Reference : Fagraldehyde, a Secoiridoid Isolated from Fagraea fragrans
Scientific journals : Article
Human health sciences : Pharmacy, pharmacology & toxicology
http://hdl.handle.net/2268/9977
Fagraldehyde, a Secoiridoid Isolated from Fagraea fragrans
English
Jonville, Marie mailto [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
Capel, Marie [Université de Liège]
Frederich, Michel mailto [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
Angenot, Luc mailto [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
Dive, Georges mailto [Université de Liège - ULg > > Centre d'ingénierie des protéines >]
Faure, Robert [Université Paul Cézanne]
Azas, Nadine [Université de la Méditerranée > Pharmacie > Parasitologie > >]
Ollivier, Evelyne [Université de la Méditerranée > Pharmacie > Pharmacognosie > >]
Nov-2008
Journal of Natural Products
71
12
2038-2040
Yes (verified by ORBi)
International
0163-3864
1520-6025
[en] Fagraea fragrans ; Secoiridoid aglycone
[en] A secoiridoid aglycone with atypical skeleton, named fagraldehyde (1), together with several known secoiridoids (gentiopicroside (2), sweroside (3) and swertiamarin (4)) were isolated from the bark and leaves of Fagraea fragrans collected in Cambodia. The conformations of 1 were evaluated on the basis of molecular modeling and NOESY correlations. A hypothetical biogenesis of fagraldehyde was proposed to explain the unusual skeleton. Compound 1 was weakly active in vitro against Plasmodium falciparum.
Researchers ; Professionals
http://hdl.handle.net/2268/9977

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Restricted access
version journal imprimé.pdfPublisher postprint205.23 kBRequest copy

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.