Article (Scientific journals)
Distribution of basement membrane antigens in glomeruli of mice with autoimmune glomerulonephritis.
Matsuo, S.; Brentjens, J. R.; Andres, G. et al.
1986In American Journal of Pathology, 122 (1), p. 36-49
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Abstract :
[en] Glomerulonephritis was induced in mice by the repeated injection of human glomeruli or purified glomerular basement membrane. The glomerular basement membranes of nephritic animals were observed to develop subepithelial extensions, "spikes." Although normally Type IV collagen is found throughout the full thickness of basement membranes, the "spikes" reacted with antibodies to laminin but not with antibodies to Type IV collagen. It is proposed that in murine autoimmune glomerulonephritis, the visceral epithelial cells produce an excess of laminin.
Disciplines :
Biochemistry, biophysics & molecular biology
Author, co-author :
Matsuo, S.
Brentjens, J. R.
Andres, G.
Foidart, Jean-Michel ;  Université de Liège - ULiège > Département des sciences cliniques > Gynécologie - Obstétrique
Martin, G. R.
Martinez-Hernandez, A.
Language :
English
Title :
Distribution of basement membrane antigens in glomeruli of mice with autoimmune glomerulonephritis.
Publication date :
1986
Journal title :
American Journal of Pathology
ISSN :
0002-9440
eISSN :
1525-2191
Publisher :
American Society for Investigative Pathology, Bethesda, United States - Maryland
Volume :
122
Issue :
1
Pages :
36-49
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 24 March 2011

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