Abstract :
[en] BACKGROUND: Skin and bone may be affected similarly during the climacteric and
during long-term corticotherapy. Little is known about the correlation between
the respective alterations in bone mass density (BMD) and tensile strength of the
skin. MATERIALS AND METHODS: A total of 100 women aged 19-88 years, receiving, or
not, hormone replenishment therapy or systemic corticosteroids, were enrolled in
the study. Tensile strength of the inner forearm skin was measured using the
suction method operated in both the steep and progressive-force application
modes. BMD was measured by dual X-ray absorptiometry at the hip, femoral neck and
lumbar spine. RESULTS: Being heterogeneous, the population of volunteers yielded
a wide range of BMD and cutaneous tensile strength values. However, significant
correlations were found between BMD and tensile skin parameters. In particular, a
positive correlation was yielded between the biological elasticity of skin and
the BMD of the hip and femoral neck. CONCLUSION: An overall correlation is shown
between skin elasticity on a relatively sun-protected area and cortico-trabecular
BMD.
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