Reference : Distribution of basement membrane antigens in glomeruli of mice with autoimmune glomerul...
Scientific journals : Article
Life sciences : Biochemistry, biophysics & molecular biology
http://hdl.handle.net/2268/87670
Distribution of basement membrane antigens in glomeruli of mice with autoimmune glomerulonephritis.
English
Matsuo, S. [ > > ]
Brentjens, J. R. [ > > ]
Andres, G. [ > > ]
Foidart, Jean-Michel mailto [Université de Liège - ULg > Département des sciences cliniques > Gynécologie - Obstétrique >]
Martin, G. R. [ > > ]
Martinez-Hernandez, A. [ > > ]
1986
American Journal of Pathology
American Society for Investigative Pathology
122
1
36-49
Yes (verified by ORBi)
International
0002-9440
1525-2191
Bethesda
MD
[en] Glomerulonephritis was induced in mice by the repeated injection of human glomeruli or purified glomerular basement membrane. The glomerular basement membranes of nephritic animals were observed to develop subepithelial extensions, "spikes." Although normally Type IV collagen is found throughout the full thickness of basement membranes, the "spikes" reacted with antibodies to laminin but not with antibodies to Type IV collagen. It is proposed that in murine autoimmune glomerulonephritis, the visceral epithelial cells produce an excess of laminin.
http://hdl.handle.net/2268/87670

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