Reference : Effects of surgery on ischaemic mitral regurgitation: a prospective multicentre regis...
Scientific journals : Article
Human health sciences : Cardiovascular & respiratory systems
http://hdl.handle.net/2268/87938
Effects of surgery on ischaemic mitral regurgitation: a prospective multicentre registry (SIMRAM registry).
English
Lancellotti, Patrizio mailto [Centre Hospitalier Universitaire de Liège - CHU > > Cardiologie >]
Donal, Erwan [> > > >]
Cosyns, Bernard [> > > >]
Van Camp, Guy [> > > >]
Monin, Jean-Luc [> > > >]
Brochet, Eric [> > > >]
Berrebi, Alain [> > > >]
Pibarot, Philippe [> > > >]
Chauvel, Christophe [> > > >]
Hassager, Christian [> > > >]
Tumminello, Gabriele [> > > >]
Tribouilloy, Christophe [> > > >]
Lafitte, Stephane [> > > >]
Fraser, Alan G [> > > >]
Derumeaux, Genevieve [> > > >]
Athanassopoulos, George [> > > >]
Bax, Jeroen [> > > >]
Pierard, Luc mailto [Université de Liège - ULg > Département des sciences cliniques > Cardiologie - Pathologie spéciale et réhabilitation >]
2008
European Journal of Echocardiography
Harcourt Publishers Limited
9
1
26-30
Yes (verified by ORBi)
International
1525-2167
1532-2114
[en] Canada ; Coronary Artery Bypass ; Echocardiography, Doppler ; Europe ; Exercise Test ; Female ; Humans ; Male ; Mitral Valve Insufficiency/physiopathology/surgery/ultrasonography ; Myocardial Ischemia/physiopathology/surgery/ultrasonography ; Prospective Studies ; Registries ; Treatment Outcome
[en] AIMS: Functional ischaemic mitral regurgitation (IMR) is common in patients with ischaemic left ventricular dysfunction undergoing coronary artery bypass surgery. Although the presence of IMR negatively affects prognosis, the additional benefit of valve repair is debated, particularly with mild IMR at rest. Exercise echocardiography may help identify a subset of patients at higher risk of cardiovascular events by revealing the dynamic component of IMR. METHODS: A large prospective, multicentre, non-randomized registry is designed to evaluate the effects of surgery on IMR at rest and on its dynamic component at exercise (z). SIMRAM will enrol approximately 550 patients with IMR in up to 17 centres with clinical and exercise follow-up for 1 year. Three sets of outcomes will be prospectively assessed and several hypotheses will be tested including determinants of adverse outcome and progressive left ventricular remodeling, efficacy of treatment and role of ischaemia on the dynamic consequences of IMR. Enrolment began in November 2006 and is expected to end by early 2008.
http://hdl.handle.net/2268/87938
10.1016/j.euje.2006.12.009

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