Reference : Gamma-probe-directed lymphatic mapping and sentinel lymphadenectomy in primary cutaneous...
Scientific journals : Article
Human health sciences : Dermatology
http://hdl.handle.net/2268/87571
Gamma-probe-directed lymphatic mapping and sentinel lymphadenectomy in primary cutaneous melanoma.
English
Belhocine, T. [Centre Hospitalier Universitaire de Liège - CHU > > > > Médecine nucléaire > >]
Pierard, Gérald mailto [Centre Hospitalier Universitaire de Liège - CHU > > Dermatopathologie >]
Gielen, Jean-Louis mailto [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie maxillo-faciale et plastique >]
Daenen, Frédéric [Centre Hospitalier Universitaire de Liège - CHU > > Médecine nucléaire >]
De Barsy, C. [> > > >]
Arrese Estrada, Jorge [Centre Hospitalier Universitaire de Liège - CHU > > Dermatopathologie >]
Lahaye, Thierry [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie générale >]
Rigo, Pierre mailto [Université de Liège - ULg > Département des sciences de la motricité > Pathologie générale et médecine nucléaire >]
2002
Dermatology : International Journal for Clinical & Investigative Dermatology
S. Karger
204
4
355-61
Yes (verified by ORBi)
1018-8665
1421-9832
Basel
Switzerland
[en] Female ; Humans ; Lymph Node Excision ; Lymph Nodes/pathology/radionuclide imaging ; Lymphatic Metastasis ; Male ; Melanoma/radionuclide imaging/secondary ; Middle Aged ; Prognosis ; Sensitivity and Specificity ; Sentinel Lymph Node Biopsy ; Skin Neoplasms/pathology ; Survival Analysis
[en] BACKGROUND: Radiotracer and blue-dye lymphatic mapping is a recommended combined method to guide sentinel lymphadenectomy and full regional lymph node dissection in selected patients with cutaneous melanoma. OBJECTIVE: To evaluate the diagnostic accuracy and the prognostic value of gamma-probe-directed lymphatic mapping in cutaneous melanomas. METHODS: Sixty-five stage I and II melanoma patients underwent gamma-probe-directed lymphatic mapping. Sentinel lymph nodes were studied by both conventional and immunohistochemical stainings. The median follow-up was 11 months. RESULTS: Sensitivities of preoperative and intraoperative sentinel lymph node detection were 100 and 98%, respectively. Only 1 failure of detection and 1 missed same-basin metastasis were experienced in the axillary and cervical areas, respectively. Eleven patients (16.9%) had sentinel node metastases leading to adjuvant therapy. CONCLUSION: Gamma-probe-directed lymphatic mapping is useful for staging melanoma. However, in the expectation of a more specific identification of the sentinel lymph node, the standard protocol remains recommended for exploring the axillary and cervical areas. The histological examination supported in some cases by immunohistochemistry remains mandatory in all cases.
http://hdl.handle.net/2268/87571
Copyright 2002 S. Karger AG, Basel

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Restricted access
GAMMA PROBE.pdfPublisher postprint63.54 kBRequest copy

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.