[en] Administration, Topical ; Betamethasone/administration & dosage/analogs & derivatives/therapeutic use ; Calcitriol/administration & dosage/analogs & derivatives/therapeutic use ; Drug Therapy, Combination ; Humans ; Inflammation ; Psoriasis/drug therapy
[en] The topical treatment of psoriasis benefits from the alternate use of dermocorticosteroids and vitamin D3 analogues. A new galenic formulation allows to combine them in a single application. Dovobet (LEO Pharma) ointment is the association of calcipotriol 50 microg/g with betamethasone dipoprionate 0.5 mg/g. This formulation boosts the therapeutic activity of calcipotriol. It also decreases the irritative inflammatory reaction due to calcipotriol without increasing the atrophogenic risk of the dermocorticoid.