Article (Scientific journals)
Posttraumatic Parathyroid Crisis and Severe Hypercalcemia Treated with Intravenous Bisphosphonate (Apd). Case Report
Canivet, Jean-Luc; Damas, Pierre; Lamy, Maurice
1990In Acta Anaesthesiologica Belgica, 41 (1), p. 47-50
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Keywords :
Hypercalcemia; Bisphosphonate; Trauma
Abstract :
[en] te hypercalcemia (4.03 mmol/l) developed in a 50 years old woman after head and intraabdominal trauma (and splenectomy). After failure to correct the calcium levels by intravenous saline, furosemide, steroids and calcitonin, two hemodialyses were performed; definitive control of hypercalcemia was obtained by intravenous (3-amino-1-hydroxypropylidene)-1.1-bisphosphonic acid (APD). APD is a new drug analog of pyrophosphate; its main property is to block bone resorption, irrespective of its stimulus. As suspected by clinical and laboratory data and confirmed by arteriographic findings, surgery and pathologic examination, the underlying pathology was a mild primary hyperparathyroidism which was acutely worsened (parathyroid crisis) in the course of the trauma. Definitive treatment consisted of the removal of the adenoma responsible of the hyperparathyroidism.
Disciplines :
Anesthesia & intensive care
Author, co-author :
Canivet, Jean-Luc ;  Centre Hospitalier Universitaire de Liège - CHU > Soins intensifs
Damas, Pierre ;  Université de Liège - ULiège > Département des sciences cliniques > Anesthésie et réanimation
Lamy, Maurice ;  Université de Liège - ULiège > Département des sciences cliniques > Anesthésie et réanimation
Language :
English
Title :
Posttraumatic Parathyroid Crisis and Severe Hypercalcemia Treated with Intravenous Bisphosphonate (Apd). Case Report
Publication date :
1990
Journal title :
Acta Anaesthesiologica Belgica
ISSN :
0001-5164
eISSN :
2736-5239
Publisher :
Acta Medica Belgica, Bruxelles, Belgium
Volume :
41
Issue :
1
Pages :
47-50
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 25 March 2009

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