Publications and communications of Emilie CASTERMANS

Gordon, D. M., Beckers, P., CASTERMANS, E., Neggers, S. J., ROSTOMYAN, L., Bours, V., Pétrossians, P., Dideberg, V., Beckers, A., & Daly, A. (01 December 2021). Dutch Founder SDHB Exon 3 Deletion in Patients with Pheochromocytoma-Paraganglioma in South Africa. Endocrine Connections, 11 (1). doi:10.1530/EC-21-0560

PETIGNOT, S., Daly, A., CASTERMANS, E., Korpershoek, E., Scagnol, I., BECKERS, P., Dideberg, V., Rohmer, V., Bours, V., & Beckers, A. (2020). Pancreatic neuroendocrine neoplasm associated with a familial MAX deletion. Hormone and Metabolic Research. doi:10.1055/a-1186-0790

Daly, A., Cano, D. A., Venegas, E., PETROSSIANS, P., Dios, E., CASTERMANS, E., Flores-Martinez, A., Bours, V., Beckers, A., & Soto, A. (2019). AIP and MEN1 mutations and AIP immunohistochemistry in pituitary adenomas in a tertiary referral center. Endocrine Connections. doi:10.1530/EC-19-0027

Parotte, M.-C., CASTERMANS, E., Bours, V., Beckers, A., & VALDES SOCIN, H. G. (September 2018). Hypercalcémie familiale bénigne révélée par des crises de colique néphrétique : description d'une nouvelle mutation du calcium sensing receptor (CasR) [Poster presentation]. 35ème Congrès de la Société Française d'Endocrinologie, Nancy, France.

Daly, A.* , CASTERMANS, E.* , Oudijk, L., Guitelman, M. A., BECKERS, P., NECHIFOR, I., Neggers, S. J. C. M. M., SACRE, N., Van der Lely, A. J., Bours, V., de Herder, W. W., & Beckers, A. (13 March 2018). Pheochromocytomas and pituitary adenomas in three patients with MAX exon deletions. Endocrine-Related Cancer, 25 (5), 37–42. doi:10.1530/ERC-18-0065

Descamps, O. S., Van Caenegem, O., Hermans, M., Balligand, J.-L., Beauloye, C., Bondue, A., Carlier, S., CASTERMANS, E., Chenot, F., Claeys, M., De Block, C., de Leener, A., De Meester, A., Demeure, F., De Raedt, H., Desmet, W., Elegeert, I., Guillaume, M., Hoffer, E., ... Belgian Atherosclerosis Society/Belgian Lipid Club (BAS/BLC), T. B. S. O. C. B. S. C. A. T. R. B. S. O. L. M. R. (2018). A Belgian consensus strategy to identify familial hypercholesterolaemia in the coronary care unit and its subsequent cascade screening and treatment: BEL-FaHST (The BELgium Familial Hypercholesterolaemia STrategy). Atherosclerosis, 277, 369-376. doi:10.1016/j.atherosclerosis.2018.05.037

Rostomyan, L., Daly, A., Pellegata, N., NECHIFOR, I., BETEA, D., CASTERMANS, E., Christ., E., & BECKERS, A. (2017). Long-term management of resistant acromegaly with pasireotide LAR in 2 cases with a familial AIP Mutation. In Acta Clinica Belgica.

Rostomyan, L., Daly, A., Yuan, B., Fina, F., CABERG, J.-H., Trivellin, G., de Herder, W., Naves, L., Metzger, D., Cuny, T., Rabl, W., Shah, N., Jaffrain-Rea, M., Zatelli, M., Faucz, F., CASTERMANS, E., Nanni-Metellus, I., Lodish, M., Muhammad, A., ... Beckers, A. (2017). Somatic mosaicism is implicated in the etiology of XLAG syndrome. In Abstract book : Symposium "Perspectives in Endocrinology".

Rostomyan, L., Daly, A., Yuan, B., Fina, F., CABERG, J.-H., Trivellin, G., de Herder, W., Naves, L. A., Metzger, D., Cuny, T., Rabl, W., Shah, N., Jaffrain-Rea, M., Zatelli, M., Faucz, F., CASTERMANS, E., Nanni-Metellus, I., Lodish, M., Muhammad, A., ... Beckers, A. (2016). Somatic mosaicism is implicated in the etiology of XLAG syndrome. In 26nd meeting of the Belgian Endocrine Society - Abstract book.

Mangupli, R.* , Rostomyan, L.* , CASTERMANS, E., CABERG, J.-H., Camperos, P., Krivoy, J., Cuauro, E., BOURS, V., Daly, A., & BECKERS, A. (2016). Combined treatment with octreotide LAR and pegvisomant in patients with pituitary gigantism: clinical evaluation and genetic screening. Pituitary. doi:10.1007/s11102-016-0732-3

Rostomyan, L., Mangupli, R., CASTERMANS, E., CABERG, J.-H., Camperos, P., Krivoy, J., Cuaruo, E., Bours, V., Daly, A., & BECKERS, A. (May 2016). Combined treatment with octreotide LAR and pegvisomant in patients with gigantism – acromegaly: clinical evaluation and genetic screening [Poster presentation]. European Congress of Endocrinology, Munich, Germany. doi:10.1530/endoabs.41.EP889

Daly, A., Yuan, B., Fina, F., CABERG, J.-H., Trivellin, G., Rostomyan, L., de Herder, W. W., Naves, L. A., Metzger, D., Cuny, T., Rabl, W., Shah, N. S., Jaffrain-Rea, M.-L., Zatelli, M. C., Faucz, F. R., CASTERMANS, E., Nanni-Metellus, I., Lodish, M., Muhammad, A., ... BECKERS, A. (02 March 2016). Somatic mosaicism underlies X-linked acrogigantism (XLAG) syndrome in sporadic male subjects. Endocrine-Related Cancer, 23 (4), 221-233. doi:10.1530/ERC-16-0082

Castinetti, F.* , Daly, A.* , Stratakis, C., CABERG, J.-H., CASTERMANS, E., Trivellin, G., Rostomyan, L., Saveanu, A., Jullien, N., Reynaud, R., Barlier, A., Bours, V., Brue, T., & Beckers, A. (2016). GPR101 mutations are not a frequent cause of congenital isolated growth hormone deficiency. Hormone and Metabolic Research, 1-5. doi:10.1055/s-0042-100733

Daly, A., Lysy, P., Defilles, C., Rostomyan, L., Mohamed, A., CABERG, J.-H., Raverot, V., CASTERMANS, E., Marbaix, E., Maiter, D., Brunelle, C., Trivellin, G., Stratakis, C. A., BOURS, V., Raftopoulos, C., Beauloye, V., Barlier, A., & BECKERS, A. (2016). Growth hormone releasing hormone excess and blockade in X-LAG syndrome. Endocrine-Related Cancer. doi:10.1530/ERC-15-0478

Potorac, I., BETEA, D., MALAISE, O., Daniel, S., CASTERMANS, E., Bours, V., Daly, A., & Beckers, A. (2016). Une forme compliquée d'hypercalcémie hypocalciurique familiale. In Abstract book - Symposium "Perspectives in Endocrinology".

Rostomyan, L., Lysy, P., Desfilles, C., Trivellin, G., CABERG, J.-H., Mohamed, A., Raverot, V., Mantovani, G., Naves, L., Cheetham, T., Shah, N. S., Metzger, D., Zatelli, M., Strebkova, N., Mazerkina, N., Lodish, M., Marbaix, E., Maiter, D., Brunelle, C., ... Beckers, A. (2016). The genetic causes of pituitary gigantism. In Abstract book - Symposium "Perspectives in Endocrinology".

CASTERMANS, E., Auriemma, R., Rostomyan, L., SACRE, N., CABERG, J.-H., Bours, V., Daly, A., & Beckers, A. (2015). Etude moléculaire du gène AIP sur plus de 1400 individus atteints d'adénome hypophysaire. In Abstract book - Annales d'Endocrinologie - 32ème Congrès de la Société Française d'Endocrinologie.

Potorac, I., BETEA, D., MALAISE, O., Daniel, S., CASTERMANS, E., Bours, V., Daly, A., & Beckers, A. (2015). Une forme compliquée d'hypercalcémie hypocalciurique familiale. In Abstract book - Annales d'Endocrinologie - 32ème Congrès de la Société Française d'Endocrinologie.

Potorac, I., BETEA, D., PETROSSIANS, P., CASTERMANS, E., HAMOIR, E., Labasse, J., Bours, V., Daly, A., & Beckers, A. (2015). Hyperparathyroïdie primaire familiale isolée - corrélation génotype - phénotype des mutations MEN 1? In Abstract book - Annales d'Endocrinologie - 32ème Congrès de la Société Française d'Endocrinologie.

Rostomyan, L., Daly, A., PETROSSIANS, P., Trivellin, G., Shah, N., Mantovani, G., Neggers, S., CASTERMANS, E., CABERG, J.-H., Chanson, P., Zacharieva, S., Naves, L., & Beckers, A. (2015). The genetic causes of pituitary gigantism. In Endocrine Abstracts.

Daly, A., Lodish, M., Trivellin, G., Rostomyan, L., Faucz, F., Yuan, B., Naves, L. A., Choong, C., Lysy, P., Shah, N. S., Verrua, E., CABERG, J.-H., CASTERMANS, E., Zatelli, C., Schernthaner-Reiter, M., Villa, C., Metzger, D., Strebkova, N., Mazerkina, N., ... Beckers, A. (2015). Disease characteristics of patients with X-linked acrogigantism (X-LAG) syndrome. In Abstract book - ENDO 2015.

Stratakis, C., Trivellin, G., Rostomyan, L., Lodish, M., Faucz, F., Naves, L. A., Choong, C., Lysy, P., Shah, N. S., Verrua, E., CABERG, J.-H., CASTERMANS, E., JAMAR, M., Zatelli, M., Schernthaner-Reiter, M., Villa, C., Metzger, D., Strebkova, N., Mazerkina, N., ... Beckers, A. (2015). X-Linked acro-gigantism (X-LAG) syndrome : a new form of infant-onset pituitary gigantism. In Abstract book - 14th International Pituitary Congress.

Trivellin, G., Daly, A., Faucz, F., Yuan, B., Rostomyan, L., Larco, D., Schernthaner-Reiter, M., Szarek, E., Leal, L., CABERG, J.-H., CASTERMANS, E., Villa, C., Dimopoulos, A., Chittiboina, P., Xekouki, P., Shah, N. S., Metzger, D., Lysy, P., Ferrante, E., ... Stratakis, C. (2015). X-Linked acro-gigantism (X-LAG) due to microduplications of chromosome Xq26 : A new disorder and implications for acromegaly. In Abstract book - ENDO 2015.

Beckers, A.* , Lodish, M.* , Trivellin, G., Rostomyan, L., Lee, M., Faucz, F., Yuan, B., Choong, C., CABERG, J.-H., Verrua, E., Naves, L. A., Cheetham, T., Young, J., Lysy, P., PETROSSIANS, P., Cotterill, A., Shah, N. S., Metzger, D., CASTERMANS, E., ... Stratakis, C.*. (2015). X-linked acrogigantism syndrome : Clinical Profile and Therapeutic responses. Endocrine-Related Cancer, 22, 353-367. doi:10.1530/ERC-15-0038

Rostomyan, L.* , Daly, A.* , PETROSSIANS, P., Natchev, E., Lila, A. R., Lecoq, A.-L., Lecumberri Santamaria, B., Trivellin, G., Salvatori, R., Moraitis, A., Holdaway, I., Kranenburg-Van Klaveren, D., Zatelli, M. C., Palacios, N., Nozieres, C., Zacharin, M., Ebeling, T. M. L., Ojaniemi, M., Rozhinskaya, L., ... Beckers, A. (2015). Clinical and genetic characterization of pituitary gigantism: an international collaborative study in 208 patients. Endocrine-Related Cancer. doi:10.1530/ERC-15-0320

Thevenon, J., Bourredjem, A., Faivre, L., Bauters, C., Calender, A., Lebras, M., Giraud, S., Niccoli, P., Odou, M.-F., Borson-Chazot, F., Barlier, A., Lombard-Bohas, C., Clauser, E., Tabarin, A., Pasmant, E., Chabre, O., CASTERMANS, E., Ruszniewski, P., Bertherat, J., ... Goudet, P. (2015). Unravelling the intra-familial correlations and heritability of tumor types in MEN1, a GTE study. European Journal of Endocrinology, 173 (6), 819-826. doi:10.1530/EJE-15-0691

VALDES SOCIN, H. G., Daly, A., Burlacu, C., CHAVEZ, V., CASTERMANS, E., DIDEBERG, V., HAMOIR, E., BISOGNI, C., BETEA, D., Bours, V., & Beckers, A. (2014). Le cancer thyroïdien papillaire familial (FNMTC): études cliniques et génétiques chez 8 familles. In Abstract book - Annales d'Endocrinologie : 31ème Congrès de la Société Française d'Endocrinologie, Lyon 5-8 novembre 2014.

Hanssen, O., CASTERMANS, E., BOVY, C., WEEKERS, L., ERPICUM, P., DUBOIS, B., Bours, V., Krzesinski, J.-M., & Jouret, F. (2014). Two novel mutations of the CLDN16 gene cause familial hypomagnesaemia with hypercalciuria and nephrocalcinosis. NDT Plus, 7, 282-285. doi:10.1093/ckj/sfu019

Trivellin, G.* , Daly, A.* , Faucz, F. R., Yuan, B., Rostomyan, L., Larco, D. O., Schernthaner-Reiter, M. H., Szarek, E., Leal, L. F., CABERG, J.-H., CASTERMANS, E., Villa, C., Dimopoulos, A., Chittiboina, P., Xekouki, P., Shah, N. S., Metzger, D., Lysy, P. A., Ferrante, E., ... Stratakis, C. A.*. (2014). Gigantism and Acromegaly Due to Xq26 Microduplications and GPR101 Mutation. New England Journal of Medicine. doi:10.1056/NEJMoa1408028

Zatelli, M. C., Tagliati, F., Di Ruvo, M., CASTERMANS, E., Cavazzini, L., Daly, A., Ambrosio, M. R., Beckers, A., & Degli Uberti, E. (2014). Deletion of exons 1-3 of the MEN1 gene in a large Italian family causes the loss of menin expression. Familial Cancer. doi:10.1007/s10689-014-9702-y

Rostomyan, L., Potorac, I., CASTERMANS, E., Daly, A., & Beckers, A. (2013). A giant treated with growth hormone. In The 3rd ENEA Workshop : Hypopituitarism - Abstract book (pp. 97).

Bothra, N., Daly, A., CASTERMANS, E., Jagtap, V., Buydal, S., Lila, A., Bandgar, T., Rostomyan, L., Potorac, I., BOURS, V., Shah, N., & Beckers, A. (October 2013). FIPA : étude clinique et génétique à l'Hôpital "King Edward Memorial", Bombay (Mumbai) Inde. Annales d'Endocrinologie, 74, 443.

Bruck, F.* , Belle, L.* , LECHANTEUR, C., de Leval, L., Hannon, M., DUBOIS, S., CASTERMANS, E., Humblet-Baron, S., Rahmouni, S., Beguin, Y., BRIQUET, A.* , & Baron, F.*. (March 2013). Impact of bone marrow-derived mesenchymal stromal cells on experimental xenogeneic graft-versus-host disease. Cytotherapy, 15 (3), 267-279. doi:10.1016/j.jcyt.2012.09.003

CASTERMANS, E., GAILLEZ, S., & BOURS, V. (2013). Existe-t-il une predisposition genetique aux addictions ? Revue Médicale de Liège, 68 (5-6), 226-32.

Thevenon, J., Bourredjem, A., Faivre, L., Cardot-Bauters, C., Calender, A., Murat, A., Giraud, S., Niccoli, P., Odou, M.-F., Borson-Chazot, F., Barlier, A., Lombard-Bohas, C., Clauser, E., Tabarin, A., Parfait, B., Chabre, O., CASTERMANS, E., BECKERS, A., Ruszniewski, P., ... Goudet, P. (2013). Higher risk of death among MEN1 patients with mutations in the JunD interacting domain. A Groupe d'étude des Tumeurs Endocrines (GTE) cohort study. Human Molecular Genetics. doi:10.1093/hmg/ddt039

Jaffrain-Rea, M.-L., ANGELINI, M., OCCHI, G., TURCHI, A., CASTERMANS, E., CECCATO, F., ARCELLA, A., ESPOSITO, V., GIANGASPERO, F., PENNELLI, G., Daly, A., ALESSE, E., SCARONI, C., & Beckers, A. (2012). Ary Hydrocarbon receptor interacting protein (AIP) on somatotroph adenomas : a molecular target for somatostatin analogues ? In Endocrine abstracts - May 2012, volume 29.

Bruck, F., de Leval, L., Belle, L., LECHANTEUR, C., Hannon, M., BRIQUET, A., Dubois, S., CASTERMANS, E., Humblet-Baron, S., Rahmouni, S., BEGUIN, Y., & BARON, F. (2012). Bone marrow-derived mesenchymal stromal cells failed to prevent experimental xenogeneic graft-versus-host disease [Poster presentation]. Belgian Hematological Society General Annual Meeting.

Tichomirowa, M., Lee, M., Barlier, A., Daly, A., Marinoni, I., Jaffrain-Rea, M.-L., Naves, L. A., Rodien, P., Rohmer, V., Faucz, F. R., Caron, P., Estour, B., Lecomte, P., Borson-Chazot, F., Penfornis, A., Yaneva, M., Guitelman, M., CASTERMANS, E., Verhaege, C., ... Beckers, A. (2012). Cyclin dependent kinase inhibitor (CDKN1B) gene variants in AIP mutation-negative familial isolated pituitary adenomas (FIPA) kindreds. Endocrine-Related Cancer, 19, 233-241. doi:10.1530/ERC-11-0362

Schulte, I., Hitziger, T., Giugliano, S., Timm, J., Heinemann, F. M., Khudyakov, Y., Strasser, M., König, C., CASTERMANS, E., Mok, J. Y., van Esch, W. J., Bertoletti, A., Schumacher, T. N., & Roggendorf, M. (February 2011). Characterization of CD8+ T-cell response in acute and resolved hepatitis A virus infection. Journal of Hepatology, 54 (2), 201-208. doi:10.1016/j.jhep.2010.07.010

CASTERMANS, E., Hannon, M., Dutrieux, J., Humblet, S., Seidel, L., Cheynier, R., Willems, E., Gothot, A., Vanbellinghen, J.-F., Geenen, V., Sandmaier, B. M., Storb, R., Beguin, Y., & Baron, F. (2011). Thymic recovery after allogeneic hematopoietic cell transplantation with nonmyeloablative conditioning is limited to patients younger than 60 years of age. Haematologica, 96(2), 298-306. doi:10.3324/haematol.2010.029702

Reker Hadrup, S., Bakker, A. H., Shu, C. J., Andersen, R. S., van Veluw, J., Hombrink, P., Castermans, E., Straten, P. T., Blank, C., Haanen, J. B., Heemskerk, M. H., & Schumacher, T. N. (July 2009). Parallel detection of antigen-specific T-cell responses by multidimensional encoding of peptide-Major Histocompatibility Complexes. Nature Methods, 6 ((7)), 520-526. doi:10.1038/nmeth.1345

Humblet-Baron, S., CASTERMANS, E., Vanbellinghen, J.-F., Hannon, M., Jacobs, N., WILLEMS, E., Ormenese, S., Beguin, Y., & Baron, F. (February 2009). What Is The Role For Regulatory T-Cells After Nonmyeloablative Conditioning? Biology of Blood and Marrow Transplantation, 15 (2), 122-123. doi:10.1016/j.bbmt.2008.12.377

Castermans, E., Hannon, M., Drion, P., Geenen, V., Beguin, Y., & Baron, F. (2009). Reconstitution du système immunitaire après allogreffe de cellules souches hématopoïétiques. Revue Médicale de Liège, 64 (S1), 2-8.

Castermans, E. (2008). Contribution à l'étude de la reconstitution immunitaire après miniallogreffe de cellules souches hématopoïétiques [Doctoral thesis, Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/315296

Humblet-Baron, S., CASTERMANS, E., Vanbellighen, J.-F., Hannon, M., Jacobs, N., Beguin, Y., & Baron, F. (February 2008). What is the Role for Regulatory T-Cells after Nonmyeloablative conditioning. Biology of Blood and Marrow Transplantation, 14 (2), 136-137. doi:10.1016/j.bbmt.2007.12.383

Castermans, E.* , Baron, F.* , Willems, E., Schaaf-Lafontaine, N., Meuris, N., Gothot, A., Vanbellinghen, J.-F., Herens, C., Seidel, L., Geenen, V., Cheynier, R., & Beguin, Y. (2008). Evidence for neo-generation of T cells by the thymus after non-myeloablative conditioning. Haematologica, 93 (2), 240-7. doi:10.3324/haematol.11708

Castermans, E., Morrhaye, G., Marchand, S., Martens, H., Moutschen, M., Baron, F., Beguin, Y., & Geenen, V. (2007). Evaluation clinique de la fonction du thymus. Revue Médicale de Liège, 62 (11), 675-8.

Castermans, E., Morrhaye, G., Marchand, S., Martens, H., Moutschen, M., Geenen, V., Beguin, Y., & Baron, F. (2007). Evaluation de la thymopoiese: applications cliniques. Revue Médicale de Liège, 62 (12), 725-9.

Olivier, S., Close, P., Castermans, E., de Leval, L., Tabruyn, S., Chariot, A., Malaise, M., Merville, M.-P., Bours, V., & Franchimont, N. (May 2006). Raloxifene-induced myeloma cell apoptosis: a study of nuclear factor-kappaB inhibition and gene expression signature. Molecular Pharmacology, 69 (5), 1615-1623. doi:10.1124/mol.105.020479

Castermans, E., Baron, F., Willems, E., Meuris, N., Schaaf-Lafontaine, N., Reynier, R., Geenen, V., & Beguin, Y. (2006). Immune reconstitution after CD8-depleted or unmanipulated peripheral blood stem cells transplantation with nonmyeloablative conditioning. Acta Clinica Belgica, 61 (2), 113.

Pirson, L.* , Baron, F.* , Meuris, N., Giet, O., Castermans, E., Greimers, R., Di Stefano, I., Gothot, A., & Beguin, Y. (2006). Despite inhibition of hematopoietic progenitor cell growth in vitro, the tyrosine kinase inhibitor imatinib does not impair engraftment of human CD133+ cells into NOD/SCIDbeta2mNull mice. Stem Cells, 24 (7), 1814-21. doi:10.1634/stemcells.2005-0290

WILLEMS, E., CASTERMANS, E., Baron, F., BAUDOUX, E., Wanten, N., Bonnet, C., HAFRAOUI, K., Frère, P., Fillet, G., & Beguin, Y. (2006). Nonmyeloablative stem cell transplantation with CD8-depleted or unmalipulated peripheral blood stem cells: a prospective randomized trial [Paper presentation]. 21st General Meeting of the Belgian Hematological Society.

Olivier, S., Close, P., Castermans, E., de Leval, L., Tabruyn, S., Chariot, A., Malaise, M., Merville, M.-P., Bours, V., & Franchimont, N. (September 2005). SERMs-induced myeloma cell apoptosis: A study of NF-kappa B inhibition and gene expression signature. Journal of Bone and Mineral Research, 20 (9, Suppl. 1), 213.

Pirson, L., Baron, F., Meuris, N., Giet, O., Castermans, E., Greimers, R., Di Stefano, I., Gothot, A., & Beguin, Y. (2005). Despite inhibition of hematopoietic progenitor cell growth in vitro, the tyrosine kinase inhibitor imatinib does not impair engraftment of human CD133+ cells into NOD/SCIDBeta2mNull [Poster presentation]. 20th general meeting of the Belgian Hematological Society, Brussels, Belgium.

WILLEMS, E., CASTERMANS, E., Baron, F., BAUDOUX, E., Wanten, N., Bonnet, C., HAFRAOUI, K., Frère, P., Fillet, G., & Beguin, Y. (2005). Nonmyeloablative stem cell transplantation with CD8-depleted or unmanipulated peripheral blood stem cells: a prospective randomized trial. Blood, 106 (1075).

Baron, F., Schaaf-Lafontaine, N., Humblet-Baron, S., Meuris, N., Castermans, E., Baudoux, E., Frere, P., Bours, V., Fillet, G., & Beguin, Y. (2003). T-cell reconstitution after unmanipulated, CD8-depleted or CD34-selected nonmyeloablative peripheral blood stem-cell transplantation. Transplantation, 76 (12), 1705-13. doi:10.1097/01.TP.0000093987.11389.F7

Geenen, V., Poulin, J. F., Dion, M. L., Martens, H., Castermans, E., Hansenne, I., Moutschen, M., Sekaly, R. P., & Cheynier, R. (2003). Quantification of T cell receptor rearrangement excision circles to estimate thymic function: an important new tool for endocrine-immune physiology. Journal of Endocrinology, 176 (3), 305-311. doi:10.1677/joe.0.1760305