Reference : Les neuroblastomes de l'enfant. A propos de 23 cas.
Scientific journals : Article
Human health sciences : Hematology
http://hdl.handle.net/2268/9390
Les neuroblastomes de l'enfant. A propos de 23 cas.
French
[en] Clinical evaluation of 23 children with neuroblastoma. The experience of a single institution
Piette, Catherine mailto [Centre Hospitalier Universitaire de Liège - CHU > > Psychiatrie et psychologie médicale >]
Dresse, Marie-Françoise mailto [Centre Hospitalier Universitaire de Liège - CHU > > Pédiatrie CHR >]
Forget, Patricia mailto [Centre Hospitalier Universitaire de Liège - CHU > > Pédiatrie CHR >]
Schmitz, Véronique mailto [> > > >]
Demarche, Martine mailto [> > > >]
Erpicum, Patrice mailto [> > > >]
Closon, Marie-Thérèse mailto [Centre Hospitalier Universitaire de Liège - CHU > > Radiothérapie >]
Rutten, Isabelle [> > > >]
Paulus, Patrick mailto [> > > >]
Vivegnis, Danielle mailto [> > > >]
Beguin, Yves mailto [Centre Hospitalier Universitaire de Liège - CHU > > Hématologie clinique >]
Jamblin, Paul mailto [> > > >]
Hoyoux, Claire mailto [> > > >]
2005
Revue Médicale de Liège
60
3
173-80
Yes (verified by ORBi)
0370-629X
Belgium
[en] Abdominal Neoplasms/diagnosis/genetics/therapy ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Neuroblastoma/diagnosis/genetics/therapy ; Retrospective Studies ; Thoracic Neoplasms/diagnosis/genetics/therapy
[en] In this retrospective study, we analyse epidemiology, clinical symptoms and therapeutic results in a group of 23 children with neuroblastoma. Half of them were less than 2 years of age; in 19 of 23, the primitive tumour was abdominal; 35% of them were initially metastatic. The overall survival was 83% at 5 years and the event free survival, 75% at 5 years. Pronostic factors are age, extension of the disease at diagnosis, biologic parameters and genetic study of the neuroblast cells (amplification of N-myc oncogen). Our study shows the deleterious effect of bone lesions.
http://hdl.handle.net/2268/9390

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