Reference : In vivo antimalarial activity of isosungucine, an indolomonoterpenic alkaloid from St...
Scientific journals : Article
Life sciences : Phytobiology (plant sciences, forestry, mycology...)
Physical, chemical, mathematical & earth Sciences : Chemistry
Human health sciences : Pharmacy, pharmacology & toxicology
http://hdl.handle.net/2268/8943
In vivo antimalarial activity of isosungucine, an indolomonoterpenic alkaloid from Strychnos icaja
English
Philippe, Geneviève mailto [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
De Mol, Patrick mailto [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Microbiologie médicale et virologie médicale]
Angenot, Luc mailto [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
Tits, Monique mailto [Université de Liège - ULg > Département de pharmacie > Phytochimie et phytothérapie >]
Frederich, Michel mailto [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
May-2007
Planta Medica
Georg Thieme Verlag Kg
73
5
478-479
Yes (verified by ORBi)
International
0032-0943
Stuttgart
[en] indolomonoterpenoid ; indole alkaloid ; strychnos ; antiplasmodial activity ; Plasmodium falciparum ; antimalarial
[en] Isosungucine (1) is a quasi-symmetric bisindolomonoterpenoid alkaloid isolated from the roots of Strychnos icaja. The in vivo antimalarial activity against the P. vinckei petteri murine strain was determined. In the Peters 4-day suppressive test, 1 suppressed the parasitemia by almost 50 percent on day 4 at the dose of 30 mg/kg by intraperitoneal route.
http://hdl.handle.net/2268/8943

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