Article (Scientific journals)
Comparative study on the enantioseparation of glutethimide using dual cyclodextrin systems and cyclodextrin modified MEKC in capillary electrophoresis
Abushoffa, Adel M.; Burjanadze, Naira; Blaschke, Gottfried et al.
2002In Journal of Separation Science, 25 (1-2), p. 10-16
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Keywords :
capillary electrophoresis; cyclodextrins; dual cyclodextrin systems; enantioseparation; MEKC
Abstract :
[en] In order to critically evaluate the potential of dual cyclodextrin (CD) systems in CE, enantioseparation of the neutral chiral analyte glutethimide (GT) was performed using: a) charged CDs; b) combinations of charged and neutral CDs (dual CD systems), and c) CD-modified micellar electrokinetic chromatography (CD-MECK). The results of this comparative study indicate that properly designed dual CD systems may in certain cases represent a valuable alternative to CD-MEKC and electrokinetic chromatography involving charged CDs for enantioseparation of neutral analytes.
Disciplines :
Chemistry
Author, co-author :
Abushoffa, Adel M.
Burjanadze, Naira
Blaschke, Gottfried
Crommen, Jacques ;  Université de Liège - ULiège > Département de pharmacie > Analyse des médicaments
Chankvetadze, Bezhan
Language :
English
Title :
Comparative study on the enantioseparation of glutethimide using dual cyclodextrin systems and cyclodextrin modified MEKC in capillary electrophoresis
Publication date :
January 2002
Journal title :
Journal of Separation Science
ISSN :
1615-9306
eISSN :
1615-9314
Publisher :
Wiley-V C H Verlag Gmbh, Weinheim, Germany
Volume :
25
Issue :
1-2
Pages :
10-16
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 17 March 2009

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