Reference : Is posterior cerebral hypometabolism always predicitve of dementia in Parkinson's disease?
Scientific congresses and symposiums : Poster
Human health sciences : Neurology
http://hdl.handle.net/2268/95687
Is posterior cerebral hypometabolism always predicitve of dementia in Parkinson's disease?
English
[fr] L'hypométabolisme cérébral des régions postérieures est-il toujours prédictif d'une démence dans la maladie de Parkinson?
Deville, Benjamin mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Lemaire, Christian mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Degueldre, Christian mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Salmon, Eric mailto [Université de Liège - ULg > Département des sciences cliniques > Neuroimagerie des troubles de la mémoire et révalid. cogn. >]
Garraux, Gaëtan mailto [Université de Liège - ULg > Département des sciences cliniques > Neurologie >]
8-Jun-2010
231,1 x 114,3 cm
No
No
International
15th International Congres of Parkinson's disease and Movement Disorders
Du 5 juin 2011 au 9 juin 2011
Movement Disorders Society
Toronto
Canada
[en] Parkinson's disease ; Dementia ; Positron Emission Tomography
[en] In Parkinson's disease, altered activity in posterior associative cortices has often been associated with dementia. It remains to be determined if this pattern is a reliable marker of a progression toward dementia in patients without demonstratable dementia. In this retrospective analysis, we used positron emission tomography to study resting-state cerebral fluodeoxyglucose uptake in 8 healthy controls and 8 Parkinson's disease patients who did not have evidence of dementia at the time of assessment. For those patients, clinical follow up was available and we know that they did not meet dementia criteria on average 10,37 years after assessment. The results show that patients had reduced fluodeoxyglucose uptake mostly localised in the right hemisphere and including precuneus, superior temporal, middle temporal and inferior parietal cortices. It also includes right insula. These cerebral activity predominating in posterior cortices is present in non-demened patients but is not always predictive of dementia within the 10,34 years.
Centre de Recherches du Cyclotron - CRC
Researchers ; Professionals
http://hdl.handle.net/2268/95687

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