, C., Chappuis-Hugon, F., Rozet, E., CHIAP, P., Luxen, A., Pichon, V., Hubert, P.* , & Hubert, C.*. (20 February 2020). Performance evaluation of a MIP for the MISPE-LC determination of p-[18F]MPPF and a potential metabolite in human plasma. Journal of Pharmaceutical and Biomedical Analysis, 180. doi:10.1016/j.jpba.2019.113015 * These authors have contributed equally to this work. |
Sacré, P.-Y., deconinck, E., Daszykowski, M., Courselle, P., Vancauwenberghe, R., Chiap, P., Crommen, J., & De Beer, J. (22 June 2011). Impurity fingerprints for the identification of counterfeit medicines - a feasibility study [Poster presentation]. HPLC 2011, Budapest, Hungary. |
Sacré, P.-Y., Deconinck, E., Chiap, P., Crommen, J., Mansion, F., Rozet, E., Courselle, P., & De Beer, J. (20 June 2011). Development and validation of a UHPLC-UV method for the detection and quantification of erectile dysfunction drugs and some of their analogues found in counterfeit medicines [Poster presentation]. HPLC 2011, Budapest, Hungary. |
Sacré, P.-Y., Deconinck, E., Chiap, P., Crommen, J., Mansion, F., Rozet, E., Courselle, P., & De Beer, J. (2011). Development and validation of a ultra-high-performance liquid chromatography-UV method for the detection and quantification of erectile dysfunction drugs and some of their analogues found in counterfeit medicines. Journal of Chromatography. A, 1218, 6439-6447. doi:10.1016/j.chroma.2011.07.029 |
Sacré, P.-Y., Deconinck, E., Daszykowski, M., Courselle, P., Vancauwenberghe, R., Chiap, P., Crommen, J., & De Beer, J. (2011). Impurity fingerprints for the identification of counterfeit medicines - a feasibility study. Analytica Chimica Acta, 701, 224-231. doi:10.1016/j.aca.2011.05.041 |
Sacré, P.-Y.* , Deconinck, E.* , Saerens, L., De Beer, T., Courselle, P., Vancauwenberghe, R., Chiap, P., Crommen, J., & De Beer, J. (2011). Detection of counterfeit Viagra® by Raman Microspectroscopy imaging and multivariate analysis. Journal of Pharmaceutical and Biomedical Analysis, 56, 454-461. doi:10.1016/j.jpba.2011.05.042 * These authors have contributed equally to this work. |
Sacré, P.-Y., Deconinck, E., De Beer, T., Courselle, P., Vancauwenberghe, R., Chiap, P., Crommen, J., & De Beer, J. (23 September 2010). Comparison and combination of spectroscopic techniques for the detection of counterfeit medicines [Poster presentation]. Drug Analysis 2010, Anvers, Belgium. |
Rousseau, A., Chiap, P., Ivanyi, R., Crommen, J., Fillet, M., & Servais, A.-C. (2008). Validation of a nonaqueous capillary electrophoretic method for the enantiomeric purity determination of R-flurbiprofen using a single-isomer amino cyclodextrin derivative. Journal of Chromatography. A, 1204 (2), 219-225. doi:10.1016/j.chroma.2008.06.006 |
Lecomte, F., Aerts, J., Plenevaux, A., Lignon, S., Chapuis-Hugon, F., Chiap, P., Crommen, J., Luxen, A., Pichon, V., & Hubert, P. (September 2007). PPERFORMANCE EVALUATION OF TWO MIPS FOR THE SPE-LC-UV DETERMINATION OF p-[18F]MPPF IN PLASMA [Poster presentation]. RDPA 2007, 12th Internatioinal Meeting on Recent Developments in Pharmaceutical Analysis, Island of Elba, Italy. |
Hubert, C., streel, B., Sibenaler, R., Chiap, P., & Hubert, P. (July 2007). Development and pre-validation of a high sensitive method for the determination of levonorgestrel in human plasma by SPE/LC/MS-MS [Poster presentation]. 31th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Gand, Belgium. |
Lecomte, F., Aerts, J., Plenevaux, A., Lignon, S., Denjean, C., Chapuis-Hugon, F., Chiap, P., Crommen, J., Luxen, A., Pichon, V., & Hubert, P. (June 2007). DEVELOPMENT AND VALIDATION OF A METHOD FOR THE LC DETERMINATION p-[18F]MPPF IN PLASMA USING A MISPE [Poster presentation]. HPLC 2007 - 31st International Symposium on High Performance Liquid Phase Separations and Related Techniques, Ghent, Belgium. |
Marini Djang'Eing'A, R., Servais, A.-C., Rozet, E., Chiap, P., Boulanger, B., Rudaz, S., Crommen, J., Hubert, P., & Fillet, M. (June 2007). Enantiomeric purity testing of S-timolol by non-aqueous CE using heptakis(2,3-di-O-methyl-6-O-Sulfo)-β-cyclodextrin as chiral additive – Validation using the accuracy profile strategy and estimation of uncertainty [Poster presentation]. 31st International Symposium on HPLC and Related techniques, Gand, Belgium. |
Francois, Y., Varenne, A., Juillerat, E., Servais, A.-C., Chiap, P., & Gareil, P. (05 January 2007). Nonaqueous capillary electrophoretic behavior of 2-aryl propionic acids in the presence of an achiral ionic liquid - A chemometric approach. Journal of Chromatography. A, 1138 (1-2), 268-275. doi:10.1016/j.chroma.2006.10.063 |
Lecomte, F., Aerts, J., Houbart, V., Plenevaux, A., Lignon, S., Chiap, P., Crommen, J., Luxen, A., Pichon, V., & Hubert, P. (2007). EVALUATION DE DEUX POLYMERES A EMPREINTES MOLECULAIRES POUR LE DOSAGE DU p-[18F]MPPF DANS LE PLASMA [Poster presentation]. 7ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages - SEP07, Grenoble, France. |
Martin, G., Chiap, P., Paquet, P., Pierard, G., De Tullio, P., Martin, Y., Rozet, E., Hubert, P., Crommen, J., & Fillet, M. (2007). Development of a mass spectrometry method for the determination of a melanoma biomarker, 5-S-cysteinyldopa, in human plasma using solid phase extraction for sample clean-up. Journal of Chromatography. A, 1156 (1-2), 141-8. doi:10.1016/j.chroma.2006.12.088 |
Marini Djang'Eing'A, R., Chiap, P., Boulanger, B., Rudaz, S., Rozet, E., Crommen, J., & Hubert, P. (November 2006). Comparaison de trois approches pour l'estimation de l'incertitude [Paper presentation]. 3ème journée internationale de toxicologie hospitalière, Liège, Belgium. |
Lecomte, F., Aerts, J., Plenevaux, A., Lignon, S., Haber, G., Boulanger, B., Chiap, P., Luxen, A., & Hubert, P. (September 2006). EVALUATION OF MOLECULARLY IMPRINTED POLYMERS BY MEANS OF EXPERIMENTAL DESIGN PRIOR TO THE DETERMINATION OF p-[18F]MPPF IN PLASMA [Poster presentation]. MIP2006 - Fourth International Workshop on Molecularly Imprinted Polymers, Cardiff, United Kingdom. |
Piette, M., Evrard, B., Frankenne, F., Chiap, P., Bertholet, P., Castagne, D., Foidart, J.-M., Delattre, L., & Piel, G. (June 2006). Pharmacokinetic study of a new synthetic MMP inhibitor (Ro 28-2653) after IV and oral administration of cyclodextrin solutions. European Journal of Pharmaceutical Sciences, 28 (3), 189-195. doi:10.1016/j.ejps.2006.01.011 |
Marini Djang'Eing'A, R., Rozet, E., Ziemons, E., Chiap, P., Boulanger, B., Rudaz, S., Servais, A.-C., Fillet, M., Crommen, J., & Hubert, P. (May 2006). COMPARISON OF THREE DIFFERENT APPROACHES FOR UNCERTAINTY ESTIMATION CONSIDERING LC AND CE METHODS [Paper presentation]. A joint meeting of two distinguished series: the 8th International Symposium on Drug Analysis and the 17th International Symposium on Pharmaceutical and Biomedical Analysis, Namur, Belgium. |
Lecomte, F., Boulanger, B., Hall, A. J., Sellergren, B., Crommen, J., Chiap, P., & Hubert, P. (March 2006). Développement d’une méthode de dosage automatisé du méthotrexate dans le plasma humain par couplage direct à la chromatographie liquide de l’extraction sur phase solide à empreintes moléculaires [Poster presentation]. Forum LABO & Forum BIOTECH 2006, Paris, France. |
Servais, A.-C.* , Fillet, M.* , Mol, R., Somsen, G. W., Chiap, P., de Jong, G. J., & Crommen, J. (February 2006). On-line coupling of cyclodextrin mediated nonaqueous capillary electrophoresis to mass spectrometry for the determination of salbutamol enantiomers in urine. Journal of Pharmaceutical and Biomedical Analysis, 40 (3), 752-757. doi:10.1016/j.jpba.2005.08.004 * These authors have contributed equally to this work. |
Rozet, E., Boulanger, B., Dewe, W., Chiap, P., Moonen, F., Govaerts, B., Crommen, J., & Hubert, P. (2006). GERER LE RISQUE LORS DE LA VALIDATION DES METHODES ANALYTIQUES : APPLICATION A LA DETERMINATION D’IMPURETES [Paper presentation]. Congrès des Sciences Analytiques, Marrakech, Morocco. |
Lecomte, F., Boulanger, B., Hall, A. J., Sellergren, B., Rozet, E., Crommen, J., Chiap, P., & Hubert, P. (September 2005). OPTIMIZATION OF MOLECULARLY IMPRINTED SOLID-PHASE EXTRACTION BY MEANS OF EXPERIMENTAL DESIGN PRIOR TO THE DETERMINATION OF METHOTREXATE IN HUMAN PLASMA [Poster presentation]. RDPA 2005 - 11th International Meeting on Recent Developments in Pharmaceutical Analysis, Rimini, Italy. |
Lecomte, F., Hall, A. J., Sellegren, B., Crommen, J., Hubert, P., & Chiap, P. (June 2005). Evaluation of molecularly imprinted polymers for selective extraction of methotrexate from human plasma prior to its LC determination [Poster presentation]. HPLC 2005 - 29th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Stockholm, Sweden. |
Servais, A.-C., Fillet, M., Chiap, P., Dewé, W., Hubert, P., & Crommen, J. (11 March 2005). Influence of the nature of the electrolyte on the chiral separation of basic compounds in nonaqueous capillary electrophoresis using heptakis(2,3-di-O-methyl-6-O-sulfo)-beta-cyclodextrin. Journal of Chromatography. A, 1068 (1), 143-150. doi:10.1016/j.chroma.2004.12.010 |
Chiap, P., Piette, M., Evrard, B., Frankenne, F., Christiaens, B., Piel, G., Cataldo, D., Foidart, J.-M., Delattre, L., Crommen, J., & Hubert, P. (05 March 2005). Automated method for the determination of a new matrix metalloproteinase inhibitor in ovine plasma and serum by coupling of restricted access material for on-line sample clean-up to liquid chromatography. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 817 (1), 109-117. doi:10.1016/j.jchromb.2004.08.042 |
Rozet, E., Dewé, W., Chiap, P., Lecomte, F., & Hubert, P. (2005). Le transfert d’une méthode de dosage automatisée de 3 catécholamines majeures dans l’urine humaine: utilisation de l’erreur totale comme critère de décision [Paper presentation]. 3èmes Journées Internationales de Toxicologie Hospitalière, Liege, Belgium. |
Christians, B., Fillet, M., Chiap, P., Rbeida, O., Ceccato, A., Streel, B., De Graeve, J., Crommen, J., & Hubert, P. (2004). Fully automated method for the liquid chromatographic-tandem mass spectrometric determination of cyproterone acetate in human plasma using restricted access material for on-line sample clean-up. Journal of Chromatography. A, 1056 (1-2), 105-10. |
Marini Djang'Eing'A, R., Chiap, P., Hubert, P., & Crommen, J. (25 May 2001). Separation and simultaneous determination of S-timolol maleate, its optical antipode and related substances by liquid chromatography using a cellulose based chiral stationary phase [Paper presentation]. 10th Forum of Pharmaceutical Sciences, Montréal, Canada. |
Marini Djang'Eing'A, R., Pantella, A., Chiap, P., Bimazubute, M. A., Hubert, P., & Crommen, J. (April 2000). Development and validation of an LC method for the determination of six corticosteroids, salicylic acid and parabens in different pharmaceutical formulations [Paper presentation]. IXth Forum of Pharmaceutical Sciences, Blankenberge, Belgium. |
Fotsing, L., Boulanger, B., Chiap, P., Fillet, M., Hubert, P., & Crommen, J. (2000). Multivariate optimization approach for the separation of water-soluble vitamins and related compounds by capillary electrophoresis. Biomedical Chromatography: BMC, 14 (1), 10-1. doi:10.1002/(SICI)1099-0801(200002)14:1<10::AID-BMC947>3.0.CO;2-8 |
Fotsing, L., Fillet, M., Chiap, P., Hubert, P., & Crommen, J. (1999). Elimination of adsorption effects in the analysis of water-soluble vitamins in pharmaceutical formulations by capillary electrophoresis. Journal of Chromatography. A, 853 (1-2), 391-401. doi:10.1016/S0021-9673(99)00524-5 |
Duvivier, D. H., Chiap, P., Crommen, J., & Lekeux, P. (1997). Evaluation of some parameters influencing the drug delivery from a dry powder inhalation device using an in vitro model of the horse airways. Veterinary Research, 28 (6), 557-564. |
Streel, B., Ceccato, A., Chiap, P., Hubert, P., & Crommen, J. (1995). Injection-generated solvent and pH gradients for sample enrichment on injection of large volumes in microclumn liquid chromatography. Biomedical Chromatography: BMC, 9, 254-256. |