Reference : Chitosan and chitosan derivatives in drug delivery and tissue engineering
Parts of books : Contribution to collective works
Physical, chemical, mathematical & earth Sciences : Chemistry
Engineering, computing & technology : Materials science & engineering
http://hdl.handle.net/2268/98122
Chitosan and chitosan derivatives in drug delivery and tissue engineering
English
Riva, Raphaël [University of Liège (ULg) > Department of Chemistry > Center for Education and Research on Macromolecules (CERM) > >]
Raguelle, Héloïse [Université catholique de Louvain (UCL), Brussels > Louvain Drug Research Institute (LDRI) > > >]
des Rieux, Anne [Université catholique de Louvain (UCL), Brussels > Louvain Drug Research Institute (LDRI) > > >]
Duhem, Nicolas [Université catholique de Louvain (UCL), Brussels > Louvain Drug Research Institute (LDRI) > > >]
Jérôme, Christine mailto [University of Liège (ULg) > Department of Chemistry > Center for Education and Research on Macromolecules (CERM) > >]
Préat, Véronique [Université catholique de Louvain (UCL), Brussels > Louvain Drug Research Institute (LDRI) > > >]
2011
Chitosan for Biomaterials II
Jayakumar, Rangasamy
Prabaharan, M.
Muzzarelli, Ricardo A. A.
Springer
Advances in Polymer Sciences, 244
19-44
978-3-642-24060-7
[en] biomaterial ; nanomedicine ; chitosan
[en] Chitosan is a nontoxic, biodegradable, and biocompatible polysaccharide of β(1-4)-linked d-glucosamine and N-acetyl-d-glucosamine. This derivative of natural chitin presents remarkable properties that have paved the way for the introduction of chitosan in the biomedical and pharmaceutical fields. Nevertheless, the properties of chitosan, such as its poor solubility in water or in organic solvents, can limit its utilization for a specific application. An elegant way to improve or to impart new properties to chitosan is the chemical modification of the chain, generally by grafting of functional groups, without modification of the initial skeleton in order to conserve the original properties. The functionalization is carried out on the primary amine group, generally by quaternization, or on the hydroxyl group. This review aims to provide an overview of chitosan and chitosan derivatives used for drug delivery, with a special emphasis on chemical modifications of chitosan to achieve specific biomedical purpose. The synthesis of the main chitosan derivatives will be reviewed. The applications of chitosan and these chitosan derivatives will be illustrated.
Center for Education and Research on Macromolecules (CERM)
Researchers
http://hdl.handle.net/2268/98122
10.1007/978-3-642-24061-4
http://www.springerlink.com/content/832g15l55w051685/fulltext.pdf

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Restricted access
Riva R 2001 Adv Polym Sci 244,19.pdfPublisher postprint518.07 kBRequest copy

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.