ORBi: Valdes Eduardo F - Disfuncion ventricular en la infeccion HIV perinatal

Reference : Disfuncion ventricular en la infeccion HIV perinatal


	Document type :	Scientific journals : Article
	Discipline(s) :	Human health sciences : General & internal medicine
	To cite this reference:	http://hdl.handle.net/2268/97126

Title :	Disfuncion ventricular en la infeccion HIV perinatal
Language :	English
Alternative title :	[en] Perinatal ventricular dysfonction in HIV infection
Author, co-author :	Valdes, Eduardo F [Hospital Rivadavia > Departamento de Medicina Interna > > >]
	Fernandez Rostello, Eduardo [ > > ]
	Romero Villanueva, Horacio [ > > ]
	Levin, Celina [ > > ]
	Goni Quintana, Cristina [ > > ]
	VALDES SOCIN, Hernan Gonzalo [Hospital de Clinicas "Jose de San Martin". Universidad de Buenos Aires > Departamento de Medicina Interna > Va Catedra de Medicina Interna > >]
	Bernabo, Jorge Guillermo [ > > ]
Publication date :	1995
Journal title :	Prensa Medica Argentina
Publisher :	Prensa Medica Argentina
Volume :	82
Pages :	791-794
Peer reviewed :	Yes (verified by ORBi)
Audience :	National
ISSN :	0032-745X
City :	Buenos Aires
Country :	Argentina
Keywords :	[en] hiv, aids, echo doppler, myocardiopathy, opportunistic infections, physiopathology, children, baby, pediatric.
Abstract :	[en] We studied cardiovascular function in four babies . There were three females (3, 6 and 9 months old ) and one 6 months old male with HIV perinatal infection (ELISA and Western blot positives). CD4 counts were: 1150/mm3, 1250 /mm3, 950/mm3 and 1066/mm3 respectively. The first baby had pneumocystosis and oral candidiasis, and two other had bacterial pneumonia and viral brochiolitis as antecedents. We observed after echocardiographic Doppler evaluation right ventricle diastolic dysfunction in three cases. Interestingly there were no pulmonary hypertension. Diastolic and systolic left ventricle function was normal in all babies. Our previous results in 27 AIDS adult patients let us to identify mainly left ventricle dysfunction (Valdes E & al Prensa Medica Argentina 1994). On the contrary, right ventricle dysfunction was predominant in this small series. Lipshultz & al (Am J Cardio 1990) found in 31 perinatal AIDS ventricular dysfunction, myocardial dilatation, arrhythmias and pericardial effusion. Our results combined with a literature review point out cardiac dysfunction as a frequent finding in children with AIDS. As these alterations are not necessarily clinically apparent, we recommend routine echocardiographic evaluation in these patients. Physiopathological clues in AIDS cardiac dysfunction remain elusive: HIV cytotoxic myocardiopathy, opportunistic infections and/or viral autoimmune mechanisms have been considered as potential causes.
Target :	Researchers ; Professionals ; Students
Permalink :	http://hdl.handle.net/2268/97126

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