Reference : Validation and Routine of Ligand-Binding Assays, a Bayesian Perspective
Scientific congresses and symposiums : Unpublished conference
Physical, chemical, mathematical & earth Sciences : Mathematics
http://hdl.handle.net/2268/93792
Validation and Routine of Ligand-Binding Assays, a Bayesian Perspective
English
Lebrun, Pierre mailto [Université de Liège - ULg > Département de pharmacie > Chimie analytique >]
Boulanger, Bruno mailto [ > > ]
Hubert, Philippe mailto [Université de Liège - ULg > Département de pharmacie > Chimie analytique >]
29-Apr-2011
Yes
Yes
International
Bayes 2011
from 27-05-2011 to 29-05-2011
Louvain-la-Neuve
Belgium
[en] The way to apply Bayesian modeling is illustrated to validate a ligand-binding assay such as ELISA. Hierarchical non-linear model and the associated predictive distribution of back-calculated responses allow quantifying the total uncertainty of every future measurement with the assays, through the use of precision and risk profiles. It is also shown how the obtained posterior distribution of the parameters can be used as prior for new the calibration curves during routine.
Researchers ; Professionals ; Students
http://hdl.handle.net/2268/93792

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