ORBi: Lebrun Pierre - Validation and Routine of Ligand-Binding Assays, a Bayesian Perspective

Reference : Validation and Routine of Ligand-Binding Assays, a Bayesian Perspective


	Document type :	Scientific congresses and symposiums : Unpublished conference
	Discipline(s) :	Physical, chemical, mathematical & earth Sciences : Mathematics
	To cite this reference:	http://hdl.handle.net/2268/93792

Title :	Validation and Routine of Ligand-Binding Assays, a Bayesian Perspective
Language :	English
Author, co-author :	Lebrun, Pierre [Université de Liège - ULg > Département de pharmacie > Chimie analytique >]
	Boulanger, Bruno [ > > ]
	Hubert, Philippe [Université de Liège - ULg > Département de pharmacie > Chimie analytique >]
Publication date :	29-Apr-2011
On invitation :	Yes
Audience :	International
Event name :	Bayes 2011
Event date :	from 27-05-2011 to 29-05-2011
Event place (city) :	Louvain-la-Neuve
Event country :	Belgium
Abstract :	[en] The way to apply Bayesian modeling is illustrated to validate a ligand-binding assay such as ELISA. Hierarchical non-linear model and the associated predictive distribution of back-calculated responses allow quantifying the total uncertainty of every future measurement with the assays, through the use of precision and risk profiles. It is also shown how the obtained posterior distribution of the parameters can be used as prior for new the calibration curves during routine.
Target :	Researchers ; Professionals ; Students
Permalink :	http://hdl.handle.net/2268/93792

File(s) associated to this reference

There are no fulltext file associated with this reference.

Additional material(s):

	File	Commentary	Version	Size	Access
Restricted access	Bayes 2011.pdf		-	4.74 MB	Request copy

All documents in ORBi are protected by a user license.