Reference : Hypnotic modulation of resting state fMRI default mode and extrinsic network connectivity
Scientific journals : Article
Social & behavioral sciences, psychology : Neurosciences & behavior
http://hdl.handle.net/2268/99391
Hypnotic modulation of resting state fMRI default mode and extrinsic network connectivity
English
Demertzi, Athina mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Soddu, Andrea mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
FAYMONVILLE, Marie-Elisabeth mailto [Centre Hospitalier Universitaire de Liège - CHU > > Algologie - soins palliatifs >]
Bahri, Mohamed Ali mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Gosseries, Olivia mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Vanhaudenhuyse, Audrey mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Phillips, Christophe mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Maquet, Pierre mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Luxen, André mailto [Université de Liège - ULg > Département de chimie (sciences) > Chimie organique de synthèse >]
Laureys, Steven mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
23-Aug-2011
Progress in Brain Research
Elsevier
193
309-322
Yes (verified by ORBi)
International
0079-6123
1875-7855
Amsterdam
The Netherlands
[en] consciousness ; hypnotic state ; awareness ; fMRI ; default mode network ; functional connectivity.
[en] Resting state fMRI (functional magnetic resonance imaging) acquisitions are characterized by
low-frequency spontaneous activity in a default mode network (encompassing medial brain areas and linked to self-related processes) and an anticorrelated “extrinsic” system (encompassing lateral frontoparietal areas and modulated via external sensory stimulation). In order to better determine the functional contribution of these networks to conscious awareness, we here sought to transiently modulate their relationship by means of hypnosis. We used independent component analysis (ICA) on resting state fMRI acquisitions during normal wakefulness, under hypnotic state, and during a control condition of autobiographical mental imagery. As compared to mental imagery, hypnosis-induced modulation of resting state fMRI networks resulted in a reduced “extrinsic” lateral frontoparietal cortical connectivity, possibly reflecting a decreased sensory awareness. The default mode network showed an increased connectivity in bilateral angular and middle frontal gyri, whereas its posterior midline and parahippocampal structures decreased their connectivity during hypnosis, supposedly related to an altered “self” awareness and posthypnotic amnesia. In our view, fMRI resting state studies of physiological (e.g., sleep or hypnosis), pharmacological (e.g., sedation or anesthesia), and pathological modulation (e.g., coma or related states) of “intrinsic” default mode and anticorrelated “extrinsic” sensory networks, and their interaction with other cerebral networks, will further improve our understanding of the neural correlates of subjective awareness.
http://hdl.handle.net/2268/99391
10.1016/B978-0-444-53839-0.00020-X

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