Reference : Sensitivity analysis of phase response curves

	Document type :	Scientific congresses and symposiums : Unpublished conference
	Discipline(s) :	Engineering, computing & technology : Multidisciplinary, general & others
	To cite this reference:	http://hdl.handle.net/2268/93312

Title :	Sensitivity analysis of phase response curves
Language :	English
Author, co-author :	Sacré, Pierre [Université de Liège - ULg > Dép. d'électric., électron. et informat. (Inst.Montefiore) > Systèmes et modélisation >]
	Sepulchre, Rodolphe [Université de Liège - ULg > Dép. d'électric., électron. et informat. (Inst.Montefiore) > Systèmes et modélisation >]
Publication date :	23-May-2011
Audience :	International
Event name :	SIAM Conference on Applications of Dynamical Systems
Event place (city) :	Snowbird
Event country :	UT
Abstract :	[en] The Phase Response Curve (PRC) has proven a useful tool for the reduction of complex oscillator models to one-dimensional phase models. We introduce the sensitivity analysis of this important mathematical object and its numerical implementation. As an application, we study simple biochemical models of circadian oscillators and discuss how sensitivity analysis helps drawing connections between the state-space model of the oscillator and its phase response curve.
Permalink :	http://hdl.handle.net/2268/93312

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