Reference : Breast cancer and serum organochlorine residues
Scientific journals : Article
Human health sciences : Public health, health care sciences & services
http://hdl.handle.net/2268/8908
Breast cancer and serum organochlorine residues
English
Charlier, Corinne mailto [Université de Liège - ULg > Département de pharmacie > Chimie toxicologique]
Albert, Adelin mailto [Université de Liège - ULg > Département des sciences de la santé publique > Informatique médicale et biostatistique >]
Herman, Philippe [Université de Liège - ULg > Services généraux (Faculté de médecine) > Relations académiques et scientifiques (Médecine)]
Hamoir, Etienne mailto [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation >]
Gaspard, Ulysse mailto [Université de Liège - ULg > Services généraux (Faculté de médecine) > Relations académiques et scientifiques (Médecine)]
Meurisse, Michel mailto [Université de Liège - ULg > Département des sciences cliniques > Chirurgicale abdominale]
Plomteux, Guy mailto [Université de Liège - ULg > Services généraux (Faculté de médecine) > Relations académiques et scientifiques (Médecine) >]
May-2003
Occupational and Environmental Medicine
British Med Journal Publ Group
60
5
348-351
Yes (verified by ORBi)
International
1351-0711
London
[en] Background: Controversy still exists about the breast carcinogenic properties in humans of environmental xenoestrogens (organochlorines), justifying new investigations. Aims: To compare the blood levels of total dichlorodiphenyltrichloroethane (DDT) and hexachlorobenzene (HCB) in samples collected at the time of breast cancer discovery, in order to avoid the potential consequences of body weight change ( after chemotherapy or radiotherapy) on the pesticide residue levels. Methods: Blood levels of HCB and total DDT (we calculated total DDT concentrations by adding all DDT and DDE isomers) were compared in 159 women with breast cancer and 250 presumably healthy controls. Risk of breast cancer associated with organochlorine concentration was evaluated. Results: Mean levels of total DDT and HCB were significantly higher for breast cancer patients than for controls. No differences in serum levels of total DDT or HCB were found between oestrogen receptor positive and oestrogen receptor negative patients with breast cancer. Conclusions: These results add to the growing evidence that certain persistent pollutants may occur in higher concentrations in blood samples from breast cancer patients than controls.
http://hdl.handle.net/2268/8908

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Open access
Cancer sein, OEM.pdfNo commentaryPublisher postprint172.9 kBView/Open

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.